PL1960428T3 - Przeciwciała przeciwko amyloidowi beta z glikozylacją w regionie zmiennym - Google Patents
Przeciwciała przeciwko amyloidowi beta z glikozylacją w regionie zmiennymInfo
- Publication number
- PL1960428T3 PL1960428T3 PL06829502T PL06829502T PL1960428T3 PL 1960428 T3 PL1960428 T3 PL 1960428T3 PL 06829502 T PL06829502 T PL 06829502T PL 06829502 T PL06829502 T PL 06829502T PL 1960428 T3 PL1960428 T3 PL 1960428T3
- Authority
- PL
- Poland
- Prior art keywords
- glycosylation
- variable region
- antibodies against
- amyloid beta
- against amyloid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05027090 | 2005-12-12 | ||
EP06829502A EP1960428B1 (en) | 2005-12-12 | 2006-12-11 | Antibodies against amyloid beta with glycosylation in the variable region |
PCT/EP2006/011914 WO2007068429A1 (en) | 2005-12-12 | 2006-12-11 | Antibodies against amyloid beta 4 with glycosylated in the variable region |
Publications (1)
Publication Number | Publication Date |
---|---|
PL1960428T3 true PL1960428T3 (pl) | 2012-02-29 |
Family
ID=37745986
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL06829502T PL1960428T3 (pl) | 2005-12-12 | 2006-12-11 | Przeciwciała przeciwko amyloidowi beta z glikozylacją w regionie zmiennym |
Country Status (34)
Country | Link |
---|---|
US (2) | US8906370B2 (pl) |
EP (2) | EP2377886A1 (pl) |
JP (1) | JP5145241B2 (pl) |
KR (2) | KR20080077132A (pl) |
CN (2) | CN102659943B (pl) |
AR (1) | AR057233A1 (pl) |
AT (1) | ATE517923T1 (pl) |
AU (1) | AU2006326301B2 (pl) |
BR (1) | BRPI0619605B8 (pl) |
CA (1) | CA2632828C (pl) |
CR (1) | CR10000A (pl) |
CY (1) | CY1114783T1 (pl) |
DK (1) | DK1960428T3 (pl) |
DO (1) | DOP2006000278A (pl) |
EC (1) | ECSP088524A (pl) |
ES (1) | ES2368591T3 (pl) |
HK (2) | HK1130066A1 (pl) |
IL (1) | IL191004A (pl) |
JO (1) | JO2824B1 (pl) |
MA (1) | MA30038B1 (pl) |
MY (1) | MY155286A (pl) |
NO (1) | NO346105B1 (pl) |
NZ (1) | NZ568241A (pl) |
PE (3) | PE20100684A1 (pl) |
PL (1) | PL1960428T3 (pl) |
PT (1) | PT1960428E (pl) |
RS (1) | RS52004B (pl) |
RU (1) | RU2438706C2 (pl) |
SI (1) | SI1960428T1 (pl) |
TW (1) | TWI382990B (pl) |
UA (1) | UA99097C2 (pl) |
UY (1) | UY30003A1 (pl) |
WO (1) | WO2007068429A1 (pl) |
ZA (1) | ZA200805038B (pl) |
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DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
BRPI0619249A2 (pt) | 2005-11-30 | 2011-09-20 | Abbott Lab | anticorpos anti-globulÈmeros-aß, frações que se ligam a antìgeno destes, hibridomas correspondentes, ácidos nucléicos, vetores, células hospedeiras, métodos de produzir os ditos anticorpos, composições compreendendo os ditos anticorpos, usos dos ditos anticorpos e métodos de usar os ditos anticorpos |
CN101506236B (zh) | 2005-11-30 | 2012-12-12 | 雅培制药有限公司 | 抗淀粉样β蛋白的单克隆抗体及其用途 |
PE20100684A1 (es) * | 2005-12-12 | 2010-10-04 | Hoffmann La Roche | Anticuerpo anti b-4-amiloide que contiene asparagina glicosilada en la region variable de vh |
US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
CA2671968A1 (en) * | 2006-12-11 | 2008-06-19 | F. Hoffmann-La Roche Ag | Abeta antibody parenteral formulation |
EP2486928A1 (en) | 2007-02-27 | 2012-08-15 | Abbott GmbH & Co. KG | Method for the treatment of amyloidoses |
US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
US8048420B2 (en) | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
EP3351557A1 (en) | 2007-06-29 | 2018-07-25 | F. Hoffmann-La Roche AG | Heavy chain mutant leading to improved immunoglobulin production |
EP2527367A1 (en) | 2007-08-20 | 2012-11-28 | Glaxo Group Limited | Production method |
CN101883790B (zh) | 2007-10-05 | 2015-09-09 | 基因技术公司 | 抗淀粉样蛋白β抗体在眼病中的用途 |
MX2010006395A (es) * | 2007-12-21 | 2010-07-01 | Hoffmann La Roche | Formulacion de anticuerpos. |
EP2282773B1 (en) * | 2008-05-02 | 2014-01-15 | Seattle Genetics, Inc. | Methods and compositions for making antibodies and antibody derivatives with reduced core fucosylation |
US20120282654A1 (en) * | 2009-04-29 | 2012-11-08 | Schering Corporation | Antibody purification |
US20130116413A1 (en) * | 2009-12-29 | 2013-05-09 | Dr. Reddy's Laboratories, Inc. | Purification of proteins |
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MX360403B (es) | 2010-04-15 | 2018-10-31 | Abbvie Inc | Proteinas de union a amiloide beta. |
RU2607368C2 (ru) | 2010-07-30 | 2017-01-10 | Ац Иммуне С.А. | Безопасные и функциональные гуманизированные антитела |
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RS58928B1 (sr) * | 2012-08-29 | 2019-08-30 | Hoffmann La Roche | Transporter za krvno-moždanu barijeru |
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-
2006
- 2006-12-11 PE PE2010000354A patent/PE20100684A1/es not_active Application Discontinuation
- 2006-12-11 PT PT06829502T patent/PT1960428E/pt unknown
- 2006-12-11 AT AT06829502T patent/ATE517923T1/de active
- 2006-12-11 US US12/086,309 patent/US8906370B2/en active Active
- 2006-12-11 PE PE2010000560A patent/PE20100748A1/es active IP Right Grant
- 2006-12-11 CA CA2632828A patent/CA2632828C/en active Active
- 2006-12-11 ES ES06829502T patent/ES2368591T3/es active Active
- 2006-12-11 JP JP2008543748A patent/JP5145241B2/ja active Active
- 2006-12-11 EP EP11169488A patent/EP2377886A1/en not_active Withdrawn
- 2006-12-11 UA UAA200808791A patent/UA99097C2/ru unknown
- 2006-12-11 AU AU2006326301A patent/AU2006326301B2/en active Active
- 2006-12-11 CN CN201210137369.8A patent/CN102659943B/zh active Active
- 2006-12-11 RS RS20110401A patent/RS52004B/en unknown
- 2006-12-11 JO JO2006444A patent/JO2824B1/en active
- 2006-12-11 KR KR1020087012289A patent/KR20080077132A/ko active Search and Examination
- 2006-12-11 PE PE2006001587A patent/PE20071002A1/es not_active Application Discontinuation
- 2006-12-11 SI SI200631096T patent/SI1960428T1/sl unknown
- 2006-12-11 MY MYPI20081349A patent/MY155286A/en unknown
- 2006-12-11 KR KR1020127010552A patent/KR101401159B1/ko active IP Right Grant
- 2006-12-11 RU RU2008128138/10A patent/RU2438706C2/ru active
- 2006-12-11 CN CN2006800463079A patent/CN101351476B/zh active Active
- 2006-12-11 TW TW095146304A patent/TWI382990B/zh active
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