NO953638L - Gas-generating contrast agents - Google Patents

Gas-generating contrast agents

Info

Publication number
NO953638L
NO953638L NO953638A NO953638A NO953638L NO 953638 L NO953638 L NO 953638L NO 953638 A NO953638 A NO 953638A NO 953638 A NO953638 A NO 953638A NO 953638 L NO953638 L NO 953638L
Authority
NO
Norway
Prior art keywords
contrast agents
gas
generating contrast
generating
formulation
Prior art date
Application number
NO953638A
Other languages
Norwegian (no)
Other versions
NO953638D0 (en
Inventor
Arne Aabye
Arne Berg
Harald Dugstad
Kari Dyvik
Per A Foss
Jo Klaveness
Jonny Oestensen
Paal Rongved
Per Strande
Helge Tolleshaug
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of NO953638L publication Critical patent/NO953638L/en
Publication of NO953638D0 publication Critical patent/NO953638D0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)

Abstract

Mikropartikulære materialer som kjemisk kan danne gass etter formulering med en passende bærervæske, f.eks. vann for injeksjon, og/eller etter administrering f.eks. som resultat av kontakt med blod eller andre kroppsvæsker, kan brukes som kontrastmidler i diagnostisk avbilding, spesielt ultralyd og magnetisk resonansavbilding.Microparticulate materials which can chemically form gas after formulation with a suitable carrier liquid, e.g. water for injection, and / or after administration e.g. as a result of contact with blood or other bodily fluids, can be used as contrast agents in diagnostic imaging, especially ultrasound and magnetic resonance imaging.

NO953638A 1993-03-16 1995-09-15 Gas-generating contrast agents NO953638D0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939305351A GB9305351D0 (en) 1993-03-16 1993-03-16 Improvements in or relating to contrast agents
PCT/GB1994/000522 WO1994021302A1 (en) 1993-03-16 1994-03-16 Improvements in or relating to contrast agents

Publications (2)

Publication Number Publication Date
NO953638L true NO953638L (en) 1995-09-15
NO953638D0 NO953638D0 (en) 1995-09-15

Family

ID=10732118

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953638A NO953638D0 (en) 1993-03-16 1995-09-15 Gas-generating contrast agents

Country Status (15)

Country Link
EP (1) EP0689462A1 (en)
JP (1) JPH08507781A (en)
KR (1) KR960700760A (en)
CN (1) CN1121314A (en)
AU (1) AU695529B2 (en)
BR (1) BR9406199A (en)
CA (1) CA2158359A1 (en)
CZ (1) CZ237195A3 (en)
FI (1) FI954326A (en)
GB (1) GB9305351D0 (en)
HU (1) HUT72984A (en)
NO (1) NO953638D0 (en)
PL (1) PL310657A1 (en)
SK (1) SK113795A3 (en)
WO (1) WO1994021302A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9106673D0 (en) * 1991-03-28 1991-05-15 Hafslund Nycomed As Improvements in or relating to contrast agents
US5409688A (en) * 1991-09-17 1995-04-25 Sonus Pharmaceuticals, Inc. Gaseous ultrasound contrast media
US5333613A (en) * 1993-03-23 1994-08-02 Delineate Microparticles as ultrasonic contrast media
US5897851A (en) * 1995-06-07 1999-04-27 Sonus Pharmaceuticals, Inc. Nucleation and activation of a liquid-in-liquid emulsion for use in ultrasound imaging
GB9511488D0 (en) * 1995-06-07 1995-08-02 Nycomed Imaging As Improvements in or relating to contrast agents
GB9622711D0 (en) 1996-10-31 1997-01-08 British Tech Group Instrument having enhanced ultrasound visibility
US6278893B1 (en) * 1998-01-05 2001-08-21 Nycomed Imaging As Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
US20070110674A1 (en) * 2005-07-29 2007-05-17 Yuhong Xu Sono-active liposomes and lipid particles and use thereof as contrast agents and active-agent delivery systems
CN113289034A (en) 2014-12-31 2021-08-24 蓝瑟斯医学影像公司 Lipid-encapsulated gas microsphere compositions and related methods
IL262647B2 (en) 2016-05-04 2023-03-01 Lantheus Medical Imaging Inc Methods and devices for preparation of ultrasound contrast agents
US9789210B1 (en) 2016-07-06 2017-10-17 Lantheus Medical Imaging, Inc. Methods for making ultrasound contrast agents
GB201821049D0 (en) * 2018-12-21 2019-02-06 Ge Healthcare As Ultrasound contrast agent and methods for use therof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4900540A (en) * 1983-06-20 1990-02-13 Trustees Of The University Of Massachusetts Lipisomes containing gas for ultrasound detection
US4684479A (en) * 1985-08-14 1987-08-04 Arrigo Joseph S D Surfactant mixtures, stable gas-in-liquid emulsions, and methods for the production of such emulsions from said mixtures
JPH0678247B2 (en) * 1988-10-04 1994-10-05 大塚製薬株式会社 Iron-containing preparation for NMR contrast
US5147631A (en) * 1991-04-30 1992-09-15 Du Pont Merck Pharmaceutical Company Porous inorganic ultrasound contrast agents
JP3650393B2 (en) * 1992-03-06 2005-05-18 アメルシャム ヘルス アクスイェ セルスカプ Improvements in or on contrast media

Also Published As

Publication number Publication date
GB9305351D0 (en) 1993-05-05
AU6215394A (en) 1994-10-11
EP0689462A1 (en) 1996-01-03
FI954326A0 (en) 1995-09-14
CN1121314A (en) 1996-04-24
HUT72984A (en) 1996-06-28
BR9406199A (en) 1995-12-12
JPH08507781A (en) 1996-08-20
PL310657A1 (en) 1995-12-27
FI954326A (en) 1995-10-11
KR960700760A (en) 1996-02-24
WO1994021302A1 (en) 1994-09-29
HU9502693D0 (en) 1995-11-28
NO953638D0 (en) 1995-09-15
AU695529B2 (en) 1998-08-13
CZ237195A3 (en) 1996-05-15
CA2158359A1 (en) 1994-09-29
SK113795A3 (en) 1997-02-05

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