PL1761520T3 - Inhibitory kinazy - Google Patents
Inhibitory kinazyInfo
- Publication number
- PL1761520T3 PL1761520T3 PL05766569T PL05766569T PL1761520T3 PL 1761520 T3 PL1761520 T3 PL 1761520T3 PL 05766569 T PL05766569 T PL 05766569T PL 05766569 T PL05766569 T PL 05766569T PL 1761520 T3 PL1761520 T3 PL 1761520T3
- Authority
- PL
- Poland
- Prior art keywords
- kinase inhibitors
- formula
- present
- inhibitors
- provides kinase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04380131A EP1609789A1 (en) | 2004-06-23 | 2004-06-23 | Ureido-pyrazole derivatives and their use as kinase inhibitors |
| US59253904P | 2004-07-30 | 2004-07-30 | |
| EP04380174 | 2004-08-23 | ||
| US62249204P | 2004-10-27 | 2004-10-27 | |
| PCT/US2005/021148 WO2006009741A1 (en) | 2004-06-23 | 2005-06-15 | Kinase inhibitors |
| EP05766569A EP1761520B1 (en) | 2004-06-23 | 2005-06-15 | Kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1761520T3 true PL1761520T3 (pl) | 2008-12-31 |
Family
ID=43875180
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05766569T PL1761520T3 (pl) | 2004-06-23 | 2005-06-15 | Inhibitory kinazy |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7767674B2 (pl) |
| EP (1) | EP1761520B1 (pl) |
| AT (1) | ATE400567T1 (pl) |
| DK (1) | DK1761520T3 (pl) |
| ES (1) | ES2308523T3 (pl) |
| PL (1) | PL1761520T3 (pl) |
| PT (1) | PT1761520E (pl) |
| SI (1) | SI1761520T1 (pl) |
| WO (1) | WO2006009741A1 (pl) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1608319A4 (en) | 2003-04-03 | 2007-02-28 | Univ California | IMPROVED HEMMER FOR SOLUBLE EPOXY HYDROLASE |
| WO2005089380A2 (en) | 2004-03-16 | 2005-09-29 | The Regents Of The University Of California | Reducing nephropathy with inhibitors of soluble epoxide hydrolase and epoxyeicosanoids |
| WO2006045119A2 (en) | 2004-10-20 | 2006-04-27 | The Regents Of The University Of California | Improved inhibitors for the soluble epoxide hydrolase |
| PE20070640A1 (es) * | 2005-10-28 | 2007-08-10 | Lilly Co Eli | Compuestos derivados de pirazol-isoquinolina urea como inhibidores de la cinasa p38 |
| DOP2006000234A (es) * | 2005-10-28 | 2007-05-31 | Lilly Co Eli | Inhibidores de cinasa |
| TW200808723A (en) * | 2006-03-13 | 2008-02-16 | Univ California | Conformationally restricted urea inhibitors of soluble epoxide hydrolase |
| EP1992344A1 (en) | 2007-05-18 | 2008-11-19 | Institut Curie | P38 alpha as a therapeutic target in pathologies linked to FGFR3 mutation |
| EP2170871A2 (en) * | 2007-06-26 | 2010-04-07 | GlaxoSmithKline LLC | Processes for preparing benzimidazole thiophenes |
| US8314091B2 (en) | 2007-08-20 | 2012-11-20 | Msd Oss B.V. | N-benzyl,N'-arylcarbonylpiperazine derivatives |
| WO2009119534A1 (ja) | 2008-03-26 | 2009-10-01 | 第一三共株式会社 | 新規テトラヒドロイソキノリン誘導体 |
| TW201022230A (en) * | 2008-08-28 | 2010-06-16 | Organon Nv | 1-(4-ureidobenzoyl)piperazine derivatives |
| CN102256964A (zh) | 2008-10-02 | 2011-11-23 | 瑞斯比维特有限公司 | p38MAP激酶抑制剂 |
| GB0818033D0 (en) | 2008-10-02 | 2008-11-05 | Respivert Ltd | Novel compound |
| CA2746357A1 (en) | 2008-12-11 | 2010-06-17 | Respivert Limited | P38 map kinase inhibitors |
| WO2010094956A1 (en) | 2009-02-17 | 2010-08-26 | Pulmagen Therapeutics (Inflammation) Limited. | Triazolopyridine derivatives as p38 map kinase inhibitors |
| GB0905955D0 (en) | 2009-04-06 | 2009-05-20 | Respivert Ltd | Novel compounds |
