PL3344655T3 - Zastosowanie przeciwciał anty-cd40 w leczeniu toczniowego zapalenia nerek - Google Patents

Zastosowanie przeciwciał anty-cd40 w leczeniu toczniowego zapalenia nerek

Info

Publication number
PL3344655T3
PL3344655T3 PL16763663.8T PL16763663T PL3344655T3 PL 3344655 T3 PL3344655 T3 PL 3344655T3 PL 16763663 T PL16763663 T PL 16763663T PL 3344655 T3 PL3344655 T3 PL 3344655T3
Authority
PL
Poland
Prior art keywords
antibodies
treatment
lupus nephritis
nephritis
lupus
Prior art date
Application number
PL16763663.8T
Other languages
English (en)
Inventor
Scott Ronald Brodeur
Thomas B. Freeman
Gerald Henry NABOZNY
Meera RAMANUJAM
Paul SCHOLL
Juergen STEFFGEN
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Publication of PL3344655T3 publication Critical patent/PL3344655T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/71Decreased effector function due to an Fc-modification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL16763663.8T 2015-09-01 2016-08-31 Zastosowanie przeciwciał anty-cd40 w leczeniu toczniowego zapalenia nerek PL3344655T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562212810P 2015-09-01 2015-09-01
US201562257336P 2015-11-19 2015-11-19
US201662287587P 2016-01-27 2016-01-27
PCT/US2016/049558 WO2017040566A1 (en) 2015-09-01 2016-08-31 Use of anti-cd40 antibodies for treatment of lupus nephritis

Publications (1)

Publication Number Publication Date
PL3344655T3 true PL3344655T3 (pl) 2024-02-19

Family

ID=56896810

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16763663.8T PL3344655T3 (pl) 2015-09-01 2016-08-31 Zastosowanie przeciwciał anty-cd40 w leczeniu toczniowego zapalenia nerek

Country Status (15)

Country Link
US (3) US20170058038A1 (pl)
EP (1) EP3344655B1 (pl)
JP (2) JP2018529661A (pl)
KR (1) KR20180039172A (pl)
CN (1) CN107922501A (pl)
AU (1) AU2016317028B2 (pl)
BR (1) BR112018001907A2 (pl)
CA (1) CA2993996A1 (pl)
CL (1) CL2018000317A1 (pl)
DK (1) DK3344655T3 (pl)
HU (1) HUE063528T2 (pl)
MX (1) MX2018002447A (pl)
PH (1) PH12018500445A1 (pl)
PL (1) PL3344655T3 (pl)
WO (1) WO2017040566A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017220989A1 (en) 2016-06-20 2017-12-28 Kymab Limited Anti-pd-l1 and il-2 cytokines
EP3813950A1 (en) * 2018-06-29 2021-05-05 Boehringer Ingelheim International GmbH Anti-cd40 antibodies for use in treating autoimmune disease
MX2021006360A (es) * 2018-11-30 2021-08-11 Jiangsu Hengrui Medicine Co Composicion farmaceutica de anticuerpo cd40 y uso de la misma.
JP2024506831A (ja) 2021-01-28 2024-02-15 リジェネロン・ファーマシューティカルズ・インコーポレイテッド サイトカイン放出症候群を治療するための組成物及び方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
JPS6023084B2 (ja) 1979-07-11 1985-06-05 味の素株式会社 代用血液
US4485045A (en) 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
US4640835A (en) 1981-10-30 1987-02-03 Nippon Chemiphar Company, Ltd. Plasminogen activator derivatives
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4544545A (en) 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
US4496689A (en) 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
DE3675588D1 (de) 1985-06-19 1990-12-20 Ajinomoto Kk Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist.
US4791192A (en) 1986-06-26 1988-12-13 Takeda Chemical Industries, Ltd. Chemically modified protein with polyethyleneglycol
US5013556A (en) 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
DE69233254T2 (de) 1991-06-14 2004-09-16 Genentech, Inc., South San Francisco Humanisierter Heregulin Antikörper
WO1994004679A1 (en) 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
JPH08500826A (ja) 1992-08-21 1996-01-30 ジェネンテク,インコーポレイテッド Lfa−1仲介疾患を処置する方法
US6037454A (en) 1996-11-27 2000-03-14 Genentech, Inc. Humanized anti-CD11a antibodies
US20030059427A1 (en) * 2000-04-28 2003-03-27 Force Walker R. Isolation and characterization of highly active anti-CD40 antibody
US8277810B2 (en) * 2003-11-04 2012-10-02 Novartis Vaccines & Diagnostics, Inc. Antagonist anti-CD40 antibodies
RU2006141632A (ru) * 2004-04-27 2008-06-10 Новартис Вэксинес Энд Дайэгностикс, Инк. (Us) Антагонистические моноклональные анти-cd40-антитела и способы их применения
ATE485057T1 (de) * 2005-05-26 2010-11-15 Seattle Genetics Inc Humanisierte antikörper gegen cd40 und verfahren zu ihrer anwendung
MEP39508A (en) * 2006-04-21 2011-02-10 Novartis Ag Antagonist anti-cd40 antibody pharmaceutical compositions
EA031872B1 (ru) 2010-03-31 2019-03-29 Бёрингер Ингельхайм Интернациональ Гмбх Гуманизированное антитело к cd40, его применение, фармацевтическая композиция, содержащая это антитело, и выделенный полинуклеотид, кодирующий его
KR20190122889A (ko) * 2011-04-29 2019-10-30 아펙시젠, 인코포레이티드 항-cd40 항체 및 사용 방법
US20140004131A1 (en) * 2012-05-04 2014-01-02 Novartis Ag Antibody formulation

Also Published As

Publication number Publication date
US20230265203A1 (en) 2023-08-24
MX2018002447A (es) 2018-06-15
EP3344655B1 (en) 2023-07-26
AU2016317028A1 (en) 2018-02-22
BR112018001907A2 (pt) 2018-09-25
JP2018529661A (ja) 2018-10-11
CN107922501A (zh) 2018-04-17
AU2016317028B2 (en) 2021-09-09
CL2018000317A1 (es) 2018-07-20
DK3344655T3 (da) 2023-10-09
US20190177420A1 (en) 2019-06-13
WO2017040566A1 (en) 2017-03-09
PH12018500445A1 (en) 2018-09-10
CA2993996A1 (en) 2017-03-09
KR20180039172A (ko) 2018-04-17
JP2021185169A (ja) 2021-12-09
HUE063528T2 (hu) 2024-01-28
US20170058038A1 (en) 2017-03-02
EP3344655A1 (en) 2018-07-11

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