PT1467724E - Composicao farmaceutica orodispersavel de agomelatina - Google Patents

Composicao farmaceutica orodispersavel de agomelatina

Info

Publication number: PT1467724E
Authority: PT; Portugal
Prior art keywords: orodispersavel; agomelatin; pharmaceutical composition; pharmaceutical; composition
Prior art date: 2002-01-23

Application number

PT03731733T

Other languages

English (en)

Inventor

Patrick Wuthrich

Rolland Herve

Julien Marc

Tharrault Francois

Original Assignee

Servier Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-01-23

Filing date

2003-01-22

Publication date

2006-08-31

2003-01-22 Application filed by Servier Lab filed Critical Servier Lab

2006-08-31 Publication of PT1467724E publication Critical patent/PT1467724E/pt

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

PT03731733T 2002-01-23 2003-01-22 Composicao farmaceutica orodispersavel de agomelatina PT1467724E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR0200792A FR2834890B1 (fr)	2002-01-23	2002-01-23	Composition pharmaceutique orodispersible d'agomelatine

Publications (1)

Publication Number	Publication Date
PT1467724E true PT1467724E (pt)	2006-08-31

Family

ID=27589556

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT03731733T PT1467724E (pt)	2002-01-23	2003-01-22	Composicao farmaceutica orodispersavel de agomelatina

Country Status (28)