| EP2488511A1 (en) * | 2009-10-02 | 2012-08-22 | Vertex Pharmaceuticals Incorporated | Pyrazole inhibitors of phosphatidylinositol 3-kinase |
| US9452980B2 (en) | 2009-12-22 | 2016-09-27 | Hoffmann-La Roche Inc. | Substituted benzamides |
| EP2528604B1 (en) | 2010-01-29 | 2017-11-22 | The Regents of the University of California | Acyl piperidine inhibitors of soluble epoxide hydrolase |
| GB201009731D0 (en) | 2010-06-10 | 2010-07-21 | Pulmagen Therapeutics Inflamma | Kinase inhibitors |
| SG11201402986RA (en) | 2011-12-09 | 2014-12-30 | Chiesi Farma Spa | Kinase inhibitors |
| DK2788349T3 (en) | 2011-12-09 | 2017-01-30 | Chiesi Farm Spa | kinase inhibitors |
| US9150570B2 (en) * | 2012-05-31 | 2015-10-06 | Plexxikon Inc. | Synthesis of heterocyclic compounds |
| CN105377847A (zh) | 2013-06-06 | 2016-03-02 | 奇斯药制品公司 | 激酶抑制剂 |
| TW201730189A (zh) | 2015-12-23 | 2017-09-01 | 吉斯藥品公司 | 激酶抑制劑 |
| EP3394058B1 (en) | 2015-12-23 | 2020-10-14 | Chiesi Farmaceutici S.p.A. | N-[3-(3-{4-[[1,2,4]triazolo[4,3-a]pyridin-6-yloxy]-1,2,3,4-tetrahydro-naphthalen-1-yl} -ureido)-phenyl]-methanesulfonamide derivatives and their use as p38 mapk inhibitors |
| ES2819830T3 (es) | 2016-03-17 | 2021-04-19 | Hoffmann La Roche | Derivado de 5-etiol-4-metil-pirazol-3-carboxamida que tiene actividad como agonista de TAAR |
| CN107619388A (zh) | 2016-07-13 | 2018-01-23 | 南京天印健华医药科技有限公司 | 作为fgfr抑制剂的杂环化合物 |
| CN107840842A (zh) | 2016-09-19 | 2018-03-27 | 北京天诚医药科技有限公司 | 炔代杂环化合物、其制备方法及其在医药学上的应用 |
| CA3128468A1 (en) | 2017-10-05 | 2019-04-11 | Fulcrum Therapeutics, Inc. | P38 kinase inhibitors reduce dux4 and downstream gene expression for the treatment of fshd |
| US10342786B2 (en) | 2017-10-05 | 2019-07-09 | Fulcrum Therapeutics, Inc. | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA73492C2 (en) | 1999-01-19 | 2005-08-15 | Aromatic heterocyclic compounds as antiinflammatory agents | |
| ID30176A (id) * | 1999-03-12 | 2001-11-08 | Boehringer Ingelheim Pharma | Senyawa-senyawa yang bermanfaat sebagai zat anti-inflamasi |
| JP4629978B2 (ja) * | 2002-02-25 | 2011-02-09 | ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド | サイトカイン媒介疾患の治療に有用な１，４−二置換ベンゾ縮合シクロアルキル尿素化合物 |
| GB0320244D0 (en) * | 2003-05-06 | 2003-10-01 | Aventis Pharma Inc | Pyrazoles as inhibitors of tumour necrosis factor |
| US20070010529A1 (en) * | 2003-05-19 | 2007-01-11 | Kanji Takahashi | Nitrogenous heterocyclic compounds and medical use thereof |
-
2005
- 2005-06-15 ES ES05766569T patent/ES2308523T3/es active Active
- 2005-06-15 US US11/569,809 patent/US7767674B2/en not_active Expired - Fee Related
- 2005-06-15 DK DK05766569T patent/DK1761520T3/da active
- 2005-06-15 AT AT05766569T patent/ATE400567T1/de not_active IP Right Cessation
- 2005-06-15 PL PL05766569T patent/PL1761520T3/pl unknown
- 2005-06-15 WO PCT/US2005/021148 patent/WO2006009741A1/en not_active Application Discontinuation
- 2005-06-15 EP EP05766569A patent/EP1761520B1/en active Active
- 2005-06-15 SI SI200530351T patent/SI1761520T1/sl unknown
- 2005-06-15 PT PT05766569T patent/PT1761520E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2308523T3 (es) | 2008-12-01 |
| ATE400567T1 (de) | 2008-07-15 |
| DK1761520T3 (da) | 2008-10-27 |
| WO2006009741A1 (en) | 2006-01-26 |
| PT1761520E (pt) | 2008-09-15 |
| SI1761520T1 (sl) | 2008-10-31 |
| US20080306068A1 (en) | 2008-12-11 |
| US7767674B2 (en) | 2010-08-03 |
| EP1761520B1 (en) | 2008-07-09 |
| EP1761520A1 (en) | 2007-03-14 |
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