PT1047450E - Combinacoes inibidor ace - inibidor mmp - Google Patents

Combinacoes inibidor ace - inibidor mmp

Info

Publication number
PT1047450E
PT1047450E PT98959416T PT98959416T PT1047450E PT 1047450 E PT1047450 E PT 1047450E PT 98959416 T PT98959416 T PT 98959416T PT 98959416 T PT98959416 T PT 98959416T PT 1047450 E PT1047450 E PT 1047450E
Authority
PT
Portugal
Prior art keywords
inhibitor
combinations
mmp
ace
ace inhibitor
Prior art date
Application number
PT98959416T
Other languages
English (en)
Inventor
Joseph Thomas Peterson Jr
Milton Lethan Pressler
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22083543&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1047450(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of PT1047450E publication Critical patent/PT1047450E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/556Angiotensin converting enzyme inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
PT98959416T 1997-12-23 1998-11-10 Combinacoes inibidor ace - inibidor mmp PT1047450E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6859497P 1997-12-23 1997-12-23

Publications (1)

Publication Number Publication Date
PT1047450E true PT1047450E (pt) 2003-02-28

Family

ID=22083543

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98959416T PT1047450E (pt) 1997-12-23 1998-11-10 Combinacoes inibidor ace - inibidor mmp

Country Status (24)

Country Link
US (1) US6133304A (pt)
EP (1) EP1047450B1 (pt)
JP (1) JP2001526245A (pt)
KR (1) KR20010033473A (pt)
AR (1) AR015504A1 (pt)
AT (1) ATE225187T1 (pt)
AU (1) AU751701B2 (pt)
BR (1) BR9814422A (pt)
CA (1) CA2305436A1 (pt)
CO (1) CO4970775A1 (pt)
DE (1) DE69808518T2 (pt)
DK (1) DK1047450T3 (pt)
ES (1) ES2184340T3 (pt)
HU (1) HUP0100427A3 (pt)
IL (1) IL135428A0 (pt)
IS (1) IS5446A (pt)
NO (1) NO20003256L (pt)
NZ (1) NZ503962A (pt)
PE (1) PE20000065A1 (pt)
PL (1) PL341335A1 (pt)
PT (1) PT1047450E (pt)
UY (1) UY25321A1 (pt)
WO (1) WO1999032150A1 (pt)
ZA (1) ZA9811794B (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0009244A (pt) * 1999-03-03 2002-04-16 Procter & Gamble Inibidores de metaloprotease di-hétero substituìdos
US6376524B1 (en) 2000-06-21 2002-04-23 Sunesis Pharmaceuticals, Inc. Triphenyl compounds as interleukin-4 antagonists
GB0100761D0 (en) 2001-01-11 2001-02-21 Biocompatibles Ltd Drug delivery from stents
KR100854424B1 (ko) 2001-01-29 2008-08-27 3-디멘져널 파마슈티칼즈 인코오포레이티드 치환된 인돌 및 인테그린 길항제로서의 이들의 용도
DE10125882B4 (de) * 2001-05-28 2007-03-29 Esparma Gmbh Arzneimittel enthaltend Ambroxol, dessen Salze und/oder Prodrugs zusammen mit α-Liponsäure im Rahmen der Behandlung des Diabetes mellitus
WO2003015762A1 (fr) * 2001-08-20 2003-02-27 Ono Pharmaceutical Co., Ltd. Agent therapeutique pour insuffisance cardiaque
US7071211B2 (en) * 2002-09-27 2006-07-04 Bausch & Lomb Inc. Small organic molecules that increase the activity of gelatinase a in ocular cells
EP1545287B1 (en) * 2002-10-04 2012-12-05 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, represented by THE DEPARTMENT OF HEALTH & HUMAN SERVICES Vasoregulating compounds and methods of their use
CA2504953C (en) * 2002-11-07 2013-08-20 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services A new target for angiogenesis and anti-angiogenesis therapy
US20040225077A1 (en) 2002-12-30 2004-11-11 Angiotech International Ag Drug delivery from rapid gelling polymer composition
EP1660661A2 (en) * 2003-08-08 2006-05-31 Arriva Pharmaceuticals, Inc. Methods of protein production in yeast
SI1684719T1 (sl) * 2003-11-14 2012-07-31 Baxter Int Sestavki alfa antitripsina in postopki zdravljenja ob uporabi takih sestavkov
AU2005221151A1 (en) 2004-03-09 2005-09-22 Arriva Pharmaceuticals, Inc. Treatment of chronic obstructive pulmonary disease by low dose inhalation of protease inhibitor
AU2005268781A1 (en) * 2004-08-02 2006-02-09 Genmedica Therapeutics Sl Compounds for inhibiting copper-containing amine oxidases and uses thereof
CN100367956C (zh) * 2006-08-29 2008-02-13 陈俊云 用于治疗高血压的药物
JP2011525194A (ja) * 2008-06-20 2011-09-15 キネメッド, インコーポレイテッド 線維性疾患または病態を治療するための組成物
WO2010011302A1 (en) * 2008-07-22 2010-01-28 Chdi, Inc. Certain kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
US20120270884A1 (en) * 2009-10-01 2012-10-25 Symphony Evolution, Inc. Methods of Treating Aneurysmal Dilatation, Blood Vessel Wall Weakness and Specifically Abdominal Aortic and Thoracic Aneurysm Using Matrix Metalloprotease-2 Inhibitors
CN106518845B (zh) 2011-08-30 2019-09-13 Chdi基金会股份有限公司 犬尿氨酸-3-单加氧酶抑制剂、药物组合物及其使用方法
BR112014004845A2 (pt) 2011-08-30 2017-04-04 Chdi Foundation Inc pelo menos uma entidade química; pelo menos um composto; composição farmacêutica; uso de uma quantidade terapeuticamente eficaz de pelo menos uma entidade química; composição farmacêutica embalada
WO2014210062A1 (en) * 2013-06-26 2014-12-31 Stealth Peptides International, Inc. Methods for the regulation of matrix metalloproteinase expression
SG11201700341PA (en) 2014-07-17 2017-02-27 Chdi Foundation Inc Methods and compositions for treating hiv-related disorders
WO2017117130A1 (en) 2015-12-28 2017-07-06 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for inhibiting human immunodeficiency virus (hiv) release from infected cells