Country	Link
US (2)	US20050131071A1 (pt)
EP (1)	EP1467724B1 (pt)
JP (2)	JP4335011B2 (pt)
KR (1)	KR100605798B1 (pt)
CN (1)	CN1287780C (pt)
AR (1)	AR038207A1 (pt)
AT (1)	ATE324882T1 (pt)
AU (1)	AU2003220786B2 (pt)
BR (1)	BRPI0307072B1 (pt)
CA (1)	CA2473201C (pt)
CY (1)	CY1105415T1 (pt)
DE (1)	DE60304993T2 (pt)
DK (1)	DK1467724T3 (pt)
EA (1)	EA007299B1 (pt)
ES (1)	ES2262999T3 (pt)
FR (1)	FR2834890B1 (pt)
GE (1)	GEP20063818B (pt)
HK (1)	HK1076742A1 (pt)
MA (1)	MA27101A1 (pt)
MX (1)	MXPA04007198A (pt)
NO (1)	NO333712B1 (pt)
NZ (1)	NZ533843A (pt)
PL (1)	PL204937B1 (pt)
PT (1)	PT1467724E (pt)
SI (1)	SI1467724T1 (pt)
UA (1)	UA77752C2 (pt)
WO (1)	WO2003061644A1 (pt)
ZA (1)	ZA200405153B (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2834889B1 (fr) *	2002-01-18	2004-04-02	Roquette Freres	Forme pharmaceutique solide orodispersible
US20030228370A1 (en) *	2002-06-11	2003-12-11	Michel Serpelloni	Orodispersible solid pharmaceutical form
AR047553A1 (es) *	2003-07-04	2006-01-25	Lundbeck & Co As H	La combinacion de un inhibidor de reabsorcion de serotonina y agomelatina
FR2884714B1 (fr) *	2005-04-20	2011-05-06	Servier Lab	Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement des troubles bipolaires
FR2890564B1 (fr) *	2005-09-09	2007-10-19	Servier Lab	Nouvelle association entre l'agomelatine et un inhibiteur de la recapture de la noradrenaline et les compositions pharmaceutiques qui la contiennent
FR2890562B1 (fr) *	2005-09-09	2012-10-12	Servier Lab	Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement des troubles du sommeil chez le patient deprime
FR2894475B1 (fr) *	2005-12-14	2008-05-16	Servier Lab	Composition pharmaceutique orodispersible pour administra- -tion oromucosale ou sublinguale d'agomelatine
CA2644905A1 (en) *	2006-03-06	2007-09-13	Teva Pharmaceutical Industries Ltd.	Ezetimibe compositions
CN101206200B (zh) *	2006-12-19	2011-12-28	北京德众万全药物技术开发有限公司	一种分离分析阿戈美拉汀中间体及其终产品的hplc方法
AU2008247805A1 (en) *	2007-05-01	2008-11-13	Concert Pharmaceuticals Inc.	Naphthyl(ethyl) acetamides
EP2359813A1 (en) *	2010-02-04	2011-08-24	Ratiopharm GmbH	Pharmaceutical composition comprising N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamid
CN101836966A (zh) *	2010-05-27	2010-09-22	北京万全阳光医药科技有限公司	一种含有阿戈美拉汀的口腔崩解片
CN102579415B (zh) *	2011-01-14	2014-11-05	成都康弘药业集团股份有限公司	一种含有阿戈美拉汀的口腔粘膜或舌下给药的药物组合物
US8426461B2 (en)	2011-01-17	2013-04-23	Takeda Pharmaceutical Company Limited	Orally dispersible tablet
BR112013017600A2 (pt)	2011-01-17	2016-10-18	Takeda Pharmaceutical	preparação para desintegração rápida, método para produzir uma preparação para desintegração rápida, preparação para absorção pela mucosa oral, método e droga para a profilaxia e / ou tratamento de um distúrbio bipolar, e, composto
WO2012130837A1 (en) *	2011-03-28	2012-10-04	Ratiopharm Gmbh	Solid agomelatine in non-crystalline form
FR2978916B1 (fr) *	2011-08-10	2013-07-26	Servier Lab	Composition pharmaceutique solide pour administration buccale d'agomelatine
EP2562151A1 (en) *	2011-08-25	2013-02-27	Dr. Reddy's Laboratories Ltd.	Processes for the preparation of agomelatine and its intermediates
JP6061924B2 (ja)	2011-10-14	2017-01-18	武田薬品工業株式会社	口腔内分散性製剤
CN103169669B (zh) *	2011-12-26	2015-06-17	中国人民解放军军事医学科学院毒物药物研究所	阿戈美拉汀包衣微丸以及可在口中分散的药物组合物
EP2872129B1 (en)	2012-07-16	2017-03-08	ratiopharm GmbH	Complex of agomelatine and cyclodextrin
CN102988315B (zh) *	2012-09-28	2017-11-17	浙江华海药业股份有限公司	阿戈美拉汀固体制剂的制备方法
FR3001894A1 (fr) *	2013-02-08	2014-08-15	Servier Lab	Composition pharmaceutique solide pour administration buccale d'agomelatine
PT2810656T (pt)	2013-06-06	2017-11-13	Zentiva As	Formulações de agomelatina compreendendo agomelatina na forma de cocristais
EP2810647A1 (en)	2013-06-06	2014-12-10	Zentiva, a.s.	Pharmaceutical formulations comprising agomelatine in the form of agomelatine co-crystal with an organic acid
CN103816129B (zh) *	2014-02-27	2020-04-28	浙江华海药业股份有限公司	阿戈美拉汀口崩片
CN104586797A (zh) *	2015-01-05	2015-05-06	万特制药(海南)有限公司	阿戈美拉汀分散片及其制备方法
CN106333929A (zh) *	2016-09-24	2017-01-18	万特制药(海南)有限公司	一种含有阿戈美拉汀的分散片及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3505433A1 (de) *	1985-02-16	1986-08-21	Basf Ag, 6700 Ludwigshafen	Direkttablettierhilfsmittel
DE3506276C1 (de) *	1985-02-22	1986-04-24	Meggle Milchindustrie Gmbh & Co Kg, 8094 Reitmehring	Direkttablettiermittel
FR2658818B1 (fr) *	1990-02-27	1993-12-31	Adir Cie	Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2710265B1 (fr) *	1993-09-22	1995-10-20	Adir	Composition pharmaceutique bioadhésive pour la libération contrôlée de principes actifs.
NZ278678A (en) *	1994-01-31	1998-03-25	Yamanouchi Pharma Co Ltd	Compressed moulded tablet with quick disintegration/dissolution in the mouth, mixture of low and high moldable saccharides as carriers
EP0906089B1 (en) *	1996-05-13	2003-08-27	Novartis Consumer Health S.A.	Buccal delivery system
US6024981A (en) *	1997-04-16	2000-02-15	Cima Labs Inc.	Rapidly dissolving robust dosage form
CA2322315C (en) *	1998-03-06	2008-09-16	Eurand International S.P.A.	Fast disintegrating tablets
JP2000273039A (ja) *	1999-01-20	2000-10-03	Taisho Pharmaceut Co Ltd	口腔内崩壊性組成物
ATE371439T1 (de) *	2000-07-27	2007-09-15	Roquette Freres	Granulat bestehend aus stärke und laktose
UA80393C2 (uk) *	2000-12-07	2007-09-25	Алтана Фарма Аг	Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
FR2834889B1 (fr) *	2002-01-18	2004-04-02	Roquette Freres	Forme pharmaceutique solide orodispersible

