PT1727555E - Produção de extractos de lúpulo tendo bioactividade oestrogénica e antiproliferativa - Google Patents

Produção de extractos de lúpulo tendo bioactividade oestrogénica e antiproliferativa Download PDF

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Publication number
PT1727555E
PT1727555E PT04802152T PT04802152T PT1727555E PT 1727555 E PT1727555 E PT 1727555E PT 04802152 T PT04802152 T PT 04802152T PT 04802152 T PT04802152 T PT 04802152T PT 1727555 E PT1727555 E PT 1727555E
Authority
PT
Portugal
Prior art keywords
production
oestrogenic
hop extracts
antiproliferative
bioactivity
Prior art date
Application number
PT04802152T
Other languages
English (en)
Inventor
Francis Maes
Denis De Keukeleire
Arne Heyerick
Original Assignee
Metagenics Belgium Bvba
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metagenics Belgium Bvba filed Critical Metagenics Belgium Bvba
Publication of PT1727555E publication Critical patent/PT1727555E/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Reproductive Health (AREA)
  • Medicines Containing Plant Substances (AREA)
PT04802152T 2003-12-16 2004-12-15 Produção de extractos de lúpulo tendo bioactividade oestrogénica e antiproliferativa PT1727555E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03447290A EP1543834A1 (en) 2003-12-16 2003-12-16 Production of hop extracts having oestrogenic and antiproliferative bioactivity

Publications (1)

Publication Number Publication Date
PT1727555E true PT1727555E (pt) 2009-08-05

Family

ID=34486584

Family Applications (1)

Application Number Title Priority Date Filing Date
PT04802152T PT1727555E (pt) 2003-12-16 2004-12-15 Produção de extractos de lúpulo tendo bioactividade oestrogénica e antiproliferativa

Country Status (18)

Country Link
US (2) US20070110835A1 (pt)
EP (2) EP1543834A1 (pt)
JP (2) JP5606660B2 (pt)
CN (1) CN1893963B (pt)
AT (1) ATE429924T1 (pt)
AU (1) AU2004298294B2 (pt)
CA (1) CA2549662C (pt)
DE (1) DE602004020930D1 (pt)
DK (1) DK1727555T3 (pt)
ES (1) ES2326375T3 (pt)
MX (1) MXPA06006782A (pt)
NZ (1) NZ548296A (pt)
PL (1) PL1727555T3 (pt)
PT (1) PT1727555E (pt)
RU (1) RU2370273C2 (pt)
UA (1) UA86607C2 (pt)
WO (1) WO2005058336A1 (pt)
ZA (1) ZA200605478B (pt)

