PE20121685A1 - Antigeno ndv recombinante y usos del mismo - Google Patents
Antigeno ndv recombinante y usos del mismoInfo
- Publication number
- PE20121685A1 PE20121685A1 PE2012000888A PE2012000888A PE20121685A1 PE 20121685 A1 PE20121685 A1 PE 20121685A1 PE 2012000888 A PE2012000888 A PE 2012000888A PE 2012000888 A PE2012000888 A PE 2012000888A PE 20121685 A1 PE20121685 A1 PE 20121685A1
- Authority
- PE
- Peru
- Prior art keywords
- ndv
- antigen
- same
- polypeptide
- variety
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 3
- 102000036639 antigens Human genes 0.000 title abstract 3
- 108091007433 antigens Proteins 0.000 title abstract 3
- 241000711404 Avian avulavirus 1 Species 0.000 abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 230000009851 immunogenic response Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
- A61K39/17—Newcastle disease virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
- C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/517—Plant cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
- C12N2760/18122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
- C12N2760/18134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Mycology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Pulmonology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
SE REFIERE A UNA COMPOSICION QUE COMPRENDE UN POLIPEPTIDO O ANTIGENO HN (HEMAGLUTININA-NEURAMINIDASA) DEL NDV (VIRUS DE LA ENFERMEDAD DE NEWCASTLE) Y UN TRANSPORTADOR, EXCIPIENTE, VEHICULO O ADYUVANTE FARMACEUTICAMENTE ACEPTABLE O APTO PARA USO VETERINARIO TAL COMO UNA EMULSION DE AGUA EN ACEITE O DE ACEITE EN AGUA. DICHO POLIPEPTIDO O ANTIGENO HN NDV TIENE AL MENOS UN 80% DE IDENTIDAD DE SECUENCIA CON LA SECUENCIA SEQ ID Nº: 3, 5, 7, 9, 15, 17 O 20, ADEMAS COMPRENDE UN FRAGMENTO INMUNOGENICO QUE COMPRENDE UNA REGION DEL EPITOPE LINEAL HN NDV. REFERIDO ADEMAS A UN METODO DE PRODUCCION. DICHA COMPOSICION GENERA UNA RESPUESTA INMUNOGENICA EN UN ANIMAL
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29029709P | 2009-12-28 | 2009-12-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20121685A1 true PE20121685A1 (es) | 2012-12-28 |
Family
ID=44189168
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2012000888A PE20121685A1 (es) | 2009-12-28 | 2010-12-28 | Antigeno ndv recombinante y usos del mismo |
Country Status (11)
Country | Link |
---|---|
US (1) | US10633667B2 (es) |
EP (2) | EP3213766A1 (es) |
JP (1) | JP5933451B2 (es) |
KR (1) | KR20120101572A (es) |
CN (1) | CN103260643A (es) |
AR (2) | AR079767A1 (es) |
CA (1) | CA2785653C (es) |
DO (1) | DOP2012000187A (es) |
MX (1) | MX351643B (es) |
PE (1) | PE20121685A1 (es) |
WO (1) | WO2011090708A2 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2519635B1 (en) * | 2009-12-28 | 2018-11-21 | Sanofi Vaccine Technologies, S.A.S. | Production of heterologous polypeptides in microalgae, microalgal extracellular bodies, compositions, and methods of making and uses thereof |
EP2519636B8 (en) * | 2009-12-28 | 2017-08-09 | DSM IP Assets B.V. | Production of hemagglutinin-neuraminidase protein in microalgae |
US10201602B2 (en) * | 2011-05-07 | 2019-02-12 | Laboratorio Avi-Mex, S.A. De C.V. | Recombinant vaccine against PRRS in a viral vector |
US9358283B2 (en) | 2011-10-28 | 2016-06-07 | The Regents Of The University Of California | Diatom-based vaccines |
EP2844760A1 (en) * | 2012-05-02 | 2015-03-11 | Algenics | Production of secreted therapeutic antibodies in microalgae |
EP2660323A1 (en) * | 2012-05-02 | 2013-11-06 | Algenics | Production of secreted therapeutic antibodies in phaeodactylum tricornutum microalgae |
EP2660324A1 (en) * | 2012-05-02 | 2013-11-06 | Algenics | Production of secreted therapeutic antibodies in microalgae |
