PE20030689A1 - Nuevas formas cristalinas anhidras de la gabapentina - Google Patents
Nuevas formas cristalinas anhidras de la gabapentinaInfo
- Publication number
- PE20030689A1 PE20030689A1 PE2002000988A PE2002000988A PE20030689A1 PE 20030689 A1 PE20030689 A1 PE 20030689A1 PE 2002000988 A PE2002000988 A PE 2002000988A PE 2002000988 A PE2002000988 A PE 2002000988A PE 20030689 A1 PE20030689 A1 PE 20030689A1
- Authority
- PE
- Peru
- Prior art keywords
- gabapentin
- dehydrated
- refers
- monohydrate
- crystalline
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE REFIERE A UN PROCESO PARA LA PREPARACION DE LA FORMA B CRISTALINA DESHIDRATADA DE GABAPENTINA QUE COMPRENDE: a) DESHIDRATAR LA GABAPENTINA MONOHIDRATO PARA FORMAR LA FORMA A CRISTALINA DESHIDRATADA DE GABAPENTINA Y b) DEJAR QUE LA FORMA A DESHIDRATADA REPOSE A TEMPERATURA AMBIENTE PARA FORMA LA FORMA B CRISTALINA DESHIDRATADA DE GABAPENTINA. EL PROCESO DEL PASO DE DESHIDRATACION (A) SE LLEVA A CABO APLICANDO UN VACIO, UN DESECANTE Y CALOR EN UN AMBIENTE EN EL CUAL LA ACTIVIDAD HIDRICA SE MANTIENE POR DEBAJO DE 0,8 A 0,9 Y UNA TEMPERATURA DE 50°C A 175°C. SE REFIERE TAMBIEN AL PROCESO EN EL CUAL SE PREPARA GABAPENTINA MONOHIDRATO MEDIANTE LOS SIGUIENTE PASOS: a) SUSPENDER GABAPENTINA EN UN SOLVENTE O MEZCLA DE SOLVENTE CON UNA ACTIVIDAD HIDRICA DE 0,8 A 0,9; b) CRISTALIZAR Y RECOGER GABAPENTINA MONOHIDRATO EN UN FILTRO. LA FORMA A DE LA GABAPENTINA DESHIDRATADA CRISTALINA TIENE UNA DIFRACCION DE RAYOS X EN POLVO QUE CONTIENE LOS VALORES DE 2 O MEDIDOS UTILIZANDO RADIACION CuKO: 6,2 12,5 16,1 18,8 19,2 25,1 Y 26, 1. SE REFIERE TAMBIEN A UNA FORMA B DE GABAPENTINA DESHIDRATADA CON UNA DIFRACCION DE RAYOS X EN POLVO CON LOS SIGUIENTES VALORES CuKO: 6,0 o 16,8
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32837501P | 2001-10-09 | 2001-10-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20030689A1 true PE20030689A1 (es) | 2003-08-11 |
Family
ID=34589923
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2002000988A PE20030689A1 (es) | 2001-10-09 | 2002-10-04 | Nuevas formas cristalinas anhidras de la gabapentina |
Country Status (12)
| Country | Link |
|---|---|
| AR (1) | AR036695A1 (es) |
| DO (1) | DOP2002000474A (es) |
| GT (1) | GT200200204A (es) |
| HN (1) | HN2002000283A (es) |
| MY (1) | MY129370A (es) |
| PA (1) | PA8555901A1 (es) |
| PE (1) | PE20030689A1 (es) |
| SV (1) | SV2004001275A (es) |
| TW (1) | TWI245033B (es) |
| UA (1) | UA77021C2 (es) |
| UY (1) | UY27473A1 (es) |
| ZA (1) | ZA200402519B (es) |
-
2002
- 2002-03-10 UA UA20040503407A patent/UA77021C2/uk unknown
- 2002-09-25 TW TW91122057A patent/TWI245033B/zh not_active IP Right Cessation
- 2002-09-27 AR ARP020103664 patent/AR036695A1/es unknown
- 2002-10-01 DO DO2002000474A patent/DOP2002000474A/es unknown
- 2002-10-04 HN HN2002000283A patent/HN2002000283A/es unknown
- 2002-10-04 PE PE2002000988A patent/PE20030689A1/es not_active Application Discontinuation
