PL2115140T3 - Dodatnio naładowane rozpuszczalne w wodzie proleki 1H-imidazo[4,5-c]chinolino-4-amin i powiązane związki o bardzo wysokich wskaźnikach penetracji przez skórę - Google Patents

Dodatnio naładowane rozpuszczalne w wodzie proleki 1H-imidazo[4,5-c]chinolino-4-amin i powiązane związki o bardzo wysokich wskaźnikach penetracji przez skórę

Info

Publication number: PL2115140T3
Authority: PL; Poland
Prior art keywords: quinolin; imidazo; amines; positively charged; related compounds
Prior art date: 2007-01-31

Application number

PL07705747T

Other languages

English (en)

Inventor

Chongxi Yu

Original Assignee

Yu

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-01-31

Filing date

2007-01-31

Publication date

2017-03-31

2007-01-31 Application filed by Yu filed Critical Yu

2017-03-31 Publication of PL2115140T3 publication Critical patent/PL2115140T3/pl

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Virology (AREA)
Bioinformatics & Cheminformatics (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Epidemiology (AREA)
Dermatology (AREA)
Molecular Biology (AREA)
Pulmonology (AREA)
Hematology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biotechnology (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Gastroenterology & Hepatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)

PL07705747T 2007-01-31 2007-01-31 Dodatnio naładowane rozpuszczalne w wodzie proleki 1H-imidazo[4,5-c]chinolino-4-amin i powiązane związki o bardzo wysokich wskaźnikach penetracji przez skórę PL2115140T3 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
PCT/IB2007/050322 WO2008093173A1 (en)	2007-01-31	2007-01-31	Positively charged water-soluble prodrugs of 1h-imidazo[4, 5-c]quinolin-4-amines and related compounds with very high skin penetration rates
EP07705747.9A EP2115140B8 (en)	2007-01-31	2007-01-31	Positively charged water-soluble prodrugs of 1H-imidazo[4,5-c]quinolin-4-amines and related compounds with very high skin penetration rates

Publications (1)

Publication Number	Publication Date
PL2115140T3 true PL2115140T3 (pl)	2017-03-31

Family

ID=39673699

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL07705747T PL2115140T3 (pl)	2007-01-31	2007-01-31	Dodatnio naładowane rozpuszczalne w wodzie proleki 1H-imidazo[4,5-c]chinolino-4-amin i powiązane związki o bardzo wysokich wskaźnikach penetracji przez skórę

Country Status (10)

Country	Link
US (2)	US8349866B2 (pl)
EP (2)	EP3176169A1 (pl)
JP (1)	JP5389668B2 (pl)
CN (1)	CN101595217B (pl)
AU (3)	AU2007345952C1 (pl)
CA (1)	CA2675845C (pl)
ES (1)	ES2607901T3 (pl)
HU (1)	HUE031307T2 (pl)
PL (1)	PL2115140T3 (pl)
WO (1)	WO2008093173A1 (pl)

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EP2656879B1 (en)	2006-12-10	2017-06-28	Chongxi Yu	Transdermal delivery systems of beta-lactam antibiotics
EP3181132A1 (en)	2007-01-15	2017-06-21	Chongxi Yu	Positively charged water-soluble prodrugs of retinoids and retinoid-like compounds with very high skin penetration rates
PL2115140T3 (pl)	2007-01-31	2017-03-31	Yu	Dodatnio naładowane rozpuszczalne w wodzie proleki 1H-imidazo[4,5-c]chinolino-4-amin i powiązane związki o bardzo wysokich wskaźnikach penetracji przez skórę
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CN101541743A (zh)	2006-11-08	2009-09-23	于崇曦	多肽及相关化合物的透皮给药***
EP2656879B1 (en)	2006-12-10	2017-06-28	Chongxi Yu	Transdermal delivery systems of beta-lactam antibiotics
PL2115140T3 (pl)	2007-01-31	2017-03-31	Yu	Dodatnio naładowane rozpuszczalne w wodzie proleki 1H-imidazo[4,5-c]chinolino-4-amin i powiązane związki o bardzo wysokich wskaźnikach penetracji przez skórę
CA2691446C (en)	2007-06-04	2021-07-06	Techfields Inc	Pro-drugs of nsaias with very high skin and membranes penetration rates and their new medicinal uses
EA025993B1 (ru) *	2009-07-13	2017-02-28	Медисис Фармасьютикал Корпорейшн	Композиции с более низким содержанием имиквимода и короткие режимы дозирования для лечения остроконечных и перианальных бородавок

2007
- 2007-01-31 PL PL07705747T patent/PL2115140T3/pl unknown
- 2007-01-31 JP JP2009547772A patent/JP5389668B2/ja not_active Expired - Fee Related
- 2007-01-31 HU HUE07705747A patent/HUE031307T2/hu unknown
- 2007-01-31 AU AU2007345952A patent/AU2007345952C1/en not_active Ceased
- 2007-01-31 ES ES07705747.9T patent/ES2607901T3/es active Active
- 2007-01-31 CN CN200780050660.9A patent/CN101595217B/zh active Active
- 2007-01-31 EP EP16200797.5A patent/EP3176169A1/en active Pending
- 2007-01-31 WO PCT/IB2007/050322 patent/WO2008093173A1/en active Application Filing
- 2007-01-31 CA CA2675845A patent/CA2675845C/en active Active
- 2007-01-31 EP EP07705747.9A patent/EP2115140B8/en active Active
2009
- 2009-07-31 US US12/534,096 patent/US8349866B2/en active Active
2012
- 2012-12-31 US US13/732,256 patent/US9567329B2/en active Active
2014
- 2014-09-12 AU AU2014224111A patent/AU2014224111B2/en not_active Ceased
2017
- 2017-03-14 AU AU2017201728A patent/AU2017201728A1/en not_active Abandoned

Also Published As

Publication number	Publication date
AU2014224111A1 (en)	2014-10-02
JP2010516802A (ja)	2010-05-20
EP2115140B8 (en)	2017-01-25
HUE031307T2 (hu)	2017-07-28
AU2017201728A1 (en)	2017-03-30
EP2115140A1 (en)	2009-11-11
US20130131100A1 (en)	2013-05-23
AU2014224111B2 (en)	2016-12-15
EP2115140A4 (en)	2011-01-05
US20100021394A1 (en)	2010-01-28
WO2008093173A1 (en)	2008-08-07
CN101595217A (zh)	2009-12-02
CA2675845C (en)	2019-03-05
EP2115140B1 (en)	2016-11-30
US9567329B2 (en)	2017-02-14
US8349866B2 (en)	2013-01-08
JP5389668B2 (ja)	2014-01-15
CN101595217B (zh)	2016-06-08
AU2007345952B2 (en)	2014-06-12
AU2007345952A1 (en)	2008-08-07
ES2607901T3 (es)	2017-04-04
AU2007345952C1 (en)	2017-06-08
EP3176169A1 (en)	2017-06-07
CA2675845A1 (en)	2008-08-07

Publication	Publication Date	Title
PL2115140T3 (pl)	2017-03-31	Dodatnio naładowane rozpuszczalne w wodzie proleki 1H-imidazo[4,5-c]chinolino-4-amin i powiązane związki o bardzo wysokich wskaźnikach penetracji przez skórę
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