PT1601770E - Antigénios de streptococcus pyogenes - Google Patents

Antigénios de streptococcus pyogenes Download PDF

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Publication number
PT1601770E
PT1601770E PT04716233T PT04716233T PT1601770E PT 1601770 E PT1601770 E PT 1601770E PT 04716233 T PT04716233 T PT 04716233T PT 04716233 T PT04716233 T PT 04716233T PT 1601770 E PT1601770 E PT 1601770E
Authority
PT
Portugal
Prior art keywords
antigens
streptococcus pyogenes
pyogenes antigens
hyperimmune serum
serum reactive
Prior art date
Application number
PT04716233T
Other languages
English (en)
Inventor
Eszter Nagy
Andreas Meinke
Birgit Winkler
Dieter Gelbmann
Original Assignee
Intercell Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intercell Ag filed Critical Intercell Ag
Publication of PT1601770E publication Critical patent/PT1601770E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0208—Specific bacteria not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1275—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Streptococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PT04716233T 2003-03-04 2004-03-02 Antigénios de streptococcus pyogenes PT1601770E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03450061 2003-03-04

Publications (1)

Publication Number Publication Date
PT1601770E true PT1601770E (pt) 2009-12-07

Family

ID=32946995

Family Applications (1)

Application Number Title Priority Date Filing Date
PT04716233T PT1601770E (pt) 2003-03-04 2004-03-02 Antigénios de streptococcus pyogenes

Country Status (16)

