PT1140018E - Suspensoes de poliol/oleo para a libertacao sustentada de proteinas - Google Patents
Suspensoes de poliol/oleo para a libertacao sustentada de proteinasInfo
- Publication number
- PT1140018E PT1140018E PT99968164T PT99968164T PT1140018E PT 1140018 E PT1140018 E PT 1140018E PT 99968164 T PT99968164 T PT 99968164T PT 99968164 T PT99968164 T PT 99968164T PT 1140018 E PT1140018 E PT 1140018E
- Authority
- PT
- Portugal
- Prior art keywords
- polyol
- oil suspensions
- liberation
- protein
- sustained protein
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/221,181 US6245740B1 (en) | 1998-12-23 | 1998-12-23 | Polyol:oil suspensions for the sustained release of proteins |
| US44820599A | 1999-11-23 | 1999-11-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1140018E true PT1140018E (pt) | 2004-02-27 |
Family
ID=26915566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99968164T PT1140018E (pt) | 1998-12-23 | 1999-12-20 | Suspensoes de poliol/oleo para a libertacao sustentada de proteinas |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1140018B1 (pt) |
| JP (1) | JP2002533378A (pt) |
| KR (1) | KR100491815B1 (pt) |
| CN (1) | CN1158068C (pt) |
| AT (1) | ATE251448T1 (pt) |
| AU (1) | AU769610B2 (pt) |
| CA (1) | CA2355618C (pt) |
| DE (1) | DE69911993T2 (pt) |
| DK (1) | DK1140018T3 (pt) |
| ES (1) | ES2204187T3 (pt) |
| HU (1) | HUP0104756A3 (pt) |
| IL (2) | IL143706A0 (pt) |
| PT (1) | PT1140018E (pt) |
| SI (1) | SI1140018T1 (pt) |
| TW (1) | TWI221777B (pt) |
| WO (1) | WO2000038652A1 (pt) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7022674B2 (en) | 1999-12-16 | 2006-04-04 | Eli Lilly And Company | Polypeptide compositions with improved stability |
| ES2253375T3 (es) | 2000-04-19 | 2006-06-01 | Genentech, Inc. | Formulaciones de liberacion sostenida. |
| BR0115392A (pt) | 2000-11-03 | 2004-06-15 | Biomedicines Inc | Método para o tratamento de uma doença sensìvel a interferona em um animal de sangue quente, método para individualizar as dosagens de uma interferona no tratamento, método para a fabricação de um dispositivo de liberação de efeito terapêutico de longa duração de uma droga ao longo de um perìodo de tempo, e conjunto útil para a ministração de uma quantidade relativamente constante de uma droga |
| IL159048A0 (en) | 2001-06-21 | 2004-05-12 | Genentech Inc | Sustained release formulation |
| US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
| FR2868704B1 (fr) * | 2004-04-07 | 2007-09-14 | Ethypharm Sa | Utilisation de lipides pour ameliorer la biodisponibilite de principes actifs proteiques en formulations injectables sous cutanees ou intra-musculaires |
| US7772182B2 (en) * | 2004-08-05 | 2010-08-10 | Alza Corporation | Stable suspension formulations of erythropoietin receptor agonists |
| WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
| US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
| US8008453B2 (en) | 2005-08-12 | 2011-08-30 | Amgen Inc. | Modified Fc molecules |
| EP2020990B1 (en) | 2006-05-30 | 2010-09-22 | Intarcia Therapeutics, Inc | Two-piece, internal-channel osmotic delivery system flow modulator |
| AU2007284759B2 (en) | 2006-08-09 | 2010-10-28 | Intarcia Therapeutics, Inc. | Osmotic delivery systems and piston assemblies |
| US7825093B2 (en) | 2006-10-25 | 2010-11-02 | Amgen Inc. | Methods of using OSK1 peptide analogs |
| US8309138B2 (en) | 2007-02-16 | 2012-11-13 | Aska Pharmaceutical Co., Ltd. | Pharmaceutical composition comprising microparticle oily suspension |
| US20080227805A1 (en) | 2007-02-28 | 2008-09-18 | Abbott Laboratories | Sustained release parenteral formulations of buprenorphine |
| AU2008244523B2 (en) | 2007-04-23 | 2012-02-16 | Intarcia Therapeutics, Inc. | Suspension formulations of insulinotropic peptides and uses thereof |
| JP5591691B2 (ja) | 2007-05-22 | 2014-09-17 | アムジエン・インコーポレーテツド | 生物活性を有する融合タンパク質を作製するための組成物及び方法 |
| EP2240155B1 (en) | 2008-02-13 | 2012-06-06 | Intarcia Therapeutics, Inc | Devices, formulations, and methods for delivery of multiple beneficial agents |
| RU2547990C2 (ru) | 2009-09-28 | 2015-04-10 | Интарсия Терапьютикс, Инк. | Быстрое достижение и/или прекращение существенной стабильной доставки лекарственного средства |
| US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
| US9340590B2 (en) | 2011-03-16 | 2016-05-17 | Amgen Inc. | Potent and selective inhibitors of NaV1.3 and NaV1.7 |
| WO2014099984A1 (en) | 2012-12-20 | 2014-06-26 | Amgen Inc. | Apj receptor agonists and uses thereof |
| US10344060B2 (en) | 2013-03-12 | 2019-07-09 | Amgen Inc. | Potent and selective inhibitors of Nav1.7 |
| AU2015274574B2 (en) | 2014-06-10 | 2019-10-10 | Amgen Inc. | Apelin polypeptides |
| US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
| EP3302354B1 (en) | 2015-06-03 | 2023-10-04 | i2o Therapeutics, Inc. | Implant placement systems |
| RU2760007C2 (ru) | 2016-05-16 | 2021-11-22 | Интарсия Терапьютикс, Инк. | Полипептиды, селективные к рецепторам глюкагона, и способы их применения |
| USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
| USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
| WO2018129058A1 (en) | 2017-01-03 | 2018-07-12 | Intarcia Therapeutics, Inc. | Methods comprising continuous administration of a glp-1 receptor agonist and co-adminstration of a drug |
| US11318190B2 (en) | 2017-05-05 | 2022-05-03 | United States Government As Represented By The Department Of Veterans Affairs | Methods and compositions for treating liver disease |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61500439A (ja) * | 1983-11-21 | 1986-03-13 | リ−ジエンツ オヴ ザ ユニヴア−シテイ− オヴ ミネソタ | 慢性的非経口ホルモン投与用緩衝化ポリオ−ル−ホルモン混合物 |
| US5411951A (en) * | 1984-10-04 | 1995-05-02 | Monsanto Company | Prolonged release of biologically active somatotropin |
| EP0374120A3 (en) * | 1988-12-13 | 1991-07-31 | Monsanto Company | Comosition for controlled release of polypeptides |
| US5114929A (en) * | 1989-03-21 | 1992-05-19 | Beecham Group P.L.C. | Pharmaceutical formulation |
| US6004549A (en) * | 1994-12-14 | 1999-12-21 | Schering Corporation | Crystalline protein controlled release compositions |
-
1999
- 1999-12-20 WO PCT/US1999/030527 patent/WO2000038652A1/en active IP Right Grant
- 1999-12-20 EP EP99968164A patent/EP1140018B1/en not_active Expired - Lifetime
- 1999-12-20 ES ES99968164T patent/ES2204187T3/es not_active Expired - Lifetime
- 1999-12-20 IL IL14370699A patent/IL143706A0/xx active IP Right Grant
- 1999-12-20 KR KR10-2001-7007843A patent/KR100491815B1/ko not_active IP Right Cessation
- 1999-12-20 CA CA002355618A patent/CA2355618C/en not_active Expired - Fee Related
- 1999-12-20 DK DK99968164T patent/DK1140018T3/da active
- 1999-12-20 JP JP2000590606A patent/JP2002533378A/ja not_active Withdrawn
- 1999-12-20 HU HU0104756A patent/HUP0104756A3/hu unknown
- 1999-12-20 CN CNB99816271XA patent/CN1158068C/zh not_active Expired - Fee Related
- 1999-12-20 DE DE69911993T patent/DE69911993T2/de not_active Expired - Fee Related
- 1999-12-20 AU AU24838/00A patent/AU769610B2/en not_active Ceased
- 1999-12-20 AT AT99968164T patent/ATE251448T1/de not_active IP Right Cessation
- 1999-12-20 PT PT99968164T patent/PT1140018E/pt unknown
- 1999-12-20 SI SI9930434T patent/SI1140018T1/xx unknown
- 1999-12-21 TW TW088122540A patent/TWI221777B/zh active
-
2001
- 2001-06-12 IL IL143706A patent/IL143706A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0104756A3 (en) | 2006-04-28 |
| DE69911993D1 (de) | 2003-11-13 |
| CA2355618A1 (en) | 2000-07-06 |
| CN1158068C (zh) | 2004-07-21 |
| EP1140018A1 (en) | 2001-10-10 |
| IL143706A0 (en) | 2002-04-21 |
| DE69911993T2 (de) | 2004-05-19 |
| TWI221777B (en) | 2004-10-11 |
| ATE251448T1 (de) | 2003-10-15 |
| JP2002533378A (ja) | 2002-10-08 |
| AU2483800A (en) | 2000-07-31 |
| CN1335765A (zh) | 2002-02-13 |
| EP1140018B1 (en) | 2003-10-08 |
| ES2204187T3 (es) | 2004-04-16 |
| HUP0104756A2 (hu) | 2002-04-29 |
| DK1140018T3 (da) | 2004-02-02 |
| CA2355618C (en) | 2007-03-13 |
| KR20010099864A (ko) | 2001-11-09 |
| KR100491815B1 (ko) | 2005-05-27 |
| AU769610B2 (en) | 2004-01-29 |
| IL143706A (en) | 2008-04-13 |
| SI1140018T1 (en) | 2003-12-31 |
| WO2000038652A1 (en) | 2000-07-06 |
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