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WO2000070531A2 (en) * 1999-05-17 2000-11-23 The Foxboro Company Methods and apparatus for control configuration
US6788980B1 (en) 1999-06-11 2004-09-07 Invensys Systems, Inc. Methods and apparatus for control using control devices that provide a virtual machine environment and that communicate via an IP network
US20040115290A1 (en) 2001-06-20 2004-06-17 Tripp Matthew L. Modulation of inflammation by hops fractions and derivatives
US8206753B2 (en) 2001-06-20 2012-06-26 Metaproteomics, Llc Anti-inflammatory botanical products for the treatment of metabolic syndrome and diabetes
US7901713B2 (en) 2001-06-20 2011-03-08 Metaproteomics, Llc Inhibition of COX-2 and/or 5-LOX activity by fractions isolated or derived from hops
US8142819B2 (en) 2002-10-21 2012-03-27 Metaproteomics, Llc Synergistic compositions that treat or inhibit pathological conditions associated with inflammatory response
US7901714B2 (en) 2001-06-20 2011-03-08 Metaproteomics, Llp Treatment modalities for autoimmune diseases
US8168234B2 (en) 2001-06-20 2012-05-01 Metaproteomics, Llc Compositions that treat or inhibit pathological conditions associated with inflammatory response
US8158160B2 (en) 2001-11-13 2012-04-17 Eric Hauser Kuhrts Anti-inflammatory cyclooxygenase inhibitors
CA2503196C (en) 2002-10-21 2011-08-02 Metaproteomics, Llc Compositions that treat or inhibit pathological conditions associated with inflammatory response
US7914831B2 (en) 2004-02-27 2011-03-29 Metaproteomics, Llc Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines
US20090274778A1 (en) * 2004-11-13 2009-11-05 Babish John G Compositions Exhibiting Inhibition Of Cyclooxygenase-2
DE102005013258B3 (de) * 2005-03-22 2006-10-12 Hopsteiner-Hallertauer Hopfenveredelungsgesellschaft M.B.H. Verfahren zur Herstellung von Naringeninderivaten aus Xanthohumol
US20080248131A1 (en) 2005-08-09 2008-10-09 Metaproteomics, Llc Protein Kinase Modulation by Hops and Acacia Products
AU2012204133B2 (en) * 2005-08-09 2013-09-19 Metaproteomics, Llc Protein kinase modulation by hops and acacia products
WO2007053915A2 (en) * 2005-11-09 2007-05-18 Universiteit Gent Naringenin derivatives with selectivity on ers
DE102006018988B3 (de) * 2006-04-25 2007-08-09 Nateco2 Gmbh & Co. Kg Verfahren zur Herstellung eines Xanthohumol-haltigen Pulvers hoher Reinheit und dessen Verwendung
EP1958628A1 (en) * 2007-02-16 2008-08-20 KAIROSmed GmbH Combination of immediately liberated drospirenone with a modified releasing formulation containing 8-prenylnaringenin for use in oral contraception and hormone replacement therapy
ATE523202T1 (de) * 2006-11-13 2011-09-15 Nookandeh Baumgaertner Aslieh Dr Extraktionsverfahren zur klassifizierten gewinnung und trennung von pflanzlichen inhaltsstoffen und deren verwendung
UA103457C2 (ru) * 2006-12-07 2013-10-25 Инбев С.А. Способ производства пива
DE102006062264A1 (de) 2006-12-22 2008-06-26 Joh. Barth & Sohn Gmbh & Co. Kg Verwendung von Xanthohumol zur Vorbeugung und/oder Bekämpfung von Lebererkrankungen
WO2008140842A1 (en) 2007-05-11 2008-11-20 Metaproteomics, Llc Methods and compositions for heavy metal detoxification
US8142821B2 (en) 2007-08-15 2012-03-27 Flazan GmbH & Co. KG Xanthohumol-enriched hop extract
CA2696311C (en) 2007-08-15 2013-07-16 Flaxan Gmbh & Co. Kg Xanthohumol-enriched hop extract
CN101574398B (zh) * 2008-05-09 2011-04-27 上海信谊百路达药业有限公司 啤酒花提取物及其制备方法与应用
CN102124432B (zh) 2008-06-20 2014-11-26 因文西斯***公司 对用于过程控制的实际和仿真设施进行交互的***和方法
FR2940089B1 (fr) * 2008-12-24 2011-03-18 Greenpharma Sas Procede de preparation d'un produit enrichi en flavonoides a partir d'un materiel vegetal
US8127060B2 (en) 2009-05-29 2012-02-28 Invensys Systems, Inc Methods and apparatus for control configuration with control objects that are fieldbus protocol-aware
US8463964B2 (en) 2009-05-29 2013-06-11 Invensys Systems, Inc. Methods and apparatus for control configuration with enhanced change-tracking
EP2392325A1 (en) 2010-06-04 2011-12-07 Universitätsklinikum Münster Compounds for the prevention and/or treatment of osteoarthrosis
CN102115772B (zh) * 2010-12-16 2012-11-14 浙江大学 微生物细胞催化异黄腐酚合成8-异戊烯基柚皮素的方法
CN102911033A (zh) * 2011-08-02 2013-02-06 苏州宝泽堂医药科技有限公司 一种从啤酒花中制备黄腐酚的方法
EP2741758B1 (en) 2011-08-08 2016-04-20 Uniwersytet Medyczny W Lodzi Polyphenolic formulation, its preparation and use
CN103371989A (zh) * 2012-04-24 2013-10-30 华东师范大学 黄腐酚在制备抑制破骨细胞分化和蚀骨功能的预防和/或治疗药物中的应用
US20150209307A1 (en) * 2012-08-10 2015-07-30 Eric Hauser Kuhrts Compositions and methods for treating mood disorders or skin disease or damage
CN103254054B (zh) * 2013-05-08 2015-03-04 浙江大学 一种具有癌症预防作用的化合物及其制备方法
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DE102013017165A1 (de) 2013-10-16 2015-04-16 Eberhard Karls Universität Tübingen Medizinische Fakultät Zusammensetzung zur Immunmodulation
CZ307451B6 (cs) * 2014-12-16 2018-09-05 Vysoká škola chemicko-technologická v Praze Způsob přípravy chmelového materiálu se zvýšeným obsahem 8-prenylnaringeninu a chmelový materiál
JP2018519342A (ja) 2015-07-02 2018-07-19 フラクサン ゲーエムベーハー ウント コー． カーゲー ホップに基づく物質およびその物質の使用
CN107337661A (zh) * 2016-11-30 2017-11-10 南昌大学 一种从啤酒花中提取8‑异戊二烯基‑4,5,7‑三羟黄烷酮的方法
US10758579B2 (en) 2016-12-07 2020-09-01 Metagreen Ventures Systems and methods for extraction of natural products
PL242648B1 (pl) * 2017-06-30 2023-04-03 Bioactive Tech Spolka Z Ograniczona Odpowiedzialnoscia Sposób otrzymywania ksantohumolu
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IL310044A (en) * 2021-07-09 2024-03-01 Innox Corp Prenylated chalcone and flavonoid compounds for use in cancer therapy
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Also Published As

Publication number Publication date
DE602004020930D1 (de) 2009-06-10
AU2004298294A1 (en) 2005-06-30
JP2007513982A (ja) 2007-05-31
PL1727555T3 (pl) 2009-10-30
RU2006125437A (ru) 2008-01-27
EP1727555B1 (en) 2009-04-29
JP5606660B2 (ja) 2014-10-15
JP2012254085A (ja) 2012-12-27
ES2326375T3 (es) 2009-10-08
UA86607C2 (ru) 2009-05-12
US20110130447A1 (en) 2011-06-02
EP1727555A1 (en) 2006-12-06
ZA200605478B (en) 2009-05-27
WO2005058336A1 (en) 2005-06-30
CA2549662A1 (en) 2005-06-30
EP1543834A1 (en) 2005-06-22
AU2004298294B2 (en) 2011-05-26
RU2370273C2 (ru) 2009-10-20
MXPA06006782A (es) 2007-01-26
CN1893963A (zh) 2007-01-10
ATE429924T1 (de) 2009-05-15
CN1893963B (zh) 2010-09-29
US20070110835A1 (en) 2007-05-17
DK1727555T3 (da) 2009-08-17
NZ548296A (en) 2009-09-25
CA2549662C (en) 2014-02-11

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