PL2993186T3 - Przeciwciało monoklonalne i sposób jego otrzymywania - Google Patents
Przeciwciało monoklonalne i sposób jego otrzymywaniaInfo
- Publication number
- PL2993186T3 PL2993186T3 PL15171431T PL15171431T PL2993186T3 PL 2993186 T3 PL2993186 T3 PL 2993186T3 PL 15171431 T PL15171431 T PL 15171431T PL 15171431 T PL15171431 T PL 15171431T PL 2993186 T3 PL2993186 T3 PL 2993186T3
- Authority
- PL
- Poland
- Prior art keywords
- monoclonal antibody
- monoclonal
- antibody
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Transplantation (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN650CH2008 | 2008-03-14 | ||
EP08873217A EP2265644A4 (en) | 2008-03-14 | 2008-09-04 | MONOCLONAL ANTIBODY AND CORRESPONDING METHOD |
PCT/IN2008/000562 WO2009113083A1 (en) | 2008-03-14 | 2008-09-04 | A monoclonal antibody and a method thereof |
EP15171431.8A EP2993186B1 (en) | 2008-03-14 | 2008-09-04 | A monoclonal antibody and a method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2993186T3 true PL2993186T3 (pl) | 2020-02-28 |
Family
ID=41064805
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL15171431T PL2993186T3 (pl) | 2008-03-14 | 2008-09-04 | Przeciwciało monoklonalne i sposób jego otrzymywania |
Country Status (26)
Country | Link |
---|---|
US (6) | US8524233B2 (pl) |
EP (2) | EP2993186B1 (pl) |
JP (3) | JP2011513479A (pl) |
KR (1) | KR20100126811A (pl) |
CN (1) | CN101970493A (pl) |
AR (1) | AR072247A1 (pl) |
AU (1) | AU2008352540B2 (pl) |
BR (1) | BRPI0822447A2 (pl) |
CA (1) | CA2716919C (pl) |
CL (1) | CL2009000618A1 (pl) |
CO (1) | CO6331445A2 (pl) |
DK (1) | DK2993186T3 (pl) |
EA (1) | EA201001467A1 (pl) |
ES (1) | ES2759075T3 (pl) |
HK (1) | HK1223941A1 (pl) |
IL (1) | IL207917A0 (pl) |
MX (1) | MX2010010085A (pl) |
MY (1) | MY159517A (pl) |
NZ (1) | NZ587632A (pl) |
PL (1) | PL2993186T3 (pl) |
PT (1) | PT2993186T (pl) |
TW (1) | TWI485160B (pl) |
UA (1) | UA104587C2 (pl) |
UY (1) | UY31710A (pl) |
WO (1) | WO2009113083A1 (pl) |
ZA (1) | ZA201005843B (pl) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY154819A (en) * | 2006-12-26 | 2015-07-31 | Centro Inmunologia Molecular | Pharmaceutical compositions with capacity to induce adoptosis in tumor cells for the diagnosis and treatment of the b-cell chroniclymphocytic leukemia |
BRPI0822447A2 (pt) | 2008-03-14 | 2015-06-16 | Biocon Ltd | Anticorpo monoclonal e método do mesmo |
WO2012019168A2 (en) | 2010-08-06 | 2012-02-09 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
DK3590949T3 (da) | 2010-10-01 | 2022-07-11 | Modernatx Inc | Ribonukleinsyrer indeholdende n1-methyl-pseudouracil og anvendelse heraf |
US8710200B2 (en) | 2011-03-31 | 2014-04-29 | Moderna Therapeutics, Inc. | Engineered nucleic acids encoding a modified erythropoietin and their expression |
US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
RU2648950C2 (ru) | 2011-10-03 | 2018-04-02 | Модерна Терапьютикс, Инк. | Модифицированные нуклеозиды, нуклеотиды и нуклеиновые кислоты и их применение |
US20130156849A1 (en) | 2011-12-16 | 2013-06-20 | modeRNA Therapeutics | Modified nucleoside, nucleotide, and nucleic acid compositions |
US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
