NO990334D0 - FremgangsmÕte ved fremstilling av 5-[acetyl(2,3-dihydroksypropyl)amino]-N,N'-bis(2,3-dihydroksypropyl)-2,4,6-triiod-1,3-benzendikarboksamid - Google Patents

FremgangsmÕte ved fremstilling av 5-[acetyl(2,3-dihydroksypropyl)amino]-N,N'-bis(2,3-dihydroksypropyl)-2,4,6-triiod-1,3-benzendikarboksamid

Info

Publication number: NO990334D0
Authority: NO; Norway
Prior art keywords: compound; amino; dihydroxypropyl; reaction; triiodo
Prior art date: 1997-05-30

Application number

NO990334A

Other languages

English (en)

Other versions

NO323475B1 (no

NO990334L (no

Inventor

Nicola Desantis

Original Assignee

Bracco Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-05-30

Filing date

1999-01-25

Publication date

1999-01-25

1999-01-25 Application filed by Bracco Spa filed Critical Bracco Spa

1999-01-25 Publication of NO990334D0 publication Critical patent/NO990334D0/no

1999-03-26 Publication of NO990334L publication Critical patent/NO990334L/no

2007-05-21 Publication of NO323475B1 publication Critical patent/NO323475B1/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/08—Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/52—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the nitrogen atom of at least one of the carboxamide groups further acylated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

NO19990334A 1997-05-30 1999-01-25 Fremgangsmate ved fremstilling av 5-[acetyl(2,3-dihydroksypropyl)amino]-N,N'-bis(2,3-dihydroksypropyl)-2,4,6-triiod-1,3-benzendikarboksamid NO323475B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT97MI001268A IT1292037B1 (it)	1997-05-30	1997-05-30	Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen-
PCT/EP1998/002927 WO1998054124A1 (en)	1997-05-30	1998-05-19	A process for the preparation of 5-[acetyl (2,3-dihydroxypropyl)amino]-n,n'-bis (2,3-dihydroxypropyl)-2,4,6- triiodo-1,3-benzenedicarboxamide

Publications (3)

Publication Number	Publication Date
NO990334D0 true NO990334D0 (no)	1999-01-25
NO990334L NO990334L (no)	1999-03-26
NO323475B1 NO323475B1 (no)	2007-05-21

Family

ID=11377250

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19990334A NO323475B1 (no)	1997-05-30	1999-01-25	Fremgangsmate ved fremstilling av 5-[acetyl(2,3-dihydroksypropyl)amino]-N,N'-bis(2,3-dihydroksypropyl)-2,4,6-triiod-1,3-benzendikarboksamid

Country Status (18)

Country	Link
US (1)	US5965772A (no)
EP (1)	EP0915835B1 (no)
JP (1)	JP3437584B2 (no)
KR (1)	KR20000029649A (no)
CN (1)	CN1228079A (no)
AT (1)	ATE198191T1 (no)
AU (1)	AU729759B2 (no)
CA (1)	CA2261656A1 (no)
CZ (1)	CZ25399A3 (no)
DE (1)	DE69800434T2 (no)
DK (1)	DK0915835T3 (no)
ES (1)	ES2152747T3 (no)
GR (1)	GR3035123T3 (no)
IT (1)	IT1292037B1 (no)
NO (1)	NO323475B1 (no)
PL (1)	PL331208A1 (no)
PT (1)	PT915835E (no)
WO (1)	WO1998054124A1 (no)

