PE20050189A1 - Composiciones que comprenden derivados de acido quinoloncarboxilico para administracion local - Google Patents
Composiciones que comprenden derivados de acido quinoloncarboxilico para administracion localInfo
- Publication number
- PE20050189A1 PE20050189A1 PE2004000145A PE2004000145A PE20050189A1 PE 20050189 A1 PE20050189 A1 PE 20050189A1 PE 2004000145 A PE2004000145 A PE 2004000145A PE 2004000145 A PE2004000145 A PE 2004000145A PE 20050189 A1 PE20050189 A1 PE 20050189A1
- Authority
- PE
- Peru
- Prior art keywords
- local administration
- quinoloncarboxyl
- acid derivatives
- compositions including
- refers
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 abstract 3
- MYSWGUAQZAJSOK-UHFFFAOYSA-N ciprofloxacin Chemical compound C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 MYSWGUAQZAJSOK-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- SPFYMRJSYKOXGV-UHFFFAOYSA-N Baytril Chemical compound C1CN(CC)CCN1C(C(=C1)F)=CC2=C1C(=O)C(C(O)=O)=CN2C1CC1 SPFYMRJSYKOXGV-UHFFFAOYSA-N 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 229960003237 betaine Drugs 0.000 abstract 1
- 229960003405 ciprofloxacin Drugs 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229960000740 enrofloxacin Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Otolaryngology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Quinoline Compounds (AREA)
Abstract
SE REFIERE A COMPOSICIONES QUE COMPRENDEN DERIVADOS DE ACIDO QUINOLONCARBOXILICO (CIPROFLOXACINO, ENROFLOXACINO) DE ADMINISTRACION LOCAL, PRESENTADAS EN LA FORMA DE BETAINA SOLIDA Y/O COMO SAL DE BETAINA SOLIDA ESCASAMENTE SOLUBLE , PREFERENTEMENTE COMO EMBONATOS (TAMBIEN CONOCIDOS COMO PAMOATOS). EL USO DE ESTOS COMPUESTOS PARA LA FABRICACION DE MEDICAMENTOS DE ADMINISTRACION LOCAL PARA EL TRATAMIENTO ENFERMEDADES BACTERIANAS DE LOS ORGANOS RESPIRATORIOS EN HOMBRES Y ANIMALES. TAMBIEN SE REFIERA A DISPOSITIVOS QUE SON APROPIADOS PARA LA ADMINISTACION INHALATORIA DEL PRINCIPIO ACTIVO SOLIDO Y CONTIENE PREPARADOS CON AL MENOS UNO DE LOS COMPUESTOS DEFINIDOS ANTERIORMENTE
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10305318A DE10305318A1 (de) | 2003-02-10 | 2003-02-10 | Behandlung bakteriell verursachter Lungenkrankheiten |
DE10305319A DE10305319A1 (de) | 2003-02-10 | 2003-02-10 | Behandlung bakteriell verursachter Lungenkrankheiten |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20050189A1 true PE20050189A1 (es) | 2005-05-22 |
Family
ID=32851853
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2004000145A PE20050189A1 (es) | 2003-02-10 | 2004-02-09 | Composiciones que comprenden derivados de acido quinoloncarboxilico para administracion local |
Country Status (28)
Country | Link |
---|---|
US (2) | US8034817B2 (es) |
EP (1) | EP1594500B1 (es) |
JP (2) | JP4828405B2 (es) |
KR (1) | KR101173696B1 (es) |
AR (1) | AR043117A1 (es) |
AT (1) | ATE482706T1 (es) |
AU (1) | AU2004210399B2 (es) |
BR (1) | BRPI0407368A (es) |
CA (1) | CA2515262C (es) |
CY (1) | CY1110998T1 (es) |
DE (1) | DE502004011696D1 (es) |
DK (1) | DK1594500T3 (es) |
EC (1) | ECSP055959A (es) |
HK (1) | HK1089380A1 (es) |
HR (1) | HRP20050786B1 (es) |
IL (1) | IL170027A (es) |
