NO965431D0 - Höy-affinitet melatoninreseptorer og anvendelser derav - Google Patents

Höy-affinitet melatoninreseptorer og anvendelser derav

Info

Publication number: NO965431D0
Authority: NO; Norway
Prior art keywords: receptor; melatonin; affinity; affinity melatonin; cdnas
Prior art date: 1994-06-17

Application number

NO965431A

Other languages

English (en)

Other versions

NO965431L (no

Inventor

Steven M Reppert

Takashi Ebisawa

Original Assignee

Gen Hospital Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-06-17

Filing date

1996-12-17

Publication date

1996-12-17

1996-12-17 Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp

1996-12-17 Publication of NO965431D0 publication Critical patent/NO965431D0/no

1997-02-14 Publication of NO965431L publication Critical patent/NO965431L/no

Links

102000001419 Melatonin receptor Human genes 0.000 title abstract 3
108050009605 Melatonin receptor Proteins 0.000 title abstract 3
102000005962 receptors Human genes 0.000 abstract 4
108020003175 receptors Proteins 0.000 abstract 4
YJPIGAIKUZMOQA-UHFFFAOYSA-N Melatonin Natural products COC1=CC=C2N(C(C)=O)C=C(CCN)C2=C1 YJPIGAIKUZMOQA-UHFFFAOYSA-N 0.000 abstract 3
DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical compound COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 abstract 3
229960003987 melatonin Drugs 0.000 abstract 3
108020004635 Complementary DNA Proteins 0.000 abstract 2
239000000556 agonist Substances 0.000 abstract 2
239000005557 antagonist Substances 0.000 abstract 2
239000003814 drug Substances 0.000 abstract 2
239000012634 fragment Substances 0.000 abstract 2
229920001184 polypeptide Polymers 0.000 abstract 2
102000004196 processed proteins & peptides Human genes 0.000 abstract 2
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
208000017164 Chronobiology disease Diseases 0.000 abstract 1
108020004414 DNA Proteins 0.000 abstract 1
241001465754 Metazoa Species 0.000 abstract 1
238000009395 breeding Methods 0.000 abstract 1
230000001488 breeding effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000000977 initiatory effect Effects 0.000 abstract 1
230000003993 interaction Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
230000001850 reproductive effect Effects 0.000 abstract 1
230000033764 rhythmic process Effects 0.000 abstract 1
238000012216 screening Methods 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Biochemistry (AREA)
Cell Biology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Toxicology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Peptides Or Proteins (AREA)
Indole Compounds (AREA)
Investigating Or Analysing Biological Materials (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO965431A 1994-06-17 1996-12-17 Höy-affinitet melatoninreseptorer og anvendelser derav NO965431L (no)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US26185794A	1994-06-17	1994-06-17
US31988794A	1994-10-07	1994-10-07
US08/466,103 US5856124A (en)	1994-06-17	1995-06-06	DNA encoding high-affinity melatonin receptors
PCT/US1995/007360 WO1995035320A1 (en)	1994-06-17	1995-06-07	High-affinity melatonin receptors and uses thereof

Publications (2)

Publication Number	Publication Date
NO965431D0 true NO965431D0 (no)	1996-12-17
NO965431L NO965431L (no)	1997-02-14

Family

ID=27401451

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO965431A NO965431L (no)	1994-06-17	1996-12-17	Höy-affinitet melatoninreseptorer og anvendelser derav

Country Status (13)