EP2671950A1 (de) * | 2012-06-06 | 2013-12-11 | Philipps-Universität Marburg | Expression und Sekretion von rekombinanten, vollständig assemblierten Proteinkomplexen durch Mikroalgen |
CN104059927B (zh) * | 2014-05-09 | 2018-01-09 | 中国农业科学院生物技术研究所 | 鸡新城疫糖蛋白病毒抗原的制备方法及其产品 |
CN105567715B (zh) * | 2014-10-17 | 2021-06-29 | 丰益(上海)生物技术研发中心有限公司 | 裂殖壶菌α-微管蛋白相关序列及其应用 |
EP3215602B1 (en) * | 2014-11-05 | 2019-12-25 | The Research Institute at Nationwide Children's Hospital | Methods and materials for producing recombinant viruses in eukaryotic microalgae |
US10196616B2 (en) * | 2017-02-15 | 2019-02-05 | The United States Of America, As Represented By The Secretary Of Agriculture | Altered avian virus for in-ovo inoculation and methods of use thereof |
CN107099513B (zh) * | 2017-06-22 | 2020-07-14 | 北京邦卓生物科技有限公司 | 一种共表达ndv hn和ibdv vp2基因的hvt的构建及其应用 |
CN113652406B (zh) * | 2021-09-01 | 2023-05-02 | 青岛易邦生物工程有限公司 | 一种鸡传染性喉气管炎重组病毒株及其应用 |
Family Cites Families (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2909462A (en) | 1955-12-08 | 1959-10-20 | Bristol Myers Co | Acrylic acid polymer laxative compositions |
US5505941A (en) | 1981-12-24 | 1996-04-09 | Health Research, Inc. | Recombinant avipox virus and method to induce an immune response |
CA1247080A (en) | 1983-03-08 | 1988-12-20 | Commonwealth Serum Laboratories Commission | Antigenically active amino acid sequences |
US5380831A (en) | 1986-04-04 | 1995-01-10 | Mycogen Plant Science, Inc. | Synthetic insecticidal crystal protein gene |
US4761373A (en) | 1984-03-06 | 1988-08-02 | Molecular Genetics, Inc. | Herbicide resistance in plants |
EP0173552B1 (en) | 1984-08-24 | 1991-10-09 | The Upjohn Company | Recombinant dna compounds and the expression of polypeptides such as tpa |
US4945050A (en) | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
EP0290455A4 (en) | 1986-01-08 | 1989-01-18 | Rhone Poulenc Agrochimie | HALOARYLNITRILE DEGREASING GENE, THE USE THEREOF AND THE CELLS THAT CONTAIN IT. |
GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
US5990387A (en) | 1988-06-10 | 1999-11-23 | Pioneer Hi-Bred International, Inc. | Stable transformation of plant cells |
NZ230375A (en) | 1988-09-09 | 1991-07-26 | Lubrizol Genetics Inc | Synthetic gene encoding b. thuringiensis insecticidal protein |
CA2024811A1 (en) | 1989-02-24 | 1990-08-25 | David A. Fischhoff | Synthetic plant genes and method for preparation |
US5879918A (en) | 1989-05-12 | 1999-03-09 | Pioneer Hi-Bred International, Inc. | Pretreatment of microprojectiles prior to using in a particle gun |
US5202422A (en) | 1989-10-27 | 1993-04-13 | The Scripps Research Institute | Compositions containing plant-produced glycopolypeptide multimers, multimeric proteins and method of their use |
AU651101B2 (en) | 1990-04-18 | 1994-07-14 | Plant Genetic Systems N.V. | Modified bacillus thuringiensis insecticidal-crystal protein genes and their expression in plant cells |
US5932782A (en) | 1990-11-14 | 1999-08-03 | Pioneer Hi-Bred International, Inc. | Plant transformation method using agrobacterium species adhered to microprojectiles |
US6309647B1 (en) | 1999-07-15 | 2001-10-30 | Aventis Pasteur | Poxvirus—canine dispemper virus (CDV) or measles virus recombinants and compositions and methods employing the recombinants |
US5863542A (en) | 1991-03-07 | 1999-01-26 | Virogenetics Corporation | Recombinant attenuated ALVAC canaryopox virus containing heterologous HIV or SIV inserts |
KR100242671B1 (ko) | 1991-03-07 | 2000-03-02 | 고돈 에릭 | 유전학적으로 처리한 백신 균주 |
TW261517B (es) | 1991-11-29 | 1995-11-01 | Mitsubishi Shozi Kk | |
EP0652965A1 (en) | 1992-07-27 | 1995-05-17 | Pioneer Hi-Bred International, Inc. | An improved method of agrobacterium-mediated transformation of cultured soybean cells |
