PT2141172E - Inibidores da ciclopropil polimerase - Google Patents

Inibidores da ciclopropil polimerase

Info

Publication number: PT2141172E
Authority: PT; Portugal
Prior art keywords: cyclopropyl; polymerase inhibitors; polymerase; inhibitors; cyclopropyl polymerase
Prior art date: 2008-07-01

Application number

PT90086349T

Other languages

English (en)

Inventor

Pierre Jean-Marie Bernard Raboisson

Tim Hugo Maria Jonckers

Koen Vandyck

Original Assignee

Medivir Ab

Janssen Products Lp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-07-01

Filing date

2009-07-01

Publication date

2013-01-14

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41095413&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2141172(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-07-01 Application filed by Medivir Ab, Janssen Products Lp filed Critical Medivir Ab

2013-01-14 Publication of PT2141172E publication Critical patent/PT2141172E/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Molecular Biology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Genetics & Genomics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biotechnology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Oncology (AREA)
Bioinformatics & Cheminformatics (AREA)
Gastroenterology & Hepatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Saccharide Compounds (AREA)

PT90086349T 2008-07-01 2009-07-01 Inibidores da ciclopropil polimerase PT2141172E (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP08159396		2008-07-01
EP08171005		2008-12-08

Publications (1)

Publication Number	Publication Date
PT2141172E true PT2141172E (pt)	2013-01-14

Family

ID=41095413

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT90086349T PT2141172E (pt)	2008-07-01	2009-07-01	Inibidores da ciclopropil polimerase

Country Status (29)

Country	Link
US (1)	US8431588B2 (pt)
EP (1)	EP2141172B1 (pt)
JP (1)	JP5624029B2 (pt)
KR (1)	KR20110038683A (pt)
CN (2)	CN105693794A (pt)
AP (1)	AP2010005505A0 (pt)
AR (1)	AR072428A1 (pt)
AU (1)	AU2009266004B2 (pt)
BR (1)	BRPI0913643A2 (pt)
CA (1)	CA2729316A1 (pt)
CL (1)	CL2010001634A1 (pt)
CO (1)	CO6321255A2 (pt)
DK (1)	DK2141172T3 (pt)
EA (1)	EA022754B1 (pt)
EC (1)	ECSP10010725A (pt)
ES (1)	ES2396803T3 (pt)
HK (1)	HK1226080A1 (pt)
HR (1)	HRP20121068T1 (pt)
IL (1)	IL209932A (pt)
MX (1)	MX2010014493A (pt)
NI (1)	NI201000231A (pt)
PL (1)	PL2141172T3 (pt)
PT (1)	PT2141172E (pt)
SI (1)	SI2141172T1 (pt)
SV (1)	SV2010003779A (pt)
TW (1)	TW201012814A (pt)
UY (1)	UY31950A (pt)
WO (1)	WO2010000459A1 (pt)
ZA (1)	ZA201009294B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR102089887B1 (ko) *	2008-09-08	2020-03-16	사우디 아람코 테크놀로지스 컴퍼니	폴리카보네이트 폴리올 조성물
UY32099A (es)	2008-09-11	2010-04-30	Enanta Pharm Inc	Inhibidores macrocíclicos de serina proteasas de hepatitis c
TW201201815A (en) *	2010-05-28	2012-01-16	Gilead Sciences Inc	1'-substituted-carba-nucleoside prodrugs for antiviral treatment
KR20140003521A (ko)	2010-12-30	2014-01-09	이난타 파마슈티칼스, 인코포레이티드	페난트리딘 매크로사이클릭 ｃ형 간염 세린 프로테아제 억제제
EP2658859A4 (en)	2010-12-30	2014-07-30	Enanta Pharm Inc	MACROCYCLIC HEPATITIS C SERIN PROTEASE INHIBITORS
US10201584B1 (en)	2011-05-17	2019-02-12	Abbvie Inc.	Compositions and methods for treating HCV
JP5845841B2 (ja)	2011-11-18	2016-01-20	東芝ライテック株式会社	照明制御装置
AU2013221571A1 (en)	2012-02-14	2014-08-28	University Of Georgia Research Foundation, Inc.	Spiro [2.4] heptanes for treatment of Flaviviridae infections
WO2015103490A1 (en)	2014-01-03	2015-07-09	Abbvie, Inc.	Solid antiviral dosage forms
IL295418B2 (en)	2015-03-06	2023-10-01	Atea Pharmaceuticals Inc	Cell-D-2'-deoxy-2'-alpha-fluoro-2'-cell-C-modified-2-different-N6-purine modified nucleotides for the treatment of hepatitis C virus
RU2590952C1 (ru) *	2015-05-26	2016-07-10	Вячеслав Энгельсович Семёнов	Средство гепатопротекторного действия
LU100724B1 (en)	2016-07-14	2018-07-31	Atea Pharmaceuticals Inc	Beta-d-2'-deoxy-2'-alpha-fluoro-2'-beta-c-substituted-4'-fluoro-n6-substituted-6-amino-2-substituted purine nucleotides for the treatment of hepatitis c virus infection
PT3512863T (pt)	2016-09-07	2022-03-09	Atea Pharmaceuticals Inc	Nucleótidos de purina 2'-substituídos-n6-substituídos para tratamento de vírus de rna
KR102335193B1 (ko)	2017-02-01	2021-12-03	아테아 파마슈티컬즈, 인크.	C형 간염 바이러스를 치료하기 위한 뉴클레오티드 헤미-술페이트 염
CN112351799A (zh)	2018-04-10	2021-02-09	阿堤亚制药公司	具有硬化的hcv感染患者的治疗
US10874687B1 (en)	2020-02-27	2020-12-29	Atea Pharmaceuticals, Inc.	Highly active compounds against COVID-19