Country	Link
US (1)	US5856124A (no)
EP (1)	EP0769024B1 (no)
JP (1)	JP2002515003A (no)
AT (1)	ATE309348T1 (no)
AU (1)	AU689905B2 (no)
CA (1)	CA2193205A1 (no)
DE (1)	DE69534597T2 (no)
DK (1)	DK0769024T3 (no)
ES (1)	ES2252743T3 (no)
FI (1)	FI965043A (no)
IL (1)	IL114200A (no)
NO (1)	NO965431L (no)
WO (1)	WO1995035320A1 (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7081349B1 (en)	1994-06-17	2006-07-25	The General Hospital Corporation	High-affinity melatonin receptor and uses thereof
FR2737220B1 (fr) *	1995-07-24	1997-09-26	Adir	Sequences nucleiques codant pour des recepteurs de la melatonine et leurs applications
US6034239A (en) *	1996-03-08	2000-03-07	Takeda Chemical Industries, Ltd.	Tricyclic compounds, their production and use
WO1998003549A1 (en) *	1996-07-18	1998-01-29	The General Hospital Corporation	MELATONIN 1a RECEPTOR GENE REGULATORY REGIONS AND USES THEREOF
US5939264A (en) *	1996-07-19	1999-08-17	Iowa State University Research Foundation, Inc.	Genes and genetic markers for improved reproductive traits in animals
JPH119282A (ja) *	1997-06-19	1999-01-19	Nippon Chem Res Kk	メラトニン受容体発現細胞とその用途
WO2001007654A1 (en)	1999-07-22	2001-02-01	The General Hospital Corporation	Method for identifying compounds which modulate circadian rhythm
ATE293628T1 (de)	1999-08-20	2005-05-15	Takeda Pharmaceutical	Dihydrobenzofuranderivate, verfahren zu ihrer herstellung und mittel
DE10014690A1 (de) *	2000-03-24	2001-10-18	Franz Wolfgang M	Verfahren zur Isolierung in vito differenzierter Körperzellen
FR2835847B1 (fr) *	2002-02-08	2004-12-03	Servier Lab	Sequence d'acides nucleiques codant un nouveau recepteur de la melatonine et utilisations
CA2373854A1 (en) *	2002-02-28	2003-08-28	Alain Moreau	Methods of diagnosing and counteracting adolescent idiopathic scoliosis
AU2003228531A1 (en) *	2002-04-15	2003-11-03	The Regents Of The University Of California	Screening and therapeutic methods for treating circadian rhythm disorders
US20050137247A1 (en) *	2003-12-22	2005-06-23	The Brigham And Women's Hospital, Inc.	Methods and compositions for treatment of hypertension
WO2005078455A1 (en) *	2004-02-18	2005-08-25	Bayer Healthcare Ag	Diagnostics and therapeutics for diseases associated with human melatonin receptor type 1a (mtnr1a)
WO2005078444A1 (en) *	2004-02-18	2005-08-25	Bayer Healthcare Ag	Diagnostics and therapeutics for diseases associated with human melatonin receptor type 1b (mtnr1b)
KR101394594B1 (ko) *	2007-02-15	2014-05-14	슈 생-쥐스땡	골 재흡수 및 골 형성 간의 불균형을 보정하는 방법 및 이를 위한 키트 및 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL79264A0 (en) *	1986-06-27	1986-09-30	Univ Ramot	Tryptamine derivatives,pharmaceutical compositions containing them and their use in an assay for melatonin receptors
FR2658818B1 (fr)	1990-02-27	1993-12-31	Adir Cie	Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
JPH06510363A (ja) *	1990-10-29	1994-11-17	ディカルブ　プラント　ジェネティクス	磁気性粒子を使用する生物学的材料の単離
FR2674524B1 (fr)	1991-03-25	1993-05-21	Adir	Nouveaux amides alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2680366B1 (fr)	1991-08-13	1995-01-20	Adir	Nouveaux derives d'arylethylamines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
FR2696453B1 (fr)	1992-10-02	1994-12-23	Adir	Nouveaux arylalkyl(thio)amides, leur procédé de préparation, et les compositions pharmaceutiques qui les contiennent.

