PT2038423E - Método de produção de um polipéptido biologicamente activo possuindo actividade insulinotrópica - Google Patents

Método de produção de um polipéptido biologicamente activo possuindo actividade insulinotrópica

Info

Publication number
PT2038423E
PT2038423E PT78056256T PT07805625T PT2038423E PT 2038423 E PT2038423 E PT 2038423E PT 78056256 T PT78056256 T PT 78056256T PT 07805625 T PT07805625 T PT 07805625T PT 2038423 E PT2038423 E PT 2038423E
Authority
PT
Portugal
Prior art keywords
biologically active
active polypeptide
insulinotropic activity
producing biologically
producing
Prior art date
Application number
PT78056256T
Other languages
English (en)
Inventor
Ramakrishnan Melarkode
Akundi Venkata Sriram
Kedarnath Nanjund Sastry
Lakshmi Prabha Varadarajalu
Shrikumar Suryanarayan
Original Assignee
Biocon Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocon Ltd filed Critical Biocon Ltd
Publication of PT2038423E publication Critical patent/PT2038423E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
PT78056256T 2006-06-21 2007-06-20 Método de produção de um polipéptido biologicamente activo possuindo actividade insulinotrópica PT2038423E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN1057CH2006 2006-06-21

Publications (1)

Publication Number Publication Date
PT2038423E true PT2038423E (pt) 2013-03-27

Family

ID=38833862

Family Applications (1)

Application Number Title Priority Date Filing Date
PT78056256T PT2038423E (pt) 2006-06-21 2007-06-20 Método de produção de um polipéptido biologicamente activo possuindo actividade insulinotrópica

Country Status (9)