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100333016B1 (ko)	1992-12-29	2002-11-22	아보트 러보러터리즈	레트로바이러스성프로테아제억제화합물,이의제조방법및이를함유하는약제학적조성물
IL110752A (en)	1993-09-13	2000-07-26	Abbott Lab	Liquid semi-solid or solid pharmaceutical composition for an HIV protease inhibitor
US5559158A (en)	1993-10-01	1996-09-24	Abbott Laboratories	Pharmaceutical composition
IL111991A (en)	1994-01-28	2000-07-26	Abbott Lab	Liquid pharmaceutical composition of HIV protease inhibitors in organic solvent
US6037157A (en)	1995-06-29	2000-03-14	Abbott Laboratories	Method for improving pharmacokinetics
GB0114286D0 (en)	2001-06-12	2001-08-01	Hoffmann La Roche	Nucleoside Derivatives
DE14169110T1 (de)	2002-06-28	2022-05-12	Centre National De La Recherche Scientifique -Cnrs-	Modifizierte 2'- und 3'-Nukleosid-Prodrugs zur Behandlung von Flaviridae-Infektionen
CA2523083C (en) *	2003-04-25	2014-07-08	Gilead Sciences, Inc.	Antiviral phosphonate analogs
CA2577526A1 (en) *	2004-08-23	2006-03-02	Joseph Armstrong Martin	Antiviral 4'-azido-nucleosides
JP2010505902A (ja) *	2006-10-10	2010-02-25	メディヴィル・アクチエボラーグ	Ｈｃｖヌクレオシド阻害剤

2009
- 2009-06-30 UY UY0001031950A patent/UY31950A/es unknown
- 2009-06-30 TW TW098121932A patent/TW201012814A/zh unknown
- 2009-06-30 AR ARP090102442A patent/AR072428A1/es not_active Application Discontinuation
- 2009-07-01 WO PCT/EP2009/004748 patent/WO2010000459A1/en active Application Filing
- 2009-07-01 AU AU2009266004A patent/AU2009266004B2/en not_active Ceased
- 2009-07-01 PT PT90086349T patent/PT2141172E/pt unknown
- 2009-07-01 MX MX2010014493A patent/MX2010014493A/es active IP Right Grant
- 2009-07-01 EP EP09008634A patent/EP2141172B1/en active Active
- 2009-07-01 KR KR1020117002345A patent/KR20110038683A/ko not_active Application Discontinuation
- 2009-07-01 BR BRPI0913643A patent/BRPI0913643A2/pt not_active IP Right Cessation
- 2009-07-01 US US12/999,263 patent/US8431588B2/en not_active Expired - Fee Related
- 2009-07-01 CN CN201610033092.2A patent/CN105693794A/zh active Pending
- 2009-07-01 AP AP2010005505A patent/AP2010005505A0/xx unknown
- 2009-07-01 EA EA201170118A patent/EA022754B1/ru not_active IP Right Cessation
- 2009-07-01 CN CN200980125579.1A patent/CN102083845B/zh not_active Expired - Fee Related
- 2009-07-01 ES ES09008634T patent/ES2396803T3/es active Active
- 2009-07-01 PL PL09008634T patent/PL2141172T3/pl unknown
- 2009-07-01 JP JP2011515237A patent/JP5624029B2/ja not_active Expired - Fee Related
- 2009-07-01 SI SI200930467T patent/SI2141172T1/sl unknown
- 2009-07-01 DK DK09008634.9T patent/DK2141172T3/da active
- 2009-07-01 CA CA2729316A patent/CA2729316A1/en not_active Abandoned
2010
- 2010-12-12 IL IL209932A patent/IL209932A/en not_active IP Right Cessation
- 2010-12-22 SV SV2010003779A patent/SV2010003779A/es not_active Application Discontinuation
- 2010-12-23 CO CO10161808A patent/CO6321255A2/es not_active Application Discontinuation
- 2010-12-23 ZA ZA2010/09294A patent/ZA201009294B/en unknown
- 2010-12-23 NI NI201000231A patent/NI201000231A/es unknown
- 2010-12-29 EC EC2010010725A patent/ECSP10010725A/es unknown
- 2010-12-30 CL CL2010001634A patent/CL2010001634A1/es unknown
2012
- 2012-12-27 HR HRP20121068AT patent/HRP20121068T1/hr unknown
2016
- 2016-12-15 HK HK16114266A patent/HK1226080A1/zh unknown

