PE20070245A1 - Procedimiento para la sintesis de haluros de sulfonilo y sulfonamidas a partir de sales de acido sulfonico - Google Patents

Procedimiento para la sintesis de haluros de sulfonilo y sulfonamidas a partir de sales de acido sulfonico

Info

Publication number
PE20070245A1
PE20070245A1 PE2006000883A PE2006000883A PE20070245A1 PE 20070245 A1 PE20070245 A1 PE 20070245A1 PE 2006000883 A PE2006000883 A PE 2006000883A PE 2006000883 A PE2006000883 A PE 2006000883A PE 20070245 A1 PE20070245 A1 PE 20070245A1
Authority
PE
Peru
Prior art keywords
procedure
sulfonamides
synthesis
sulfonyl halides
ion
Prior art date
Application number
PE2006000883A
Other languages
English (en)
Inventor
Ronald S Michalad
Jean L Helom
Joseph Zeldis
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of PE20070245A1 publication Critical patent/PE20070245A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
    • C07C303/22—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof from sulfonic acids, by reactions not involving the formation of sulfo or halosulfonyl groups; from sulfonic halides by reactions not involving the formation of halosulfonyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/38—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reaction of ammonia or amines with sulfonic acids, or with esters, anhydrides, or halides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/42—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/07—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

REFERIDA A UN PROCEDIMIENTO DE PREPARACION DE HALUROS DE SULFONILO Y SULFONAMIDAS, DONDE DICHO PROCEDIMIENTO CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) TAL COMO [Ar-(R)z-SO3-1]qM, CON UN REACTIVO DE SUSTITUCION HALOGENO EN PRESENCIA DE UNA CANTIDAD CATALITICA DE AGUA, UN SOLVENTE Y EN LA PRESENCIA DE UN CO-CATALIZADOR, POR UN TIEMPO DETERMINADO Y BAJO CONDICIONES ADECUADAS PARA FORMAR UN COMPUESTO DE FORMULA (III) TAL COMO Ar-(R)z-SO2-X; DONDE Ar ES ALQUILO C1-C18, ALQUENILO C2-C18, ALQUINILO C2-C18, ENTRE OTROS; R ES ALQUILENILO C1-C6, ENTRE OTROS; M ES UN ION METALICO DEL GRUPO I O DEL GRUPO II, TAL COMO ION Na+ O ION K+; q ES 1 O 2; X ES HALOGENO. EL SOLVENTE PUEDE SER TETRAHIDROFURANO, ACETONITRILO, ACETONA, ENTRE OTROS; EL CO-CATALIZADOR ES N,N-DIMETILFORMAMIDA Y EL REACTIVO DE SUSTITUCION PUEDE SER SOCl2, POCl3, CLORURO DE OXALILO, ENTRE OTROS. LOS COMPUESTOS PREPARADOS CON ESTE PROCEDIMIENTO SON INTERMEDIARIOS EN LA SINTESIS DE CIERTOS INHIBIDORES cPLA2
PE2006000883A 2005-07-21 2006-07-21 Procedimiento para la sintesis de haluros de sulfonilo y sulfonamidas a partir de sales de acido sulfonico PE20070245A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US70115805P 2005-07-21 2005-07-21

Publications (1)

Publication Number Publication Date
PE20070245A1 true PE20070245A1 (es) 2007-03-26

Family

ID=37571383

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2006000883A PE20070245A1 (es) 2005-07-21 2006-07-21 Procedimiento para la sintesis de haluros de sulfonilo y sulfonamidas a partir de sales de acido sulfonico

Country Status (23)

