NZ333813A - Pharmaceutical composition containing a 5HT2C antagonist and a D2 antagonist - Google Patents

Pharmaceutical composition containing a 5HT2C antagonist and a D2 antagonist

Info

Publication number
NZ333813A
NZ333813A NZ333813A NZ33381397A NZ333813A NZ 333813 A NZ333813 A NZ 333813A NZ 333813 A NZ333813 A NZ 333813A NZ 33381397 A NZ33381397 A NZ 33381397A NZ 333813 A NZ333813 A NZ 333813A
Authority
NZ
New Zealand
Prior art keywords
antagonist
pharmaceutical composition
5ht2c
composition containing
compound
Prior art date
Application number
NZ333813A
Inventor
Thomas Paul Blackburn
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of NZ333813A publication Critical patent/NZ333813A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A pharmaceutical composition for treating or prevention of CNS disorders like schizophrenia comprising: a) a compound having 5HT2c antagonist being 5-methyl-6-trifluoromethyl-1-[6-(2-methylpyridin-3-yloxy)pyridin-3-ylcarbamoyl]indoline, b) a compound having D2 antagonist activity, selected from ziprasidone, olanzapine, sertindole or quetiapine c) a carrier.
NZ333813A 1996-07-26 1997-07-22 Pharmaceutical composition containing a 5HT2C antagonist and a D2 antagonist NZ333813A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9615767.2A GB9615767D0 (en) 1996-07-26 1996-07-26 Novel treatment
PCT/EP1997/004159 WO1998004289A2 (en) 1996-07-26 1997-07-22 Pharmaceutical composition containing a 5ht2c antagonist and a d2 antagonist

Publications (1)

Publication Number Publication Date
NZ333813A true NZ333813A (en) 2000-07-28

Family

ID=10797573

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ333813A NZ333813A (en) 1996-07-26 1997-07-22 Pharmaceutical composition containing a 5HT2C antagonist and a D2 antagonist

Country Status (19)

Country Link
EP (1) EP0936924A2 (en)
JP (1) JP2000516924A (en)
KR (1) KR20000029564A (en)
CN (1) CN1230894A (en)
AR (1) AR008083A1 (en)
AU (1) AU725817B2 (en)
BR (1) BR9710568A (en)
CA (1) CA2261813A1 (en)
CO (1) CO5031292A1 (en)
CZ (1) CZ23799A3 (en)
GB (1) GB9615767D0 (en)
HU (1) HUP9903619A3 (en)
IL (1) IL128219A0 (en)
NO (1) NO990322L (en)
NZ (1) NZ333813A (en)
PL (1) PL331426A1 (en)
TR (1) TR199900140T2 (en)
WO (1) WO1998004289A2 (en)
ZA (1) ZA976593B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9612883D0 (en) * 1996-06-20 1996-08-21 Smithkline Beecham Plc Novel compounds
US6174882B1 (en) 1998-11-23 2001-01-16 Sepracor Inc. 2-hydroxymethylolanzapine compositions and methods
ES2211205T3 (en) * 1998-11-23 2004-07-01 Sepracor Inc. PHARMACEUTICAL COMPOSITIONS CONTAINING OLANZAPINE-N-OXIDE.
PT1133300E (en) 1998-11-23 2005-04-29 Sepracor Inc DESMETILOLANZAPINE COMPOSITIONS AND METHODS
WO2000054764A2 (en) * 1999-03-18 2000-09-21 Children's Hospital Research Foundation A method of treating bulimia nervosa and related eating disorders by administration of atypical antipsychotic medications
CA2363784A1 (en) * 1999-05-19 2000-11-30 Astrazeneca Ab Method of treatment
WO2005013969A1 (en) * 2003-07-15 2005-02-17 Janssen Pharmaceutica N.V. Antipsychotic agent with socializing properties

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9500998D0 (en) * 1995-03-19 1995-03-19 Haakan Wilhelm Wikstroem New sulfone ester analogues of iso-clozapine and related structures: atypical neuroleptics

Also Published As

Publication number Publication date
AR008083A1 (en) 1999-12-09
WO1998004289A2 (en) 1998-02-05
NO990322L (en) 1999-03-24
GB9615767D0 (en) 1996-09-04
JP2000516924A (en) 2000-12-19
CN1230894A (en) 1999-10-06
PL331426A1 (en) 1999-07-19
EP0936924A2 (en) 1999-08-25
IL128219A0 (en) 1999-11-30
AU4297297A (en) 1998-02-20
KR20000029564A (en) 2000-05-25
CA2261813A1 (en) 1998-02-05
TR199900140T2 (en) 1999-03-22
NO990322D0 (en) 1999-01-25
CO5031292A1 (en) 2001-04-27
BR9710568A (en) 1999-08-17
CZ23799A3 (en) 1999-06-16
HUP9903619A3 (en) 2001-03-28
WO1998004289A3 (en) 1998-03-19
AU725817B2 (en) 2000-10-19
HUP9903619A2 (en) 2000-10-28
ZA976593B (en) 1999-01-25

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