MA (1) | MA27632A1 (es) |
MX (1) | MXPA05008407A (es) |
MY (1) | MY144714A (es) |
NO (1) | NO331524B1 (es) |
NZ (1) | NZ541681A (es) |
PE (1) | PE20050189A1 (es) |
PT (1) | PT1594500E (es) |
RU (1) | RU2373937C9 (es) |
SI (1) | SI1594500T1 (es) |
TW (1) | TWI347843B (es) |
UY (1) | UY28179A1 (es) |
WO (1) | WO2004069253A1 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0407368A (pt) * | 2003-02-10 | 2006-02-14 | Bayer Healthcare Ag | tratamento de doenças bacterianas dos órgãos respiratórios mediante aplicação local e fluor-quinolonas. |
US7157455B2 (en) * | 2003-02-10 | 2007-01-02 | Hoffmann-La Roche Inc. | 4-Aminopyrimidine-5-one derivatives |
WO2006033713A2 (en) * | 2004-08-09 | 2006-03-30 | Chiron Corporation | Methods for ciprofloxacin inhalation |
BRPI0517374A (pt) * | 2004-10-29 | 2008-10-07 | Harvard College | formulação para tratamento ou prevenção de infecção respiratória, método para tratamento |
US8546423B2 (en) | 2005-05-18 | 2013-10-01 | Mpex Pharmaceuticals, Inc. | Aerosolized fluoroquinolones and uses thereof |
CN101222927B (zh) * | 2005-05-18 | 2016-08-24 | 拉普特制药有限公司 | 气溶胶化的氟喹诺酮类药物及其应用 |
BRPI0913021A2 (pt) * | 2008-05-15 | 2015-10-13 | Novartis Ag | distribuição pulmonar de uma fluoroquinolona |
CN102325532B (zh) | 2008-10-07 | 2015-06-17 | Mpex医药有限公司 | 用于减轻肺部炎症的左氧氟沙星吸入剂 |
NZ631469A (en) | 2008-10-07 | 2016-06-24 | Raptor Pharmaceuticals Inc | Aerosol fluoroquinolone formulations for improved pharmacokinetics |
US8168597B2 (en) | 2008-10-22 | 2012-05-01 | Inspire Pharmaceuticals, Inc. | Method for treating cystic fibrosis |
LT2473170T (lt) | 2009-09-04 | 2019-10-10 | Horizon Orphan Llc | Aerozolizuoto levofloksacino panaudojimas cistinės fibrozės gydymui |
US9393243B1 (en) | 2015-07-14 | 2016-07-19 | Nilesh Parikh | Topical Ciprofloxacin compositions |
WO2018074880A2 (ko) * | 2016-10-20 | 2018-04-26 | 한국화학연구원 | 퀴놀린 4-온 유도체 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 포함하는 폐렴의 예방 또는 치료용 약학적 조성물 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4670444B1 (en) * | 1980-09-03 | 1999-02-09 | Bayer Ag | and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds |
DE3033157A1 (de) | 1980-09-03 | 1982-04-01 | Bayer Ag, 5090 Leverkusen | 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
DE3525335A1 (de) * | 1985-07-16 | 1987-01-22 | Bayer Ag | Embonate von chinoloncarbonsaeuren und ihren derivaten |
DE3906365A1 (de) | 1988-07-15 | 1990-01-18 | Bayer Ag | 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe |
FR2655545B1 (fr) * | 1989-12-11 | 1994-06-10 | Rhone Poulenc Sante | Nouvelle application therapeutique des derives des fluoroquinolones. |
EP0504112A3 (en) * | 1991-03-14 | 1993-04-21 | Ciba-Geigy Ag | Pharmaceutical aerosol formulations |
DE4200821A1 (de) * | 1992-01-15 | 1993-07-22 | Bayer Ag | Geschmacksmaskierte pharmazeutische mittel |
DE19633480A1 (de) * | 1996-08-20 | 1998-02-26 | Bayer Ag | Oral applizierbare Formulierungen von Chinolon- und Naphthyridoncarbonsäuren |
DE19812160C1 (de) * | 1998-03-20 | 1999-07-08 | Bayer Ag | Formkörper aus wirkstoffhaltigen thermoplastischen Polyurethanen |
