NO940710L - Nye Esculetin-derivater og farmasöytisk blanding - Google Patents

Nye Esculetin-derivater og farmasöytisk blanding

Info

Publication number
NO940710L
NO940710L NO940710A NO940710A NO940710L NO 940710 L NO940710 L NO 940710L NO 940710 A NO940710 A NO 940710A NO 940710 A NO940710 A NO 940710A NO 940710 L NO940710 L NO 940710L
Authority
NO
Norway
Prior art keywords
hydrogen atom
new
group
independently
general formula
Prior art date
Application number
NO940710A
Other languages
English (en)
Other versions
NO940710D0 (no
Inventor
Koju Watanbe
Koichi Niimura
Kiyonori Umekawa
Original Assignee
Kureha Chemical Ind Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kureha Chemical Ind Co Ltd filed Critical Kureha Chemical Ind Co Ltd
Publication of NO940710D0 publication Critical patent/NO940710D0/no
Publication of NO940710L publication Critical patent/NO940710L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Farmasøytisk blanding som inneholder en forbindelse med den generelle formel (I): R2O d) hvori R1 og R2 uavhengig av hverandre, er et hydrogenatom, en mettet eller umettet alifatisk acylgruppe med fra 2 til 25 karbonatomer eller en benzoylgruppe, og R3 er et hydrogenatom eller en alkylgruppe, foruten et farmasøytisk akseptabelt fortynningsmiddel. Videre er det beskrevet en ny forbindelse med den generelle formel (I) hvor R1 og R2 uavhengig av hveran- dre er et hydrogenatom, en pivaloyl-, kapryloyl, lauroyl-, palmitoyl-, stearoyl-, linolyl-, dokosaheksaenoyl- eller benzoylgruppe, og R3 er et hydrogenatom eller en metylgruppe.
NO940710A 1993-03-02 1994-03-01 Nye Esculetin-derivater og farmasöytisk blanding NO940710L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6616493 1993-03-02
JP5351659A JPH06312925A (ja) 1993-03-02 1993-12-27 軟骨保護剤及び新規エスクレチン誘導体

Publications (2)

Publication Number Publication Date
NO940710D0 NO940710D0 (no) 1994-03-01
NO940710L true NO940710L (no) 1994-09-05

Family

ID=26407334

Family Applications (1)

Application Number Title Priority Date Filing Date
NO940710A NO940710L (no) 1993-03-02 1994-03-01 Nye Esculetin-derivater og farmasöytisk blanding

Country Status (9)

Country Link
US (1) US5455268A (no)
EP (1) EP0614896B1 (no)
JP (1) JPH06312925A (no)
KR (1) KR0135723B1 (no)
CN (1) CN1147297C (no)
AU (1) AU660870B2 (no)
CA (1) CA2116617C (no)
DE (1) DE69415570T2 (no)
NO (1) NO940710L (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4323409A1 (de) * 1993-07-13 1995-01-19 Boehringer Mannheim Gmbh Verwendung von Cumarinen und Carbostyrilen als PLA¶2¶-Inhibitoren, neue Cumarine und Carbostyrile, Verfahren zu ihrer Herstellung und Arzneimittel
CA2135850C (en) * 1993-11-15 1999-12-21 Koju Watanabe Esculetin derivatives, and method for manufacture thereof, use thereof, and pharmaceutical composition
JP2902318B2 (ja) * 1994-12-28 1999-06-07 呉羽化学工業株式会社 エスクレチン誘導体、その製造方法及びマトリックスメタロプロテアーゼ阻害剤
GB9609024D0 (en) 1996-05-01 1996-07-03 Idg Uk Ltd Compounds
WO1998004572A1 (fr) * 1996-07-31 1998-02-05 Kureha Chemical Industry Co., Ltd. Nouveaux derives de coumarine et glycosides, et procedes pour la preparation de ces composes
AU7781398A (en) 1997-06-04 1998-12-21 Freeman Group Of Hospitals Nhs Trust Identification of salmonella
JP2000119181A (ja) 1998-10-06 2000-04-25 Kureha Chem Ind Co Ltd エスクレチン及びその誘導体の放出制御経口製剤
US7067144B2 (en) * 1998-10-20 2006-06-27 Omeros Corporation Compositions and methods for systemic inhibition of cartilage degradation
CN1186336C (zh) * 2002-08-29 2005-01-26 成都迪康药物研究所 秦皮总香豆素的制备方法及其在制药中的应用
WO2005091960A2 (en) * 2004-03-05 2005-10-06 Rush University Medical Center Method for inhibiting fibrocartilage degradation
CN100428934C (zh) * 2006-09-07 2008-10-29 中国人民解放军第二军医大学 香豆素类化合物在制备诱导神经干细胞定向分化药物中的应用
CN104557831B (zh) * 2015-02-11 2016-03-23 施维雅(青岛)生物制药有限公司 七叶内酯衍生物及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2276819A1 (fr) * 1974-07-05 1976-01-30 Fabre Sa Pierre Facteurs p lipophile a action anti-inflammatoire locale utilisables dans le traitement de syndromes dermatologiques

Also Published As

Publication number Publication date
DE69415570T2 (de) 1999-06-24
CN1101259A (zh) 1995-04-12
NO940710D0 (no) 1994-03-01
AU660870B2 (en) 1995-07-06
JPH06312925A (ja) 1994-11-08
CN1147297C (zh) 2004-04-28
CA2116617C (en) 2001-02-20
KR0135723B1 (ko) 1998-04-23
AU5643894A (en) 1994-09-15
EP0614896B1 (en) 1998-12-30
DE69415570D1 (de) 1999-02-11
EP0614896A1 (en) 1994-09-14
US5455268A (en) 1995-10-03
CA2116617A1 (en) 1994-09-03
KR940021058A (ko) 1994-10-17

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