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SE520688C2 (sv) *	2000-04-11	2003-08-12	Bone Support Ab	Ett injicerbart ersättningsmaterial för benmineral
SE517168C2 (sv) *	2000-07-17	2002-04-23	Bone Support Ab	En komposition för ett injicerbart ersättningsmaterial för benmineral
SE522098C2 (sv)	2001-12-20	2004-01-13	Bone Support Ab	Ett nytt benmineralsubstitut
SE0300620D0 (sv)	2003-03-05	2003-03-05	Bone Support Ab	A new bone substitute composition
WO2004087637A1 (en) *	2003-03-31	2004-10-14	Takasago International Corporation	Production of n-alkylamide compounds
SE0302983D0 (sv) *	2003-11-11	2003-11-11	Bone Support Ab	Anordning för att förse spongiöst ben med benersättnings- och/eller benförstärkningsmaterial och förfarande i samband därmed
SE527528C2 (sv) *	2004-06-22	2006-04-04	Bone Support Ab	Anordning för framställning av härdbar massa samt användning av anordningen
PT103391B (pt) *	2005-11-24	2008-10-30	Hovione Farmaciencia S A	Processo para fabrico de lohexol
CN100344606C (zh) *	2005-12-28	2007-10-24	江苏省原子医学研究所	一种碘昔兰的制备方法
CA2684067A1 (en) *	2007-04-25	2008-11-06	F. Hoffmann-La Roche Ag	Novel process for the preparation of acid chlorides
KR101279751B1 (ko)	2008-04-04	2013-07-04	에프. 호프만-라 로슈 아게	사이클로헥산카복실산 유도체의 제조 방법
KR101290935B1 (ko)	2008-04-04	2013-07-29	에프. 호프만-라 로슈 아게	상응하는 사이클로헥세인카복스아마이드 유도체에 의한 사이클로헥세인카복실산 유도체의 신규한 제조 방법
KR101098553B1 (ko) *	2008-04-30	2011-12-26	주식회사 엘지생명과학	이오프로마이드의 신규한 제조방법
BRPI0915124B1 (pt)	2008-06-17	2018-02-27	F. Hoffmann - La Roche - Ag	"derivado de éster de ácido 1-(2-etil-butil)-ciclo- hexanocarboxílico, seus processos de preparação, e processo para preparação de s-[2-([[1-(2-etilbutil)- ciclo-hexil]-carbonil]amina)fenil]2- metilpropanotioato"
AU2009317450B2 (en) *	2008-11-18	2015-05-07	Bracco Imaging Spa	Process for the preparation of iodinated contrast agent
CN102725249B (zh)	2009-11-26	2014-12-10	好利安中国控股有限公司	碘克沙醇的制备和纯化
US9180137B2 (en)	2010-02-09	2015-11-10	Bone Support Ab	Preparation of bone cement compositions
IT1403988B1 (it) *	2010-07-15	2013-11-08	Bracco Imaging Spa	Processo per la preparazione di agenti di contrasto.
DK2958603T3 (en)	2013-02-20	2018-07-16	Bone Support Ab	IMPROVED CURE FOR HARDWARE BONE COMPENSATION
KR101520187B1 (ko)	2013-10-25	2015-05-13	주식회사 대웅제약	이오프로마이드의 중간체의 제조방법
CN106316878B (zh) *	2015-06-15	2018-01-19	重庆常捷医药有限公司	一种碘美普尔杂质的制备方法
EP3548461B1 (en)	2016-12-05	2021-02-03	Bracco Imaging SpA	Mechanochemical synthesis of radiographic agents intermediates
KR102128423B1 (ko) *	2018-09-17	2020-07-01	(주)유케이케미팜	조영제 이오메프롤의 제조방법
CN114478298A (zh) *	2020-11-12	2022-05-13	成都西岭源药业有限公司	一种造影剂碘佛醇的纯化方法
CN113387833A (zh) *	2021-05-25	2021-09-14	成都丽璟科技有限公司	一种低渗透性泛影酸衍生物造影剂及其制备方法
CN115872894A (zh) *	2022-11-15	2023-03-31	上海慧聚药业有限公司	非离子型造影剂的合成
CN116332787B (zh) *	2023-03-03	2023-10-27	安庆朗坤药业有限公司	一种造影剂中间体乙酰碘化物的制备方法

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CH608189A5 (no) *	1974-12-13	1978-12-29	Savac Ag
GB1548594A (en) *	1976-06-11	1979-07-18	Nyegaard & Co As	Triiodoisophthalic acid amides
CN1157367C (zh) *	1995-05-23	2004-07-14	伯拉考成像股份公司	制备二酰氯的方法

