PE20110891A1 - Vacuna de peptido ch3 de ige - Google Patents
Vacuna de peptido ch3 de igeInfo
- Publication number
- PE20110891A1 PE20110891A1 PE2011001186A PE2011001186A PE20110891A1 PE 20110891 A1 PE20110891 A1 PE 20110891A1 PE 2011001186 A PE2011001186 A PE 2011001186A PE 2011001186 A PE2011001186 A PE 2011001186A PE 20110891 A1 PE20110891 A1 PE 20110891A1
- Authority
- PE
- Peru
- Prior art keywords
- virus
- seq
- rest
- peptide
- ige
- Prior art date
Links
- 229940023041 peptide vaccine Drugs 0.000 title 1
- 241000700605 Viruses Species 0.000 abstract 6
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 6
- 230000002163 immunogen Effects 0.000 abstract 5
- 230000000890 antigenic effect Effects 0.000 abstract 3
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 2
- 239000004472 Lysine Substances 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 101710132601 Capsid protein Proteins 0.000 abstract 1
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 235000018417 cysteine Nutrition 0.000 abstract 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6075—Viral proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
SE REFIERE A UN INMUNOGENO QUE COMPRENDE UN PEPTIDO DE IgE ANTIGENICO UNIDO A UN VEHICULO INMUNOGENICO, EN EL QUE DICHO PEPTIDO IgE ANTIGENICO COMPRENDE LA SECUENCIA DE AMINOACIDOS SEC ID Nº: 311, 312, 313, 314, 315, 316, 425, 426, 427, 428, 429, 430, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 92, 93, 94, 95, 96, 97, 98, 99, ENTRE OTROS; Y EL VEHICULO INMUNOGENICO ES UNA PARTICULA DE VIRUS TAL COMO VLP DE HBcAg, HBsAg Y Qbeta. TAMBIEN SE REFIERE A UNA COMPOSICION QUE COMPRENDE DOS INMUNOGENOS: A) EL PRIMER INMUNOGENO CONTIENE UN PEPTIDO DE IgE ANTIGENICO DE LA SEC ID Nº: 220 ENTRECRUZADO QUIMICAMENTE CON UN VIRUS DE Qbeta DE LA SEC ID Nº: 435 MEDIANTE UN ENLACE TIOETER, SIENDO DICHO ENLACE ENTRE UN RESTO DE LISINA DEL VIRUS Y EL RESTO DE CISTEINA DE DICHO PEPTIDO; Y B) EL SEGUNDO INMUNOGENO CONTIENE UN POLIPEPTIDO DE LA SEC ID Nº: 457 ENTRECRUZADO QUIMICAMENTE CON UN VIRUS DE Qbeta DE LA SEC ID Nº: 435 MEDIANTE UN ENLACE TIOETER, SIENDO DICHO ENLACE ENTRE UN RESTO DE LISINA DEL VIRUS Y EL RESTO DE CISTEINA DE DICHO POLIPEPTIDO. DICHA COMPOSICION ES UTIL EN EL TRATAMIENTO DE ASMA
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12098908P | 2008-12-09 | 2008-12-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20110891A1 true PE20110891A1 (es) | 2011-12-23 |
Family
ID=42035836
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2014000753A PE20142330A1 (es) | 2008-12-09 | 2009-12-04 | Vacuna de peptido ch3 de ige |
PE2011001186A PE20110891A1 (es) | 2008-12-09 | 2009-12-04 | Vacuna de peptido ch3 de ige |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2014000753A PE20142330A1 (es) | 2008-12-09 | 2009-12-04 | Vacuna de peptido ch3 de ige |
Country Status (22)
Country | Link |
---|---|
US (3) | US8298547B2 (es) |
EP (2) | EP2865389A1 (es) |
JP (4) | JP5209800B2 (es) |
KR (3) | KR101413844B1 (es) |
CN (1) | CN102245198B (es) |
AR (1) | AR074505A1 (es) |
AU (1) | AU2009325950B2 (es) |
BR (1) | BRPI0922561A2 (es) |
CA (1) | CA2744754A1 (es) |
CO (1) | CO6561830A2 (es) |
DK (1) | DK2376108T3 (es) |
ES (1) | ES2622562T3 (es) |
