PE20171243A1 - Composicion de liberacion modificada de orlistat y acarbosa para el tratamiento de la obesidad y trastornos metabolicos relacionados - Google Patents

Composicion de liberacion modificada de orlistat y acarbosa para el tratamiento de la obesidad y trastornos metabolicos relacionados

Info

Publication number
PE20171243A1
PE20171243A1 PE2017000981A PE2017000981A PE20171243A1 PE 20171243 A1 PE20171243 A1 PE 20171243A1 PE 2017000981 A PE2017000981 A PE 2017000981A PE 2017000981 A PE2017000981 A PE 2017000981A PE 20171243 A1 PE20171243 A1 PE 20171243A1
Authority
PE
Peru
Prior art keywords
orlistat
obesity
treatment
modified release
acarbosa
Prior art date
Application number
PE2017000981A
Other languages
English (en)
Inventor
Goran Alderbron
Anders Forslund
Ulf Holmback
Hans Lennernas
Jan Stefan Persson Gruden
Original Assignee
Empros Pharma Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52146175&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20171243(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Empros Pharma Ab filed Critical Empros Pharma Ab
Publication of PE20171243A1 publication Critical patent/PE20171243A1/es

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    • A—HUMAN NECESSITIES
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    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
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    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
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    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)

Abstract

Se refiere a una composicion de liberacion modificada que comprende orlistat y acarbosa, que comprende partes individualmente distintas con diferentes patrones de liberacion: a) una primera parte, G1, que comprende aproximadamente (5 a 70)% p/p de la dosis total de acarbosa, b) una segunda parte, G2A, que comprende aproximadamente (30 a 95)% p/p de la dosis total de acarbosa, c) una tercera parte, G2B, que comprende aproximadamente (10 a 90)% p/p de la dosis total de orlistat, y d) una cuarta parte, G3, que comprende aproximadamente 10% p/p a aproximadamente 80% p/p de la dosis total de orlistat; y la concentracion total de acarbosa y orlistat, respectivamente, en la composicion de 100% p/p. Dicha composicion es util en el tratamiento de enfermedades metabolicas tales como obesidad, sobrepeso y diabetes tipo 2
PE2017000981A 2014-12-17 2015-12-17 Composicion de liberacion modificada de orlistat y acarbosa para el tratamiento de la obesidad y trastornos metabolicos relacionados PE20171243A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14198468 2014-12-17

Publications (1)

Publication Number Publication Date
PE20171243A1 true PE20171243A1 (es) 2017-08-24

Family

ID=52146175

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2017000981A PE20171243A1 (es) 2014-12-17 2015-12-17 Composicion de liberacion modificada de orlistat y acarbosa para el tratamiento de la obesidad y trastornos metabolicos relacionados

Country Status (28)

Country Link
US (2) US10561617B2 (es)
EP (3) EP3943076A3 (es)
JP (1) JP6607955B2 (es)
KR (2) KR101937069B1 (es)
CN (1) CN107405309B (es)
AU (1) AU2015367422B2 (es)
BR (1) BR112017012714B1 (es)
CA (1) CA2970991C (es)
CL (1) CL2017001574A1 (es)
CO (1) CO2017005834A2 (es)
DK (1) DK3233066T3 (es)
EA (1) EA033448B1 (es)
EC (1) ECSP17035750A (es)
ES (1) ES2901122T3 (es)
HU (1) HUE057093T2 (es)
IL (1) IL252865B2 (es)
MX (3) MX2017007493A (es)
MY (1) MY195038A (es)
NZ (1) NZ732241A (es)
PE (1) PE20171243A1 (es)
PH (1) PH12017550023A1 (es)
PL (1) PL3233066T3 (es)
SA (1) SA517381713B1 (es)
SG (1) SG11201704470PA (es)
SI (1) SI3233066T1 (es)
UA (1) UA122403C2 (es)
WO (1) WO2016097170A1 (es)
ZA (1) ZA201704590B (es)

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SI3233066T1 (sl) 2014-12-17 2022-02-28 Empros Pharma AB, c/o BTR, Sestavek s prirejenim sproščanjem, ki vsebuje orlistat in akarbozo za zdravljenje prekomerne teže in povezanih metaboličnih motenj
WO2017213208A1 (ja) * 2016-06-09 2017-12-14 Ｄｓファーマアニマルヘルス株式会社 動物用徐放性製剤組成物
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BR112022011055A2 (pt) 2019-12-11 2022-08-23 Evonik Operations Gmbh Forma de dosagem para uso no tratamento ou na prevenção de uma doença
CN111297826B (zh) * 2020-04-20 2021-08-03 鲁南制药集团股份有限公司 一种稳定的奥利司他胶囊及其制备方法
WO2022154687A1 (ru) * 2021-01-14 2022-07-21 Общество C Ограниченной Ответственностью "Новамедика" Фармацевтическая композиция, включающая эзомепразол
CA3219508A1 (en) 2021-05-21 2022-11-24 Jan Stefan Persson Gruden Reduced rebound effects in subjects treated for overweight or obesity
WO2022243528A1 (en) 2021-05-21 2022-11-24 Empros Pharma Ab Use of a composition comprising orlistat and acarbose to obtain a sustained weight loss
WO2022243525A1 (en) 2021-05-21 2022-11-24 Empros Pharma Ab Synergistic effects on weight loss, improved quality of life and gastro-intestinal side effects with a composition of orlistat and acarbose

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