PH12020550635A1 - Production method of intermediate compound for synthesizing medicament - Google Patents

Production method of intermediate compound for synthesizing medicament

Info

Publication number
PH12020550635A1
PH12020550635A1 PH12020550635A PH12020550635A PH12020550635A1 PH 12020550635 A1 PH12020550635 A1 PH 12020550635A1 PH 12020550635 A PH12020550635 A PH 12020550635A PH 12020550635 A PH12020550635 A PH 12020550635A PH 12020550635 A1 PH12020550635 A1 PH 12020550635A1
Authority
PH
Philippines
Prior art keywords
production method
intermediate compound
synthesizing
medicament
synthesizing medicament
Prior art date
Application number
PH12020550635A
Other languages
English (en)
Inventor
Jongwon Park
Seok Ju Lee
In Ae Ryu
Bongchan Kim
Original Assignee
Lg Chemical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/KR2018/012575 external-priority patent/WO2019098551A1/ko
Application filed by Lg Chemical Ltd filed Critical Lg Chemical Ltd
Publication of PH12020550635A1 publication Critical patent/PH12020550635A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/02Monohydroxylic acyclic alcohols
    • C07C31/04Methanol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/45Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/12Saturated polycyclic compounds
    • C07C61/125Saturated polycyclic compounds having a carboxyl group bound to a condensed ring system
    • C07C61/13Saturated polycyclic compounds having a carboxyl group bound to a condensed ring system having two rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/10Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with ester groups or with a carbon-halogen bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PH12020550635A 2017-11-16 2020-05-15 Production method of intermediate compound for synthesizing medicament PH12020550635A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20170153334 2017-11-16
PCT/KR2018/012575 WO2019098551A1 (ko) 2017-11-16 2018-10-23 의약품 합성용 중간체 화합물의 제조 방법
KR1020180126663A KR102184129B1 (ko) 2017-11-16 2018-10-23 의약품 합성용 중간체 화합물의 제조 방법

Publications (1)

Publication Number Publication Date
PH12020550635A1 true PH12020550635A1 (en) 2021-02-22

Family

ID=66680122

Family Applications (1)

Application Number Title Priority Date Filing Date
PH12020550635A PH12020550635A1 (en) 2017-11-16 2020-05-15 Production method of intermediate compound for synthesizing medicament

Country Status (8)

Country Link
KR (1) KR102184129B1 (ko)
CN (1) CN111247127B (ko)
BR (1) BR112020009568A2 (ko)
CL (1) CL2020001285A1 (ko)
CO (1) CO2020006788A2 (ko)
PE (1) PE20210839A1 (ko)
PH (1) PH12020550635A1 (ko)
RU (1) RU2741389C1 (ko)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2721185A1 (de) * 1977-05-11 1978-11-16 Bayer Ag Verfahren zur herstellung von substituierten vinylcyclopropancarbonsaeurebenzylestern
JPH04316526A (ja) * 1991-04-15 1992-11-06 Asahi Chem Ind Co Ltd カルボン酸エステルのアルカリ加水分解法
TW460452B (en) * 1998-09-14 2001-10-21 Rhodia Fiber & Amp Resin Inter Process for the crystallization of carboxylic acid and process for manufacturing crystalline carboxylic acid
TWI357902B (en) * 2005-04-01 2012-02-11 Lg Life Science Ltd Dipeptidyl peptidase-iv inhibiting compounds, meth
JP2008201719A (ja) * 2007-02-20 2008-09-04 Nippon Oil Corp テトラカルボン酸およびその酸二無水物の製造方法
BRPI0819719B8 (pt) * 2007-12-21 2021-05-25 Lg Chemical Ltd compostos de inibição de dipeptidil peptidase-iv, métodos de preparação dos mesmos, e preparações farmacêuticas contendo os mesmos como agente ativo
US8741927B2 (en) * 2010-09-03 2014-06-03 Lg Life Sciences Ltd. Production method of intermediate compound for synthesizing medicament

Also Published As

Publication number Publication date
RU2741389C1 (ru) 2021-01-25
KR102184129B1 (ko) 2020-11-27
CN111247127A (zh) 2020-06-05
CL2020001285A1 (es) 2020-10-23
BR112020009568A2 (pt) 2021-03-09
KR20190056296A (ko) 2019-05-24
CN111247127B (zh) 2024-02-06
PE20210839A1 (es) 2021-05-06
CO2020006788A2 (es) 2020-06-09

Similar Documents

Publication Publication Date Title
MX2021003459A (es) Proceso de fabricacion de un compuesto para la inhibicion de la actividad de shp2.
MX2021003460A (es) Fabricacion de compuestos y composiciones para inhibir la actividad de shp2.
NZ600119A (en) Process and intermediates for the preparation of 5-biphenyl-4-yl-2-methylpentanoic acid derivatives
SG11201810655QA (en) Method for producing substituted polycyclic pyridone derivative and crystal of same
MX361653B (es) Procedimiento para la preparación de derivados del ácido biliar.
NZ718009A (en) Process for producing diazabicyclooctane derivative and intermediate thereof
HK1166074A1 (en) Furopyrimidinedione derivatives as trpa1 modulators
PH12015501226A1 (en) Crystalline 6,7-unsaturated-7-carbamoyl morphinane derivative, and method for producing the same
MX2021000348A (es) 2-fluoro-3-nitrotolueno cristalino y procedimiento para la preparacion del mismo.
PH12019502093A1 (en) Novel ester compounds, method for the production thereof and use thereof
IN2014MN01521A (ko)
SG10201902609TA (en) Method for producing novel nitrogen-containing compound or salt thereof, and production intermediate of same
MX2018014128A (es) 6.7.beta-epoxidos esteroideos como intermedios quimicos.
MX2017001459A (es) Sintesis de fosforamidatos.
MX2018014130A (es) Procedimiento e intermedios para la 6,7-alfa-epoxidacion de 4,6-dienos esteroideos.
MX2015011375A (es) Moduladores del receptor acoplado a proteina-g 120 (gpr120) de acido biciclo-[2.2.1].
BR112019001447A2 (pt) método de produção para composto pirazol-amida
SG10201901578UA (en) Processes for the preparation of pyrimidinylcyclopentane compounds
PH12020550635A1 (en) Production method of intermediate compound for synthesizing medicament
MX2020005099A (es) Metodo de produccion de un compuesto intermedio para sintetizar un medicamento.
CA2928305C (en) A crystalline anhydrous form of cabazitaxel, process for the preparation and pharmaceutical compositions thereof
NZ711329A (en) A process for preparation of (2s, 5r)- sulfuric acid mono-{ [(4-aminopiperidin-4-yl) carbonyl]-7-oxo-1,6-diaza-bicyclo[3.2.1]-oct-6-yl} ester
MX2021006499A (es) Proceso de preparacion de un enol eter biciclico.
MX2021001530A (es) Metodo de produccion de esteres carbonicos.
MX2021006692A (es) Proceso mejorado para preparar ozanimod.