PL2838907T3 - Aminosteroidy do leczenia choroby związanej z PTP1B - Google Patents

Aminosteroidy do leczenia choroby związanej z PTP1B

Info

Publication number: PL2838907T3
Authority: PL; Poland
Prior art keywords: aminosteroids; treatment; associated disease; ptp1b; ptp1b associated
Prior art date: 2012-04-20

Application number

PL13721176T

Other languages

English (en)

Inventor

Michael Mclane

Inez Ruiz-White

W. Lee Maloy

Henry R. Wolfe

Original Assignee

Ohr Pharmaceutical, Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-04-20

Filing date

2013-04-19

Publication date

2019-12-31

2013-04-19 Application filed by Ohr Pharmaceutical, Inc. filed Critical Ohr Pharmaceutical, Inc.

2019-12-31 Publication of PL2838907T3 publication Critical patent/PL2838907T3/pl

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Obesity (AREA)
Hematology (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Child & Adolescent Psychology (AREA)
Pulmonology (AREA)
Gastroenterology & Hepatology (AREA)
Emergency Medicine (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

PL13721176T 2012-04-20 2013-04-19 Aminosteroidy do leczenia choroby związanej z PTP1B PL2838907T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201261636252P	2012-04-20	2012-04-20
EP13721176.9A EP2838907B1 (en)	2012-04-20	2013-04-19	Aminosteroids for the treatment of a ptp1b associated disease
PCT/US2013/037330 WO2013158970A2 (en)	2012-04-20	2013-04-19	Aminosteroids for the treatment of a ptp1b associated disease

Publications (1)

Publication Number	Publication Date
PL2838907T3 true PL2838907T3 (pl)	2019-12-31

Family

ID=48325893

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL13721176T PL2838907T3 (pl)	2012-04-20	2013-04-19	Aminosteroidy do leczenia choroby związanej z PTP1B

Country Status (16)

Country	Link
US (5)	US9546194B2 (pl)
EP (2)	EP2838907B1 (pl)
JP (4)	JP6165843B2 (pl)
KR (3)	KR20150003798A (pl)
AU (3)	AU2013249111B2 (pl)
CA (1)	CA2870671C (pl)
DK (1)	DK2838907T3 (pl)
ES (1)	ES2736310T3 (pl)
HK (1)	HK1205516A1 (pl)
HR (1)	HRP20191348T1 (pl)
HU (1)	HUE044769T2 (pl)
MX (2)	MX367255B (pl)
PL (1)	PL2838907T3 (pl)
PT (1)	PT2838907T (pl)
TR (1)	TR201911039T4 (pl)
WO (1)	WO2013158970A2 (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TR201911039T4 (tr) *	2012-04-20	2019-08-21	Ohr Pharmaceutical Inc	Ptp1b ile ilişkili bir hastalığın tedavisine yönelik aminosteroidler.
US10040817B2 (en)	2013-10-03	2018-08-07	Enterin Laboratories, Inc.	Methods and compositions for stimulation of the intestinal enteroendocrine system for treating diseases or conditions related to the same
GB201700567D0 (en)	2017-01-12	2017-03-01	Genagon Therapeutics Ab	Therapeutic agents
WO2019050903A1 (en) *	2017-09-08	2019-03-14	Enterin Laboratories, Inc.	METHODS OF TREATING SLEEP DISORDERS, SLEEP DISTURBANCES AND ASSOCIATED SYMPTOMS USING AMINOSTEROL COMPOSITIONS
CN107802626B (zh) *	2017-10-11	2020-01-21	南昌大学	降血糖组合物及其制备方法、用途
CN111801102B (zh) *	2017-11-06	2024-05-28	冷泉港实验室	用于形成含铜络合物的方法和组合物及其用途
AU2019242557A1 (en) *	2018-03-27	2020-10-15	Enterin, Inc.	Methods and compositions for treating hallucinations and conditions related to the same
CA3110049A1 (en) *	2018-07-20	2020-01-23	Cold Spring Harbor Laboratory	(pyridinylmethyl)butanediamine derivatives that chelate copper
EP4007765A4 (en) *	2019-08-02	2023-08-23	Enterin, Inc.	HUMAN SQUALAMIN DERIVATIVES, COMPOSITIONS CONTAINING THEM, AND METHODS OF USE THEREOF
CA3149479A1 (en) *	2019-08-02	2021-02-11	Enterin, Inc.	Human aminosterol ent-03 compounds, related compositions comprising the same, and methods of using the same
WO2023230593A1 (en)	2022-05-27	2023-11-30	Cold Spring Harbor Laboratory	Ptp1b inhibitors for treating lung injury

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2403683A (en) *	1942-04-25	1946-07-09	Relchstein Tadeus	Compounds of the cyclopentanopolyhydrophenanthrene series and process of making same
US3636210A (en) *	1968-02-02	1972-01-18	Merck & Co Inc	Cholanic acid and cholenic acid compositions and method of treatment
JPS60181096A (ja) *	1984-02-28	1985-09-14	Tokyo Tanabe Co Ltd	胆汁酸の精製方法
IT1255450B (it) *	1992-06-30	1995-10-31	Montefarmaco Spa	Uso di acidi biliari come agenti antivirali
AU6392894A (en) *	1993-02-26	1994-09-14	Magainin Pharmaceuticals, Inc.	Chemical synthesis of squalamine
CA2157594A1 (en)	1993-03-10	1994-09-15	Leah L. Frye	Steroid derivatives, pharmaceutical compositions containing them, and their use as antibiotics or disinfectants
US5856535A (en)	1994-08-18	1999-01-05	Magainin Pharmaceuticals, Inc.	Aminosterol ester compounds
US5792635A (en)	1995-06-07	1998-08-11	Magainin Pharmaceuticals, Inc.	Method of inhibiting the sodium/proton exchanger NHE3 and method of inhibiting growth by administering squalamine
CA2223910C (en) *	1995-06-07	2008-09-16	Magainin Pharmaceuticals Inc.	Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (nhe), pharmaceutical methods and compositions employing such inhibitors, and processes for evaluating the nhe-inhibitory efficacy of compounds
US7410959B1 (en) *	2000-07-13	2008-08-12	Genaera Corporation	Therapeutic uses for aminosterol compounds
AU7476800A (en)	1999-09-10	2001-04-10	Novo Nordisk A/S	Method of inhibiting protein tyrosine phosphatase 1b and/or t-cell protein tyrosine phosphatase and/or other ptpases with an asp residue at position 48
AU6985300A (en)	1999-09-10	2001-04-17	Novo Nordisk A/S	Modulators of protein tyrosine phosphatases (ptpases)
JP2003509429A (ja)	1999-09-10	2003-03-11	ノボノルディスクアクティーゼルスカブ	タンパク質チロシンホスファターゼ（ｐｔｐアーゼ）のモジュレーター
US7074778B2 (en) *	1999-12-09	2006-07-11	Genaera Corporation	Asthma associated factors as targets for treating atopic allergies including asthma and related disorders
ATE433457T1 (de) *	2002-12-24	2009-06-15	Univ British Columbia	Angiogen-wirkende trisulfat steroide und deren verwendung
JP2006165843A (ja) *	2004-12-06	2006-06-22	Matsushita Electric Ind Co Ltd	画像処理装置
US20080058300A1 (en)	2006-04-21	2008-03-06	Mclane Michael	Induction of weight loss and the selective inhibition of PTP1B
CA2985271A1 (en) *	2007-09-06	2009-03-12	Ohr Pharmaceutical, Inc.	A method for treating diabetes
KR101260221B1 (ko) *	2011-12-01	2013-05-06	주식회사 엘지화학	마스크
TR201911039T4 (tr)	2012-04-20	2019-08-21	Ohr Pharmaceutical Inc	Ptp1b ile ilişkili bir hastalığın tedavisine yönelik aminosteroidler.

2013
- 2013-04-19 TR TR2019/11039T patent/TR201911039T4/tr unknown
- 2013-04-19 CA CA2870671A patent/CA2870671C/en active Active
- 2013-04-19 PT PT13721176T patent/PT2838907T/pt unknown
- 2013-04-19 US US14/394,789 patent/US9546194B2/en active Active
- 2013-04-19 WO PCT/US2013/037330 patent/WO2013158970A2/en active Application Filing
- 2013-04-19 MX MX2014012619A patent/MX367255B/es active IP Right Grant
- 2013-04-19 PL PL13721176T patent/PL2838907T3/pl unknown
- 2013-04-19 KR KR1020147031485A patent/KR20150003798A/ko active Application Filing
- 2013-04-19 DK DK13721176.9T patent/DK2838907T3/da active
- 2013-04-19 EP EP13721176.9A patent/EP2838907B1/en active Active
- 2013-04-19 KR KR1020167019758A patent/KR101963312B1/ko active IP Right Grant
- 2013-04-19 EP EP19175554.5A patent/EP3556765B1/en active Active
- 2013-04-19 ES ES13721176T patent/ES2736310T3/es active Active
- 2013-04-19 HU HUE13721176 patent/HUE044769T2/hu unknown
- 2013-04-19 KR KR1020197008179A patent/KR102057812B1/ko active IP Right Grant
- 2013-04-19 AU AU2013249111A patent/AU2013249111B2/en active Active
- 2013-04-19 JP JP2015507213A patent/JP6165843B2/ja active Active
2014
- 2014-10-17 MX MX2019009539A patent/MX2019009539A/es unknown
2015
- 2015-06-25 HK HK15106046.4A patent/HK1205516A1/xx unknown
2016
- 2016-10-06 US US15/286,646 patent/US20170129914A1/en not_active Abandoned
2017
- 2017-05-02 JP JP2017091568A patent/JP6457010B2/ja active Active
2018
- 2018-10-31 AU AU2018256561A patent/AU2018256561B2/en active Active
- 2018-12-19 JP JP2018237492A patent/JP2019059781A/ja not_active Withdrawn
2019
- 2019-03-12 US US16/299,872 patent/US10556923B2/en active Active
- 2019-07-25 HR HRP20191348TT patent/HRP20191348T1/hr unknown
2020
- 2020-01-30 US US16/777,253 patent/US11434257B2/en active Active
- 2020-06-05 AU AU2020203736A patent/AU2020203736B2/en active Active
2021
- 2021-01-25 JP JP2021009651A patent/JP2021073250A/ja active Pending
2022
- 2022-07-29 US US17/877,498 patent/US20230203088A1/en not_active Abandoned

Also Published As

Publication number	Publication date
KR20190034685A (ko)	2019-04-02
AU2013249111B2 (en)	2018-08-09
MX367255B (es)	2019-08-12
KR20150003798A (ko)	2015-01-09
JP2017178951A (ja)	2017-10-05
MX2014012619A (es)	2015-01-15
US9546194B2 (en)	2017-01-17
EP3556765B1 (en)	2022-02-23
US20200270300A1 (en)	2020-08-27
CA2870671C (en)	2020-05-12
KR20160091435A (ko)	2016-08-02
JP6165843B2 (ja)	2017-07-19
ES2736310T3 (es)	2019-12-27
KR102057812B1 (ko)	2019-12-19
JP6457010B2 (ja)	2019-01-23
AU2020203736A1 (en)	2020-06-25
US20170129914A1 (en)	2017-05-11
WO2013158970A3 (en)	2013-12-12
EP2838907A2 (en)	2015-02-25
US20230203088A1 (en)	2023-06-29
KR101963312B1 (ko)	2019-03-28
US20190202858A1 (en)	2019-07-04
EP2838907B1 (en)	2019-05-22
PT2838907T (pt)	2019-08-05
AU2013249111A1 (en)	2014-11-06
WO2013158970A2 (en)	2013-10-24
TR201911039T4 (tr)	2019-08-21
EP3556765A1 (en)	2019-10-23
MX2019009539A (es)	2019-09-26
AU2020203736B2 (en)	2021-12-02
JP2015514781A (ja)	2015-05-21
US10556923B2 (en)	2020-02-11
US11434257B2 (en)	2022-09-06
AU2018256561A1 (en)	2018-11-22
HK1205516A1 (en)	2015-12-18
JP2019059781A (ja)	2019-04-18
AU2018256561B2 (en)	2020-03-05
CA2870671A1 (en)	2013-10-24
JP2021073250A (ja)	2021-05-13
HRP20191348T1 (hr)	2019-10-18
DK2838907T3 (da)	2019-08-05
US20150099727A1 (en)	2015-04-09
HUE044769T2 (hu)	2019-11-28

Publication	Publication Date	Title
HK1205516A1 (en)	2015-12-18	Aminosteroids for the treatment of a ptp1b associated disease ptp1b
GB201120345D0 (en)	2012-01-04	Medical console
ZA201305897B (en)	2014-04-30	Combination therapy
GB201212513D0 (en)	2012-08-29	Therapeutic agents
EP2740419A4 (en)	2015-04-01	TREATMENT INSTRUMENT
GB201321559D0 (en)	2014-01-22	Diagnosis of the condition of apparatus
EP2800530A4 (en)	2015-07-01	TRANSFORMERS FOR HISTOTRIPSIA THERAPY
ZA201400120B (en)	2015-09-30	Combination therapy
EP2740420A4 (en)	2015-04-08	THERAPEUTIC TOOL
GB2508667B (en)	2015-10-07	Diagnosis of the condition of apparatus
GB201217704D0 (en)	2012-11-14	Therapeutic agents
EP2883547A4 (en)	2016-02-10	MEDICINE
EP2701744A4 (en)	2014-08-20	COMBINATION THERAPY
GB201207305D0 (en)	2012-06-13	Therapy
HK1200723A1 (en)	2015-08-14	Pharmaceutical diagnostic
GB201505622D0 (en)	2015-05-13	Patient reported outcome instrument
HK1210474A1 (en)	2016-04-22	Therapeutic bisphosphonates
IL234796B (en)	2018-02-28	Compounds for the treatment of diseases related to ischemia-reperfusion
EP2704731A4 (en)	2015-02-11	TREATMENT OF AVIAN ORIGIN
GB201106981D0 (en)	2011-06-08	Compounds for the treatment of clostridium difficle-associated disease
GB201114226D0 (en)	2011-10-05	Combination therapy
GB201223021D0 (en)	2013-02-06	Therapeutic agents
IL222594A0 (en)	2012-12-31	Combined treatment utilizing vb-201
GB201212512D0 (en)	2012-08-29	Therapeutic agents
GB201210233D0 (en)	2012-07-25	Therapeutic agents