WO2013151667A1 (en) | 2012-04-02 | 2013-10-10 | modeRNA Therapeutics | Modified polynucleotides |
US9303079B2 (en) | 2012-04-02 | 2016-04-05 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
RS63237B1 (sr) | 2012-11-26 | 2022-06-30 | Modernatx Inc | Terminalno modifikovana rnk |
US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
KR102062784B1 (ko) * | 2013-07-23 | 2020-01-07 | 바이오콘 리미티드 | 단백질 내 푸코실화 수준을 제어하는 방법 |
NZ746944A (en) | 2013-07-23 | 2021-07-30 | Biocon Ltd | Use of a cd6 binding partner and method based thereon |
WO2015048744A2 (en) | 2013-09-30 | 2015-04-02 | Moderna Therapeutics, Inc. | Polynucleotides encoding immune modulating polypeptides |
KR20160067219A (ko) | 2013-10-03 | 2016-06-13 | 모더나 세라퓨틱스, 인코포레이티드 | 저밀도 지단백질 수용체를 암호화하는 폴리뉴클레오타이드 |
CN104497141B (zh) * | 2014-12-31 | 2017-10-10 | 百泰生物药业有限公司 | 抗人cd6分子的治疗性抗体 |
JP6930916B2 (ja) * | 2015-02-12 | 2021-09-01 | ユニヴァーシティ オブ サザン カリフォルニアUniversity of Southern California | 疾患予防および治療における成長ホルモン受容体の遮断剤 |
WO2017218750A1 (en) | 2016-06-15 | 2017-12-21 | The Cleveland Clinic Foundation | Novel anti-cd6 antibodies for treating t-cell mediated conditions |
AU2017345390A1 (en) * | 2016-10-18 | 2019-05-02 | Biocon Limited | Use of itolizumab to reduce phosphorylation of CD6 |
DK3529274T3 (da) * | 2016-10-21 | 2024-06-17 | Biocon Ltd | Monoklonalt antistof og fremgangsmåde til anvendelse til behandling af lupus |
CN108178797B (zh) * | 2017-12-29 | 2020-12-01 | 西南大学 | 一种抗家蚕BmSRC多克隆抗血清、制备方法及应用 |
EP3759140A1 (en) | 2018-02-27 | 2021-01-06 | Equillium, Inc. | Anti cd6 antibodies for treating severe asthma |
WO2020006568A1 (en) * | 2018-06-29 | 2020-01-02 | City Of Hope | Cd6 targeted chimeric antigen receptors for treatent of certain autoimmune disorders |
BR112021016967A2 (pt) | 2019-02-26 | 2021-11-23 | Equillium Inc | Composições de anticorpo anti-cd6 e métodos para tratar lúpus |
JP7137696B2 (ja) | 2019-05-14 | 2022-09-14 | プロヴェンション・バイオ・インコーポレイテッド | 1型糖尿病を予防するための方法および組成物 |
US20230151107A1 (en) * | 2020-04-04 | 2023-05-18 | Biocon Limited | Anti-cd6 antibody compositions and methods for treating and reducing negative effects of a coronavirus including covid-19 |
AU2021287998A1 (en) | 2020-06-11 | 2023-02-02 | Benaroya Research Institute At Virginia Mason | Methods and compositions for preventing type 1 diabetes |
WO2023036349A1 (es) | 2021-09-08 | 2023-03-16 | Centro De Inmunologia Molecular | Uso de anticuerpos monoclonales anti-cd6 en la prevención del daño celular y orgánico derivado de una respuesta hiper-inflamatoria |
Family Cites Families (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US699755A (en) | 1902-03-06 | 1902-05-13 | Ira G Hoag | Train-order box in connection with semaphores. |
US6162432A (en) | 1991-10-07 | 2000-12-19 | Biogen, Inc. | Method of prophylaxis or treatment of antigen presenting cell driven skin conditions using inhibitors of the CD2/LFA-3 interaction |
EP0631783A1 (en) | 1993-06-03 | 1995-01-04 | Mitsubishi Chemical Corporation | Antiviral combinations of 2',3'-di-deoxyribonucleosides with 6-benzyl-1-ethoxymethyl-5-substituted uracil derivatives |
AU703694B2 (en) | 1993-11-02 | 1999-04-01 | Bristol-Myers Squibb Company | CD6 ligand |
