PL2254887T3 - Pochodne oksazolidynonu - Google Patents

Pochodne oksazolidynonu

Info

Publication number
PL2254887T3
PL2254887T3 PL09711588T PL09711588T PL2254887T3 PL 2254887 T3 PL2254887 T3 PL 2254887T3 PL 09711588 T PL09711588 T PL 09711588T PL 09711588 T PL09711588 T PL 09711588T PL 2254887 T3 PL2254887 T3 PL 2254887T3
Authority
PL
Poland
Prior art keywords
oxazolidinone derivatives
oxazolidinone
derivatives
Prior art date
Application number
PL09711588T
Other languages
English (en)
Inventor
Christian Hubschwerlen
Georg Rueedi
Jean-Philippe Surivet
Acklin Cornelia Zumbrunn
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of PL2254887T3 publication Critical patent/PL2254887T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL09711588T 2008-02-22 2009-02-20 Pochodne oksazolidynonu PL2254887T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IB2008050651 2008-02-22
IB2008054095 2008-10-07
EP09711588.5A EP2254887B9 (en) 2008-02-22 2009-02-20 Oxazolidinone derivatives
PCT/IB2009/050702 WO2009104159A1 (en) 2008-02-22 2009-02-20 Oxazolidinone derivatives

Publications (1)

Publication Number Publication Date
PL2254887T3 true PL2254887T3 (pl) 2013-05-31

Family

ID=40578768

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09711588T PL2254887T3 (pl) 2008-02-22 2009-02-20 Pochodne oksazolidynonu

Country Status (14)

Country Link
US (1) US8349826B2 (pl)
EP (1) EP2254887B9 (pl)
JP (1) JP5404652B2 (pl)
KR (1) KR101592046B1 (pl)
CN (1) CN102015698B (pl)
AR (1) AR070458A1 (pl)
BR (1) BRPI0908208A2 (pl)
CA (1) CA2713187C (pl)
ES (1) ES2398939T3 (pl)
MX (1) MX2010008921A (pl)
PL (1) PL2254887T3 (pl)
RU (1) RU2501799C2 (pl)
TW (1) TWI429643B (pl)
WO (1) WO2009104159A1 (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200940551A (en) 2008-02-20 2009-10-01 Actelion Pharmaceuticals Ltd Azatricyclic antibiotic compounds
DK2344495T3 (en) 2008-10-07 2015-02-02 Actelion Pharmaceuticals Ltd TRICYCLIC OXAZOLIDINON ANTIBIOTIC COMPOUNDS
ES2395491T3 (es) * 2008-10-10 2013-02-13 Actelion Pharmaceuticals Ltd. 2-Benzotiofenil y 2-naftil-oxazolidinonas y sus análogos azaisósteros como agentes antibacterianos
CN102164919B (zh) * 2008-10-10 2014-04-09 埃科特莱茵药品有限公司 噁唑烷基抗生素
AR076222A1 (es) 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd Derivados 2-hidroxietil-1h-quinolin-ona y sus analogos azaisotericos con actividad antibacteriana y composiciones farmaceuticas que los contienen
US8952010B2 (en) 2011-02-07 2015-02-10 Daiichi Sankyo Company, Limited Amino group-containing pyrrolidinone derivative
WO2013021363A1 (en) 2011-08-11 2013-02-14 Actelion Pharmaceuticals Ltd Quinazoline-2,4-dione derivatives
CA2854264A1 (en) * 2011-11-08 2013-05-16 Actelion Pharmaceuticals Ltd 2-oxo-oxazolidin-3,5-diyl antibiotic derivatives
EP2785721A1 (en) 2011-11-30 2014-10-08 Actelion Pharmaceuticals Ltd. 3,7-disubstituted octahydro-2h-pyrido[4,3-e][1,3]oxazin-2-one antibiotics
WO2014024056A1 (en) 2012-08-06 2014-02-13 Daiichi Sankyo Company, Limited Pyrrolidine derivatives with antibacterial properties
US9487516B2 (en) 2013-01-09 2016-11-08 Actelion Pharmaceuticals, Ltd. Antibacterial oxadiazolone derivatives
AU2014255326B2 (en) 2013-04-16 2018-09-13 Idorsia Pharmaceuticals Ltd Antibacterial biaromatic derivatives
US20160090383A1 (en) * 2013-05-08 2016-03-31 Actelion Pharmaceuticals Ltd. Antibacterial phthalide derivatives
AR102256A1 (es) 2014-10-15 2017-02-15 Actelion Pharmaceuticals Ltd Derivados biaromáticos básicos antibacterianos con sustitución de aminoalcoxi
GB201602235D0 (en) * 2016-02-08 2016-03-23 Redx Pharma Plc Antibacterial compounds
EP3414246A1 (en) * 2016-02-08 2018-12-19 Redx Pharma PLC Antibacterial compounds
EP3413976A1 (en) * 2016-02-08 2018-12-19 Redx Pharma PLC Heterocyclic compounds, in particular 2-oxo-4,4,5,5,6,6,7,7-octahydrobenzoxazole derivatives, and their use as antibacterial compounds
TW201833120A (zh) 2017-02-17 2018-09-16 瑞士商愛杜西亞製藥有限公司 芳基噁唑啶酮抗生素化合物
US10912780B2 (en) * 2017-06-08 2021-02-09 Bugworks Research, Inc. Heterocyclic compounds useful as anti-bacterial agents and method for production thereof
ES2952989T3 (es) 2017-11-29 2023-11-07 Bugworks Res Inc Compuestos heterocíclicos antibacterianos y su síntesis
PL3774790T3 (pl) * 2018-03-28 2023-07-31 Bugworks Research, Inc. Oksazolidynonowe związki antybiotykowe oraz sposób ich wytwarzania

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GB2168696B (en) 1984-12-21 1989-01-11 Boehringer Biochemia Srl Fluoro coumarins as antilymphoedema agents
CA2012681A1 (en) * 1989-03-31 1990-09-30 Masayasu Okuhira Quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same
DE19514313A1 (de) * 1994-08-03 1996-02-08 Bayer Ag Benzoxazolyl- und Benzothiazolyloxazolidinone
DE19601265A1 (de) * 1996-01-16 1997-07-17 Bayer Ag 2-Oxo- und 2-Thio-1,2-dihydrochinolinyl-oxazolidinone
CN1163892A (zh) * 1996-01-16 1997-11-05 拜尔公司 2-氧代-和2-硫代-1,2-二氢喹啉基-噁唑烷酮类化合物
DE19604223A1 (de) * 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
WO2001030782A2 (en) 1999-10-29 2001-05-03 Syngenta Participations Ag Novel herbicides
GB0031086D0 (en) 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0101577D0 (en) 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
FR2852954B1 (fr) 2003-03-28 2006-07-14 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
EP1771456A2 (fr) * 2004-07-30 2007-04-11 Palumed SA Molecules hybrides qa ou q est une aminoquinoleine et a est un residu antibiotique, leur synthese et leurs utilisations en tant qu'agent antibacterien
TWI320783B (en) 2005-04-14 2010-02-21 Otsuka Pharma Co Ltd Heterocyclic compound
MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
EP1963324B1 (en) 2005-12-22 2010-04-21 Glaxo Group Limited Heterocyclic compounds, their preparation and their use as antibacterials
ES2331930T3 (es) * 2006-02-14 2010-01-20 Pfizer Products Inc. Oxazolidinonas con benzoxazinonas y benzoxazepinonas como agentes antibacterianos.
KR101409261B1 (ko) 2006-05-26 2014-06-18 다이쇼 세이야꾸 가부시끼가이샤 신규의 복소환 화합물 또는 그 염 및 그 중간체
EP2032551B9 (en) 2006-06-16 2012-02-29 Pharma Mar, S.A. Antitumoral dihydropyran-2-one compounds
EP2086540B8 (en) 2006-12-01 2011-03-02 Galapagos N.V. Triazolopyridine compounds useful for the treatment of degenerative & inflammatory diseases
CL2008001003A1 (es) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
CL2008001002A1 (es) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.

Also Published As

Publication number Publication date
CN102015698A (zh) 2011-04-13
RU2501799C2 (ru) 2013-12-20
EP2254887B1 (en) 2012-12-19
EP2254887B9 (en) 2013-05-29
RU2010138840A (ru) 2012-03-27
EP2254887A1 (en) 2010-12-01
CA2713187C (en) 2016-06-07
WO2009104159A1 (en) 2009-08-27
MX2010008921A (es) 2010-09-07
US20100331308A1 (en) 2010-12-30
ES2398939T3 (es) 2013-03-22
TW200940534A (en) 2009-10-01
JP5404652B2 (ja) 2014-02-05
JP2011512401A (ja) 2011-04-21
AR070458A1 (es) 2010-04-07
KR101592046B1 (ko) 2016-02-05
BRPI0908208A2 (pt) 2015-08-25
CN102015698B (zh) 2014-08-27
ES2398939T9 (es) 2013-07-24
AU2009215247A1 (en) 2009-08-27
KR20100124282A (ko) 2010-11-26
US8349826B2 (en) 2013-01-08
CA2713187A1 (en) 2009-08-27
TWI429643B (zh) 2014-03-11

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