NO940373L - Ikke-belagte tabletter og fremgangsmåte for fremstilling av disse - Google Patents

Ikke-belagte tabletter og fremgangsmåte for fremstilling av disse

Info

Publication number
NO940373L
NO940373L NO940373A NO940373A NO940373L NO 940373 L NO940373 L NO 940373L NO 940373 A NO940373 A NO 940373A NO 940373 A NO940373 A NO 940373A NO 940373 L NO940373 L NO 940373L
Authority
NO
Norway
Prior art keywords
oily
fatty substance
excipient
compression
active ingredient
Prior art date
Application number
NO940373A
Other languages
English (en)
Other versions
NO940373D0 (no
Inventor
Hiroshi Matoba
Hiroyoshi Koyama
Junichi Kikuta
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO940373D0 publication Critical patent/NO940373D0/no
Publication of NO940373L publication Critical patent/NO940373L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2210/00—Fluid
    • F04C2210/26—Refrigerants with particular properties, e.g. HFC-134a

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Trykkstøptbar sammensetning omfattende en aktiv ingrediens, en eksipiens og et oljeaktig eller fettaktig stoff med et lavere smeltepunkt på omkring 20 til 90'C, blir trykkstøpt til ikke-belagte tabletter uten belegging for å forbedre slitasjemotstanden. Det oljeaktige eller fettaktige stoffet omfatter en høyere fettsyre eller et salt av denne, en voks, en fett- syreester, en herdet olje, et polyalkylenoksyd osv., og mengden av de.tte er omkring 0,01 til 10 vekt-*. Sammensetningen kan omfatte (1) et granulert pulver inneholdende den aktive Ingrediensen og eksipiensen, og det pulverformige eller granulære oljeaktige eller fettaktige stoffet med et lavere smeltepunkt, eller (2) et granulert pulver inneholdende den aktive ingredien- sen ,, eksipiensen og nevnte oljeaktige eller fettaktige stoff. Trykkstøping av sammensetningen forbedrer sli.tasjemotstanden til tabletten og hemmer signifikant utviklingen av pulver ved slitasje eller avriving selv når det oljeaktige eller fettaktige stoffet blir benyttet l en så liten mengde som omkring 0,1 til 0,5 vekt-*.
NO940373A 1993-02-10 1994-02-04 Ikke-belagte tabletter og fremgangsmåte for fremstilling av disse NO940373L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4595893 1993-02-10

Publications (2)

Publication Number Publication Date
NO940373D0 NO940373D0 (no) 1994-02-04
NO940373L true NO940373L (no) 1994-08-11

Family

ID=12733779

Family Applications (1)

Application Number Title Priority Date Filing Date
NO940373A NO940373L (no) 1993-02-10 1994-02-04 Ikke-belagte tabletter og fremgangsmåte for fremstilling av disse

Country Status (10)

Country Link
US (1) US5456920A (no)
EP (1) EP0610854B1 (no)
KR (1) KR940019294A (no)
CN (1) CN1106652A (no)
AT (1) ATE191846T1 (no)
CA (1) CA2115308C (no)
DE (1) DE69423990T2 (no)
FI (1) FI940585A (no)
NO (1) NO940373L (no)
TW (1) TW272942B (no)

Families Citing this family (43)

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EP0553777B1 (en) * 1992-01-29 2002-04-24 Takeda Chemical Industries, Ltd. Fast dissolving tablet and its production
TW466119B (en) * 1994-02-28 2001-12-01 Janssen Pharmaceutica Nv Film coated tablet of paracetamol and domperidone
GB9421836D0 (en) * 1994-10-28 1994-12-14 Scherer Corp R P Process for preparing solid pharmaceutical dosage forms of hydrophobic substances
AU717764B2 (en) * 1996-05-02 2000-03-30 Taisho Pharmaceutical Co., Ltd. Suspension of sparingly water-soluble acidic drug
TW592727B (en) 1997-04-04 2004-06-21 Chugai Pharmaceutical Co Ltd Phosphate-binding polymer preparations
AU1234399A (en) * 1997-11-25 1999-06-15 Bayer Aktiengesellschaft Sustained release formulations comprising alpha-glucosidase-i nhibitors
WO1999050217A1 (en) * 1998-03-31 1999-10-07 Bayer Aktiengesellschaft Valiolone, a method of preparing it, and its use to prepare acarbose and voglibose
CH689452C1 (de) * 1998-04-15 2004-11-30 Marcel Christian Wegmueller Verfahren zur Verhinderung von zementbedingten ablagerungen in einem Bauwerksentwaesserungssystem.
US8124630B2 (en) 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
JP2002534468A (ja) 1999-01-13 2002-10-15 バイエル コーポレイション ｐ３８キナーゼ阻害剤としてのω−カルボキシアリール置換ジフェニル尿素
ES2307482T3 (es) * 1999-02-10 2008-12-01 Pfizer Products Inc. Dispersiones farmaceuticas solidas.
US20020071864A1 (en) * 1999-03-25 2002-06-13 Yuhan Corporation Rapidly disintegrable tablet for oral administration
MXPA01012659A (es) * 1999-06-07 2003-09-04 Altana Pharma Ag Nueva forma de administracion y preparacion que comprende un compuesto activo labil acido.
CA2383212C (en) 1999-09-02 2008-11-25 Nostrum Pharmaceuticals, Inc. Controlled release oral dosage suitable for oral administration
US20100196466A1 (en) * 2000-06-06 2010-08-05 Capricorn Pharma Inc. Drug delivery system
US20070059367A1 (en) * 2000-06-06 2007-03-15 Cherukuri S R Drug Delivery System and Associated Methods
US20080058424A1 (en) * 2002-05-23 2008-03-06 Cephalon, Inc. Novel pharmaceutical formulations of modafinil
US7052706B2 (en) * 2001-06-08 2006-05-30 Nostrum Pharmaceuticals, Inc. Control release formulation containing a hydrophobic material as the sustained release agent
US6660292B2 (en) * 2001-06-19 2003-12-09 Hf Flavoring Technology Llp Rapidly disintegrating flavored film for precooked foods
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
US6982094B2 (en) 2001-09-28 2006-01-03 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
MXPA04002980A (es) 2001-09-28 2005-06-20 Johnson & Johnson Formas de dosificacion que tienen un nucleo interior y coraza exterior con diferentes formas.
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US7323192B2 (en) * 2001-09-28 2008-01-29 Mcneil-Ppc, Inc. Immediate release tablet
US6837696B2 (en) * 2001-09-28 2005-01-04 Mcneil-Ppc, Inc. Apparatus for manufacturing dosage forms
WO2003068228A1 (en) 2002-02-11 2003-08-21 Bayer Pharmaceuticals Corporation Aryl ureas with angiogenesis inhibiting activity
US7011688B2 (en) * 2002-05-10 2006-03-14 C.R. Bard, Inc. Prosthetic repair fabric
US20040116532A1 (en) 2002-09-13 2004-06-17 Craig Heacock Pharmaceutical formulations of modafinil
US7807197B2 (en) * 2002-09-28 2010-10-05 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
US7557129B2 (en) 2003-02-28 2009-07-07 Bayer Healthcare Llc Cyanopyridine derivatives useful in the treatment of cancer and other disorders
US20070148229A1 (en) * 2003-04-24 2007-06-28 Jagotec Ag Tablet with coloured core
PT1636585E (pt) 2003-05-20 2008-03-27 Bayer Pharmaceuticals Corp Diarilureias com actividade inibidora de cinase
US8637553B2 (en) 2003-07-23 2014-01-28 Bayer Healthcare Llc Fluoro substituted omega-carboxyaryl diphenyl urea for the treatment and prevention of diseases and conditions
FR2862187B1 (fr) * 2003-11-19 2006-02-24 Sbm Dev Nouvelles compositions agrochimiques et leur procede de fabrication
FR2867025B1 (fr) * 2004-03-05 2006-06-02 Sbm Dev Compositions agrochimiques solides a desagregation rapide
US8673352B2 (en) 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
DE102005028696A1 (de) * 2005-06-21 2006-12-28 Pulmotec Gmbh Verwendung eines Hilfsstoffs zur Einstellung der Abrasionsfestigkeit eines verfestigten Wirkstoffpräparats
MY149863A (en) 2006-08-03 2013-10-31 Nitec Pharma Ag Delayed-release glucocorticoid treatment of rheumatoid disease
TW200829286A (en) * 2006-09-06 2008-07-16 Genzyme Corp Polystyrene sulfonate polymer tablets, their preparation and use
JP5410290B2 (ja) * 2006-10-27 2014-02-05 エフ エム シー コーポレーション 共処理組成物とその製造方法、打錠可能な錠剤処方物、錠剤の製造方法及び錠剤
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same
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WO2019246384A1 (en) 2018-06-21 2019-12-26 Aquestive Therapeutics, Inc. System and method for making personalized individual unit doses containing pharmaceutical actives

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* Cited by examiner, † Cited by third party
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EP0070127A3 (en) * 1981-07-10 1983-08-17 Beecham Group Plc Tablets
JPH01308231A (ja) * 1988-06-03 1989-12-12 Takeda Chem Ind Ltd 安定化された医薬組成物および製造法
JPH0425926A (ja) * 1990-05-22 1992-01-29 Toshiba Corp 情報処理装置
TW284688B (no) * 1991-11-20 1996-09-01 Takeda Pharm Industry Co Ltd

Also Published As

Publication number Publication date
US5456920A (en) 1995-10-10
CA2115308C (en) 2004-05-11
EP0610854A1 (en) 1994-08-17
CA2115308A1 (en) 1994-08-11
FI940585A (fi) 1994-08-11
NO940373D0 (no) 1994-02-04
DE69423990T2 (de) 2000-08-17
ATE191846T1 (de) 2000-05-15
EP0610854B1 (en) 2000-04-19
CN1106652A (zh) 1995-08-16
KR940019294A (ko) 1994-09-14
DE69423990D1 (de) 2000-05-25
TW272942B (no) 1996-03-21
FI940585A0 (fi) 1994-02-09

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