PT1246825E - Compostos pirrolicos condensados agentes farmaceuticos contendo os mesmos e seu uso - Google Patents

Compostos pirrolicos condensados agentes farmaceuticos contendo os mesmos e seu uso

Info

Publication number
PT1246825E
PT1246825E PT01902310T PT01902310T PT1246825E PT 1246825 E PT1246825 E PT 1246825E PT 01902310 T PT01902310 T PT 01902310T PT 01902310 T PT01902310 T PT 01902310T PT 1246825 E PT1246825 E PT 1246825E
Authority
PT
Portugal
Prior art keywords
condensed
compounds
same
pharmaceutical agents
agents containing
Prior art date
Application number
PT01902310T
Other languages
English (en)
Inventor
Stefan Laufer
Hans-Gunter Striegel
Karola Tollmann
Susanne Tries
Original Assignee
Merckle Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merckle Gmbh filed Critical Merckle Gmbh
Publication of PT1246825E publication Critical patent/PT1246825E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
PT01902310T 2000-01-13 2001-01-12 Compostos pirrolicos condensados agentes farmaceuticos contendo os mesmos e seu uso PT1246825E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10001166A DE10001166A1 (de) 2000-01-13 2000-01-13 Anellierte Pyrrolverbindungen, diese enthaltende pharmazeutische Mittel und deren Verwendung

Publications (1)

Publication Number Publication Date
PT1246825E true PT1246825E (pt) 2004-04-30

Family

ID=7627401

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01902310T PT1246825E (pt) 2000-01-13 2001-01-12 Compostos pirrolicos condensados agentes farmaceuticos contendo os mesmos e seu uso

Country Status (16)

Country Link
US (1) US6936632B2 (pt)
EP (1) EP1246825B1 (pt)
JP (1) JP2003525875A (pt)
KR (1) KR20020081254A (pt)
CN (1) CN1191254C (pt)
AT (1) ATE256685T1 (pt)
AU (1) AU2001230180A1 (pt)
CA (1) CA2396413A1 (pt)
DE (2) DE10001166A1 (pt)
DK (1) DK1246825T3 (pt)
ES (1) ES2213102T3 (pt)
MX (1) MXPA02006863A (pt)
NO (1) NO323238B1 (pt)
PT (1) PT1246825E (pt)
TR (1) TR200400270T4 (pt)
WO (1) WO2001051491A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10004157A1 (de) 2000-02-01 2001-08-02 Merckle Gmbh Chem Pharm Fabrik 4-Pyridyl-und 2,4-Pyrimidinyl-substituierte Pyrrolderivate und ihre Anwendung in der Pharmazie
BR0212244A (pt) 2001-08-30 2004-10-05 Merckle Gmbh Uso de um ou mais do que um composto e seus isÈmeros ópticos, derivados e sais fisiologicamente aceitáveis, composição farmacêutica, e, método de tratamento ou de prevenção da degeneração ou da destruição de cartilagem articular e/ou de osso subcondral em uma ou mais articulações de um mamìfero
US20070077297A1 (en) 2004-09-30 2007-04-05 Scolr Pharma, Inc. Modified release ibuprofen dosage form
US20060068009A1 (en) * 2004-09-30 2006-03-30 Scolr Pharma, Inc. Modified release ibuprofen dosage form
US7749537B2 (en) * 2006-12-04 2010-07-06 Scolr Pharma, Inc. Method of forming a tablet
US20190060286A1 (en) 2016-02-29 2019-02-28 University Of Florida Research Foundation, Incorpo Chemotherapeutic Methods