- 2002-10-04 MY MYPI20023726 patent/MY129370A/en unknown
- 2002-10-07 UY UY27473A patent/UY27473A1/es not_active Application Discontinuation
- 2002-10-08 SV SV2002001275A patent/SV2004001275A/es not_active Application Discontinuation
- 2002-10-09 GT GT200200204A patent/GT200200204A/es unknown
- 2002-10-09 PA PA8555901A patent/PA8555901A1/es unknown
-
2004
- 2004-03-30 ZA ZA200402519A patent/ZA200402519B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR036695A1 (es) | 2004-09-29 |
| TWI245033B (en) | 2005-12-11 |
| ZA200402519B (en) | 2005-01-24 |
| HN2002000283A (es) | 2005-02-22 |
| UY27473A1 (es) | 2003-05-30 |
| DOP2002000474A (es) | 2003-04-15 |
| SV2004001275A (es) | 2004-02-24 |
| UA77021C2 (en) | 2006-10-16 |
| MY129370A (en) | 2007-03-30 |
| PA8555901A1 (es) | 2003-06-30 |
| GT200200204A (es) | 2003-05-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PE20020267A1 (es) | Sales estables de acido o-acetilsalicilico con aminoacidos basicos | |
| AR068527A2 (es) | Un procedimiento para preparar monohidrato de bromuro de tiotropio cristalino | |
| PE20030689A1 (es) | Nuevas formas cristalinas anhidras de la gabapentina | |
| Karabatsos et al. | Carbonium Ion Rearrangements. V. 1 1, 3-Hydride Shifts in the 1-Propyl Cation | |
| CO5570697A2 (es) | Nuevas formas cristalinas anhidras de la gabapentina | |
| ES2195332T3 (es) | Metodo de cristalizacion. | |
| GB1026154A (en) | Allantoin-pantothenate compounds | |
| AR072826A1 (es) | Granulos con alto contenido de ibuprofeno sodico, su preparacion y uso en la preparacion de formas de administracion solidas no efervescentes. proceso. composicion. formulacion. | |
| AR036018A1 (es) | Proceso para aislar monohidrato de imipenem cristalino puro | |
| Lesiecki et al. | Photoproperties of DCM | |
| REICHARD et al. | Enzymic Synthesis of Ureidosuc-cinìc Acid from Citrulline via Compound X and Carbamyl Phosphate | |
| Blinc | The Problem of Negative Anharmonicity and the Nature of the Hydrogen Bond in Potassium Hydrogen Fluoride | |
| Johnston et al. | Liesegang Rings of Ammonium Chloride | |
| Sutherland et al. | Radiolysis of nitrous oxide in the adsorbed state | |
| Smith | The Isomerization of n-Butyl Phenyl Ether | |
| SU376113A1 (ru) | КАТАЛИЗАТОР дл ДЕГИДРАТАЦИИ СПИРТОВ | |
| US2736751A (en) | Process of stabilizing | |
| RU2010134077A (ru) | Способ получения фуллерена c70 | |
| JPS53111079A (en) | Preparation of 2,3-dihydroxydioxane | |
| Matsumoto et al. | Effect of dehydrated nystose addition on the reduction of water activity | |
| BE751188A (fr) | Procede de preparation de benzoate de methyle de grande purete | |
| JPS5315344A (en) | Preparation of 5-cyclohexadecene-1-one | |
| SU683999A1 (ru) | Способ получени кальциевой формы цеолита ен | |
| Oza et al. | The Decomposition of Hyponitrites of Calcium and Strontium. | |
| JPS5234442A (en) | Absorbing freezer of combined single and double effects |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |