NO953637L - Emulgert gass som ultralyd-kontrastmiddel - Google Patents
Emulgert gass som ultralyd-kontrastmiddelInfo
- Publication number
- NO953637L NO953637L NO953637A NO953637A NO953637L NO 953637 L NO953637 L NO 953637L NO 953637 A NO953637 A NO 953637A NO 953637 A NO953637 A NO 953637A NO 953637 L NO953637 L NO 953637L
- Authority
- NO
- Norway
- Prior art keywords
- gas
- oil
- contrast agent
- ultrasonic contrast
- emulsified gas
- Prior art date
Links
- 239000002961 echo contrast media Substances 0.000 title abstract 2
- 239000000839 emulsion Substances 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/226—Solutes, emulsions, suspensions, dispersions, semi-solid forms, e.g. hydrogels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acoustics & Sound (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Dispersion Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Application Of Or Painting With Fluid Materials (AREA)
- Coating Apparatus (AREA)
Abstract
Olje-i-vann emulsjoner der oljefasen omfatter kondensert eller oppløst olje-løselig gass/væske eller gassforløper er nyttige som ultralyd-kontrastmidler. Slike produkter inneholder ubetydelige mengder av frie gassbobler eller mikrobobler under lagring, og framviser god lagringsstabilitet, men kan utformes slik at de fremmer rask dannelse av mikrobobler umiddelbart før eller ved administrering.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939305349A GB9305349D0 (en) | 1993-03-16 | 1993-03-16 | Improvements in or relating to contrast agents |
PCT/GB1994/000521 WO1994021301A1 (en) | 1993-03-16 | 1994-03-16 | Improvements in or relating to contrast agents |
Publications (2)
Publication Number | Publication Date |
---|---|
NO953637L true NO953637L (no) | 1995-09-15 |
NO953637D0 NO953637D0 (no) | 1995-09-15 |
Family
ID=10732116
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO953637A NO953637D0 (no) | 1993-03-16 | 1995-09-15 | Emulgert gass som ultralyd-kontrastmiddel |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP0689461B1 (no) |
JP (1) | JP3787639B2 (no) |
KR (1) | KR960700759A (no) |
CN (1) | CN1066963C (no) |
AT (1) | ATE194292T1 (no) |
AU (1) | AU696091B2 (no) |
BG (2) | BG62084B1 (no) |
BR (1) | BR9406228A (no) |
CA (1) | CA2158365A1 (no) |
CZ (1) | CZ237095A3 (no) |
DE (1) | DE69425136T2 (no) |
ES (1) | ES2147784T3 (no) |
FI (1) | FI954325A (no) |
GB (1) | GB9305349D0 (no) |
HK (1) | HK1004981A1 (no) |
HU (1) | HUT72982A (no) |
NO (1) | NO953637D0 (no) |
PL (1) | PL175128B1 (no) |
RU (1) | RU2128520C1 (no) |
SK (1) | SK113895A3 (no) |
WO (1) | WO1994021301A1 (no) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5874062A (en) * | 1991-04-05 | 1999-02-23 | Imarx Pharmaceutical Corp. | Methods of computed tomography using perfluorocarbon gaseous filled microspheres as contrast agents |
US5409688A (en) * | 1991-09-17 | 1995-04-25 | Sonus Pharmaceuticals, Inc. | Gaseous ultrasound contrast media |
AU5457394A (en) * | 1992-11-02 | 1994-05-24 | Drexel University | Surfactant-stabilized microbubble mixtures, process for preparing and methods of using the same |
US5716597A (en) * | 1993-06-04 | 1998-02-10 | Molecular Biosystems, Inc. | Emulsions as contrast agents and method of use |
US5736121A (en) * | 1994-05-23 | 1998-04-07 | Imarx Pharmaceutical Corp. | Stabilized homogenous suspensions as computed tomography contrast agents |
US5897851A (en) * | 1995-06-07 | 1999-04-27 | Sonus Pharmaceuticals, Inc. | Nucleation and activation of a liquid-in-liquid emulsion for use in ultrasound imaging |
US5804162A (en) | 1995-06-07 | 1998-09-08 | Alliance Pharmaceutical Corp. | Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients |
US5834519A (en) * | 1996-10-11 | 1998-11-10 | Wayne State University | Stabilized gas-supersaturated emulsions and suspensions |
US6548047B1 (en) * | 1997-09-15 | 2003-04-15 | Bristol-Myers Squibb Medical Imaging, Inc. | Thermal preactivation of gaseous precursor filled compositions |
US20010003580A1 (en) | 1998-01-14 | 2001-06-14 | Poh K. Hui | Preparation of a lipid blend and a phospholipid suspension containing the lipid blend |
GB9808581D0 (en) * | 1998-04-22 | 1998-06-24 | Nycomed Imaging As | Improvements in or relating to contrast agents |
US6514209B1 (en) | 1999-06-07 | 2003-02-04 | Drexel University | Method of enhancing ultrasonic techniques via measurement of ultraharmonic signals |
AU2002223652A1 (en) * | 2000-10-24 | 2002-05-06 | C.C.H. S.A. | Endoscopic vascular visualisation, diagnostic and/or surgical procedure |
