PE20110327A1 - Vacuna contra el virus de papiloma humano - Google Patents

Vacuna contra el virus de papiloma humano

Info

Publication number
PE20110327A1
PE20110327A1 PE2011000104A PE2011000104A PE20110327A1 PE 20110327 A1 PE20110327 A1 PE 20110327A1 PE 2011000104 A PE2011000104 A PE 2011000104A PE 2011000104 A PE2011000104 A PE 2011000104A PE 20110327 A1 PE20110327 A1 PE 20110327A1
Authority
PE
Peru
Prior art keywords
human papilloma
papilloma virus
against human
vaccine against
vaccine
Prior art date
Application number
PE2011000104A
Other languages
English (en)
Inventor
Dominique Descamps
Sandra Giannini
Nicolas Lecrenier
Jean Stephenne
Martine Anne Cecile Wettendorff
Original Assignee
Glaxosmithkline Biolog Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa
Publication of PE20110327A1 publication Critical patent/PE20110327A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

SE REFIERE A UNA VACUNA QUE COMPRENDE: A) PARTICULAS SIMILARES A VIRUS (VLPs) DEL VIRUS DE PAPILOMA HUMANO HPV 16 Y HPV 18 EN UNA CANTIDAD DE 20ug O 40ug CADA UNO; Y B) UN ADYUVANTE TAL COMO HIDROXIDO DE ALUMINIO Y EL LIPIDO A DE 3-O-DESACIL-4'-MONOFOSFORILO (3D-MPL). DONDE DICHA VACUNA SE ADMINISTRA EN DOS DOSIS SIENDO UTIL EN EL TRATAMIENTO DE LA INFECCION PRODUCIDA POR EL VIRUS DE PAPILOMA HUMANO EN MUJERES CON EDADES DE 25 ANOS O MENOS
PE2011000104A 2008-07-31 2009-07-29 Vacuna contra el virus de papiloma humano PE20110327A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8510108P 2008-07-31 2008-07-31
US17656109P 2009-05-08 2009-05-08

Publications (1)

Publication Number Publication Date
PE20110327A1 true PE20110327A1 (es) 2011-06-29

Family

ID=41139260

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2011000104A PE20110327A1 (es) 2008-07-31 2009-07-29 Vacuna contra el virus de papiloma humano

Country Status (26)

Country Link
US (1) US20110189229A1 (es)
EP (1) EP2318042B1 (es)
JP (1) JP6022159B2 (es)
KR (1) KR20110053340A (es)
CN (1) CN102159239A (es)
AU (1) AU2009275909A1 (es)
BR (1) BRPI0916732B1 (es)
CA (1) CA2732436C (es)
CO (1) CO6341567A2 (es)
DK (1) DK2318042T3 (es)
DO (1) DOP2011000031A (es)
EA (1) EA201170264A1 (es)
ES (1) ES2519490T3 (es)
HR (1) HRP20141063T1 (es)
IL (1) IL210977A0 (es)
MA (1) MA32554B1 (es)
MX (1) MX2011001218A (es)
NZ (1) NZ590919A (es)
PE (1) PE20110327A1 (es)
PL (1) PL2318042T3 (es)
PT (1) PT2318042E (es)
RS (1) RS53607B1 (es)
SI (1) SI2318042T1 (es)
SM (1) SMT201400170B (es)
WO (1) WO2010012780A1 (es)
ZA (1) ZA201100889B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102497880A (zh) 2009-06-25 2012-06-13 葛兰素史密丝克莱恩生物有限公司 新的人***状瘤病毒(hpv)蛋白构建体及其在预防hpv疾病中的用途
CN102178944A (zh) * 2010-09-17 2011-09-14 大连雅立峰生物制药有限公司 人***瘤病毒16和18型l1蛋白在昆虫细胞中的表达及应用
CN102229660B (zh) * 2011-05-25 2015-04-22 厦门大学 截短的人***瘤病毒33型l1蛋白
KR101559622B1 (ko) * 2012-07-30 2015-10-13 중앙대학교 산학협력단 인유두종바이러스 바이러스 유사입자의 고효율 정제방법
AU2015313756A1 (en) * 2014-09-11 2017-03-09 Cadila Healthcare Limited Superior human papilloma virus antigens with superior immunological properties and vaccine containing it
RU2628693C1 (ru) * 2016-11-10 2017-08-21 федеральное государственное бюджетное учреждение "Федеральный научно-исследовательский центр эпидемиологии и микробиологии имени почетного академика Н.Ф. Гамалеи" Министерства здравоохранения Российской Федерации (ФГБУ "ФНИЦЭМ им. Н.Ф. Гамалеи" Минздрава России) РЕКОМБИНАНТНЫЙ ГЕН L1HPV16, РЕКОМБИНАНТНАЯ ПЛАЗМИДА pQE-L1/16, БЕЛОК L1HPV16 И ИХ ПРИМЕНЕНИЕ

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9921146D0 (en) * 1999-09-07 1999-11-10 Smithkline Beecham Biolog Novel composition
WO2005089164A2 (en) * 2003-12-31 2005-09-29 Pharmexa Inc. Inducing cellular immune responses to human papillomavirus using peptide and nucleic acid compositions
BRPI0512042B8 (pt) * 2004-06-16 2021-05-25 Glaxosmithkline Biologicals Sa composição imunogênica, vacina, uso de uma composição ou vacina, método para produzir uma composição imunogênica, e, uso de vlps ou capsômeros de hpv 16 e 18 com vlps ou capsômeros de pelo menos um outro hpv do tipo causador de câncer
US7758866B2 (en) * 2004-06-16 2010-07-20 Glaxosmithkline Biologicals, S.A. Vaccine against HPV16 and HPV18 and at least another HPV type selected from HPV 31, 45 or 52
EP1877086A2 (en) * 2005-04-26 2008-01-16 GlaxoSmithKline Biologicals SA Vaccine

Also Published As

Publication number Publication date
AU2009275909A1 (en) 2010-02-04
US20110189229A1 (en) 2011-08-04
RS53607B1 (en) 2015-04-30
SI2318042T1 (sl) 2014-12-31
BRPI0916732B1 (pt) 2021-06-29
PT2318042E (pt) 2014-11-05
JP6022159B2 (ja) 2016-11-09
KR20110053340A (ko) 2011-05-20
IL210977A0 (en) 2011-04-28
CA2732436A1 (en) 2010-02-04
DK2318042T3 (da) 2014-11-10
EP2318042A1 (en) 2011-05-11
DOP2011000031A (es) 2011-02-28
WO2010012780A1 (en) 2010-02-04
JP2011529475A (ja) 2011-12-08
CN102159239A (zh) 2011-08-17
EP2318042B1 (en) 2014-08-20
NZ590919A (en) 2012-10-26
BRPI0916732A2 (pt) 2017-01-31
MX2011001218A (es) 2011-03-15
ES2519490T3 (es) 2014-11-07
MA32554B1 (fr) 2011-08-01
CA2732436C (en) 2018-01-16
PL2318042T3 (pl) 2015-02-27
SMT201400170B (it) 2015-01-15
EA201170264A1 (ru) 2011-08-30
ZA201100889B (en) 2012-04-25
HRP20141063T1 (hr) 2015-01-02
CO6341567A2 (es) 2011-11-21

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