Also Published As

Publication number	Publication date
AU2009266004A1 (en)	2010-01-07
EP2141172B1 (en)	2012-10-24
CO6321255A2 (es)	2011-09-20
CN105693794A (zh)	2016-06-22
EA022754B1 (ru)	2016-02-29
HRP20121068T1 (hr)	2013-01-31
CN102083845A (zh)	2011-06-01
EP2141172A1 (en)	2010-01-06
TW201012814A (en)	2010-04-01
SI2141172T1 (sl)	2013-02-28
AP2010005505A0 (en)	2010-12-31
AR072428A1 (es)	2010-08-25
PL2141172T3 (pl)	2013-03-29
DK2141172T3 (da)	2013-01-21
JP5624029B2 (ja)	2014-11-12
KR20110038683A (ko)	2011-04-14
WO2010000459A1 (en)	2010-01-07
JP2011526270A (ja)	2011-10-06
MX2010014493A (es)	2011-05-19
HK1226080A1 (zh)	2017-09-22
NI201000231A (es)	2011-09-03
CL2010001634A1 (es)	2011-08-05
IL209932A (en)	2013-12-31
ZA201009294B (en)	2012-06-27
BRPI0913643A2 (pt)	2015-11-24
SV2010003779A (es)	2011-02-08
CA2729316A1 (en)	2010-01-07
ECSP10010725A (es)	2011-04-29
US8431588B2 (en)	2013-04-30
UY31950A (es)	2010-01-29
IL209932A0 (en)	2011-02-28
AU2009266004B2 (en)	2014-01-30
US20110092460A1 (en)	2011-04-21
ES2396803T3 (es)	2013-02-27
CN102083845B (zh)	2016-09-14
EA201170118A1 (ru)	2011-06-30

Publication	Publication Date	Title
HK1226080A1 (zh)	2017-09-22	環丙基聚合酶抑制劑
HUS2000023I1 (hu)	2021-03-29	Beta-laktamáz inhibitorok
IL211070A0 (en)	2011-04-28	Dihydropyridophthalazinone inhibitors of poly(adp-ribose)polymerase
EP2396004A4 (en)	2012-07-25	SELECTIVE KINASE HEMMER
ZA201002638B (en)	2011-04-28	Viral polymerase inhibitors
ZA201100898B (en)	2012-02-29	Novel inhibitors
EP2185539A4 (en)	2011-07-20	VIRAL POLYMERASE INHIBITORS
EP2350039A4 (en)	2012-10-10	INHIBITORS OF VIRAL POLYMERASE
EP2188274A4 (en)	2011-05-25	VIRAL POLYMERASE HEMMER
GB0901898D0 (en)	2009-03-11	Dual calpain-ros inhibitors
ZA201303410B (en)	2014-03-26	Viral polymerase inhibitors
ZA201102837B (en)	2011-12-28	Phosphodiestarase inhibitors
GB0810011D0 (en)	2008-07-09	5-Lipoxygenase inhibitors
GB0901900D0 (en)	2009-03-11	Dual calpain-ros inhibitors
GB0806912D0 (en)	2008-05-21	Polymerase inhibitors
GB0806919D0 (en)	2008-05-21	Polymerase inhibitors
GB0806914D0 (en)	2008-05-21	Polymerase inhibitors
GB0806913D0 (en)	2008-05-21	Polymerase inhibitors
GB0806911D0 (en)	2008-05-21	Polymerase inhibitors
GB0806917D0 (en)	2008-05-21	Polymerase inhibitors
GB0806915D0 (en)	2008-05-21	Polymerase inhibitors
GB0806920D0 (en)	2008-05-21	Polymerase inhibitors
GB201019387D0 (en)	2010-12-29	Inhibitors
GB0902661D0 (en)	2009-04-01	Inhibitors
GB0903650D0 (en)	2009-04-15	Glyoalase inhibitors