Country Link
US (1) US8114632B2 (pt)
EP (1) EP2038423B1 (pt)
CN (1) CN101501209B (pt)
DK (1) DK2038423T3 (pt)
ES (1) ES2401856T3 (pt)
HK (1) HK1132011A1 (pt)
PL (1) PL2038423T3 (pt)
PT (1) PT2038423E (pt)
WO (1) WO2007148345A2 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2494050A4 (en) * 2009-10-30 2013-10-30 Merck Sharp & Dohme FACTOR FOR STIMULATING GRANULOCYTES AND MONOCYTES PRODUCED IN GLYCOMODIFIED PICHIA PASTORIS
JP2013509181A (ja) * 2009-10-30 2013-03-14 メルク・シャープ・エンド・ドーム・コーポレイション ジペプチジルアミノペプチダーゼ活性を欠くピチア・パストリスにおける治療用タンパク質の製造方法
CN102639559B (zh) * 2009-11-25 2015-04-29 诺沃—诺迪斯克有限公司 用于制备多肽的方法
US9534039B2 (en) 2011-05-09 2017-01-03 Ablynx N.V. Method for the production of immunoglobulin single variable domains
UA116217C2 (uk) 2012-10-09 2018-02-26 Санофі Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
RU2652783C2 (ru) 2012-12-21 2018-05-03 Санофи Двойные агонисты glp1/gip или тройные агонисты glp1/gip/глюкагона
CN103911388B (zh) * 2013-10-16 2017-06-06 东莞市麦亘生物科技有限公司 重组艾塞那肽的生产工艺
WO2015086729A1 (en) 2013-12-13 2015-06-18 Sanofi Dual glp-1/gip receptor agonists
TW201609797A (zh) 2013-12-13 2016-03-16 賽諾菲公司 雙重ｇｌｐ－１／升糖素受體促效劑
WO2015086728A1 (en) 2013-12-13 2015-06-18 Sanofi Exendin-4 peptide analogues as dual glp-1/gip receptor agonists
TW201609796A (zh) 2013-12-13 2016-03-16 賽諾菲公司 非醯化之艾塞那肽－４（ｅｘｅｎｄｉｎ－４）胜肽類似物
TW201625670A (zh) 2014-04-07 2016-07-16 賽諾菲公司 衍生自ｅｘｅｎｄｉｎ－４之雙重ｇｌｐ－１／升糖素受體促效劑
TW201625668A (zh) 2014-04-07 2016-07-16 賽諾菲公司 作為胜肽性雙重ｇｌｐ－１／昇糖素受體激動劑之艾塞那肽－４衍生物
TW201625669A (zh) 2014-04-07 2016-07-16 賽諾菲公司 衍生自艾塞那肽－４（Ｅｘｅｎｄｉｎ－４）之肽類雙重ＧＬＰ－１／升糖素受體促效劑
US9932381B2 (en) 2014-06-18 2018-04-03 Sanofi Exendin-4 derivatives as selective glucagon receptor agonists
AR105319A1 (es) 2015-06-05 2017-09-27 Sanofi Sa Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico
TW201706291A (zh) 2015-07-10 2017-02-16 賽諾菲公司 作為選擇性肽雙重ｇｌｐ－１／升糖素受體促效劑之新毒蜥外泌肽（ｅｘｅｎｄｉｎ－４）衍生物
CN113462713B (zh) * 2021-09-06 2021-12-07 中国农业科学院生物技术研究所 提高胰高血糖素样肽六连体在毕赤酵母中表达水平的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5424286A (en) * 1993-05-24 1995-06-13 Eng; John Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same
DK0909312T3 (da) * 1996-07-05 2003-03-17 Novo Nordisk As Fremgangsmåde til fremstilling af polypeptider
WO1998035033A1 (en) 1997-02-05 1998-08-13 1149336 Ontario Inc. Polynucleotides encoding proexendin, and methods and uses thereof
US6723530B1 (en) * 1997-02-05 2004-04-20 Amylin Pharmaceuticals, Inc. Polynucleotides encoding proexendin, and methods and uses thereof
NZ502592A (en) 1997-08-08 2002-03-28 Amylin Pharmaceuticals Inc Exendin agonist peptides and their use in the treatment of type I and II diabetes
CN1198937C (zh) 1998-01-30 2005-04-27 第一三得利制药株式会社 利用辅助肽制造肽的方法
CA2391906A1 (en) * 1999-11-19 2001-05-25 Transkaryotic Therapies, Inc. Nucleic acid construct for optimized production of products
CN1363654A (zh) * 2001-07-19 2002-08-14 上海华谊生物技术有限公司 生产促胰岛素分泌肽glp－1(7－36)的基因工程菌以及生产glp－1(7－36)的方法
CN1233816C (zh) * 2002-04-16 2005-12-28 海南海梁生物高科技有限公司 酵母重组株及IFNα－la干扰素的纯化方法
EP1626981A4 (en) * 2003-03-04 2006-11-22 Biorexis Pharmaceutical Corp PROTEINS PROTECTED AGAINST DIPEPTIDYLPEPTIDASE
CN1268751C (zh) * 2003-05-26 2006-08-09 海南国栋药物研究所有限公司 表达人粒细胞巨噬细胞集落刺激因子的酵母重组株及rhGM－CSF的纯化方法
WO2005100388A1 (en) * 2004-04-19 2005-10-27 Biocon Limited Production of insulinotropic peptides
CN1318587C (zh) * 2004-04-30 2007-05-30 成都芝田生物工程有限公司 酰胺化Exendin－4多肽的重组制备方法
CN100535111C (zh) * 2004-11-03 2009-09-02 东莞太力生物工程有限公司 一种制备重组Exendin-4多肽的新工艺

Also Published As

Publication number Publication date
WO2007148345A3 (en) 2008-02-07
WO2007148345A2 (en) 2007-12-27
PL2038423T3 (pl) 2013-05-31
US20100167342A1 (en) 2010-07-01
EP2038423B1 (en) 2012-12-26
EP2038423A4 (en) 2009-12-09
CN101501209A (zh) 2009-08-05
HK1132011A1 (en) 2010-02-12
US8114632B2 (en) 2012-02-14
DK2038423T3 (da) 2013-04-02
ES2401856T3 (es) 2013-04-25
EP2038423A2 (en) 2009-03-25
CN101501209B (zh) 2013-06-05

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