1997
- 1997-05-30 IT IT97MI001268A patent/IT1292037B1/it active IP Right Grant
1998
- 1998-05-19 AU AU80185/98A patent/AU729759B2/en not_active Ceased
- 1998-05-19 ES ES98928291T patent/ES2152747T3/es not_active Expired - Lifetime
- 1998-05-19 WO PCT/EP1998/002927 patent/WO1998054124A1/en not_active Application Discontinuation
- 1998-05-19 JP JP50018399A patent/JP3437584B2/ja not_active Expired - Lifetime
- 1998-05-19 KR KR1019997000722A patent/KR20000029649A/ko not_active Application Discontinuation
- 1998-05-19 EP EP98928291A patent/EP0915835B1/en not_active Expired - Lifetime
- 1998-05-19 CZ CZ99253A patent/CZ25399A3/cs unknown
- 1998-05-19 CN CN98800714A patent/CN1228079A/zh active Pending
- 1998-05-19 DK DK98928291T patent/DK0915835T3/da active
- 1998-05-19 AT AT98928291T patent/ATE198191T1/de not_active IP Right Cessation
- 1998-05-19 PT PT98928291T patent/PT915835E/pt unknown
- 1998-05-19 DE DE69800434T patent/DE69800434T2/de not_active Expired - Lifetime
- 1998-05-19 PL PL98331208A patent/PL331208A1/xx unknown
- 1998-05-19 CA CA002261656A patent/CA2261656A1/en not_active Abandoned
- 1998-05-28 US US09/084,922 patent/US5965772A/en not_active Expired - Lifetime
1999
- 1999-01-25 NO NO19990334A patent/NO323475B1/no not_active IP Right Cessation
2000
- 2000-12-21 GR GR20000402639T patent/GR3035123T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
WO1998054124A1 (en)	1998-12-03
JP2000505820A (ja)	2000-05-16
PT915835E (pt)	2001-03-30
DK0915835T3 (da)	2001-02-05
ATE198191T1 (de)	2001-01-15
IT1292037B1 (it)	1999-01-25
AU8018598A (en)	1998-12-30
NO323475B1 (no)	2007-05-21
CN1228079A (zh)	1999-09-08
CZ25399A3 (cs)	1999-07-14
CA2261656A1 (en)	1998-12-03
EP0915835B1 (en)	2000-12-20
KR20000029649A (ko)	2000-05-25
US5965772A (en)	1999-10-12
ITMI971268A1 (it)	1998-11-30
GR3035123T3 (en)	2001-03-30
DE69800434T2 (de)	2001-04-19
ES2152747T3 (es)	2001-02-01
PL331208A1 (en)	1999-07-05
DE69800434D1 (de)	2001-01-25
JP3437584B2 (ja)	2003-08-18
EP0915835A1 (en)	1999-05-19
ITMI971268A0 (no)	1997-05-30
NO990334L (no)	1999-03-26
AU729759B2 (en)	2001-02-08

Legal Events

Date	Code	Title	Description
2018-06-11	MK1K	Patent expired

Publication	Publication Date	Title
NO990334D0 (no)	1999-01-25	FremgangsmÕte ved fremstilling av 5-[acetyl(2,3-dihydroksypropyl)amino]-N,N'-bis(2,3-dihydroksypropyl)-2,4,6-triiod-1,3-benzendikarboksamid
AU731777B2 (en)	2001-04-05	Aniline derivative and process for producing the same
JP2007308503A (ja)	2007-11-29	ジカルボン酸二塩化物の製造方法
GB2163154A (en)	1986-02-19	Diamino tetrafluoroethoxy benzene derivatives and their use as couplers in hair dyeing composition
CA2430339A1 (en)	2002-06-06	A process for the preparation of iopamidol and the new intermediates therein
FR2928148A1 (fr)	2009-09-04	Procede de preparation de combretastatine
US5824821A (en)	1998-10-20	Process for the preparation of iodinated contrast agents and intermediates therefor
US5545754A (en)	1996-08-13	Process for the preparation of p-amino-phenols
NO853953L (no)	1986-04-10	R¯ntgenkontrastmidler.
KR860008135A (ko)	1986-11-12	아미노케톤 유도체의 제조방법
US3055928A (en)	1962-09-25	Esters of 2-carbamoylbenzenesulfonic acids
US4922019A (en)	1990-05-01	Derivatives of 2,2-bis-(3-aminophenyl)hexafluoropropane and process for the preparation of 2,2-bis-(3,4-diaminophenyl)hexafluoropropane
JPS6026154B2 (ja)	1985-06-21	塩基性オキサジン染料の製造法
AU767379B2 (en)	2003-11-06	Chemical processes
KR100524146B1 (ko)	2005-10-26	아이오디사놀의 신규 제조방법
KR100539067B1 (ko)	2005-12-26	Ｘ-선 조영제로서 아이오디사놀의 신규 제조방법
JPS58146527A (ja)	1983-09-01	ベンツアルデヒド類の製造法
KR20040087044A (ko)	2004-10-13	아이오디사놀 유도체의 제조방법
KR890008077A (ko)	1989-07-08	4,4'-비스[2-(4- 하이드록시페닐)헥사플루오로이소프로필]디페닐에테르를 기본으로 하는 플루오로-함유 화합물, 그의 제조방법 및 그의 용도
CA1137472A (en)	1982-12-14	2,3-alkylene bis(oxy)benzoic acids
Jadhav et al.	0	Hypervalent (III) Iodine Reagent Catalyzed Highly Efficient N-Formylation in Water with Oxone® as a Co-oxidant
GB951461A (en)	1964-03-04	Improvements in or relating to substituted 2-phenoxy-cyclopropylamines
CN117920215A (zh)	2024-04-26	氢氧化锆和氧化铜物理混合催化剂催化苯胺或其衍生物制备亚硝基苯或其衍生物的应用
JPH0413651A (ja)	1992-01-17	４―トリフルオロメチルアニリン誘導体及びその製造法
CN107400062A (zh)	2017-11-28	一种合成碘昔兰的新方法