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE148632T1 (de) * 1990-05-11 1997-02-15 Pfizer Synergistische therapeutische zusammensetzungen und verfahren
BR9604882A (pt) * 1995-02-10 1998-05-19 Searle & Co Terapia de combinação de inibidor de enzima de conversão de antgiotensina e quantidade de efeito colateral reduzido de antagonista de aldosterona para tratamento de doença cardiovascular
KR20000011095A (ko) * 1996-05-17 2000-02-25 로즈 암스트롱, 크리스틴 에이. 트러트웨인 비페닐술폰아미드 매트릭스 메탈로프로테이나아제 억제제
US5756545A (en) * 1997-04-21 1998-05-26 Warner-Lambert Company Biphenysulfonamide matrix metal alloproteinase inhibitors

Also Published As

Publication number Publication date
PL341335A1 (en) 2001-04-09
AU1522099A (en) 1999-07-12
JP2001526245A (ja) 2001-12-18
DE69808518D1 (de) 2002-11-07
IL135428A0 (en) 2001-05-20
EP1047450A1 (en) 2000-11-02
BR9814422A (pt) 2000-10-10
CO4970775A1 (es) 2000-11-07
PE20000065A1 (es) 2000-02-11
NZ503962A (en) 2002-03-28
NO20003256D0 (no) 2000-06-22
IS5446A (is) 2000-04-14
WO1999032150A1 (en) 1999-07-01
EP1047450B1 (en) 2002-10-02
HUP0100427A3 (en) 2002-11-28
AR015504A1 (es) 2001-05-02
ZA9811794B (en) 1999-06-29
US6133304A (en) 2000-10-17
ES2184340T3 (es) 2003-04-01
UY25321A1 (es) 2004-07-30
AU751701B2 (en) 2002-08-22
NO20003256L (no) 2000-06-22
ATE225187T1 (de) 2002-10-15
DK1047450T3 (da) 2003-01-27
CA2305436A1 (en) 1999-07-01
HUP0100427A2 (hu) 2001-06-28
KR20010033473A (ko) 2001-04-25
DE69808518T2 (de) 2003-06-26

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