PT1047450E - Combinacoes inibidor ace - inibidor mmp - Google Patents
Combinacoes inibidor ace - inibidor mmpInfo
- Publication number
- PT1047450E PT1047450E PT98959416T PT98959416T PT1047450E PT 1047450 E PT1047450 E PT 1047450E PT 98959416 T PT98959416 T PT 98959416T PT 98959416 T PT98959416 T PT 98959416T PT 1047450 E PT1047450 E PT 1047450E
- Authority
- PT
- Portugal
- Prior art keywords
- inhibitor
- combinations
- mmp
- ace
- ace inhibitor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/556—Angiotensin converting enzyme inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6859497P | 1997-12-23 | 1997-12-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1047450E true PT1047450E (pt) | 2003-02-28 |
Family
ID=22083543
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT98959416T PT1047450E (pt) | 1997-12-23 | 1998-11-10 | Combinacoes inibidor ace - inibidor mmp |
Country Status (24)
Country | Link |
---|---|
US (1) | US6133304A (pt) |
EP (1) | EP1047450B1 (pt) |
JP (1) | JP2001526245A (pt) |
KR (1) | KR20010033473A (pt) |
AR (1) | AR015504A1 (pt) |
AT (1) | ATE225187T1 (pt) |
AU (1) | AU751701B2 (pt) |
BR (1) | BR9814422A (pt) |
CA (1) | CA2305436A1 (pt) |
CO (1) | CO4970775A1 (pt) |
DE (1) | DE69808518T2 (pt) |
DK (1) | DK1047450T3 (pt) |
ES (1) | ES2184340T3 (pt) |
HU (1) | HUP0100427A3 (pt) |
IL (1) | IL135428A0 (pt) |
IS (1) | IS5446A (pt) |
NO (1) | NO20003256L (pt) |
NZ (1) | NZ503962A (pt) |
PE (1) | PE20000065A1 (pt) |
PL (1) | PL341335A1 (pt) |
PT (1) | PT1047450E (pt) |
UY (1) | UY25321A1 (pt) |
WO (1) | WO1999032150A1 (pt) |
ZA (1) | ZA9811794B (pt) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR0009244A (pt) * | 1999-03-03 | 2002-04-16 | Procter & Gamble | Inibidores de metaloprotease di-hétero substituìdos |
US6376524B1 (en) | 2000-06-21 | 2002-04-23 | Sunesis Pharmaceuticals, Inc. | Triphenyl compounds as interleukin-4 antagonists |
GB0100761D0 (en) | 2001-01-11 | 2001-02-21 | Biocompatibles Ltd | Drug delivery from stents |
KR100854424B1 (ko) | 2001-01-29 | 2008-08-27 | 3-디멘져널 파마슈티칼즈 인코오포레이티드 | 치환된 인돌 및 인테그린 길항제로서의 이들의 용도 |
DE10125882B4 (de) * | 2001-05-28 | 2007-03-29 | Esparma Gmbh | Arzneimittel enthaltend Ambroxol, dessen Salze und/oder Prodrugs zusammen mit α-Liponsäure im Rahmen der Behandlung des Diabetes mellitus |
WO2003015762A1 (fr) * | 2001-08-20 | 2003-02-27 | Ono Pharmaceutical Co., Ltd. | Agent therapeutique pour insuffisance cardiaque |
US7071211B2 (en) * | 2002-09-27 | 2006-07-04 | Bausch & Lomb Inc. | Small organic molecules that increase the activity of gelatinase a in ocular cells |
EP1545287B1 (en) * | 2002-10-04 | 2012-12-05 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, represented by THE DEPARTMENT OF HEALTH & HUMAN SERVICES | Vasoregulating compounds and methods of their use |
CA2504953C (en) * | 2002-11-07 | 2013-08-20 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | A new target for angiogenesis and anti-angiogenesis therapy |
US20040225077A1 (en) | 2002-12-30 | 2004-11-11 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
EP1660661A2 (en) * | 2003-08-08 | 2006-05-31 | Arriva Pharmaceuticals, Inc. | Methods of protein production in yeast |
SI1684719T1 (sl) * | 2003-11-14 | 2012-07-31 | Baxter Int | Sestavki alfa antitripsina in postopki zdravljenja ob uporabi takih sestavkov |
AU2005221151A1 (en) | 2004-03-09 | 2005-09-22 | Arriva Pharmaceuticals, Inc. | Treatment of chronic obstructive pulmonary disease by low dose inhalation of protease inhibitor |
AU2005268781A1 (en) * | 2004-08-02 | 2006-02-09 | Genmedica Therapeutics Sl | Compounds for inhibiting copper-containing amine oxidases and uses thereof |
CN100367956C (zh) * | 2006-08-29 | 2008-02-13 | 陈俊云 | 用于治疗高血压的药物 |
JP2011525194A (ja) * | 2008-06-20 | 2011-09-15 | キネメッド, インコーポレイテッド | 線維性疾患または病態を治療するための組成物 |
WO2010011302A1 (en) * | 2008-07-22 | 2010-01-28 | Chdi, Inc. | Certain kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof |
US20120270884A1 (en) * | 2009-10-01 | 2012-10-25 | Symphony Evolution, Inc. | Methods of Treating Aneurysmal Dilatation, Blood Vessel Wall Weakness and Specifically Abdominal Aortic and Thoracic Aneurysm Using Matrix Metalloprotease-2 Inhibitors |