WO2000015207A2 (en) * | 1998-09-15 | 2000-03-23 | Naeja Pharmaceutical Inc. | Combination for the treatment of inflammation using elastine inhibitor(s) and antibacterial agent(s) |
ES2343124T3 (es) * | 1999-10-29 | 2010-07-23 | Novartis Ag | Composiciones de polvo seco con dispersabilidad mejorada. |
DE19962470A1 (de) | 1999-12-22 | 2001-07-12 | Schulz Hans Herrmann | Verwendung von Chemotherapeutika |
DE10031043A1 (de) * | 2000-06-26 | 2002-02-14 | Bayer Ag | Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung |
CA2477979A1 (en) * | 2002-03-05 | 2003-09-18 | Transave, Inc. | An inhalation system for treatment of intracellular infections |
CA2483218C (en) * | 2002-04-25 | 2012-07-10 | Nektar Therapeutics Uk Ltd | Particulate materials |
BRPI0407368A (pt) * | 2003-02-10 | 2006-02-14 | Bayer Healthcare Ag | tratamento de doenças bacterianas dos órgãos respiratórios mediante aplicação local e fluor-quinolonas. |
-
2004
- 2004-01-28 BR BRPI0407368-1A patent/BRPI0407368A/pt not_active Application Discontinuation
- 2004-01-28 EP EP04705765A patent/EP1594500B1/de not_active Expired - Lifetime
- 2004-01-28 KR KR1020057014646A patent/KR101173696B1/ko active IP Right Grant
- 2004-01-28 DE DE502004011696T patent/DE502004011696D1/de not_active Expired - Lifetime
- 2004-01-28 SI SI200431572T patent/SI1594500T1/sl unknown
- 2004-01-28 NZ NZ541681A patent/NZ541681A/en not_active IP Right Cessation
- 2004-01-28 WO PCT/EP2004/000710 patent/WO2004069253A1/de active Application Filing
- 2004-01-28 JP JP2006501628A patent/JP4828405B2/ja not_active Expired - Fee Related
- 2004-01-28 AU AU2004210399A patent/AU2004210399B2/en not_active Ceased
- 2004-01-28 CA CA2515262A patent/CA2515262C/en not_active Expired - Fee Related
- 2004-01-28 RU RU2005128132/14A patent/RU2373937C9/ru not_active IP Right Cessation
- 2004-01-28 PT PT04705765T patent/PT1594500E/pt unknown
- 2004-01-28 DK DK04705765.8T patent/DK1594500T3/da active
- 2004-01-28 MX MXPA05008407A patent/MXPA05008407A/es active IP Right Grant
- 2004-01-28 AT AT04705765T patent/ATE482706T1/de active
- 2004-02-06 UY UY28179A patent/UY28179A1/es not_active Application Discontinuation
- 2004-02-06 AR ARP040100382A patent/AR043117A1/es unknown
- 2004-02-06 MY MYPI20040367A patent/MY144714A/en unknown
- 2004-02-09 TW TW093102878A patent/TWI347843B/zh not_active IP Right Cessation
- 2004-02-09 PE PE2004000145A patent/PE20050189A1/es not_active Application Discontinuation
- 2004-02-10 US US10/775,888 patent/US8034817B2/en not_active Expired - Fee Related
-
2005
- 2005-08-02 IL IL170027A patent/IL170027A/en active IP Right Grant
- 2005-08-10 EC EC2005005959A patent/ECSP055959A/es unknown
- 2005-09-08 NO NO20054180A patent/NO331524B1/no not_active IP Right Cessation
- 2005-09-08 HR HRP20050786AA patent/HRP20050786B1/hr not_active IP Right Cessation
- 2005-09-09 MA MA28491A patent/MA27632A1/fr unknown
-
2006
- 2006-09-07 HK HK06109963.8A patent/HK1089380A1/xx not_active IP Right Cessation
-
2010
- 2010-12-17 CY CY20101101161T patent/CY1110998T1/el unknown
-
2011
- 2011-06-08 JP JP2011128600A patent/JP2011173929A/ja active Pending
- 2011-07-28 US US13/192,893 patent/US20120010215A1/en not_active Abandoned
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Refusal |