DE69434624T2 (de) | 1993-11-19 | 2006-12-14 | Biotechnology Research And Development Corp., Peoria | Chimäre regulatorische regionen und gen - kassetten zur genexpression in pflanzen |
JPH11504631A (ja) | 1995-04-25 | 1999-04-27 | バイカル インコーポレイテッド | Dna/脂質複合体の単一バイアル製剤 |
WO1997004122A1 (en) | 1995-07-20 | 1997-02-06 | Washington State University Research Foundation | Production of secreted foreign polypeptides in plant cell culture |
US5846946A (en) | 1996-06-14 | 1998-12-08 | Pasteur Merieux Serums Et Vaccins | Compositions and methods for administering Borrelia DNA |
FR2750866B1 (fr) | 1996-06-27 | 1998-11-27 | Rhone Merieux | Vaccin vivant recombinant aviaire, utilisant comme vecteur le virus de la laryngotracheite infectieuse aviaire |
FR2751227B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique contre les pathologies canines, notamment les pathologies respiratoires et digestives |
FR2751229B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique notamment contre la pathologie respiratoire des bovins |
FR2751224B1 (fr) | 1996-07-19 | 1998-11-20 | Rhone Merieux | Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs |
FR2751226B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique contre les pathologies du cheval |
FR2751228B1 (fr) | 1996-07-19 | 1998-11-20 | Rhone Merieux | Vaccin polynucleotidique bovin pour voie intradermique |
FR2751225B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique aviaire |
JP4111403B2 (ja) | 1996-10-11 | 2008-07-02 | ザ リージェンツ オブ ザ ユニバーシティー オブ カリフォルニア | 免疫刺激ポリヌクレオチド/免疫調節分子複合体 |
US5981840A (en) | 1997-01-24 | 1999-11-09 | Pioneer Hi-Bred International, Inc. | Methods for agrobacterium-mediated transformation |
FR2758986B1 (fr) | 1997-01-31 | 1999-04-30 | Rhone Merieux | Vaccin vivant recombinant aviaire, utilisant comme vecteur le virus de la laryngotracheite infectieuse aviaire |
IL133710A0 (en) | 1997-06-30 | 2001-04-30 | Rhone Poulence Rorer S A | Improved method for transferring nucleic acid into the striped muscle and combination thereof |
US6040498A (en) | 1998-08-11 | 2000-03-21 | North Caroline State University | Genetically engineered duckweed |
US7161064B2 (en) * | 1997-08-12 | 2007-01-09 | North Carolina State University | Method for producing stably transformed duckweed using microprojectile bombardment |
FR2778858B1 (fr) | 1998-05-20 | 2000-06-16 | Oreal | Emulsion e/h/e stable et son utilisation comme composition cosmetique et/ou dermatologique |
US8003772B2 (en) | 1999-01-14 | 2011-08-23 | Martek Biosciences Corporation | Chimeric PUFA polyketide synthase systems and uses thereof |
FR2801607B1 (fr) | 1999-11-26 | 2001-12-28 | Merial Sas | Pneumovirus du canard et vaccins correspondants |
US6852705B2 (en) | 2000-01-21 | 2005-02-08 | Merial | DNA vaccines for farm animals, in particular bovines and porcines |
US6815184B2 (en) | 2000-07-31 | 2004-11-09 | Biolex, Inc. | Expression of biologically active polypeptide in duckweed |
DK1383795T3 (da) * | 2000-11-02 | 2007-05-29 | Intervet Int Bv | Rekombinant nucleoproteinmutant fra Newcastle disease-virus som markörvaccine |
TWI324181B (en) | 2001-04-16 | 2010-05-01 | Martek Biosciences Corp | Product and process for transformation of thraustochytriales microorganisms |
EP1397676B1 (en) | 2001-05-30 | 2009-12-30 | Biolex Therapeutics, Inc. | Use of duckweed in high throughput screening |
EP1551451B1 (en) * | 2002-08-27 | 2009-02-25 | Dow AgroSciences LLC | Use of escherichia coli heat labile toxin as an adjuvant in poultry |
AU2004235813B2 (en) | 2003-05-05 | 2010-07-29 | Boyce Thompson Institute For Plant Research | Vectors and cells for preparing immunoprotective compositions derived from transgenic plants |