Country Link
US (3) US7638136B2 (pt)
EP (8) EP2287315A1 (pt)
JP (2) JP2006520202A (pt)
CN (2) CN1756843B (pt)
AT (1) ATE441715T1 (pt)
AU (2) AU2004218284B2 (pt)
CA (1) CA2517518A1 (pt)
CY (1) CY1109683T1 (pt)
DE (1) DE602004022923D1 (pt)
DK (1) DK1601770T3 (pt)
ES (1) ES2330334T3 (pt)
HK (1) HK1084977A1 (pt)
PL (1) PL1601770T3 (pt)
PT (1) PT1601770E (pt)
SI (1) SI1601770T1 (pt)
WO (1) WO2004078907A2 (pt)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1671981A3 (en) * 2000-10-27 2006-07-05 Chiron SRL. Nucleic acids and proteins from streptococcus group A
AU2002234455C1 (en) 2001-02-21 2008-08-21 Id Biomedical Corporation Streptococcus pyogenes polypeptides and corresponding DNA fragments
AU2003260102A1 (en) * 2002-08-26 2004-03-11 Chiron Corporation Conserved and specific streptococcal genomes
PL1648500T3 (pl) 2003-07-31 2014-12-31 Novartis Vaccines & Diagnostics Inc Kompozycje immunogenne dla Streptococcus pyogenes
ITRM20030376A1 (it) 2003-07-31 2005-02-01 Univ Roma Procedimento per l'isolamento e l'espansione di cellule staminali cardiache da biopsia.
US8945589B2 (en) 2003-09-15 2015-02-03 Novartis Vaccines And Diagnostics, Srl Immunogenic compositions for Streptococcus agalactiae
EP2612679A1 (en) 2004-07-29 2013-07-10 Novartis Vaccines and Diagnostics, Inc. Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae
AU2005294275B2 (en) * 2004-10-08 2012-09-13 Glaxosmithkline Biologicals S.A. Immunogenic and therapeutic compositions for Streptococcus pyogenes
US11660317B2 (en) 2004-11-08 2023-05-30 The Johns Hopkins University Compositions comprising cardiosphere-derived cells for use in cell therapy
AU2006261342B2 (en) * 2005-06-15 2012-02-02 The Ohio State University Research Foundation Her-2 peptides
PL2325332T3 (pl) * 2005-08-26 2013-03-29 Dupont Nutrition Biosci Aps Zastosowanie genów związanych z CRISPR (genów CAS)
DK2054431T3 (da) * 2006-06-09 2012-01-02 Novartis Ag Konformere af bakterielle adhæsiner
WO2008003515A1 (en) 2006-07-07 2008-01-10 Intercell Ag Small streptococcus pyogenes antigens and their use
WO2008108830A2 (en) * 2006-10-30 2008-09-12 Novartis Ag Immunogenic and therapeutic compositions for streptococcus pyogenes
BRPI0604997A (pt) 2006-11-30 2007-05-22 Fundacao Zerbini vacina contra o estreptococo beta hemolìtico do grupo a, e respectivo processo de obtenção
GB0624874D0 (en) 2006-12-13 2007-01-24 Hansa Medical Ab Treatment
US8017337B2 (en) 2007-04-19 2011-09-13 Molecular Detection, Inc. Methods, compositions and kits for detection and analysis of antibiotic-resistant bacteria
EP2173902A4 (en) * 2007-07-03 2013-01-09 Mt Sinai Hospital THERAPEUTIC AND DIAGNOSTIC AGENTS FOR STREPTOCOCCUS OF GROUP A
AU2013203022B2 (en) * 2007-09-12 2015-09-03 Glaxosmithkline Biologicals S.A. GAS57 mutant antigens and GAS57 antibodies
CA2699513C (en) 2007-09-12 2018-03-13 Novartis Ag Gas57 mutant antigens and gas57 antibodies
CN104292312A (zh) * 2007-12-21 2015-01-21 诺华股份有限公司 链球菌溶血素o的突变形式
MX2010014355A (es) 2008-06-20 2011-03-21 Wyeth Llc Star Composiciones y procedimientos de uso de la orf 554 de cepas estreptocócicas beta-hemolíticas.
ES2648231T3 (es) * 2008-11-05 2017-12-29 Wyeth Llc Composición inmunogénica de múltiples componentes para la prevención de la enfermedad por estreptococos beta hemolíticos (EBH)
US20100234283A1 (en) 2009-02-04 2010-09-16 The Ohio State University Research Foundation Immunogenic epitopes, peptidomimetics, and anti-peptide antibodies, and methods of their use
GB0918392D0 (en) * 2009-10-20 2009-12-02 Novartis Ag Diagnostic and therapeutic methods
WO2013166281A1 (en) * 2012-05-02 2013-11-07 Cedars-Sinai Medical Center Bi-functional compositions for targeting cells to diseased tissues and methods of using same
US9845457B2 (en) 2010-04-30 2017-12-19 Cedars-Sinai Medical Center Maintenance of genomic stability in cultured stem cells
US9249392B2 (en) 2010-04-30 2016-02-02 Cedars-Sinai Medical Center Methods and compositions for maintaining genomic stability in cultured stem cells
JP2015521054A (ja) 2012-06-05 2015-07-27 カプリコール，インコーポレイテッド 心臓組織から心臓幹細胞を作製するための最適化方法および心臓治療におけるそれらの使用
WO2014028493A2 (en) 2012-08-13 2014-02-20 Cedars-Sinai Medical Center Exosomes and micro-ribonucleic acids for tissue regeneration
EP2953641A4 (en) * 2013-02-11 2016-11-16 Univ Tennessee Res Foundation GROUP-A-STREPTOKOKKEN-M RELATED PROTEINS AND METHOD OF USE
WO2016054591A1 (en) 2014-10-03 2016-04-07 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy
GB201502306D0 (en) * 2015-02-12 2015-04-01 Hansa Medical Ab Protein
US10329601B2 (en) * 2015-12-28 2019-06-25 Ionian Technologies, Inc. Nicking and extension amplification reaction (NEAR) of Streptococcus species
EP3402543B1 (en) 2016-01-11 2021-09-08 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction
US11351200B2 (en) 2016-06-03 2022-06-07 Cedars-Sinai Medical Center CDC-derived exosomes for treatment of ventricular tachyarrythmias
WO2018057542A1 (en) 2016-09-20 2018-03-29 Cedars-Sinai Medical Center Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders
EP3612191A4 (en) 2017-04-19 2020-12-30 Cedars-Sinai Medical Center METHODS AND COMPOSITIONS FOR TREATING SKELETAL MUSCLE DYSTROPHY
CN110785662A (zh) * 2017-04-26 2020-02-11 奥克兰联合服务有限公司 分析和治疗方法和组合物及其用途
EP3727351A4 (en) 2017-12-20 2021-10-06 Cedars-Sinai Medical Center MODIFIED EXTRACELLULAR VESICLES FOR IMPROVED TISSUE DELIVERY
JP2020117470A (ja) * 2019-01-25 2020-08-06 公益財団法人ヒューマンサイエンス振興財団 抗体並びに劇症型溶血性レンサ球菌感染症を予防及び／又は治療するための薬剤
CN110438261B (zh) * 2019-07-29 2022-08-12 华南农业大学 用于检测f亚群禽白血病病毒的分子标记、引物、试剂盒及应用
EP4377329A1 (en) * 2021-07-29 2024-06-05 Université de Lausanne Novel pneumococcal polypeptide antigens
CN117417427B (zh) * 2023-09-11 2024-05-07 江苏省人民医院（南京医科大学第一附属医院） 一种检测内源性自体胰岛素介导的胰岛素抗体的试剂盒