2002
- 2002-01-23 FR FR0200792A patent/FR2834890B1/fr not_active Expired - Fee Related
2003
- 2003-01-22 BR BRPI0307072A patent/BRPI0307072B1/pt not_active IP Right Cessation
- 2003-01-22 SI SI200330266T patent/SI1467724T1/sl unknown
- 2003-01-22 EA EA200400928A patent/EA007299B1/ru not_active IP Right Cessation
- 2003-01-22 KR KR1020047011351A patent/KR100605798B1/ko not_active IP Right Cessation
- 2003-01-22 PL PL370160A patent/PL204937B1/pl unknown
- 2003-01-22 DK DK03731733T patent/DK1467724T3/da active
- 2003-01-22 CN CNB038027100A patent/CN1287780C/zh not_active Expired - Fee Related
- 2003-01-22 JP JP2003561589A patent/JP4335011B2/ja not_active Expired - Fee Related
- 2003-01-22 EP EP03731733A patent/EP1467724B1/fr not_active Expired - Lifetime
- 2003-01-22 US US10/502,593 patent/US20050131071A1/en not_active Abandoned
- 2003-01-22 GE GE5625A patent/GEP20063818B/en unknown
- 2003-01-22 WO PCT/FR2003/000197 patent/WO2003061644A1/fr active IP Right Grant
- 2003-01-22 AU AU2003220786A patent/AU2003220786B2/en not_active Ceased
- 2003-01-22 CA CA2473201A patent/CA2473201C/fr not_active Expired - Fee Related
- 2003-01-22 AR ARP030100178A patent/AR038207A1/es unknown
- 2003-01-22 DE DE60304993T patent/DE60304993T2/de not_active Expired - Lifetime
- 2003-01-22 PT PT03731733T patent/PT1467724E/pt unknown
- 2003-01-22 NZ NZ533843A patent/NZ533843A/en not_active IP Right Cessation
- 2003-01-22 AT AT03731733T patent/ATE324882T1/de active
- 2003-01-22 MX MXPA04007198A patent/MXPA04007198A/es active IP Right Grant
- 2003-01-22 ES ES03731733T patent/ES2262999T3/es not_active Expired - Lifetime
- 2003-01-22 UA UA20040806965A patent/UA77752C2/uk unknown
2004
- 2004-06-28 ZA ZA2004/05153A patent/ZA200405153B/en unknown
- 2004-07-12 MA MA27775A patent/MA27101A1/fr unknown
- 2004-08-18 NO NO20043441A patent/NO333712B1/no not_active IP Right Cessation
2005
- 2005-10-10 HK HK05108935A patent/HK1076742A1/xx not_active IP Right Cessation
2006
- 2006-06-30 CY CY20061100898T patent/CY1105415T1/el unknown
2009
- 2009-01-20 JP JP2009010024A patent/JP2009137994A/ja active Pending
2010
- 2010-06-22 US US12/803,250 patent/US20100260840A1/en not_active Abandoned

