NO983197L - Nye trisykliske forbindelser og medikamentsammensetninger inneholdende slike - Google Patents

Nye trisykliske forbindelser og medikamentsammensetninger inneholdende slike

Info

Publication number
NO983197L
NO983197L NO983197A NO983197A NO983197L NO 983197 L NO983197 L NO 983197L NO 983197 A NO983197 A NO 983197A NO 983197 A NO983197 A NO 983197A NO 983197 L NO983197 L NO 983197L
Authority
NO
Norway
Prior art keywords
represents hydrogen
amino
compositions containing
tricyclic compounds
drug compositions
Prior art date
Application number
NO983197A
Other languages
English (en)
Other versions
NO312159B1 (no
Inventor
Shiro Miyoshi
Kohei Ogawa
Original Assignee
Asahi Chemical Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Ind filed Critical Asahi Chemical Ind
Publication of NO983197L publication Critical patent/NO983197L/no
Publication of NO312159B1 publication Critical patent/NO312159B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/91Dibenzofurans; Hydrogenated dibenzofurans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C307/00Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C307/04Diamides of sulfuric acids
    • C07C307/10Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/08Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/88Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/76Dibenzothiophenes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO19983197A 1996-01-10 1998-07-10 Nye trisykliske forbindelser og medikamentsammensetninger inneholdende slike NO312159B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP257696 1996-01-10
PCT/JP1996/003689 WO1997025311A1 (fr) 1996-01-10 1996-12-18 Nouveaux composes tricycliques et compositions medicamenteuses contenant ces composes

Publications (2)

Publication Number Publication Date
NO983197L true NO983197L (no) 1998-09-10
NO312159B1 NO312159B1 (no) 2002-04-02

Family

ID=11533209

Family Applications (2)

Application Number Title Priority Date Filing Date
NO19983197A NO312159B1 (no) 1996-01-10 1998-07-10 Nye trisykliske forbindelser og medikamentsammensetninger inneholdende slike
NO20012876A NO20012876D0 (no) 1996-01-10 2001-06-11 Nye trisykliske forbindelser og medikamentsammensetninger inneholdende slike

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20012876A NO20012876D0 (no) 1996-01-10 2001-06-11 Nye trisykliske forbindelser og medikamentsammensetninger inneholdende slike

Country Status (14)

Country Link
US (4) US6037362A (no)
EP (1) EP0882707B1 (no)
JP (1) JP2000239255A (no)
KR (1) KR100395280B1 (no)
CN (2) CN1083831C (no)
AT (1) ATE251608T1 (no)
AU (1) AU715233B2 (no)
CA (1) CA2242351C (no)
DE (1) DE69630319T2 (no)
ES (1) ES2208772T3 (no)
HK (1) HK1017669A1 (no)
NO (2) NO312159B1 (no)
PT (1) PT882707E (no)
WO (1) WO1997025311A1 (no)

