PL2563771T3 - Związki inhibitora metaloenzymu - Google Patents
Związki inhibitora metaloenzymuInfo
- Publication number
- PL2563771T3 PL2563771T3 PL11772772T PL11772772T PL2563771T3 PL 2563771 T3 PL2563771 T3 PL 2563771T3 PL 11772772 T PL11772772 T PL 11772772T PL 11772772 T PL11772772 T PL 11772772T PL 2563771 T3 PL2563771 T3 PL 2563771T3
- Authority
- PL
- Poland
- Prior art keywords
- inhibitor compounds
- metalloenzyme inhibitor
- metalloenzyme
- compounds
- inhibitor
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32766310P | 2010-04-24 | 2010-04-24 | |
| PCT/US2011/033597 WO2011133875A2 (en) | 2010-04-24 | 2011-04-22 | Metalloenzyme inhibitor compounds |
| EP11772772.7A EP2563771B1 (en) | 2010-04-24 | 2011-04-22 | Metalloenzyme inhibitor compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2563771T3 true PL2563771T3 (pl) | 2016-06-30 |
Family
ID=44834829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL11772772T PL2563771T3 (pl) | 2010-04-24 | 2011-04-22 | Związki inhibitora metaloenzymu |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US8236962B2 (pl) |
| EP (1) | EP2563771B1 (pl) |
| JP (2) | JP5266430B2 (pl) |
| KR (1) | KR101379370B1 (pl) |
| CN (1) | CN103097374B (pl) |
| AU (1) | AU2011242562B2 (pl) |
| BR (1) | BR112012027308B1 (pl) |
| CA (2) | CA2792950C (pl) |
| CY (1) | CY1117678T1 (pl) |
| DK (1) | DK2563771T3 (pl) |
| EA (1) | EA024341B1 (pl) |
| ES (1) | ES2563319T3 (pl) |
| HR (1) | HRP20160172T1 (pl) |
| HU (1) | HUE026474T2 (pl) |
| PL (1) | PL2563771T3 (pl) |
| PT (1) | PT2563771E (pl) |
| RS (1) | RS55010B1 (pl) |
| SI (1) | SI2563771T1 (pl) |
| TW (1) | TWI578987B (pl) |
| WO (1) | WO2011133875A2 (pl) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3153020T3 (en) | 2009-10-07 | 2019-03-25 | Dow Agrosciences Llc | SYNERGISTIC FUNGICIDE MIXTURES FOR FERTILIZER IN GRAIN PLANTS |
| ES2563319T3 (es) * | 2010-04-24 | 2016-03-14 | Viamet Pharmaceuticals, Inc. | Compuestos inhibidores de metaloenzimas |
| AU2011285724B2 (en) | 2010-08-04 | 2015-01-22 | Pellficure Pharmaceuticals, Inc. | Combination therapy for the treatment of prostate carcinoma |
| BR122020013521B1 (pt) * | 2011-06-19 | 2021-05-25 | Viamet Pharmaceuticals (NC), Inc | compostos inibidores de metaloenzima |
| AU2012273166A1 (en) | 2011-06-19 | 2014-01-23 | Viamet Pharmaceuticals (NC), Inc. | Metalloenzyme inhibitor compounds |
| US8883797B2 (en) | 2011-06-23 | 2014-11-11 | Viamet Pharmaceuticals, Inc. | Metalloenzyme inhibitor compounds |
| BR112014013963B1 (pt) * | 2011-12-11 | 2021-06-22 | Nqp 1598, Ltd | Compostos inibidores de metaloenzimas, composições compreendendo os ditos compostos, uso terapêutico dos mesmos e métodos para inibir a atividade de metaloenzimas e para tratar ou prevenir o crescimento de fungos em plantas |
| IN2014DN06792A (pl) * | 2012-01-20 | 2015-05-22 | Viamet Pharmaceuticals Inc | |
| CA2861341A1 (en) * | 2012-01-20 | 2013-07-25 | Viamet Pharmaceuticals, Inc. | Metalloenzyme inhibitor compounds against fungal infection induced plant diseases and method of use thereof |
| TWI646088B (zh) * | 2012-03-16 | 2019-01-01 | 維愛美製藥公司 | 金屬酶抑制劑化合物 |
| TWI654180B (zh) | 2012-06-29 | 2019-03-21 | 美商艾佛艾姆希公司 | 殺真菌之雜環羧醯胺 |
| EP2894981B1 (en) * | 2012-09-12 | 2019-12-04 | Dow AgroSciences LLC | Metalloenzyme inhibitor compounds |
| LT2938191T (lt) | 2012-12-28 | 2018-05-10 | Dow Agrosciences Llc | Sinergistiniai fungicidiniai mišiniai, skirti grybelių kontrolei javuose |
| RU2015131840A (ru) | 2012-12-31 | 2017-02-03 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Макроциклические пиколинамиды в качестве фунгицидов |
| EP2951167B1 (en) * | 2013-02-04 | 2017-01-25 | Syngenta Participations AG | Novel microbiocides |
| AU2014241816B9 (en) | 2013-03-14 | 2019-02-14 | Pellficure Pharmaceuticals Inc. | Novel therapy for prostate carcinoma |
| CA2915054A1 (en) * | 2013-06-12 | 2014-12-18 | Viamet Pharmaceuticals, Inc. | Metalloenzyme inhibitor compounds |
| EP3086640A4 (en) | 2013-12-26 | 2017-06-21 | Dow AgroSciences LLC | Macrocyclic picolinamides as fungicides |
| CN106061256A (zh) | 2013-12-26 | 2016-10-26 | 美国陶氏益农公司 | 具有杀真菌活性的大环吡啶酰胺化合物 |
| EA201691648A1 (ru) | 2014-03-19 | 2017-01-30 | Ваймет Фармасьютикалс, Инк. | Способ получения противогрибковых соединений |
| MX365494B (es) * | 2014-03-19 | 2019-06-05 | Us Health | Procedimiento de compuesto antifungico. |
| EP3119756B9 (en) | 2014-03-19 | 2021-08-25 | Dow AgroSciences LLC | 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-substituted-pyridin-2-yl)-3-(1h-tetrazol-1-yl)propan-2-ols and processes for their preparation |
| WO2015143142A1 (en) | 2014-03-19 | 2015-09-24 | Viamet Pharmaceuticals, Inc. | Antifungal compound process |
| AU2015231220B2 (en) * | 2014-03-19 | 2019-04-04 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Antifungal compound process |
| US9802914B2 (en) | 2014-03-19 | 2017-10-31 | Viamet Pharmaceuticals, Inc. | Antifungal compound process |
| WO2015143180A1 (en) * | 2014-03-19 | 2015-09-24 | Viamet Pharmaceuticals, Inc. | Antifungal compound process |
| WO2015143184A1 (en) | 2014-03-19 | 2015-09-24 | Viamet Pharmaceuticals, Inc. | Antifungal compound process |
| US9981943B2 (en) | 2014-03-19 | 2018-05-29 | Mycovia Pharmaceuticals, Inc. | Antifungal compound process |
| BR112016021257B1 (pt) * | 2014-03-19 | 2021-03-02 | Viamet Pharmaceuticals (NC), Inc. | 2-(2,4- difluorofenil-1,1-diflúor-1-(5-substituído-piridin-2-il)-3- (1h-tetrazol-1-il)propan-2-óis e processos para preparação e uso dos mesmos |
| CA2945674A1 (en) * | 2014-04-15 | 2015-10-22 | Dow Agrosciences Llc | Metalloenzyme inhibitor compounds as fungicides |
| US20150322051A1 (en) | 2014-05-06 | 2015-11-12 | Dow Agrosciences Llc | Macrocyclic picolinamides as fungicides |
| JP2017525753A (ja) | 2014-06-06 | 2017-09-07 | フレクサス・バイオサイエンシーズ・インコーポレイテッドＦｌｅｘｕｓ Ｂｉｏｓｃｉｅｎｃｅｓ， Ｉｎｃ． | 免疫調節剤 |
| CN106470982A (zh) | 2014-07-08 | 2017-03-01 | 美国陶氏益农公司 | 作为杀真菌剂的大环吡啶酰胺 |
| EP3166935A4 (en) | 2014-07-08 | 2017-11-22 | Dow AgroSciences LLC | Macrocyclic picolinamides as fungicides |
| AU2015314772B2 (en) | 2014-09-12 | 2020-02-27 | Pellficure Pharmaceuticals, Inc. | Compositions and methods for treatment of prostate carcinoma |
| UY36390A (es) | 2014-11-05 | 2016-06-01 | Flexus Biosciences Inc | Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen |
| AR102537A1 (es) | 2014-11-05 | 2017-03-08 | Flexus Biosciences Inc | Agentes inmunomoduladores |
| CN107205970A (zh) | 2014-11-05 | 2017-09-26 | 弗莱塞斯生物科学公司 | 免疫调节剂 |
| MX2017008439A (es) | 2014-12-30 | 2017-10-02 | Dow Agrosciences Llc | Compuestos de picolinamida con actividad fungicida. |
| CA2971433A1 (en) | 2014-12-30 | 2016-07-07 | Dow Agrosciences Llc | Picolinamides with fungicidal activity |
| JP6767979B2 (ja) | 2014-12-30 | 2020-10-14 | ダウ アグロサイエンシィズ エルエルシー | 殺真菌性組成物 |
| RU2017126717A (ru) | 2014-12-30 | 2019-01-31 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Применение пиколинамидов в качестве фунгицидов |
| BR112017013758B1 (pt) | 2014-12-30 | 2021-11-23 | Dow Agrosciences Llc | Compostos de picolinamida com atividade fungicida |
| WO2016109257A1 (en) | 2014-12-30 | 2016-07-07 | Dow Agrosciences Llc | Use of picolinamide compounds as fungicides |
| BR112017018823A2 (pt) | 2015-03-19 | 2018-04-24 | Viamet Pharmaceuticals, Inc. | compostos antifúngicos e processos para a fabricação |
| DK3297998T3 (da) * | 2015-05-18 | 2020-03-16 | Viamet Pharmaceuticals Nc Inc | Antisvampeforbindelser |
| BR112018005198A2 (pt) | 2015-09-18 | 2018-10-09 | Vps-3, Inc. | compostos antifúngicos e processos de manufatura |
| CN108779094B (zh) * | 2015-12-30 | 2021-11-16 | Nqp 1598公司 | 金属酶抑制剂化合物 |
| US10244754B2 (en) | 2016-08-30 | 2019-04-02 | Dow Agrosciences Llc | Picolinamide N-oxide compounds with fungicidal activity |
| US10334852B2 (en) | 2016-08-30 | 2019-07-02 | Dow Agrosciences Llc | Pyrido-1,3-oxazine-2,4-dione compounds with fungicidal activity |
| WO2018044996A1 (en) | 2016-08-30 | 2018-03-08 | Dow Agrosciences Llc | Picolinamides as fungicides |
| US10172358B2 (en) | 2016-08-30 | 2019-01-08 | Dow Agrosciences Llc | Thiopicolinamide compounds with fungicidal activity |
| CA3044812A1 (en) | 2016-10-24 | 2018-05-03 | Pellficure Pharmaceuticals Inc. | Pharmaceutical compositions of 5-hydroxy-2-methylnaphthalene-1,4-dione |
| DK3559009T3 (da) | 2016-12-22 | 2021-05-03 | Calithera Biosciences Inc | Sammensætninger og metoder til inhibition af arginaseaktivitet |
| BR102018000183B1 (pt) | 2017-01-05 | 2023-04-25 | Dow Agrosciences Llc | Picolinamidas, composição para controle de um patógeno fúngico, e método para controle e prevenção de um ataque por fungos em uma planta |
| TWI774761B (zh) | 2017-05-02 | 2022-08-21 | 美商科迪華農業科技有限責任公司 | 用於穀物中的真菌防治之協同性混合物 |
| TW201842851A (zh) | 2017-05-02 | 2018-12-16 | 美商陶氏農業科學公司 | 用於穀類中的真菌防治之協同性混合物 |
| CN110996665B (zh) | 2017-05-02 | 2021-10-26 | 陶氏益农公司 | 无环吡啶酰胺化合物作为针对草坪草上的真菌病害的杀真菌剂的用途 |
| US11213031B2 (en) | 2017-11-13 | 2022-01-04 | Bayer Aktiengesellschaft | Tetrazolylpropyl derivatives and their use as fungicides |
| BR102019004480B1 (pt) | 2018-03-08 | 2023-03-28 | Dow Agrosciences Llc | Picolinamidas como fungicidas |
| BR112021006669A2 (pt) | 2018-10-15 | 2021-07-06 | Dow Agrosciences Llc | métodos para síntese de oxipicolinamidas |
| TW202140445A (zh) * | 2020-01-17 | 2021-11-01 | 大陸商上海森輝醫藥有限公司 | 四氮唑類化合物的可藥用鹽及其結晶形式、製備方法和用途 |
| WO2021188404A1 (en) | 2020-03-19 | 2021-09-23 | Assia Chemical Industries Ltd | Solid state forms of oteseconazole and process for preparation thereof |
| WO2024067784A1 (zh) * | 2022-09-30 | 2024-04-04 | 上海济煜医药科技有限公司 | 双环类化合物的无定形、结晶固体及其制备方法 |
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2011
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