NO940805D0 - O-heteroaryl, O-alkylheteroaryl, O-alkenylheteroaryl og O-alkynylheteroarylmakrolider - Google Patents

O-heteroaryl, O-alkylheteroaryl, O-alkenylheteroaryl og O-alkynylheteroarylmakrolider

Info

Publication number
NO940805D0
NO940805D0 NO940805A NO940805A NO940805D0 NO 940805 D0 NO940805 D0 NO 940805D0 NO 940805 A NO940805 A NO 940805A NO 940805 A NO940805 A NO 940805A NO 940805 D0 NO940805 D0 NO 940805D0
Authority
NO
Norway
Prior art keywords
heteroaryl
macrolides
alkynyl
alkenyl
alkyl
Prior art date
Application number
NO940805A
Other languages
English (en)
Other versions
NO940805L (no
Inventor
Peter J Sinclair
Frederick Wong
Joung Goulet
Mark Goulet
Williams H Parsons
Matthew J Wyvratt
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NO940805D0 publication Critical patent/NO940805D0/no
Publication of NO940805L publication Critical patent/NO940805L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measurement Of Force In General (AREA)
  • Steroid Compounds (AREA)
NO940805A 1991-09-09 1994-03-08 O-heteroaryl, O-alkylheteroaryl, O-alkenylheteroaryl og O-alkynylheteroarylmakrolider NO940805L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75694691A 1991-09-09 1991-09-09
US07/921,851 US5252732A (en) 1991-09-09 1992-08-05 D-heteroaryl, O-alkylheteroaryl, O-alkenylheteroaryl and O-alkynylheteroarylmacrolides having immunosuppressive activity
PCT/US1992/007508 WO1993005058A1 (en) 1991-09-09 1992-09-02 O-heteroaryl, o-alkylheteroaryl, o-alkenylheteroaryl and o-alkynylheteroarylmacrolides

Publications (2)

Publication Number Publication Date
NO940805D0 true NO940805D0 (no) 1994-03-08
NO940805L NO940805L (no) 1994-05-06

Family

ID=27116312

Family Applications (1)

Application Number Title Priority Date Filing Date
NO940805A NO940805L (no) 1991-09-09 1994-03-08 O-heteroaryl, O-alkylheteroaryl, O-alkenylheteroaryl og O-alkynylheteroarylmakrolider

Country Status (21)

Country Link
US (2) US5252732A (no)
EP (1) EP0532088B1 (no)
JP (1) JPH0813819B2 (no)
KR (1) KR930006030A (no)
CN (1) CN1073443A (no)
AT (1) ATE145915T1 (no)
AU (1) AU647665B2 (no)
BG (1) BG98639A (no)
CA (1) CA2077331A1 (no)
CZ (1) CZ53194A3 (no)
DE (1) DE69215615T2 (no)
FI (1) FI941085A (no)
HU (1) HUT66855A (no)
IL (1) IL103009A0 (no)
MX (1) MX9205137A (no)
NO (1) NO940805L (no)
NZ (1) NZ244153A (no)
RO (1) RO114331B1 (no)
SK (1) SK26094A3 (no)
WO (1) WO1993005058A1 (no)
YU (1) YU89792A (no)

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US5693648A (en) * 1994-09-30 1997-12-02 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynyl-macrolides having immunosuppressive activity
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EP1554572B1 (en) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
PL216224B1 (pl) * 2002-02-01 2014-03-31 Ariad Pharmaceuticals Pochodne rapamycyny zawierające fosfor, kompozycja je zawierająca oraz ich zastosowanie
JP2006516548A (ja) 2002-12-30 2006-07-06 アンジオテック インターナショナル アクツィエン ゲゼルシャフト 迅速ゲル化ポリマー組成物からの薬物送達法
CA2552305A1 (en) * 2003-12-30 2005-07-14 Astellas Pharma Inc. Use of macrolides for treating or preventing airflow obstruction
EP1768662A2 (en) 2004-06-24 2007-04-04 Novartis Vaccines and Diagnostics, Inc. Small molecule immunopotentiators and assays for their detection
CA2580286A1 (en) * 2004-09-16 2006-03-23 Bayer Healthcare Ag Dermally applicable formulations for treating skin diseases in animals
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WO2008036682A2 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
AU2007319825B2 (en) * 2006-11-14 2014-01-23 Ariad Pharmaceuticals, Inc. Oral formulations
US8921642B2 (en) * 2008-01-11 2014-12-30 Massachusetts Eye And Ear Infirmary Conditional-stop dimerizable caspase transgenic animals
KR101741629B1 (ko) 2009-05-06 2017-05-31 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
US8409807B2 (en) 2010-10-22 2013-04-02 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
US8563298B2 (en) 2010-10-22 2013-10-22 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
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EP2839038B1 (en) 2012-04-20 2019-01-16 T2 Biosystems, Inc. Compositions and methods for detection of candida species
US9593356B2 (en) 2013-06-11 2017-03-14 Takara Bio Usa, Inc. Protein enriched microvesicles and methods of making and using the same
US10143682B2 (en) 2014-10-28 2018-12-04 Koushi Yamaguchi Medicine for improving state of pregnancy, and use thereof
US11519016B2 (en) 2016-01-21 2022-12-06 T2 Biosystems, Inc. NMR methods and systems for the rapid detection of bacteria
CN106074367A (zh) * 2016-07-20 2016-11-09 中山大学中山眼科中心 含fk506类化合物/fkbp蛋白二聚体的药物组合物及其制备方法
JP7465806B2 (ja) 2018-08-10 2024-04-11 晃史 山口 母体と胎児との関係における液性免疫関連疾患の治療薬
CN109467579B (zh) * 2018-11-01 2021-10-15 海南大学 一种具有免疫抑制活性的pks i型聚酮类化合物及其制备方法和应用
AU2019401108A1 (en) 2018-12-18 2021-07-01 Koushi Yamaguchi Agent for improving infertility, recurrent miscarriage, and state of pregnancy

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Also Published As

Publication number Publication date
BG98639A (bg) 1995-03-31
EP0532088A1 (en) 1993-03-17
CN1073443A (zh) 1993-06-23
ATE145915T1 (de) 1996-12-15
NO940805L (no) 1994-05-06
NZ244153A (en) 1995-04-27
DE69215615T2 (de) 1997-06-26
US5252732A (en) 1993-10-12
EP0532088B1 (en) 1996-12-04
FI941085A (fi) 1994-05-03
CZ53194A3 (en) 1994-08-17
HU9400686D0 (en) 1994-06-28
YU89792A (sh) 1996-01-08
US5349061A (en) 1994-09-20
AU2282992A (en) 1993-03-11
HUT66855A (en) 1995-01-30
SK26094A3 (en) 1994-08-10
WO1993005058A1 (en) 1993-03-18
AU647665B2 (en) 1994-03-24
JPH0813819B2 (ja) 1996-02-14
FI941085A0 (fi) 1994-03-08
DE69215615D1 (de) 1997-01-16
RO114331B1 (ro) 1999-03-30
MX9205137A (es) 1993-04-01
JPH06116274A (ja) 1994-04-26
CA2077331A1 (en) 1993-03-10
KR930006030A (ko) 1993-04-20
IL103009A0 (en) 1993-02-21

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