PL3203997T3 - Kwas walproinowy do leczenia lub zapobiegania stanom patologicznym związanym z nadmiernym odkładaniem się fibryny i/lub tworzeniem zakrzepów - Google Patents

Kwas walproinowy do leczenia lub zapobiegania stanom patologicznym związanym z nadmiernym odkładaniem się fibryny i/lub tworzeniem zakrzepów

Info

Publication number
PL3203997T3
PL3203997T3 PL15790632T PL15790632T PL3203997T3 PL 3203997 T3 PL3203997 T3 PL 3203997T3 PL 15790632 T PL15790632 T PL 15790632T PL 15790632 T PL15790632 T PL 15790632T PL 3203997 T3 PL3203997 T3 PL 3203997T3
Authority
PL
Poland
Prior art keywords
prevention
treatment
conditions associated
pathological conditions
valproic acid
Prior art date
Application number
PL15790632T
Other languages
English (en)
Inventor
Sverker JERN
Jonas Faijerson SÄLJÖ
Niklas BERGH
Original Assignee
Cereno Scientific Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cereno Scientific Ab filed Critical Cereno Scientific Ab
Publication of PL3203997T3 publication Critical patent/PL3203997T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL15790632T 2014-10-08 2015-10-08 Kwas walproinowy do leczenia lub zapobiegania stanom patologicznym związanym z nadmiernym odkładaniem się fibryny i/lub tworzeniem zakrzepów PL3203997T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1417828.9A GB201417828D0 (en) 2014-10-08 2014-10-08 New methods and compositions
PCT/GB2015/052950 WO2016055797A2 (en) 2014-10-08 2015-10-08 Compounds and compositions for the treatment or prevention of pathological conditions associated with excess fibrin deposition and/or thrombus formation
EP15790632.2A EP3203997B1 (en) 2014-10-08 2015-10-08 Valproic acid for the treatment or prevention of pathological conditions associated with excess fibrin deposition and/or thrombus formation

Publications (1)

Publication Number Publication Date
PL3203997T3 true PL3203997T3 (pl) 2022-05-16

Family

ID=51947070

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15790632T PL3203997T3 (pl) 2014-10-08 2015-10-08 Kwas walproinowy do leczenia lub zapobiegania stanom patologicznym związanym z nadmiernym odkładaniem się fibryny i/lub tworzeniem zakrzepów

Country Status (21)

Country Link
US (3) US10111845B2 (pl)
EP (2) EP4066825A1 (pl)
JP (2) JP6787901B2 (pl)
KR (1) KR20170063857A (pl)
CN (3) CN107205975A (pl)
AU (1) AU2015329795B2 (pl)
BR (1) BR112017007144A2 (pl)
CA (2) CA3234641A1 (pl)
CL (1) CL2017000866A1 (pl)
DK (1) DK3203997T3 (pl)
ES (1) ES2913225T3 (pl)
GB (1) GB201417828D0 (pl)
HU (1) HUE058316T2 (pl)
IL (1) IL251142B (pl)
MX (2) MX2017004558A (pl)
MY (1) MY192055A (pl)
NZ (1) NZ730307A (pl)
PL (1) PL3203997T3 (pl)
RU (1) RU2732761C2 (pl)
SG (1) SG11201702058XA (pl)
WO (1) WO2016055797A2 (pl)

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ES2760261T3 (es) 2014-02-13 2020-05-13 Incyte Corp Ciclopropilaminas como inhibidores de LSD1
WO2016007722A1 (en) 2014-07-10 2016-01-14 Incyte Corporation Triazolopyridines and triazolopyrazines as lsd1 inhibitors
US9695168B2 (en) 2014-07-10 2017-07-04 Incyte Corporation Substituted imidazo[1,5-α]pyridines and imidazo[1,5-α]pyrazines as LSD1 inhibitors
WO2016007736A1 (en) 2014-07-10 2016-01-14 Incyte Corporation Imidazopyrazines as lsd1 inhibitors
GB201417828D0 (en) 2014-10-08 2014-11-19 Cereno Scient Ab New methods and compositions
MX2017012699A (es) 2015-04-03 2018-02-09 Incyte Corp Compuestos heterociclicos como inhibidores de demetilasa 1 especifica de lisina (lsd1).
KR20180051523A (ko) 2015-08-12 2018-05-16 인사이트 코포레이션 Lsd1 저해제의 염
ES2969021T3 (es) * 2016-04-08 2024-05-16 Cereno Scient Ab Formulaciones farmacéuticas de liberación retardada que comprenden ácido valproico y usos de las mismas
US20200179381A1 (en) * 2016-04-08 2020-06-11 Cereno Scientific Ab Compounds and compositions for the treatment or prevention of pathological conditions associated with excess fibrin deposition and/or thrombus formation
WO2020047198A1 (en) 2018-08-31 2020-03-05 Incyte Corporation Salts of an lsd1 inhibitor and processes for preparing the same
US20230069590A1 (en) * 2020-01-16 2023-03-02 The Regents Of The University Of Michigan Concentrated sodium valproate for rapid delivery
CN111450072B (zh) * 2020-05-07 2022-07-15 江苏艾立康医药科技有限公司 一种替格瑞洛控释片及其制备方法
GB2613900B (en) * 2021-12-20 2024-01-17 Cereno Scient Ab Novel compounds and methods of use thereof

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Also Published As

Publication number Publication date
HUE058316T2 (hu) 2022-07-28
US20220401393A1 (en) 2022-12-22
WO2016055797A3 (en) 2016-06-09
DK3203997T3 (da) 2022-05-23
EP3203997A2 (en) 2017-08-16
ES2913225T3 (es) 2022-06-01
MY192055A (en) 2022-07-25
IL251142A0 (en) 2017-04-30
KR20170063857A (ko) 2017-06-08
JP2021008523A (ja) 2021-01-28
EP4066825A1 (en) 2022-10-05
US20190015360A1 (en) 2019-01-17
RU2732761C2 (ru) 2020-09-22
SG11201702058XA (en) 2017-04-27
AU2015329795B2 (en) 2021-03-25
IL251142B (en) 2022-07-01
JP7305605B2 (ja) 2023-07-10
BR112017007144A2 (pt) 2017-12-19
US20180177751A1 (en) 2018-06-28
GB201417828D0 (en) 2014-11-19
MX2022007221A (es) 2022-07-12
JP2017532376A (ja) 2017-11-02
US11400064B2 (en) 2022-08-02
MX2017004558A (es) 2017-12-14
NZ730307A (en) 2024-01-26
RU2017114933A (ru) 2018-11-12
AU2015329795A1 (en) 2017-04-13
RU2017114933A3 (pl) 2019-05-16
JP6787901B2 (ja) 2020-11-18
CN115581691A (zh) 2023-01-10
CA3234641A1 (en) 2016-04-14
US10111845B2 (en) 2018-10-30
CL2017000866A1 (es) 2017-11-24
CN115721635A (zh) 2023-03-03
CA2964041A1 (en) 2016-04-14
WO2016055797A2 (en) 2016-04-14
EP3203997B1 (en) 2022-03-02
CA2964041C (en) 2024-04-09
CN107205975A (zh) 2017-09-26

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