HK (1) | HK1163511A1 (es) |
IL (1) | IL213029A0 (es) |
MX (2) | MX337723B (es) |
NZ (2) | NZ592977A (es) |
PE (2) | PE20142330A1 (es) |
RU (1) | RU2495049C2 (es) |
SG (2) | SG10201400388QA (es) |
TW (1) | TWI387463B (es) |
WO (1) | WO2010067286A2 (es) |
ZA (1) | ZA201104072B (es) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2594591B1 (en) * | 2005-08-11 | 2018-06-06 | Arpi Matossian-Rogers | Tcr-v-beta related peptides for treatment and diagnosis of autoimmune disease |
US8552165B2 (en) * | 2008-12-09 | 2013-10-08 | Heather Davis | Immunostimulatory oligonucleotides |
RU2477753C2 (ru) | 2008-12-09 | 2013-03-20 | Коули Фармасьютикал Груп, Инк. | Иммуностимулирующие олигонуклеотиды |
WO2011154878A1 (en) * | 2010-06-07 | 2011-12-15 | Pfizer Vaccines Llc | Ige ch3 peptide vaccine |
EP2471926A3 (en) * | 2010-12-30 | 2012-07-11 | Intervet International BV | Immunostimulatory oligodeoxynucleotides |
BR112013029968A2 (pt) * | 2011-05-26 | 2017-01-31 | Intervet Int Bv | oligodesoxinucleotídeo imunoestimulatório não metilado, vetor, vacina para prevenir ou combater uma doença infecciosa, e, método para a detecção de oligodesoxinucleotídeos imunoestimulatórios |
CA2834440A1 (en) | 2011-05-26 | 2012-11-29 | Intervet International B.V. | Immunostimulatory oligodeoxynucleotides |
EP2804624B1 (en) | 2012-01-19 | 2018-12-26 | Duke University | Vaccines against antigens involved in therapy resistance and methods of using same |
US9187553B2 (en) * | 2012-01-25 | 2015-11-17 | Swey-Shen Chen | Displaying native human IgE neutralizing FcepsilonRIa-contacting IgE B-cell epitopes by constraining super beta(b)-strands and cystine knots on thermostable protein scaffold |
WO2013191166A1 (ja) | 2012-06-18 | 2013-12-27 | 日本全薬工業株式会社 | IgEペプチドワクチン |
EP3166646A4 (en) | 2014-07-07 | 2018-03-07 | Duke University | Vaccines against an oncogenic isoform of her2 (erbb2) and methods of using the same |
EP3166630A4 (en) | 2014-07-07 | 2018-03-28 | Duke University | Vaccines against an oncogenic isoform of esr1 and methods of using the same |
WO2016005545A1 (en) | 2014-07-10 | 2016-01-14 | Affiris Ag | Substances and methods for the use in prevention and/or treatment in huntington's disease |
AU2016332266B2 (en) * | 2015-09-30 | 2020-05-07 | Shionogi & Co., Ltd. | Nucleic acid derivative having immunostimulatory activity |
KR101876620B1 (ko) * | 2015-10-27 | 2018-07-09 | 대구한의대학교산학협력단 | 펩타이드 기반 분자결합자를 이용한 노로바이러스 검출칩 및 그 제작방법 |
WO2017120576A1 (en) | 2016-01-07 | 2017-07-13 | Duke University | Cancer vaccines and methods of delivery |
US11224665B2 (en) | 2016-10-05 | 2022-01-18 | Duke University | Mitochondrial antiviral signaling (MAVS) protein compositions and methods of using the same |
US10487143B2 (en) | 2016-10-05 | 2019-11-26 | Duke University | Vaccines against HER3 antigens and methods of using the same |
SG11201908059YA (en) * | 2017-03-29 | 2019-10-30 | Shionogi & Co | Nucleic acid derivative having immunostimulatory activity |
JP2023542036A (ja) | 2020-09-17 | 2023-10-04 | ネオヴァクス | IgE介在性炎症性障害を治療するためのIgEフラグメントを含む免疫原性産物 |
WO2023192203A2 (en) * | 2022-03-28 | 2023-10-05 | The Regents Of The University Of California | Novel plant virus and bacteriophage vaccines |
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