Country Link
US (1) US7842834B2 (es)
EP (1) EP1907355B1 (es)
JP (1) JP4926172B2 (es)
KR (1) KR20080027868A (es)
CN (1) CN101228118B (es)
AR (1) AR057676A1 (es)
AU (1) AU2006272886B2 (es)
BR (1) BRPI0614005A2 (es)
CA (1) CA2610228C (es)
CR (1) CR9581A (es)
EC (1) ECSP088116A (es)
ES (1) ES2556620T3 (es)
GT (1) GT200600325A (es)
IL (1) IL187711A (es)
MX (1) MX2008000816A (es)
NI (1) NI200800018A (es)
NO (1) NO20076358L (es)
PE (1) PE20070245A1 (es)
RU (1) RU2466983C2 (es)
SG (1) SG163550A1 (es)
TW (1) TW200728262A (es)
WO (1) WO2007013974A2 (es)
ZA (1) ZA200800557B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR048239A1 (es) 2004-02-25 2006-04-12 Wyeth Corp Procesos para la preparacion de haluros de aril- y heteroaril-alquilsulfonilo e intermediarios de sintesis de los mismos
US7842834B2 (en) 2005-07-21 2010-11-30 Wyeth Llc Process for the synthesis of sulfonyl halides and sulfonamides from sulfonic acid salts
TW201036941A (en) * 2009-03-30 2010-10-16 Sumitomo Chemical Co Method for producing sulfonamide compound
CN102887841A (zh) * 2012-11-02 2013-01-23 天津希恩思生化科技有限公司 化合物丹磺酰氯的制备方法
CN109722230B (zh) * 2017-10-27 2021-07-23 中石化石油工程技术服务有限公司 一种油基钻井液用乳化剂及其制备方法和钻井液
CN112110863A (zh) * 2020-08-27 2020-12-22 中山大学 一种磺酰氟类化合物、其制备方法以及通过其制备磺酰胺类化合物的方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE150313C (es)
DE48722C (de) Dr. E. FISCHER in Stuttgart, Schlofsstrafse 29 Verfahren zur Darstellung von O-Nitrobenzaldehyd aus O-Nitrobenzylchlorid
US2199568A (en) 1938-06-11 1940-05-07 Gen Aniline & Film Corp Manufacture of 1-methyl-4-chloro-5-hydroxynaphthalene-11-sulphonic acid
US2507408A (en) 1948-03-05 1950-05-09 Rhone Poulenc Sa 1-alkylsulfonyl-4-alkyl piperazines
US2888486A (en) * 1953-11-20 1959-05-26 Du Pont Process for producing aromatic sulfonyl halides
US4885027A (en) * 1985-04-05 1989-12-05 Chevron Research Company Herbicidal arylmethylenesulfonamido-acetamide and thioacetamide derivatives
JPS6310795A (ja) * 1986-03-25 1988-01-18 Takeda Chem Ind Ltd 選択性除草化合物
JP3814696B2 (ja) * 1995-04-17 2006-08-30 住友精化株式会社 芳香族またはヘテロ芳香族スルホニルハライド類の製造方法
JPH11292865A (ja) * 1998-04-03 1999-10-26 Ono Pharmaceut Co Ltd 医薬品の中間体の製造方法
AU2000264717A1 (en) * 1999-08-03 2001-02-19 Kureha Kagaku Kogyo K K N-(benzylsulfonyl)picolinamide derivatives, process for the preparation thereof and herbicides
FR2802121A1 (fr) * 1999-12-14 2001-06-15 Expansia Sa Supports polymeriques organiques possedant des ligands mono- ou bi-dentates et leur utilisation en catalyse supportee
DK1892239T3 (da) * 2001-12-03 2013-03-25 Wyeth Llc Inhibitorer af cytosol-phospholipase A2
SI1656370T1 (sl) * 2003-06-03 2012-12-31 Rib-X Pharmaceuticals, Inc. Biarilne heterociklične spojine in postopki za njihovo izdelavo in uporabo
AR048239A1 (es) 2004-02-25 2006-04-12 Wyeth Corp Procesos para la preparacion de haluros de aril- y heteroaril-alquilsulfonilo e intermediarios de sintesis de los mismos
US7842834B2 (en) 2005-07-21 2010-11-30 Wyeth Llc Process for the synthesis of sulfonyl halides and sulfonamides from sulfonic acid salts
EP2337672B1 (en) * 2008-10-22 2018-02-28 Cytec Technology Corporation Improved processing of polymer matrix composites

Also Published As

Publication number Publication date
AR057676A1 (es) 2007-12-12
RU2007149184A (ru) 2009-08-27
JP4926172B2 (ja) 2012-05-09
GT200600325A (es) 2007-02-26
CN101228118A (zh) 2008-07-23
CR9581A (es) 2008-03-06
CA2610228A1 (en) 2007-02-01
NI200800018A (es) 2009-03-03
US7842834B2 (en) 2010-11-30
NO20076358L (no) 2008-04-16
WO2007013974A3 (en) 2007-04-12
AU2006272886B2 (en) 2012-03-01
CA2610228C (en) 2014-02-18
BRPI0614005A2 (pt) 2011-03-01
ES2556620T3 (es) 2016-01-19
AU2006272886A1 (en) 2007-02-01
CN101228118B (zh) 2013-09-18
US20070021614A1 (en) 2007-01-25
SG163550A1 (en) 2010-08-30
MX2008000816A (es) 2008-03-18
JP2009502802A (ja) 2009-01-29
RU2466983C2 (ru) 2012-11-20
WO2007013974A2 (en) 2007-02-01
ZA200800557B (en) 2011-06-26
IL187711A (en) 2016-04-21
IL187711A0 (en) 2008-08-07
TW200728262A (en) 2007-08-01
ECSP088116A (es) 2008-02-20
EP1907355A2 (en) 2008-04-09
KR20080027868A (ko) 2008-03-28
EP1907355B1 (en) 2015-08-05

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