Also Published As

Publication number	Publication date
DE60304993D1 (de)	2006-06-08
JP2009137994A (ja)	2009-06-25
JP2005523253A (ja)	2005-08-04
EA007299B1 (ru)	2006-08-25
WO2003061644A1 (fr)	2003-07-31
UA77752C2 (uk)	2007-01-15
BR0307072A (pt)	2004-12-28
MA27101A1 (fr)	2004-12-20
EP1467724B1 (fr)	2006-05-03
ES2262999T3 (es)	2006-12-01
PL204937B1 (pl)	2010-02-26
NO20043441L (no)	2004-08-18
KR20040075102A (ko)	2004-08-26
JP4335011B2 (ja)	2009-09-30
CN1622804A (zh)	2005-06-01
CY1105415T1 (el)	2010-04-28
DE60304993T2 (de)	2007-01-18
NZ533843A (en)	2005-08-26
AR038207A1 (es)	2005-01-05
ZA200405153B (en)	2005-08-31
SI1467724T1 (sl)	2006-08-31
NO333712B1 (no)	2013-09-02
US20100260840A1 (en)	2010-10-14
MXPA04007198A (es)	2004-10-29
AU2003220786B2 (en)	2007-08-02
GEP20063818B (en)	2006-05-10
CA2473201C (fr)	2010-08-17
HK1076742A1 (en)	2006-01-27
KR100605798B1 (ko)	2006-08-01
FR2834890A1 (fr)	2003-07-25
EP1467724A1 (fr)	2004-10-20
EA200400928A1 (ru)	2004-12-30
FR2834890B1 (fr)	2004-02-27
CN1287780C (zh)	2006-12-06
DK1467724T3 (da)	2006-08-28
PL370160A1 (en)	2005-05-16
US20050131071A1 (en)	2005-06-16
BRPI0307072B1 (pt)	2017-05-02
ATE324882T1 (de)	2006-06-15
CA2473201A1 (fr)	2003-07-31

Publication	Publication Date	Title
PT1467724E (pt)	2006-08-31	Composicao farmaceutica orodispersavel de agomelatina
FI20011478A (fi)	2003-01-06	Farmaseuttinen koostumus
PT1501534E (pt)	2006-09-29	Formulacoes farmaceuticas
AU2003291103A8 (en)	2004-06-15	Pharmaceutical composition
DE10393374D2 (de)	2005-09-01	Zusammensetzung
DK1587478T3 (da)	2013-10-21	Farmaceutisk sammensætning
SE0500163L (sv)	2005-01-24	Sammansättning
EP1425019A4 (en)	2004-11-17	PHARMACEUTICAL COMPOSITION
AU2003250372A8 (en)	2004-01-06	Pharmaceutical composition
IS7051A (is)	2003-11-26	Lyfjasamsetningar
DK1561472T3 (da)	2013-11-11	Faststofsammensætning
PT1558263E (pt)	2006-10-31	Composicao farmaceutica de libertacao prolongada
FI20022128A (fi)	2003-06-06	Farmaseuttinen koostumus
IS7581A (is)	2004-12-03	Lyfjasamsetning
NO20034952D0 (no)	2003-11-06	Farmasöytiske forbindelser
NO20044140D0 (no)	2004-09-29	New Composition
NO20044164L (no)	2004-09-30	Farmasoytiske sammensetninger
DOP2002000508A (es)	2003-06-15	Composición farmaceutica
DE112004001429D2 (de)	2006-04-13	Pharmazeutischer Wirkstoff
ITMI20020926A1 (it)	2003-10-30	Composizioni farmaceutiche riepitelizzanti
FI5468U1 (fi)	2002-07-30	Farmaseuttinen koostumus
GB0217703D0 (en)	2002-09-11	Pharmaceutical composition
ITMI20030705A1 (it)	2004-10-10	Composizione farmaceutica contenente n-acetil-l-cisteina
DE602004030921D1 (de)	2011-02-17	Pharmazeutische zusammensetzung
SE0201660D0 (sv)	2002-05-31	Pharmaceutical formulation