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4232038A (en) * 1979-08-31 1980-11-04 Syntex (U.S.A.) Inc. 5-Alkylsulfinylbenzoyl- and 5-alkylsulfonylbenzoyl-1,2-dihydro-3H-pyrrolo[1,]pyrrole-1-carboxylic acids
ATE17480T1 (de) 1982-03-03 1986-02-15 Du Pont Entzuendungshemmende und/oder schmerzstillende 2,3-diaryl-5-halo thiophene.
US5260451A (en) * 1989-05-11 1993-11-09 Merckle Gmbh Substituted pyrrole compounds and use thereof in pharmaceutical compositions
WO1994015932A1 (en) 1993-01-15 1994-07-21 G.D. Searle & Co. Novel 3,4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents
US5380738A (en) 1993-05-21 1995-01-10 Monsanto Company 2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents
US5474995A (en) 1993-06-24 1995-12-12 Merck Frosst Canada, Inc. Phenyl heterocycles as cox-2 inhibitors
US5344991A (en) 1993-10-29 1994-09-06 G.D. Searle & Co. 1,2 diarylcyclopentenyl compounds for the treatment of inflammation
US5475018A (en) 1993-11-30 1995-12-12 G. D. Searle & Co. 1,5-diphenyl pyrazole compounds for treatment of inflammation
DE69509223T2 (de) 1994-02-10 1999-09-16 Searle & Co Substituierte spiroverbindungen zur behandlung von entzündungen
US5418254A (en) 1994-05-04 1995-05-23 G. D. Searle & Co. Substituted cyclopentadienyl compounds for the treatment of inflammation
DE4419247A1 (de) * 1994-06-01 1995-12-07 Merckle Gmbh Sulfonylierte Pyrrolizincarbonsäureamide und deren Anwendung in der Pharmazie
DE4419246A1 (de) * 1994-06-01 1995-12-07 Merckle Gmbh Heteroarylsubstituierte Pyrrolizinverbindungen und deren Anwendung in der Pharmazie
DE4419315A1 (de) * 1994-06-01 1995-12-07 Merckle Gmbh Heteropyrrolizinverbindungen und deren Anwendung in der Pharmazie
US5593994A (en) 1994-09-29 1997-01-14 The Dupont Merck Pharmaceutical Company Prostaglandin synthase inhibitors
DE69635048T2 (de) * 1995-06-12 2006-02-16 G.D. Searle & Co. Mittel, enthaltend einen cyclooxygenase-2 inhibitor und einen 5-lipoxygenase inhibitor
DE19624290A1 (de) 1996-06-18 1998-01-02 Merckle Gmbh Verwendungen von Pyrrolizin-Verbindungen in der Pharmazie
DE19624289A1 (de) * 1996-06-18 1998-01-02 Merckle Gmbh Pyrrolizin-Verbindungen und deren Verwendung
AU3953899A (en) * 1998-05-27 1999-12-13 Nippon Shinyaku Co. Ltd. Cyclooxygenase-2 inhibitors
DE19845446A1 (de) 1998-10-02 2000-04-06 Merckle Gmbh Antiinflammatorische Oxo- und Hydroxyderivate von Pyrrolizinen und deren Verwendung in der Pharmazie
US6878738B1 (en) 1999-11-23 2005-04-12 Merckle Gmbh Anti-inflammatory oxo derivatives and hydroxy derivatives of pyrrolizines, and their pharmaceutical use
DE10004157A1 (de) 2000-02-01 2001-08-02 Merckle Gmbh Chem Pharm Fabrik 4-Pyridyl-und 2,4-Pyrimidinyl-substituierte Pyrrolderivate und ihre Anwendung in der Pharmazie

Also Published As

Publication number Publication date
MXPA02006863A (es) 2004-04-05
ATE256685T1 (de) 2004-01-15
AU2001230180A1 (en) 2001-07-24
WO2001051491A1 (de) 2001-07-19
NO323238B1 (no) 2007-02-05
KR20020081254A (ko) 2002-10-26
DE50101187D1 (de) 2004-01-29
DK1246825T3 (da) 2004-04-13
CN1418217A (zh) 2003-05-14
DE10001166A1 (de) 2001-07-19
EP1246825B1 (de) 2003-12-17
CN1191254C (zh) 2005-03-02
JP2003525875A (ja) 2003-09-02
EP1246825A1 (de) 2002-10-09
US6936632B2 (en) 2005-08-30
US20040122002A1 (en) 2004-06-24
CA2396413A1 (en) 2001-07-19
TR200400270T4 (tr) 2004-03-22
ES2213102T3 (es) 2004-08-16
NO20023363L (no) 2002-09-10
NO20023363D0 (no) 2002-07-12

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