PT1104415E - Metodo de preparacao de nucleosidos de 1,3-oxatiolano - Google Patents

Metodo de preparacao de nucleosidos de 1,3-oxatiolano

Info

Publication number: PT1104415E
Authority: PT; Portugal
Prior art keywords: preparation; nucleosides; oxatiolane; oxathiolane; processes
Prior art date: 1998-08-12

Application number

PT99943712T

Other languages

English (en)

Inventor

Dennis C Liotta

George R Painter

Almond Merrick

Cleary Darryl

Soria Jose

Sznaidman Marcos Luis

Original Assignee

Univ Emory

Gilead Sciences Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-08-12

Filing date

1999-08-12

Publication date

2005-03-31

1999-08-12 Application filed by Univ Emory, Gilead Sciences Inc filed Critical Univ Emory

2005-03-31 Publication of PT1104415E publication Critical patent/PT1104415E/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
- C07D327/04—Five-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D411/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

PT99943712T 1998-08-12 1999-08-12 Metodo de preparacao de nucleosidos de 1,3-oxatiolano PT1104415E (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US9621498P	1998-08-12	1998-08-12
US12284199P	1999-03-04	1999-03-04

Publications (1)

Publication Number	Publication Date
PT1104415E true PT1104415E (pt)	2005-03-31

Family

ID=26791450

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PT99943712T PT1104415E (pt)	1998-08-12	1999-08-12	Metodo de preparacao de nucleosidos de 1,3-oxatiolano
PT101816783T PT2322518E (pt)	1998-08-12	1999-08-12	Métodos de fabrico de nucleosídeos de 1,3-dioxolano e 1,3 oxatiolano

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PT101816783T PT2322518E (pt)	1998-08-12	1999-08-12	Métodos de fabrico de nucleosídeos de 1,3-dioxolano e 1,3 oxatiolano

Country Status (17)

Country	Link
US (4)	US6215004B1 (pt)
EP (4)	EP1104415B1 (pt)
JP (4)	JP4249393B2 (pt)
KR (3)	KR100687194B1 (pt)
CN (1)	CN1141305C (pt)
AT (2)	ATE282034T1 (pt)
AU (2)	AU771779B2 (pt)
BR (1)	BR9912951B1 (pt)
CA (3)	CA2714085C (pt)
DE (2)	DE69921829T2 (pt)
ES (2)	ES2537540T3 (pt)
HK (2)	HK1038921A1 (pt)
IL (4)	IL141359A0 (pt)
MX (1)	MXPA01001552A (pt)
PT (2)	PT1104415E (pt)
RU (2)	RU2244712C2 (pt)
WO (1)	WO2000009494A1 (pt)

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WO2011141805A2 (en)	2010-05-14	2011-11-17	Lupin Limited	An improved process for the manufacture of lamivudine
EP2739620A1 (en)	2011-08-05	2014-06-11	Lupin Limited	A stereoselective process for preparation of 1,3-oxathiolane nucleosides
CN106478618A (zh) *	2016-10-14	2017-03-08	上海礼泰医药科技有限公司	恩曲他滨氢卤酸盐的制备方法
CN109553610B (zh) *	2018-12-21	2020-10-27	江西富祥药业股份有限公司	一种恩曲他滨异构体的制备方法
CN115043823A (zh) *	2022-06-28	2022-09-13	江苏普信制药有限公司	一种恩曲他滨的合成方法

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1999
- 1999-08-12 CN CNB998099929A patent/CN1141305C/zh not_active Expired - Lifetime
- 1999-08-12 PT PT99943712T patent/PT1104415E/pt unknown
- 1999-08-12 CA CA2714085A patent/CA2714085C/en not_active Expired - Lifetime
- 1999-08-12 KR KR1020017001827A patent/KR100687194B1/ko not_active IP Right Cessation
- 1999-08-12 AT AT99943712T patent/ATE282034T1/de active
- 1999-08-12 MX MXPA01001552A patent/MXPA01001552A/es not_active IP Right Cessation
- 1999-08-12 RU RU2001106606/04A patent/RU2244712C2/ru active
- 1999-08-12 US US09/373,891 patent/US6215004B1/en not_active Expired - Lifetime
- 1999-08-12 BR BRPI9912951-5A patent/BR9912951B1/pt not_active IP Right Cessation
- 1999-08-12 WO PCT/US1999/018584 patent/WO2000009494A1/en active Application Filing
- 1999-08-12 KR KR1020067007631A patent/KR100856416B1/ko not_active IP Right Cessation
- 1999-08-12 EP EP99943712A patent/EP1104415B1/en not_active Expired - Lifetime
- 1999-08-12 EP EP10181678.3A patent/EP2322518B1/en not_active Expired - Lifetime
- 1999-08-12 CA CA2563022A patent/CA2563022C/en not_active Expired - Lifetime
- 1999-08-12 RU RU2004125183/04A patent/RU2439069C2/ru not_active Application Discontinuation
- 1999-08-12 IL IL14135999A patent/IL141359A0/xx active IP Right Grant
- 1999-08-12 AT AT03077251T patent/ATE292631T1/de not_active IP Right Cessation
- 1999-08-12 EP EP03077251A patent/EP1361223B1/en not_active Expired - Lifetime
- 1999-08-12 ES ES10181678.3T patent/ES2537540T3/es not_active Expired - Lifetime
- 1999-08-12 AU AU56752/99A patent/AU771779B2/en not_active Expired
- 1999-08-12 EP EP05075522A patent/EP1535921A1/en not_active Ceased
- 1999-08-12 KR KR1020077019476A patent/KR101208429B1/ko not_active IP Right Cessation
- 1999-08-12 DE DE69921829T patent/DE69921829T2/de not_active Expired - Lifetime
- 1999-08-12 PT PT101816783T patent/PT2322518E/pt unknown
- 1999-08-12 DE DE69924651T patent/DE69924651D1/de not_active Expired - Lifetime
- 1999-08-12 JP JP2000564946A patent/JP4249393B2/ja not_active Expired - Fee Related
- 1999-08-12 CA CA002340214A patent/CA2340214C/en not_active Expired - Lifetime
- 1999-08-12 ES ES99943712T patent/ES2232169T3/es not_active Expired - Lifetime
2000
- 2000-05-15 US US09/570,885 patent/US6518425B1/en not_active Expired - Lifetime
- 2000-09-26 US US09/669,806 patent/US6576776B1/en not_active Expired - Lifetime
2001
- 2001-02-09 IL IL141359A patent/IL141359A/en not_active IP Right Cessation
2002
- 2002-01-21 HK HK02100476A patent/HK1038921A1/xx not_active IP Right Cessation
2003
- 2003-02-11 US US10/361,980 patent/US6939965B2/en not_active Expired - Lifetime
2004
- 2004-06-30 AU AU2004202930A patent/AU2004202930C1/en not_active Expired
2006
- 2006-02-15 IL IL173745A patent/IL173745A/en not_active IP Right Cessation
2008
- 2008-11-13 JP JP2008291234A patent/JP5203897B2/ja not_active Expired - Fee Related
2009
- 2009-10-01 IL IL201293A patent/IL201293A/en not_active IP Right Cessation
2011
- 2011-10-11 HK HK11110762.2A patent/HK1156604A1/xx not_active IP Right Cessation
2012
- 2012-05-18 JP JP2012114415A patent/JP5547772B2/ja not_active Expired - Fee Related
2014
- 2014-03-25 JP JP2014061275A patent/JP5956492B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
KR100687194B1 (ko)	2007-02-27
CA2340214A1 (en)	2000-02-24
US6518425B1 (en)	2003-02-11
EP1535921A1 (en)	2005-06-01
DE69921829T2 (de)	2005-10-27
US6576776B1 (en)	2003-06-10
IL173745A (en)	2010-05-31
RU2439069C2 (ru)	2012-01-10
JP2009108080A (ja)	2009-05-21
ES2232169T3 (es)	2005-05-16
RU2004125183A (ru)	2006-01-27
IL141359A0 (en)	2002-03-10
HK1038921A1 (en)	2002-04-04
CA2714085C (en)	2013-02-05
ES2537540T3 (es)	2015-06-09
DE69924651D1 (de)	2005-05-12
JP2012176974A (ja)	2012-09-13
PT2322518E (pt)	2015-06-08
KR20060063991A (ko)	2006-06-12
CA2340214C (en)	2007-10-30
JP5547772B2 (ja)	2014-07-16
CA2563022C (en)	2010-11-23
US6939965B2 (en)	2005-09-06
JP2002522534A (ja)	2002-07-23
KR20070094667A (ko)	2007-09-20
IL141359A (en)	2006-07-05
KR100856416B1 (ko)	2008-09-04
CN1141305C (zh)	2004-03-10
EP1361223B1 (en)	2005-04-06
EP2322518A1 (en)	2011-05-18
WO2000009494A1 (en)	2000-02-24
US6215004B1 (en)	2001-04-10
EP2322518B1 (en)	2015-02-25
JP5203897B2 (ja)	2013-06-05
US20030144532A1 (en)	2003-07-31
AU2004202930C1 (en)	2008-11-13
CA2563022A1 (en)	2000-02-24
KR101208429B1 (ko)	2012-12-05
ATE282034T1 (de)	2004-11-15
EP1104415B1 (en)	2004-11-10
BR9912951A (pt)	2001-10-02
CN1313858A (zh)	2001-09-19
IL173745A0 (en)	2006-07-05
KR20010072428A (ko)	2001-07-31
AU2004202930A1 (en)	2004-07-29
AU5675299A (en)	2000-03-06
MXPA01001552A (es)	2004-08-23
IL201293A (en)	2011-02-28
EP1361223A1 (en)	2003-11-12
RU2244712C2 (ru)	2005-01-20
JP4249393B2 (ja)	2009-04-02
HK1156604A1 (en)	2012-06-15
BR9912951B1 (pt)	2012-01-10
IL201293A0 (en)	2010-05-31
ATE292631T1 (de)	2005-04-15
JP2014132026A (ja)	2014-07-17
DE69921829D1 (de)	2004-12-16
JP5956492B2 (ja)	2016-07-27
AU771779B2 (en)	2004-04-01
AU2004202930B2 (en)	2008-05-08
EP1104415A1 (en)	2001-06-06
CA2714085A1 (en)	2000-02-24

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