US5998172A (en) | 1993-11-02 | 1999-12-07 | Duke University | Anti-CD6 ligand antibodies |
CU22615A1 (es) | 1994-06-30 | 2000-02-10 | Centro Inmunologia Molecular | Procedimiento de obtención de anticuerpos monoclonales murinos menos inmunogénicos. anticuerpos monoclonales obtenidos |
US6267958B1 (en) | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
EP1516628B1 (en) | 1995-07-27 | 2013-08-21 | Genentech, Inc. | Stable isotonic lyophilized protein formulation |
CU22584A1 (es) | 1995-11-17 | 1999-11-03 | Centro Inmunologia Molecular | Composiciones farmacéuticas que contienen un anticuerpo monoclonal que reconoce el antígeno de diferenciación leucocitario humano cd6 y sus usos para el diagnóstico y tratamiento de la psoriasis |
EA002271B1 (ru) | 1996-03-20 | 2002-02-28 | Хехст Марион Руссель | ТРИЦИКЛИЧЕСКИЕ СОЕДИНЕНИЯ, ОБЛАДАЮЩИЕ АКТИВНОСТЬЮ В ОТНОШЕНИИ ИНТЕГРИНОВ, В ЧАСТНОСТИ В ОТНОШЕНИИ ИНТЕГРИНА АЛЬФАvБЕТА 3, СПОСОБ ИХ ПОЛУЧЕНИЯ И ПРОМЕЖУТОЧНЫЕ СОЕДИНЕНИЯ, ИСПОЛЬЗУЕМЫЕ В ЭТОМ СПОСОБЕ, ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ МЕДИКАМЕНТОВ И СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ |
EP0977991A4 (en) * | 1997-03-03 | 2004-12-15 | Bristol Myers Squibb Co | MONOCLONAL ANTIBODIES FOR HUMAN CD6 |
WO1998047531A2 (en) * | 1997-04-21 | 1998-10-29 | Arch Development Corporation | Fc receptor non-binding anti-cd3 monoclonal antibodies deliver a partial tcr signal and induce clonal anergy |
WO2000058362A1 (en) * | 1999-03-26 | 2000-10-05 | Human Genome Sciences, Inc. | Neutrokine-alpha binding proteins and methods based thereon |
CA2372603C (en) | 1999-05-07 | 2015-11-17 | Genentech, Inc. | Treatment of autoimmune diseases with antagonists which bind to b cell surface markers |
JP2003527861A (ja) * | 2000-03-16 | 2003-09-24 | ジェネンテック・インコーポレーテッド | 増強した抗血液凝固能を持つ抗組織因子抗体 |
EP1283721A4 (en) * | 2000-05-26 | 2004-07-07 | Smithkline Beecham Corp | ANTI-RANK-LIGAND-BINDING MONOCLONAL ANTIBODIES USEFUL FOR TREATING DISEASES CAUSED BY THE RANK-LIGANDS |
ES2192128B1 (es) | 2001-04-27 | 2005-01-01 | Universidad De Vigo | Anticuerpo monoclonal humano que reconoce especificamente la molecula humana cd69, y su uso en terapia. |
CA2454587C (en) | 2001-07-25 | 2012-11-13 | Protein Design Labs, Inc. | Stable lyophilized pharmaceutical formulation of igg antibodies |
WO2004019861A2 (en) | 2002-08-28 | 2004-03-11 | Pharmacia Corporation | Stable ph optimized formulation of a modified antibody |
EP1460088A1 (en) * | 2003-03-21 | 2004-09-22 | Biotest AG | Humanized anti-CD4 antibody with immunosuppressive properties |
PL1610820T5 (pl) | 2003-04-04 | 2014-01-31 | Genentech Inc | Preparaty zawierające wysokoskoncentrowane przeciwciała i białka |
ES2337473T3 (es) | 2004-02-19 | 2010-04-26 | Genentech, Inc. | Anticuerpos reparadores con cdr. |
AU2005250499B2 (en) | 2004-06-03 | 2011-12-08 | Novimmune S.A. | Anti-CD3 antibodies and methods of use thereof |
JP4652414B2 (ja) | 2004-11-12 | 2011-03-16 | ゼンコー・インコーポレイテッド | FcRnとの変化した結合を有するFc変異体 |
EP1841456A2 (en) | 2005-01-28 | 2007-10-10 | Wyeth | Stabilized liquid polypeptide formulations |
WO2007142667A2 (en) | 2005-10-13 | 2007-12-13 | Human Genome Sciences, Inc. | Treatment of patients with autoantibody positive disease |
KR20090021298A (ko) | 2006-06-14 | 2009-03-02 | 임클론 시스템즈 인코포레이티드 | 항-egfr 항체의 동결건조 제제 |
MX2009006199A (es) | 2006-12-11 | 2009-06-22 | Hoffmann La Roche | Formulacion parenteral de anticuerpos abeta. |
CN101199483B (zh) | 2006-12-14 | 2011-01-26 | 上海中信国健药业股份有限公司 | 一种稳定的抗her2人源化抗体制剂 |
UY30838A1 (es) * | 2006-12-26 | 2008-07-31 | Centro Inmunologia Molecular | Composicion farmacéutica que comprende un anticuerpo monoclonal anti cd6 utilizado en el diagnostico y tratamiento de la artritis reumatoide |
MY154819A (en) | 2006-12-26 | 2015-07-31 | Centro Inmunologia Molecular | Pharmaceutical compositions with capacity to induce adoptosis in tumor cells for the diagnosis and treatment of the b-cell chroniclymphocytic leukemia |
AU2008204901A1 (en) | 2007-01-09 | 2008-07-17 | Wyeth | Anti-IL-13 antibody formulations and uses thereof |
KR20100014568A (ko) | 2007-02-28 | 2010-02-10 | 쉐링 코포레이션 | 가공된 항-il-23r 항체 |
US20090208492A1 (en) | 2007-06-14 | 2009-08-20 | Elan Pharmaceuticals, Inc. | Lyophilized Immunoglobulin Formulations and Methods of Preparation |
WO2009002521A2 (en) | 2007-06-25 | 2008-12-31 | Amgen Inc. | Compositions of specific binding agents to hepatocyte growth factor |
WO2009037190A2 (en) | 2007-09-21 | 2009-03-26 | F. Hoffmann-La Roche Ag | Pharmaceutical formulation for il-ir antibody |
BRPI0822447A2 (pt) | 2008-03-14 | 2015-06-16 | Biocon Ltd | Anticorpo monoclonal e método do mesmo |
EP2356146A1 (en) | 2008-11-07 | 2011-08-17 | Fabrus Llc | Anti-dll4 antibodies and uses thereof |
PT3721904T (pt) | 2009-11-20 | 2021-11-15 | Biocon Ltd | Formulações de anticorpo t1h |
CN102559636B (zh) | 2011-12-30 | 2014-03-12 | 百泰生物药业有限公司 | 用于白血病和自身免疫疾病的抗体融合蛋白及其制备方法 |
KR102062784B1 (ko) | 2013-07-23 | 2020-01-07 | 바이오콘 리미티드 | 단백질 내 푸코실화 수준을 제어하는 방법 |
NZ746944A (en) | 2013-07-23 | 2021-07-30 | Biocon Ltd | Use of a cd6 binding partner and method based thereon |
WO2017218750A1 (en) | 2016-06-15 | 2017-12-21 | The Cleveland Clinic Foundation | Novel anti-cd6 antibodies for treating t-cell mediated conditions |
AU2017345390A1 (en) | 2016-10-18 | 2019-05-02 | Biocon Limited | Use of itolizumab to reduce phosphorylation of CD6 |
DK3529274T3 (da) | 2016-10-21 | 2024-06-17 | Biocon Ltd | Monoklonalt antistof og fremgangsmåde til anvendelse til behandling af lupus |
US11198851B2 (en) | 2016-10-28 | 2021-12-14 | Inserm (Institut National De La Sante Et De La Rechere Medicale) | Ex vivo generation of γδ Foxp3+ regulatory T cells and therapeutic uses thereof |
EP3759140A1 (en) | 2018-02-27 | 2021-01-06 | Equillium, Inc. | Anti cd6 antibodies for treating severe asthma |
BR112021016967A2 (pt) | 2019-02-26 | 2021-11-23 | Equillium Inc | Composições de anticorpo anti-cd6 e métodos para tratar lúpus |
US20230151107A1 (en) | 2020-04-04 | 2023-05-18 | Biocon Limited | Anti-cd6 antibody compositions and methods for treating and reducing negative effects of a coronavirus including covid-19 |
CA3201076A1 (en) | 2020-12-04 | 2022-06-09 | Stephen Connelly | Methods of selectively targeting cd6 high cells and decreasing activity of t eff cells |
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