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US6040344A (en) * 1996-11-11 2000-03-21 Sepracor Inc. Formoterol process
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WO1999051564A1 (en) * 1998-04-06 1999-10-14 Fujisawa Pharmaceutical Co., Ltd. Propanolamine derivatives
US20030073644A1 (en) * 1998-11-11 2003-04-17 Smithkline Beecham P.L.C. Combinations comprising a beta-agonist and a further antidiabetic agent
AU766928B2 (en) * 1998-11-11 2003-10-23 Smithkline Beecham Plc Combinations comprising a beta-agonist and a further antidiabetic agent
KR20010080761A (ko) * 1998-12-15 2001-08-22 야마모토 카즈모토 신규한 복소환 화합물 및 이를 함유하는 의약 조성물
TW519537B (en) 1999-03-26 2003-02-01 Asahi Chemical Ind Process for the preparation of tricylic amino-alcohol derivatives
CA2365503A1 (en) * 1999-04-01 2000-10-12 Koki Matsubara Method for the preparation of tricyclic amino alcohol derivatives through azides
EP1195371A1 (en) * 1999-07-09 2002-04-10 Asahi Kasei Kabushiki Kaisha Process for the preparation of tricyclic amino alcohol derivatives
US6696573B1 (en) 1999-09-03 2004-02-24 Asahi Kasei Kabushiki Kaisha Processes for the preparation of tricyclic amino alcohol derivatives
US20030220329A1 (en) * 1999-09-17 2003-11-27 Duke University Method of improving beta-adrenergic receptor function
WO2001025198A1 (fr) * 1999-10-04 2001-04-12 Asahi Kasei Kabushiki Kaisha Amelioration de la solubilite de derives d'alcools amines tricycliques
WO2001044187A1 (fr) * 1999-12-16 2001-06-21 Asahi Kasei Kabushiki Kaisha Nouveaux composes tricycliques substitues
US20030018061A1 (en) * 2000-01-28 2003-01-23 Kohei Ogawa Novel remedies with the use of beta 3 agonist
AU2001252575A1 (en) * 2000-04-28 2001-11-12 Asahi Kasei Kabushiki Kaisha Novel tricyclic compounds
WO2001083453A1 (fr) * 2000-04-28 2001-11-08 Asahi Kasei Kabushiki Kaisha Nouveaux composes tricycliques substitues
AU5257401A (en) * 2000-04-28 2001-11-12 Asahi Chemical Ind Novel bicyclic compounds
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JPWO2002074306A1 (ja) * 2001-03-19 2004-07-08 旭化成ファーマ株式会社 脂肪肝治療薬
GB0121941D0 (en) * 2001-09-11 2001-10-31 Astrazeneca Ab Chemical compounds
KR100816527B1 (ko) * 2001-09-12 2008-04-10 한국화학연구원 페닐테트라졸 유도체로 치환된 β-아미노알코올 화합물
DE60228990D1 (de) 2001-10-25 2008-10-30 Asahi Kasei Pharma Corp Bicyclische verbindung
AU2003209527A1 (en) * 2002-02-27 2003-09-09 Pfizer Products Inc. Crystal forms of (r)-2-(2-(4-oxazol-4-yl-phenoxy)-ethylamino)-1-pyridin-3-yl-ethanol
US6864268B2 (en) 2002-02-27 2005-03-08 Pfizer Inc. β3 adrenergic receptor agonists
WO2003072547A1 (en) 2002-02-27 2003-09-04 Pfizer Products Inc. PROCESSES AND INTERMEDIATES USEFUL IN PREPARING β3-ADRENERGIC RECEPTOR AGONISTS
EP1424079A1 (en) * 2002-11-27 2004-06-02 Boehringer Ingelheim International GmbH Combination of a beta-3-receptor agonist and of a reuptake inhibitor of serotonin and/or norepinephrine
BRPI0407386A (pt) 2003-02-14 2006-02-07 Kissei Pharmaceutical Derivados de álcool de amino, composições farmacêuticas contendo os mesmos e uso destes
EP1679304A4 (en) * 2003-10-24 2006-11-15 Kissei Pharmaceutical AMINO ALCOHOL DERIVATIVE, MEDICAL COMPOSITION CONTAINING THEREOF AND ITS USE
US7718822B2 (en) 2007-08-28 2010-05-18 Sepracor Inc. Carbamate Stereoisomer
US8501994B2 (en) 2007-08-28 2013-08-06 Sunovion Pharmaceuticals Inc. Acetamide stereoisomer
CA2740772A1 (en) 2008-10-09 2010-04-15 Asahi Kasei Pharma Corporation Indazole compounds
AU2009301797B2 (en) * 2008-10-09 2012-03-01 Asahi Kasei Pharma Corporation Indazole derivative
US20100222404A1 (en) * 2008-11-04 2010-09-02 Asahi Kasei Pharma Corporation Indazole derivative dihydrochloride
CA2775464A1 (en) * 2009-09-30 2011-04-07 Asahi Kasei Pharma Corporation Indazole analog
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ES2394349B1 (es) 2012-08-29 2013-11-04 Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii Uso de agonistas selectivos de receptores beta-3 adrenérgicos para el tratamiento de hipertensión pulmonar
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Also Published As

Publication number Publication date
CN1083831C (zh) 2002-05-01
PT882707E (pt) 2004-02-27
ATE251608T1 (de) 2003-10-15
HK1017669A1 (en) 1999-11-26
DE69630319D1 (de) 2003-11-13
CA2242351A1 (en) 1997-07-17
KR19990077162A (ko) 1999-10-25
AU1170897A (en) 1997-08-01
ES2208772T3 (es) 2004-06-16
NO20012876D0 (no) 2001-06-11
AU715233B2 (en) 2000-01-20
US20030139475A1 (en) 2003-07-24
NO20012876L (no) 1998-09-10
DE69630319T2 (de) 2004-07-29
US6545053B1 (en) 2003-04-08
KR100395280B1 (ko) 2004-06-04
EP0882707B1 (en) 2003-10-08
JP2000239255A (ja) 2000-09-05
CN1295064A (zh) 2001-05-16
CA2242351C (en) 2003-03-11
EP0882707A1 (en) 1998-12-09
CN1209119A (zh) 1999-02-24
EP0882707A4 (en) 2001-04-11
US6187809B1 (en) 2001-02-13
NO312159B1 (no) 2002-04-02
US6037362A (en) 2000-03-14
WO1997025311A1 (fr) 1997-07-17

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Free format text: LAPSED IN JUNE 2003