PL2970272T3 - Inhibitory glikozydazowe - Google Patents
Inhibitory glikozydazoweInfo
- Publication number
- PL2970272T3 PL2970272T3 PL14724185T PL14724185T PL2970272T3 PL 2970272 T3 PL2970272 T3 PL 2970272T3 PL 14724185 T PL14724185 T PL 14724185T PL 14724185 T PL14724185 T PL 14724185T PL 2970272 T3 PL2970272 T3 PL 2970272T3
- Authority
- PL
- Poland
- Prior art keywords
- glycosidase inhibitors
- glycosidase
- inhibitors
- Prior art date
Links
- 239000003316 glycosidase inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Psychology (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Physical Education & Sports Medicine (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361782353P | 2013-03-14 | 2013-03-14 | |
US201361817493P | 2013-04-30 | 2013-04-30 | |
EP14724185.5A EP2970272B1 (en) | 2013-03-14 | 2014-03-10 | Glycosidase inhibitors |
PCT/US2014/022630 WO2014159234A1 (en) | 2013-03-14 | 2014-03-10 | Glycosidase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2970272T3 true PL2970272T3 (pl) | 2019-09-30 |
Family
ID=50729762
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL14724185T PL2970272T3 (pl) | 2013-03-14 | 2014-03-10 | Inhibitory glikozydazowe |
Country Status (17)
Country | Link |
---|---|
US (2) | US9879001B2 (pl) |
EP (1) | EP2970272B1 (pl) |
JP (1) | JP6360147B2 (pl) |
CN (1) | CN105143222B (pl) |
AU (1) | AU2014241065B2 (pl) |
CA (1) | CA2899088C (pl) |
DK (1) | DK2970272T3 (pl) |
ES (1) | ES2723883T3 (pl) |
HR (1) | HRP20190857T1 (pl) |
HU (1) | HUE043398T2 (pl) |
IL (1) | IL241512B (pl) |
LT (1) | LT2970272T (pl) |
PL (1) | PL2970272T3 (pl) |
PT (1) | PT2970272T (pl) |
RS (1) | RS58768B1 (pl) |
SI (1) | SI2970272T1 (pl) |
WO (1) | WO2014159234A1 (pl) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR112017003658B1 (pt) * | 2014-08-28 | 2022-12-06 | Asceneuron Sa | Composto, mistura, método para inibição de uma glicosidase, e, composição farmacêutica |
EP3389658B1 (en) * | 2015-12-18 | 2020-11-25 | Merck Sharp & Dohme Corp. | Glycosidase inhibitors and uses thereof |
WO2017139975A1 (en) * | 2016-02-19 | 2017-08-24 | Huiru Wang | Antibodies against n-acetylglucosamine and n-acetyl-galactosamine |
WO2017144633A1 (en) | 2016-02-25 | 2017-08-31 | Asceneuron S. A. | Glycosidase inhibitors |
US10696668B2 (en) | 2016-02-25 | 2020-06-30 | Asceneuron Sa | Acid addition salts of piperazine derivatives |
US11261183B2 (en) | 2016-02-25 | 2022-03-01 | Asceneuron Sa | Sulfoximine glycosidase inhibitors |
BR112018017213A2 (pt) * | 2016-02-25 | 2019-01-02 | Asceneuron Sa | processo para separação dos enantiômeros de um composto, base livre, composto, e, sal. |
EP3419972B1 (en) | 2016-02-25 | 2023-07-26 | Asceneuron SA | Glycosidase inhibitors |
WO2018109198A1 (en) * | 2016-12-16 | 2018-06-21 | Janssen Pharmaceutica Nv | Bicyclic oga inhibitor compounds |
JP2020503298A (ja) * | 2016-12-16 | 2020-01-30 | ヤンセン ファーマシューティカ エヌ.ベー. | 単環式oga阻害剤化合物 |
AR110747A1 (es) * | 2017-01-27 | 2019-05-02 | Lilly Co Eli | Compuestos de 5-metil-1,2,4-oxadiazol-3-ilo |
SG11201907774VA (en) * | 2017-02-24 | 2019-09-27 | Asceneuron S A | Sulfoximine glycosidase inhibitors |
EP3585790A1 (en) * | 2017-02-27 | 2020-01-01 | Janssen Pharmaceutica NV | [1,2,4]-triazolo [1,5-a]-pyrimidinyl derivatives substituted with piperidine, morpholine or piperazine as oga inhibitors |
AR111693A1 (es) | 2017-05-25 | 2019-08-07 | Lilly Co Eli | Compuestos de 5-metil-1,3,4-oxadiazol-2-ilo con actividad inhibitoria de oga |
US11213525B2 (en) | 2017-08-24 | 2022-01-04 | Asceneuron Sa | Linear glycosidase inhibitors |
ES2942211T3 (es) * | 2018-03-14 | 2023-05-30 | Biogen Ma Inc | Inhibidores de la O-glucoproteína-2-acetamido-2-desoxi-3-D-glucopiranosidasa |
US11459324B2 (en) | 2018-03-14 | 2022-10-04 | Biogen Ma Inc. | O-glycoprotein-2-acetamido-2-deoxy-3-D-glycopyranosidase inhibitors |
TWI726329B (zh) | 2018-06-22 | 2021-05-01 | 美商美國禮來大藥廠 | 2,3-二氫呋喃并[2,3-b]吡啶化合物 |
CA3108158C (en) | 2018-07-31 | 2023-05-16 | Eli Lilly And Company | 5-methyl-4-fluoro-thiazol-2-yl compounds |
EP3829634A1 (en) * | 2018-07-31 | 2021-06-09 | Eli Lilly and Company | Combination therapy |
WO2020039028A1 (en) * | 2018-08-22 | 2020-02-27 | Asceneuron S. A. | Tetrahydro-benzoazepine glycosidase inhibitors |
US12016852B2 (en) | 2018-08-22 | 2024-06-25 | Asceneuron Sa | Pyrrolidine glycosidase inhibitors |
WO2020039029A1 (en) * | 2018-08-22 | 2020-02-27 | Asceneuron S. A. | Spiro compounds as glycosidase inhibitors |
UY38376A (es) * | 2018-09-19 | 2020-04-30 | Biogen Ma Inc | Inhibidores de o-glicoproteína-2-acetamido-2-desoxi-3-d-glucopiranosidasa |
TWI716107B (zh) | 2018-09-26 | 2021-01-11 | 美商美國禮來大藥廠 | 6-氟-2-甲基苯并[d]噻唑-5-基化合物 |
CN114929709A (zh) * | 2019-10-29 | 2022-08-19 | 比奥根Ma公司 | 螺环o-糖蛋白-2-乙酰胺基-2-脱氧-3-d-吡喃葡萄糖苷酶抑制剂 |
WO2021094312A1 (en) | 2019-11-11 | 2021-05-20 | Janssen Pharmaceutica Nv | Pyrrolidine and bicycloheteroaryl containing oga inhibitor compounds |
WO2021110656A1 (en) | 2019-12-02 | 2021-06-10 | Janssen Pharmaceutica Nv | Oga inhibitor compounds |
WO2021123291A1 (en) | 2019-12-18 | 2021-06-24 | Janssen Pharmaceutica Nv | Oga inhibitor compounds |
AU2020409728A1 (en) | 2019-12-18 | 2022-08-11 | Janssen Pharmaceutica Nv | OGA inhibitor compounds |
JP2023507180A (ja) | 2019-12-18 | 2023-02-21 | ヤンセン ファーマシューティカ エヌ.ベー. | Oga阻害剤化合物 |
CN112480018B (zh) * | 2020-11-30 | 2023-06-20 | 中国药科大学 | 一种trpv3小分子变构抑制剂及其制备方法 |