CN106518845B (zh) | 2011-08-30 | 2019-09-13 | Chdi基金会股份有限公司 | 犬尿氨酸-3-单加氧酶抑制剂、药物组合物及其使用方法 |
BR112014004845A2 (pt) | 2011-08-30 | 2017-04-04 | Chdi Foundation Inc | pelo menos uma entidade química; pelo menos um composto; composição farmacêutica; uso de uma quantidade terapeuticamente eficaz de pelo menos uma entidade química; composição farmacêutica embalada |
WO2014210062A1 (en) * | 2013-06-26 | 2014-12-31 | Stealth Peptides International, Inc. | Methods for the regulation of matrix metalloproteinase expression |
SG11201700341PA (en) | 2014-07-17 | 2017-02-27 | Chdi Foundation Inc | Methods and compositions for treating hiv-related disorders |
WO2017117130A1 (en) | 2015-12-28 | 2017-07-06 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Methods for inhibiting human immunodeficiency virus (hiv) release from infected cells |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE148632T1 (de) * | 1990-05-11 | 1997-02-15 | Pfizer | Synergistische therapeutische zusammensetzungen und verfahren |
BR9604882A (pt) * | 1995-02-10 | 1998-05-19 | Searle & Co | Terapia de combinação de inibidor de enzima de conversão de antgiotensina e quantidade de efeito colateral reduzido de antagonista de aldosterona para tratamento de doença cardiovascular |
KR20000011095A (ko) * | 1996-05-17 | 2000-02-25 | 로즈 암스트롱, 크리스틴 에이. 트러트웨인 | 비페닐술폰아미드 매트릭스 메탈로프로테이나아제 억제제 |
US5756545A (en) * | 1997-04-21 | 1998-05-26 | Warner-Lambert Company | Biphenysulfonamide matrix metal alloproteinase inhibitors |
-
1998
- 1998-11-10 ES ES98959416T patent/ES2184340T3/es not_active Expired - Lifetime
- 1998-11-10 HU HU0100427A patent/HUP0100427A3/hu unknown
- 1998-11-10 CA CA002305436A patent/CA2305436A1/en not_active Abandoned
- 1998-11-10 WO PCT/US1998/023993 patent/WO1999032150A1/en not_active Application Discontinuation
- 1998-11-10 US US09/485,253 patent/US6133304A/en not_active Expired - Fee Related
- 1998-11-10 DK DK98959416T patent/DK1047450T3/da active
- 1998-11-10 AT AT98959416T patent/ATE225187T1/de not_active IP Right Cessation
- 1998-11-10 JP JP2000525140A patent/JP2001526245A/ja active Pending
- 1998-11-10 PT PT98959416T patent/PT1047450E/pt unknown
- 1998-11-10 PL PL98341335A patent/PL341335A1/xx unknown
- 1998-11-10 AU AU15220/99A patent/AU751701B2/en not_active Ceased
- 1998-11-10 KR KR1020007006974A patent/KR20010033473A/ko not_active Application Discontinuation
- 1998-11-10 DE DE69808518T patent/DE69808518T2/de not_active Expired - Fee Related
- 1998-11-10 BR BR9814422-7A patent/BR9814422A/pt not_active IP Right Cessation
- 1998-11-10 NZ NZ503962A patent/NZ503962A/xx unknown
- 1998-11-10 EP EP98959416A patent/EP1047450B1/en not_active Expired - Lifetime
- 1998-11-10 IL IL13542898A patent/IL135428A0/xx unknown
- 1998-12-22 CO CO98076095A patent/CO4970775A1/es unknown
- 1998-12-22 ZA ZA9811794A patent/ZA9811794B/xx unknown
- 1998-12-22 PE PE1998001267A patent/PE20000065A1/es not_active Application Discontinuation
- 1998-12-22 AR ARP980106613A patent/AR015504A1/es not_active Application Discontinuation
- 1998-12-22 UY UY25321A patent/UY25321A1/es unknown
-
2000
- 2000-04-14 IS IS5446A patent/IS5446A/is unknown
- 2000-06-22 NO NO20003256A patent/NO20003256L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
PL341335A1 (en) | 2001-04-09 |
AU1522099A (en) | 1999-07-12 |
JP2001526245A (ja) | 2001-12-18 |
DE69808518D1 (de) | 2002-11-07 |
IL135428A0 (en) | 2001-05-20 |
EP1047450A1 (en) | 2000-11-02 |
BR9814422A (pt) | 2000-10-10 |
CO4970775A1 (es) | 2000-11-07 |
PE20000065A1 (es) | 2000-02-11 |
NZ503962A (en) | 2002-03-28 |
NO20003256D0 (no) | 2000-06-22 |
IS5446A (is) | 2000-04-14 |
WO1999032150A1 (en) | 1999-07-01 |
EP1047450B1 (en) | 2002-10-02 |
HUP0100427A3 (en) | 2002-11-28 |
AR015504A1 (es) | 2001-05-02 |
ZA9811794B (en) | 1999-06-29 |
US6133304A (en) | 2000-10-17 |
ES2184340T3 (es) | 2003-04-01 |
UY25321A1 (es) | 2004-07-30 |
AU751701B2 (en) | 2002-08-22 |
NO20003256L (no) | 2000-06-22 |
ATE225187T1 (de) | 2002-10-15 |
DK1047450T3 (da) | 2003-01-27 |
CA2305436A1 (en) | 1999-07-01 |
HUP0100427A2 (hu) | 2001-06-28 |
KR20010033473A (ko) | 2001-04-25 |
DE69808518T2 (de) | 2003-06-26 |
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