1995
- 1995-06-06 US US08/466,103 patent/US5856124A/en not_active Expired - Fee Related
- 1995-06-07 DK DK95922284T patent/DK0769024T3/da active
- 1995-06-07 ES ES95922284T patent/ES2252743T3/es not_active Expired - Lifetime
- 1995-06-07 CA CA002193205A patent/CA2193205A1/en not_active Abandoned
- 1995-06-07 EP EP95922284A patent/EP0769024B1/en not_active Expired - Lifetime
- 1995-06-07 WO PCT/US1995/007360 patent/WO1995035320A1/en active IP Right Grant
- 1995-06-07 JP JP50235596A patent/JP2002515003A/ja not_active Ceased
- 1995-06-07 DE DE69534597T patent/DE69534597T2/de not_active Expired - Fee Related
- 1995-06-07 AU AU27023/95A patent/AU689905B2/en not_active Ceased
- 1995-06-07 AT AT95922284T patent/ATE309348T1/de not_active IP Right Cessation
- 1995-06-18 IL IL11420095A patent/IL114200A/en not_active IP Right Cessation
1996
- 1996-12-16 FI FI965043A patent/FI965043A/fi unknown
- 1996-12-17 NO NO965431A patent/NO965431L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU689905B2 (en)	1998-04-09
FI965043A (fi)	1997-02-13
EP0769024A4 (en)	1999-06-30
DE69534597T2 (de)	2006-08-10
AU2702395A (en)	1996-01-15
EP0769024A1 (en)	1997-04-23
IL114200A0 (en)	1995-11-27
ES2252743T3 (es)	2006-05-16
JP2002515003A (ja)	2002-05-21
DE69534597D1 (de)	2005-12-15
CA2193205A1 (en)	1995-12-28
WO1995035320A1 (en)	1995-12-28
NO965431L (no)	1997-02-14
EP0769024B1 (en)	2005-11-09
DK0769024T3 (da)	2006-03-27
ATE309348T1 (de)	2005-11-15
US5856124A (en)	1999-01-05
FI965043A0 (fi)	1996-12-16
IL114200A (en)	2004-06-20

Legal Events

Date	Code	Title	Description
2005-10-17	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO965431L (no)	1997-02-14	Höy-affinitet melatoninreseptorer og anvendelser derav
DE69837996D1 (de)	2007-08-09	Tumornekrosefaktor-rezeptoren 6 alpha& 6 beta
EP1009804A4 (en)	2001-05-16	NUCLEIC ACID SEQUENCES ENCODING THE CAPSAICIN RECEPTOR AND POLYPEPTIDES SIMILAR TO THE CAPSAICIN RECEPTOR AND THEIR USE
DE69333027D1 (de)	2003-07-10	Fusionsprotein , das zwei rezeptoren des tumornekrose-faktors enthält
DE69841140D1 (de)	2009-10-22	Interleukin-17 rezeptor-ähnliches protein
EA200401329A1 (ru)	2005-10-27	Способ лечения заболеваний, связанных с tweak
NL300008I2 (nl)	2000-12-01	Tumornecrosis factor-alfa en -bet-receptors.
DK0669979T3 (da)	2006-03-06	C-C CKR-1, kemokinreceptor
FI960727A0 (fi)	1996-02-16	Neurokiniiniantagonisteina käyttökelpoiset heterosyklit
DK1482042T3 (da)	2009-06-15	Aktive og inaktive CC-kemokinreceptorer og nukleinsyremolekyler der koder for receptoren
DK0751992T3 (da)	2006-03-06	Karendotelvækstfaktor 2
EP0577605A4 (no)	1994-04-13
DE69434926D1 (de)	2007-04-05	Menschlicher gewebsinhibitor von metalloproteinase-4
MXPA03003902A (es)	2004-04-02	Polipeptidos de proquineticina, composiciones relacionadas y metodos.
ATE342976T1 (de)	2006-11-15	Cytokinrezeptor-kette
DE69432595D1 (de)	2003-06-05	Antagonisten des angiotensin ii-rezeptors zur behandlung von chronischen entzündlichen erkrankungen
TR199700956T1 (xx)	1998-02-21	Indazolkarboksamidler.
DE69033990D1 (de)	2002-08-29	Glykoprotein-Hormonrezeptor-Moleküle
NO915084L (no)	1992-06-29	Fremgangsmaate ved fremstilling av human interleukin-5 receptor
DK0639225T3 (da)	2003-02-17	Nye polypeptider og peptider, nucleinsyrer, der koder for dem, og deres anvendelse i området tumorterapi, inflammation eller immunologi
ATE325816T1 (de)	2006-06-15	Regulatorische regionen des gens für den melatonin 1a rezeptor und deren verwendungen