IL312045A (en) | 2021-10-22 | 2024-06-01 | Lilly Co Eli | Combination therapy with O-GLCNACASE (OGA) inhibitors. |
WO2024047185A1 (en) * | 2022-08-31 | 2024-03-07 | Janssen Pharmaceutica Nv | Mass spectroscopy assay for detecting o-beta-linked n-acetylglucosaminylated tau peptides |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT77428B (fr) * | 1982-10-05 | 1986-02-27 | Cortial | Procede pour preparer de nouvelles amino-2-substitue-5-oxazoli-nes-2 et des compositions les contenant |
FR2533923A1 (fr) * | 1982-10-05 | 1984-04-06 | Cortial | Nouvelles n-(aminomethyl-5 oxazolin-2 yl-2) n'-phenylurees, leur methode de preparation ainsi que leur application therapeutique |
US4600025A (en) | 1982-11-18 | 1986-07-15 | Grigg Ronald E | Smoking products comprising nicotine substitutes |
WO2004002481A1 (en) | 2002-06-27 | 2004-01-08 | Novo Nordisk A/S | Aryl carbonyl derivatives as therapeutic agents |
RU2340605C2 (ru) * | 2002-06-27 | 2008-12-10 | Ново Нордиск А/С | Арилкарбонильные производные в качестве терапевтических средств |
OA12937A (en) * | 2002-10-09 | 2006-10-13 | Pfizer Prod Inc | Thiazole compounds for the treatment of neurodegenerative disorders. |
BRPI0506662B8 (pt) * | 2004-01-06 | 2021-05-25 | Novo Nordisk As | compostos ativadores de glucoquinase |
JP2009500377A (ja) | 2005-07-08 | 2009-01-08 | ノボ・ノルデイスク・エー/エス | ジシクロアルキルウレア型グルコキナーゼ活性化剤 |
JP5380293B2 (ja) | 2006-08-31 | 2014-01-08 | サイモン・フレーザー・ユニバーシティ | 選択的グリコシダーゼ阻害剤およびその使用 |
US8148369B2 (en) | 2007-05-10 | 2012-04-03 | Janssen Pharmaceutica Nv | Fused pyrazine compounds useful for the treatment of degenerative and inflammatory diseases |
JP2011507910A (ja) | 2007-12-21 | 2011-03-10 | ユニバーシティー オブ ロチェスター | 真核生物の寿命を変更するための方法 |
US7863291B2 (en) | 2008-04-23 | 2011-01-04 | Bristol-Myers Squibb Company | Quinuclidine compounds as alpha-7 nicotinic acetylcholine receptor ligands |
KR20110128908A (ko) * | 2009-03-02 | 2011-11-30 | 서트리스 파마슈티컬즈, 인코포레이티드 | 시르투인 조절제로서의 8-치환된 퀴놀린 및 관련 유사체 |
US20100240720A1 (en) | 2009-03-20 | 2010-09-23 | Burnham Institute For Medical Research | Allosteric jnk inhibitors |
JP2010270034A (ja) * | 2009-05-20 | 2010-12-02 | Sumitomo Chemical Co Ltd | アミド化合物並びにその植物病害防除用途 |
CN103435606A (zh) * | 2013-08-22 | 2013-12-11 | 中国药科大学 | CDK2与GSK3β双重抑制剂及用途 |
-
2014
- 2014-03-10 CA CA2899088A patent/CA2899088C/en active Active
- 2014-03-10 LT LTEP14724185.5T patent/LT2970272T/lt unknown
- 2014-03-10 DK DK14724185.5T patent/DK2970272T3/en active
- 2014-03-10 ES ES14724185T patent/ES2723883T3/es active Active
- 2014-03-10 SI SI201431216T patent/SI2970272T1/sl unknown
- 2014-03-10 EP EP14724185.5A patent/EP2970272B1/en active Active
- 2014-03-10 AU AU2014241065A patent/AU2014241065B2/en active Active
- 2014-03-10 PT PT14724185T patent/PT2970272T/pt unknown
- 2014-03-10 HU HUE14724185A patent/HUE043398T2/hu unknown
- 2014-03-10 WO PCT/US2014/022630 patent/WO2014159234A1/en active Application Filing
- 2014-03-10 US US14/775,134 patent/US9879001B2/en active Active
- 2014-03-10 PL PL14724185T patent/PL2970272T3/pl unknown
- 2014-03-10 CN CN201480014258.5A patent/CN105143222B/zh active Active
- 2014-03-10 RS RS20190638A patent/RS58768B1/sr unknown
- 2014-03-10 JP JP2016501020A patent/JP6360147B2/ja active Active
-
2015
- 2015-09-10 IL IL241512A patent/IL241512B/en active IP Right Grant
-
2017
- 2017-12-04 US US15/830,675 patent/US10301299B2/en active Active
-
2019
- 2019-05-09 HR HRP20190857TT patent/HRP20190857T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
WO2014159234A1 (en) | 2014-10-02 |
EP2970272A1 (en) | 2016-01-20 |
IL241512A0 (en) | 2015-11-30 |
HRP20190857T1 (hr) | 2019-07-12 |
US10301299B2 (en) | 2019-05-28 |
EP2970272B1 (en) | 2019-02-27 |
CN105143222B (zh) | 2018-02-02 |
RS58768B1 (sr) | 2019-06-28 |
DK2970272T3 (en) | 2019-04-23 |
US9879001B2 (en) | 2018-01-30 |
CA2899088C (en) | 2022-12-20 |
CN105143222A (zh) | 2015-12-09 |
CA2899088A1 (en) | 2014-10-02 |
PT2970272T (pt) | 2019-06-05 |
AU2014241065B2 (en) | 2017-08-31 |
JP6360147B2 (ja) | 2018-07-18 |
AU2014241065A1 (en) | 2015-08-13 |
US20160031871A1 (en) | 2016-02-04 |
LT2970272T (lt) | 2019-04-25 |
IL241512B (en) | 2020-08-31 |
SI2970272T1 (sl) | 2019-06-28 |
ES2723883T3 (es) | 2019-09-03 |
HUE043398T2 (hu) | 2019-08-28 |
JP2016517411A (ja) | 2016-06-16 |
US20180093977A1 (en) | 2018-04-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUE043398T2 (hu) | Glikozidáz inhibítorok | |
HK1212696A1 (zh) | 抑制劑 | |
HK1220459A1 (zh) | 激酶抑制劑 | |
EP2970340A4 (en) | BETA-Lactamase INHIBITORS | |
EP2943204A4 (en) | BETA-Lactamase INHIBITORS | |
EP2978425A4 (en) | XIA FACTOR INHIBITORS | |
EP2948450A4 (en) | METALLOENZYMINHIBITORVERBINDUNGEN | |
IL239827A0 (en) | Deoxyuridine triphosphatase inhibitors | |
HK1211578A1 (en) | Amidoimidazopyridazines as mknk-1 kinase inhibitors mknk-1 | |
IL265496A (en) | bace1 inhibitors | |
HK1216531A1 (zh) | 新的抑制劑 | |
IL245442A0 (en) | gsk–3 inhibitors | |
HK1219104A1 (zh) | 激酶抑制劑 | |
GB201317609D0 (en) | Inhibitor compounds | |
HK1223367A1 (zh) | 新型 抑制劑 | |
HK1222339A1 (zh) | 金屬-β-內酰胺酶的抑制劑 | |
EP2980089A4 (en) | HETEROCYCLIC CONNECTION | |
GB201313664D0 (en) | Bcl-3 inhibitors | |
HK1217950A1 (zh) | 新型 抑制劑 | |
GB201305503D0 (en) | Inhibitor | |
GB201321328D0 (en) | Inhibitor compounds | |
GB201307155D0 (en) | Kinase inhibitors | |
GB201310577D0 (en) | Secnidazole |