NZ244371A - Pyridyl-substituted benzylsulphides and analogues and pharmaceutical compositions - Google Patents

Pyridyl-substituted benzylsulphides and analogues and pharmaceutical compositions

Info

Publication number
NZ244371A
NZ244371A NZ244371A NZ24437192A NZ244371A NZ 244371 A NZ244371 A NZ 244371A NZ 244371 A NZ244371 A NZ 244371A NZ 24437192 A NZ24437192 A NZ 24437192A NZ 244371 A NZ244371 A NZ 244371A
Authority
NZ
New Zealand
Prior art keywords
pyridyl
methoxyphenyl
carboxyethenyl
phenyl
octyloxy
Prior art date
Application number
NZ244371A
Other languages
English (en)
Inventor
Pamela Anne Chambers
Robert A Daines
Dalia R Jakas
William D Kingsbury
Israil Pendrak
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of NZ244371A publication Critical patent/NZ244371A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NZ244371A 1991-09-19 1992-09-17 Pyridyl-substituted benzylsulphides and analogues and pharmaceutical compositions NZ244371A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US76271091A 1991-09-19 1991-09-19
US79093191A 1991-11-12 1991-11-12
US80959391A 1991-12-18 1991-12-18
US93286992A 1992-08-20 1992-08-20
CN93103596A CN1092409A (zh) 1991-09-19 1993-03-19 用于治疗白三烯有关的疾病的化合物

Publications (1)

Publication Number Publication Date
NZ244371A true NZ244371A (en) 1995-11-27

Family

ID=36809157

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ244371A NZ244371A (en) 1991-09-19 1992-09-17 Pyridyl-substituted benzylsulphides and analogues and pharmaceutical compositions

Country Status (12)

Country Link
EP (1) EP0604529A1 (ja)
JP (1) JPH06510786A (ja)
CN (1) CN1092409A (ja)
AP (1) AP333A (ja)
AU (1) AU2573592A (ja)
CA (1) CA2119467A1 (ja)
IL (1) IL103205A0 (ja)
MA (1) MA22649A1 (ja)
MX (1) MX9205358A (ja)
NZ (1) NZ244371A (ja)
PT (1) PT100881A (ja)
WO (1) WO1993006085A1 (ja)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9303972A (es) * 1992-06-30 1994-04-29 Smithkline Beecham Corp Procedimiento para hacer compuestos de tioeter.
GB9313145D0 (en) * 1993-06-25 1993-08-11 Smithkline Beecham Plc Process
IL115420A0 (en) 1994-09-26 1995-12-31 Zeneca Ltd Aminoheterocyclic derivatives
JPH11501038A (ja) * 1995-03-02 1999-01-26 スミスクライン・ビーチャム・コーポレイション アトピー性皮膚炎および接触性皮膚炎の治療方法
GB9508137D0 (en) * 1995-04-21 1995-06-07 Smithkline Beecham Plc Formulation
GB9602166D0 (en) 1996-02-02 1996-04-03 Zeneca Ltd Aminoheterocyclic derivatives
EP0880501A1 (en) 1996-02-02 1998-12-02 Zeneca Limited Heterocyclic compounds useful as pharmaceutical agents
US5929096A (en) * 1996-02-29 1999-07-27 Smithkline Beecham Corporation Method for treating atopic dermatitis and contact dermatitis
PL331599A1 (en) * 1996-08-14 1999-08-02 Zeneca Ltd Substituted derivatives of pyrimidine and their pharmaceutical application
CA2265996A1 (en) * 1996-09-26 1998-04-02 Roger Aki Fujimoto Aryl-substituted acrylamides with leukotriene b4 (ltb-4) receptor antagonist activity
UA56197C2 (uk) 1996-11-08 2003-05-15 Зенека Лімітед Гетероциклічні похідні
JP2001511798A (ja) 1997-02-13 2001-08-14 ゼネカ・リミテッド オキシド−スクアレンシクラーゼ抑制剤として有用な複素環化合物
AU5999798A (en) 1997-02-13 1998-09-08 Zeneca Limited Heterocyclic compounds useful as oxido-squalene cyclase inhibitors
GB9715895D0 (en) 1997-07-29 1997-10-01 Zeneca Ltd Heterocyclic compounds
GB9902989D0 (en) 1999-02-11 1999-03-31 Zeneca Ltd Heterocyclic derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4056619A (en) * 1975-09-08 1977-11-01 Warner-Lambert Company 1-Substituted-2-(2-pyridinyl)ethanone N-oxides
US5004743A (en) * 1987-11-25 1991-04-02 Merck Frosst Canada, Inc. Pyridyl styrene dialkanoic acids as anti-leukotriene agents
HUT64747A (en) * 1990-06-07 1994-02-28 Smithkline Beecham Corp Process for producing benzoic acid derivatives and pharmaceutical preparatives containing them

Also Published As

Publication number Publication date
CN1092409A (zh) 1994-09-21
IL103205A0 (en) 1993-02-21
MA22649A1 (fr) 1993-04-01
MX9205358A (es) 1993-07-01
AP333A (en) 1994-04-25
EP0604529A1 (en) 1994-07-06
PT100881A (pt) 1993-10-29
WO1993006085A1 (en) 1993-04-01
AU2573592A (en) 1993-04-27
AP9200428A0 (en) 1992-10-31
CA2119467A1 (en) 1993-04-01
JPH06510786A (ja) 1994-12-01

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