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB234771A (en) * 1924-06-02 1926-02-11 S T Leigh And Company Ltd Improved means for inserting cork discs, or the like, into caps or covers
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
EP1493825A3 (en) 1990-06-11 2005-02-09 Gilead Sciences, Inc. Method for producing nucleic acid ligands
DE10075010I2 (de) 1990-06-28 2004-01-29 Hoechst Ag Fusionsproteine mit immunglobulinanteilen, ihre Herstellung und Verwendung.
EP0591431B1 (en) * 1991-06-24 2002-12-11 Chiron Corporation Hepatitis c virus (hcv) polypeptides
DE69535036T3 (de) 1994-07-15 2011-07-07 The University of Iowa Research Foundation, IA Immunomodulatorische oligonukleotide
CZ394297A3 (cs) * 1995-06-07 1998-04-15 Biochem Vaccines Inc. Streptokokové proteiny teplotního šoku ze skupiny HSP70
CO4600681A1 (es) 1996-02-24 1998-05-08 Boehringer Ingelheim Pharma Composicion farmaceutica para la modulacion inmunitaria
AU743469C (en) 1996-08-30 2004-02-12 Rolf Bald Mirror-symmetrical selection and evolution of nucleic acids
US6958239B2 (en) 1996-11-21 2005-10-25 Oligos Etc Inc. Three component chimeric antisense oligonucleotides
US5849902A (en) 1996-09-26 1998-12-15 Oligos Etc. Inc. Three component chimeric antisense oligonucleotides
JP3515314B2 (ja) * 1997-03-25 2004-04-05 扶桑薬品工業株式会社 ストレプトコッカス・ピオゲネス菌に起因する感染症の診断用プローブ
DE19742706B4 (de) 1997-09-26 2013-07-25 Pieris Proteolab Ag Lipocalinmuteine
DE19803453A1 (de) 1998-01-30 1999-08-12 Boehringer Ingelheim Int Vakzine
NZ512574A (en) * 1998-12-23 2004-03-26 Iaf Biochem Int Novel streptococcus antigens useful as vaccines
AT408721B (de) 1999-10-01 2002-02-25 Cistem Biotechnologies Gmbh Pharmazeutische zusammensetzung enthaltend ein antigen
CA2396040A1 (en) 1999-12-30 2001-07-12 Bristol-Myers Squibb Company Novel bacterial genes and proteins that are essential for cell viability and their uses
AT409085B (de) 2000-01-28 2002-05-27 Cistem Biotechnologies Gmbh Pharmazeutische zusammensetzung zur immunmodulation und herstellung von vakzinen
JP2003531128A (ja) 2000-04-14 2003-10-21 インターツェル・アクチェンゲゼルシャフト 修飾ペプチドを含む医薬調製物
AT410173B (de) 2000-06-08 2003-02-25 Cistem Biotechnologies Gmbh Antigene zusammensetzung
HU228264B1 (en) 2000-06-08 2013-02-28 Intercell Ag Immunostimulatory oligodeoxynucleotides
AU2000279060A1 (en) 2000-07-10 2002-01-21 Telefonaktiebolaget Lm Ericsson (Publ) Resource management in uncoordinated frequency hopping system
AU2001289813B2 (en) 2000-08-17 2005-07-28 Intercell Ag A vaccine which comprises at least one antigen and a cathelididin derived antimicrobial peptide or a derivative thereof
AT410635B (de) 2000-10-18 2003-06-25 Cistem Biotechnologies Gmbh Vakzin-zusammensetzung
EP1671981A3 (en) * 2000-10-27 2006-07-05 Chiron SRL. Nucleic acids and proteins from streptococcus group A
AT410798B (de) 2001-01-26 2003-07-25 Cistem Biotechnologies Gmbh Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen
AU2002234455C1 (en) * 2001-02-21 2008-08-21 Id Biomedical Corporation Streptococcus pyogenes polypeptides and corresponding DNA fragments
AU2002306849A1 (en) * 2001-03-21 2002-10-08 Elitra Pharmaceuticals, Inc. Identification of essential genes in microorganisms
GB0107658D0 (en) * 2001-03-27 2001-05-16 Chiron Spa Streptococcus pneumoniae
JP2004533236A (ja) * 2001-04-13 2004-11-04 ワイエス 化膿性連鎖球菌（Ｓｔｒｅｐｔｏｃｏｃｃｕｓｐｙｏｇｅｎｅｓ）の表面タンパク質
KR20080081201A (ko) 2001-04-16 2008-09-08 와이어쓰 홀딩스 코포레이션 폴리펩티드 항원을 암호화하는 신규한 스트렙토코쿠스뉴모니애 개방형 판독 프레임 및 이를 포함하는 조성물
FR2824074A1 (fr) * 2001-04-26 2002-10-31 Pasteur Institut Sequence du genome streptococcus agalactiae, application au developpement de vaccins, d'outils de diagnostic, et a l'identification de cibles therapeutiques
GB0210128D0 (en) * 2002-05-02 2002-06-12 Chiron Spa Nucleic acids and proteins from streptococcus groups A & B
NZ555378A (en) * 2002-12-20 2008-10-31 Univ New Jersey Med Compositions and methods for enzymatic detachment of bacterial and fungal biofilms
PL1648500T3 (pl) * 2003-07-31 2014-12-31 Novartis Vaccines & Diagnostics Inc Kompozycje immunogenne dla Streptococcus pyogenes
WO2008003515A1 (en) * 2006-07-07 2008-01-10 Intercell Ag Small streptococcus pyogenes antigens and their use
EP2045869A1 (de) 2007-10-02 2009-04-08 Rohde & Schwarz GmbH & Co. KG Richtkoppler

Also Published As

Publication number Publication date
US8349336B2 (en) 2013-01-08
EP2287315A1 (en) 2011-02-23
EP1601770B1 (en) 2009-09-02
EP2053125B1 (en) 2014-04-30
EP2287314A1 (en) 2011-02-23
CN102512670A (zh) 2012-06-27
US7638136B2 (en) 2009-12-29
EP2287312A1 (en) 2011-02-23
HK1084977A1 (en) 2006-08-11
CN1756843A (zh) 2006-04-05
EP2287313A1 (en) 2011-02-23
JP2006520202A (ja) 2006-09-07
CN1756843B (zh) 2012-03-21
EP2290082A1 (en) 2011-03-02
US20060194751A1 (en) 2006-08-31
CA2517518A1 (en) 2004-09-16
SI1601770T1 (sl) 2010-01-29
CY1109683T1 (el) 2014-08-13
AU2009230772B2 (en) 2013-07-18
EP2287311A1 (en) 2011-02-23
US20100255034A1 (en) 2010-10-07
AU2004218284A1 (en) 2004-09-16
WO2004078907A2 (en) 2004-09-16
WO2004078907A3 (en) 2005-03-10
ATE441715T1 (de) 2009-09-15
AU2004218284B2 (en) 2009-07-23
EP1601770A2 (en) 2005-12-07
ES2330334T3 (es) 2009-12-09
PL1601770T3 (pl) 2010-02-26
JP2011015689A (ja) 2011-01-27
US20130122047A1 (en) 2013-05-16
DK1601770T3 (da) 2009-11-02
AU2009230772A1 (en) 2009-11-26
EP2053125A1 (en) 2009-04-29
DE602004022923D1 (de) 2009-10-15

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