US8323620B2 (en) * | 2004-10-22 | 2012-12-04 | Hitachi Medical Corporation | Ultrasound contrast agent |
WO2007137236A2 (en) | 2006-05-19 | 2007-11-29 | Drexel University | Drug loaded contrast agents: combining diagnosis and therapy |
JP4800862B2 (ja) * | 2006-06-21 | 2011-10-26 | 株式会社日立製作所 | ファントム |
JP5124185B2 (ja) * | 2007-07-02 | 2013-01-23 | 株式会社日立製作所 | 診断又は治療用薬剤の調製方法及び装置 |
WO2013167654A1 (en) | 2012-05-09 | 2013-11-14 | Sinvent As | Ultrasound contact fluid |
IL252705B2 (en) | 2014-12-31 | 2023-03-01 | Lantheus Medical Imaging Inc | Fat-wrapped gas microsphere preparations and related methods |
AU2017260532A1 (en) | 2016-05-04 | 2018-11-22 | Lantheus Medical Imaging, Inc. | Methods and devices for preparation of ultrasound contrast agents |
US9789210B1 (en) | 2016-07-06 | 2017-10-17 | Lantheus Medical Imaging, Inc. | Methods for making ultrasound contrast agents |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4900540A (en) * | 1983-06-20 | 1990-02-13 | Trustees Of The University Of Massachusetts | Lipisomes containing gas for ultrasound detection |
US4684479A (en) * | 1985-08-14 | 1987-08-04 | Arrigo Joseph S D | Surfactant mixtures, stable gas-in-liquid emulsions, and methods for the production of such emulsions from said mixtures |
EP0245019A3 (en) * | 1986-04-30 | 1989-05-10 | Michael A. Davis | Low density contrast medium for diagnosis of pathologic conditions |
DE58908194D1 (de) * | 1988-02-05 | 1994-09-22 | Schering Ag | Ultraschallkontrastmittel, verfahren zu deren herstellung und deren verwendung als diagnostika und therapeutika. |
US5088499A (en) * | 1989-12-22 | 1992-02-18 | Unger Evan C | Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same |
JP3231768B2 (ja) * | 1991-09-17 | 2001-11-26 | ソーナス ファーマシューティカルス,インコーポレイテッド | 気体状超音波造影剤及び超音波造影剤として使用する気体の選定方法 |
IL104084A (en) * | 1992-01-24 | 1996-09-12 | Bracco Int Bv | Sustainable aqueous suspensions of pressure-resistant and gas-filled blisters, their preparation, and contrast agents containing them |
-
1993
- 1993-03-16 GB GB939305349A patent/GB9305349D0/en active Pending
-
1994
- 1994-03-16 ES ES94909226T patent/ES2147784T3/es not_active Expired - Lifetime
- 1994-03-16 PL PL94310656A patent/PL175128B1/pl unknown
- 1994-03-16 WO PCT/GB1994/000521 patent/WO1994021301A1/en not_active Application Discontinuation
- 1994-03-16 RU RU95121645A patent/RU2128520C1/ru active
- 1994-03-16 KR KR1019950703923A patent/KR960700759A/ko not_active Application Discontinuation
- 1994-03-16 DE DE69425136T patent/DE69425136T2/de not_active Expired - Fee Related
- 1994-03-16 AU AU62152/94A patent/AU696091B2/en not_active Ceased
- 1994-03-16 CA CA002158365A patent/CA2158365A1/en not_active Abandoned
- 1994-03-16 JP JP52077594A patent/JP3787639B2/ja not_active Expired - Fee Related
- 1994-03-16 BR BR9406228A patent/BR9406228A/pt not_active Application Discontinuation
- 1994-03-16 SK SK1138-95A patent/SK113895A3/sk unknown
- 1994-03-16 AT AT94909226T patent/ATE194292T1/de active
- 1994-03-16 CZ CZ952370A patent/CZ237095A3/cs unknown
- 1994-03-16 CN CN94191801A patent/CN1066963C/zh not_active Expired - Fee Related
- 1994-03-16 EP EP94909226A patent/EP0689461B1/en not_active Expired - Lifetime
- 1994-03-16 HU HU9502694A patent/HUT72982A/hu unknown
-
1995
- 1995-09-12 BG BG99998A patent/BG62084B1/bg unknown
- 1995-09-12 BG BG100272A patent/BG100272A/xx unknown
- 1995-09-14 FI FI954325A patent/FI954325A/fi unknown
- 1995-09-15 NO NO953637A patent/NO953637D0/no not_active Application Discontinuation
-
1998
- 1998-05-13 HK HK98104117A patent/HK1004981A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69425136T2 (de) | 2001-03-22 |
FI954325A (fi) | 1995-10-11 |
PL175128B1 (pl) | 1998-11-30 |
BG62084B1 (bg) | 1999-02-26 |
EP0689461A1 (en) | 1996-01-03 |
HU9502694D0 (en) | 1995-11-28 |
ATE194292T1 (de) | 2000-07-15 |
CZ237095A3 (en) | 1996-03-13 |
KR960700759A (ko) | 1996-02-24 |
CN1121315A (zh) | 1996-04-24 |
NO953637D0 (no) | 1995-09-15 |
SK113895A3 (en) | 1997-02-05 |
CA2158365A1 (en) | 1994-09-29 |
WO1994021301A1 (en) | 1994-09-29 |
PL310656A1 (en) | 1995-12-27 |
AU696091B2 (en) | 1998-09-03 |
HUT72982A (en) | 1996-06-28 |
AU6215294A (en) | 1994-10-11 |
BG100272A (en) | 1996-05-31 |
HK1004981A1 (en) | 1998-12-18 |
GB9305349D0 (en) | 1993-05-05 |
JP3787639B2 (ja) | 2006-06-21 |
RU2128520C1 (ru) | 1999-04-10 |
CN1066963C (zh) | 2001-06-13 |
FI954325A0 (fi) | 1995-09-14 |
BR9406228A (pt) | 1995-12-12 |
EP0689461B1 (en) | 2000-07-05 |
ES2147784T3 (es) | 2000-10-01 |
JPH08509706A (ja) | 1996-10-15 |
DE69425136D1 (de) | 2000-08-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |