PL3638680T3 - Związki heteroaromatyczne jako inhibitory waniny - Google Patents

Związki heteroaromatyczne jako inhibitory waniny

Info

Publication number
PL3638680T3
PL3638680T3 PL18731766.4T PL18731766T PL3638680T3 PL 3638680 T3 PL3638680 T3 PL 3638680T3 PL 18731766 T PL18731766 T PL 18731766T PL 3638680 T3 PL3638680 T3 PL 3638680T3
Authority
PL
Poland
Prior art keywords
heteroaromatic compounds
vanin
inhibitors
vanin inhibitors
heteroaromatic
Prior art date
Application number
PL18731766.4T
Other languages
English (en)
Inventor
Todd Bosanac
Michael J Burke
Brian Nicholas Cook
Darren Todd Disalvo
Thomas Martin Kirrane Jr.
Yue Shen
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Publication of PL3638680T3 publication Critical patent/PL3638680T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53831,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
PL18731766.4T 2017-06-12 2018-06-08 Związki heteroaromatyczne jako inhibitory waniny PL3638680T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762518106P 2017-06-12 2017-06-12
PCT/EP2018/065140 WO2018228934A1 (en) 2017-06-12 2018-06-08 Heteroaromatic compounds as vanin inhibitors

Publications (1)

Publication Number Publication Date
PL3638680T3 true PL3638680T3 (pl) 2022-12-19

Family

ID=62631060

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18731766.4T PL3638680T3 (pl) 2017-06-12 2018-06-08 Związki heteroaromatyczne jako inhibitory waniny

Country Status (23)

Country Link
US (2) US10364255B2 (pl)
EP (1) EP3638680B1 (pl)
JP (1) JP6880243B2 (pl)
KR (1) KR102607934B1 (pl)
CN (1) CN110770242B (pl)
AR (1) AR112086A1 (pl)
AU (1) AU2018285131B2 (pl)
BR (1) BR112019021703A2 (pl)
CA (1) CA3066946A1 (pl)
CL (1) CL2019003515A1 (pl)
CO (1) CO2019013823A2 (pl)
DK (1) DK3638680T3 (pl)
EA (1) EA039223B1 (pl)
ES (1) ES2927021T3 (pl)
HU (1) HUE060597T2 (pl)
IL (1) IL271104B (pl)
MA (1) MA49374A (pl)
MX (1) MX2019014876A (pl)
PE (1) PE20200340A1 (pl)
PH (1) PH12019502693A1 (pl)
PL (1) PL3638680T3 (pl)
TW (1) TW201920196A (pl)
WO (1) WO2018228934A1 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2927021T3 (es) * 2017-06-12 2022-11-02 Boehringer Ingelheim Int Compuestos heteroaromáticos como inhibidores de vanina
EP3837263A1 (en) 2018-08-13 2021-06-23 F. Hoffmann-La Roche AG New heterocyclic compounds as monoacylglycerol lipase inhibitors
DK3844161T3 (da) * 2018-08-28 2022-12-12 Boehringer Ingelheim Int Heteroaromatiske forbindelser som vanininhibitorer.
AR117229A1 (es) 2018-12-03 2021-07-21 Boehringer Ingelheim Int Compuestos heteroaromáticos como inhibidores de vanina
EP4028403B1 (en) 2019-09-12 2023-11-22 F. Hoffmann-La Roche AG 4,4a,5,7,8,8a-hexapyrido[4,3-b][1,4]oxazin-3-one compounds as magl inhibitors
US20230107927A1 (en) 2020-02-28 2023-04-06 First Wave Bio, Inc. Methods of treating iatrogenic autoimmune colitis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602004018811D1 (de) * 2003-10-09 2009-02-12 Abbott Lab Pyrrolidinylharnstoffderivate als angiogeneseinhibitoren
EP3303303A1 (en) * 2015-05-29 2018-04-11 Pfizer Inc Novel heterocyclic compounds as inhibitors of vanin-1 enzyme
AU2017296338A1 (en) * 2016-07-14 2019-01-03 Pfizer Inc. Novel pyrimidine carboxamides as inhibitors of vanin-1 enzyme
ES2927021T3 (es) * 2017-06-12 2022-11-02 Boehringer Ingelheim Int Compuestos heteroaromáticos como inhibidores de vanina

Also Published As

Publication number Publication date
EP3638680A1 (en) 2020-04-22
MX2019014876A (es) 2020-02-13
US10364255B2 (en) 2019-07-30
PE20200340A1 (es) 2020-02-14
CA3066946A1 (en) 2018-12-20
IL271104B (en) 2022-03-01
CN110770242A (zh) 2020-02-07
CN110770242B (zh) 2022-08-19
AU2018285131B2 (en) 2021-11-11
WO2018228934A1 (en) 2018-12-20
AR112086A1 (es) 2019-09-18
DK3638680T3 (da) 2022-09-05
KR102607934B1 (ko) 2023-12-01
EA039223B1 (ru) 2021-12-20
BR112019021703A2 (pt) 2020-05-12
CL2019003515A1 (es) 2020-06-19
TW201920196A (zh) 2019-06-01
PH12019502693A1 (en) 2020-07-13
AU2018285131A1 (en) 2019-10-31
US20190263828A1 (en) 2019-08-29
MA49374A (fr) 2021-04-21
EP3638680B1 (en) 2022-08-10
ES2927021T3 (es) 2022-11-02
EA202090014A1 (ru) 2020-05-12
CO2019013823A2 (es) 2020-01-17
HUE060597T2 (hu) 2023-04-28
US20180354968A1 (en) 2018-12-13
JP2020522517A (ja) 2020-07-30
JP6880243B2 (ja) 2021-06-02
IL271104A (en) 2020-01-30
KR20200013718A (ko) 2020-02-07

Similar Documents

Publication Publication Date Title
HUS2400003I1 (hu) Kináz inhibitorként alkalmas vegyületek
IL289474A (en) Substituted thiazolo-pyridine compounds as malt1 inhibitors
PT3371190T (pt) Compostos heterocíclicos como inibidores de pi3k-gamma
IL255750A (en) Heterocyclic compounds as kinase inhibitors
HRP20200133T1 (hr) Novi supstituirani derivati cijanoindolina kao inhibitori nik
IL271104B (en) Heteroaromatic compounds as vanin inhibitors
IL266745B (en) Benzodiazolonium compounds as enac inhibitors
IL283397A (en) Heteroaromatic compounds as vanin inhibitors
IL280898A (en) Heteroaromatic compounds as vanin inhibitors
PL3891142T3 (pl) Związki heteroaromatyczne jako inhibitory waniny
IL264465B (en) Substituted thiazolo-pyridine compounds as malt1 inhibitors
GB201613945D0 (en) Compounds useful as kinase inhibitors
GB201522245D0 (en) Compounds useful as kinase inhibitors