JP2007526215A (ja) * | 2003-05-05 | 2007-09-13 | ダウ アグロサイエンス リミテッド ライアビリティー カンパニー | トランスジェニック植物細胞に由来する安定な免疫予防的および治療的組成物ならびにその産生方法 |
SI1651265T1 (sl) | 2003-07-24 | 2008-10-31 | Merial Ltd | Formulacije cepiva, ki obsegajo emulzijo olje v vodi |
WO2006013572A2 (en) * | 2004-08-05 | 2006-02-09 | Ben Gurion University Of The Negev Research And Development Authority | Red microalgae expressing exogenous polypeptides and methods of generating and utilizing same |
JP4796786B2 (ja) * | 2005-04-28 | 2011-10-19 | 富士フイルム株式会社 | ラビリンチュラ類を形質転換可能なベクター |
JP4796787B2 (ja) | 2005-04-28 | 2011-10-19 | 富士フイルム株式会社 | ラビリンチュラ類への遺伝子導入法 |
US9216212B2 (en) * | 2005-08-05 | 2015-12-22 | University Of Massachusetts | Virus-like particles as vaccines for paramyxovirus |
US7951384B2 (en) * | 2005-08-05 | 2011-05-31 | University Of Massachusetts | Virus-like particles as vaccines for paramyxovirus |
CA2615372A1 (en) | 2007-07-13 | 2009-01-13 | Marc-Andre D'aoust | Influenza virus-like particles (vlps) comprising hemagglutinin |
PT2610345E (pt) | 2007-11-27 | 2016-01-11 | Medicago Inc | Partículas semelhantes ao vírus (vlps) da gripe recombinantes produzidas em plantas transgénicas que expressam hemaglutinina |
EP2090648A1 (en) * | 2008-02-12 | 2009-08-19 | Institut Francais de Recherche pour l'Exploitation de la Mere(Ifremer) | Production of glycosylated polypeptides in microalgae |
US7794714B2 (en) * | 2008-03-14 | 2010-09-14 | The United States Of America As Represented By The Secretary Of Agriculture | Newcastle disease virus monoclonal antibodies |
KR101715415B1 (ko) * | 2008-11-28 | 2017-03-10 | 메리얼 인코포레이티드 | 재조합 조류 인플루엔자 백신 및 그의 용도 |
EP2519636B8 (en) * | 2009-12-28 | 2017-08-09 | DSM IP Assets B.V. | Production of hemagglutinin-neuraminidase protein in microalgae |
EP2519635B1 (en) * | 2009-12-28 | 2018-11-21 | Sanofi Vaccine Technologies, S.A.S. | Production of heterologous polypeptides in microalgae, microalgal extracellular bodies, compositions, and methods of making and uses thereof |
-
2010
- 2010-12-28 US US12/979,677 patent/US10633667B2/en active Active
- 2010-12-28 CA CA2785653A patent/CA2785653C/en active Active
- 2010-12-28 EP EP17153588.3A patent/EP3213766A1/en not_active Withdrawn
- 2010-12-28 AR ARP100104979A patent/AR079767A1/es not_active Application Discontinuation
- 2010-12-28 WO PCT/US2010/062209 patent/WO2011090708A2/en active Application Filing
- 2010-12-28 PE PE2012000888A patent/PE20121685A1/es not_active Application Discontinuation
- 2010-12-28 EP EP10844257.5A patent/EP2519258B1/en active Active
- 2010-12-28 KR KR1020127020029A patent/KR20120101572A/ko not_active Application Discontinuation
- 2010-12-28 JP JP2012546255A patent/JP5933451B2/ja active Active
- 2010-12-28 CN CN2010800634100A patent/CN103260643A/zh active Pending
- 2010-12-28 MX MX2012007545A patent/MX351643B/es active IP Right Grant
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2012
- 2012-06-27 DO DO2012000187A patent/DOP2012000187A/es unknown
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2020
- 2020-10-19 AR ARP200102888A patent/AR122325A2/es unknown
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MX2012007545A (es) | 2012-11-12 |
US10633667B2 (en) | 2020-04-28 |
US20110162115A1 (en) | 2011-06-30 |
WO2011090708A2 (en) | 2011-07-28 |
MX351643B (es) | 2017-10-23 |
CA2785653C (en) | 2018-05-01 |
WO2011090708A3 (en) | 2011-12-15 |
AR079767A1 (es) | 2012-02-15 |
KR20120101572A (ko) | 2012-09-13 |
CA2785653A1 (en) | 2011-07-28 |
EP2519258A2 (en) | 2012-11-07 |
DOP2012000187A (es) | 2012-12-15 |
EP2519258B1 (en) | 2017-07-26 |
JP5933451B2 (ja) | 2016-06-08 |
JP2013515747A (ja) | 2013-05-09 |
AR122325A2 (es) | 2022-08-31 |
EP3213766A1 (en) | 2017-09-06 |
CN103260643A (zh) | 2013-08-21 |
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