NO932033L - 7-substituerte-6-fluor-1,4-dihydro-4-okso-kinolin-3-karboksylsyreforbindelser - Google Patents

7-substituerte-6-fluor-1,4-dihydro-4-okso-kinolin-3-karboksylsyreforbindelser

Info

Publication number
NO932033L
NO932033L NO93932033A NO932033A NO932033L NO 932033 L NO932033 L NO 932033L NO 93932033 A NO93932033 A NO 93932033A NO 932033 A NO932033 A NO 932033A NO 932033 L NO932033 L NO 932033L
Authority
NO
Norway
Prior art keywords
group
substituted
quinoline
dihydro
oxo
Prior art date
Application number
NO93932033A
Other languages
English (en)
Other versions
NO932033D0 (no
NO305479B1 (no
Inventor
Rajeshwar Singh
Inder Pal Singh
George Thomas
Maya Prakash Singh
Ronald George Micetic
Fathi-Afshar
Ab Edmonton
Original Assignee
Synphar Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synphar Lab Inc filed Critical Synphar Lab Inc
Publication of NO932033D0 publication Critical patent/NO932033D0/no
Publication of NO932033L publication Critical patent/NO932033L/no
Publication of NO305479B1 publication Critical patent/NO305479B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO932033A 1990-12-05 1993-06-03 AnalogifremgangsmÕte for fremstilling av 1-cyklopropyl-6-fluor-7-[3(S)-(1,2,3-triazol-1-yl)-pyrrolidin-1-yl]-1,4-dihydro-4-okso-1,8-naftyridin-3-karboksylsyre NO305479B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62171690A 1990-12-05 1990-12-05
PCT/CA1991/000435 WO1992010492A1 (en) 1990-12-05 1991-12-05 7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds useful as antibacterial agents

Publications (3)

Publication Number Publication Date
NO932033D0 NO932033D0 (no) 1993-06-03
NO932033L true NO932033L (no) 1993-06-03
NO305479B1 NO305479B1 (no) 1999-06-07

Family

ID=24491336

Family Applications (1)

Application Number Title Priority Date Filing Date
NO932033A NO305479B1 (no) 1990-12-05 1993-06-03 AnalogifremgangsmÕte for fremstilling av 1-cyklopropyl-6-fluor-7-[3(S)-(1,2,3-triazol-1-yl)-pyrrolidin-1-yl]-1,4-dihydro-4-okso-1,8-naftyridin-3-karboksylsyre

Country Status (12)

Country Link
EP (1) EP0561850B1 (no)
JP (1) JPH06507149A (no)
KR (1) KR100196440B1 (no)
AT (1) ATE194612T1 (no)
CA (1) CA2099591C (no)
DE (1) DE69132314T2 (no)
FI (1) FI932596A (no)
HU (2) HUT64058A (no)
NO (1) NO305479B1 (no)
NZ (1) NZ240883A (no)
WO (1) WO1992010492A1 (no)
ZA (1) ZA919601B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342846A (en) * 1990-12-05 1994-08-30 Synphar Laboratories, Inc. 7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds and 7-(substituted triazolyl pyrrolidin-1-yl) 4-oxoquinoline-3-carboxylic acid derivatives useful as antibacterial agents
US5221676A (en) * 1992-02-06 1993-06-22 Warner-Lambert Company 7-substituted quinolones and naphthyridones as antibacterial agents
KR960003616B1 (ko) * 1992-07-23 1996-03-20 재단법인 한국화학연구소 우수한 항균작용을 갖는 신규한 피리돈 카르복실산 유도체 및 그의 제조방법
TW252107B (no) * 1993-08-27 1995-07-21 Hokuriku Pharmacetical Co Ltd
WO1996022988A1 (fr) * 1995-01-24 1996-08-01 Hokuriku Seiyaku Co., Ltd. Derives de l'acide quiloleine carboxylique
US6436974B1 (en) * 1999-06-02 2002-08-20 Warner-Lambert Company Amino heterocycles useful as pharmaceutical agents
US6821969B2 (en) * 2001-02-13 2004-11-23 Pharmacia & Upjohn Company Thioxazinoquinolones as antiviral agents
RU2606131C2 (ru) 2011-05-13 2017-01-10 Эррэй Биофарма Инк. СОЕДИНЕНИЯ ПИРРОЛИДИНИЛМОЧЕВИНЫ И ПИРРОЛИДИНИЛТИОМОЧЕВИНЫ КАК ИНГИБИТОРЫ КИНАЗЫ TrkA
TW201718506A (zh) 2011-08-31 2017-06-01 大塚製藥股份有限公司 喹啉酮化合物
JP6577479B2 (ja) * 2014-02-27 2019-09-18 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ Ｎａｖ チャンネル阻害剤としてのヘテロ環化合物及びその使用
GB201708606D0 (en) * 2017-05-30 2017-07-12 King's College London Antibiotic resistance breakers
US11034669B2 (en) 2018-11-30 2021-06-15 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58742B1 (en) * 1984-07-20 1993-11-05 Warner Lambert Co Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
DE3519286A1 (de) * 1985-05-30 1986-12-04 Bayer Ag, 5090 Leverkusen 7-azolyl-1-cyclopropyl-1,4-dihydro-4-oxo-3- chinolincarbonsaeuren und -1,8-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
AU5123690A (en) * 1989-03-13 1990-09-13 Bristol-Myers Squibb Company 5-substituted-1,4-dihydro-4-oxo-nephthyridine-3-carboxylate antibacterial agents
NO177302C (no) * 1989-03-16 1995-08-23 Esteve Labor Dr Analogifremgangsmåte til fremstilling av terapeutisk aktive substituerte azetidinylkinolon(naftyridon)karboksylsyrederivater

Also Published As

Publication number Publication date
NO932033D0 (no) 1993-06-03
HUT64058A (en) 1993-11-29
EP0561850B1 (en) 2000-07-12
ZA919601B (en) 1992-10-28
DE69132314D1 (de) 2000-08-17
FI932596A0 (fi) 1993-06-07
KR100196440B1 (ko) 1999-06-15
AU9021091A (en) 1992-07-08
CA2099591A1 (en) 1992-06-06
DE69132314T2 (de) 2000-12-14
ATE194612T1 (de) 2000-07-15
HU9301648D0 (en) 1993-09-28
FI932596A (fi) 1993-08-04
AU666296B2 (en) 1996-02-08
WO1992010492A1 (en) 1992-06-25
NO305479B1 (no) 1999-06-07
NZ240883A (en) 1994-09-27
CA2099591C (en) 2002-11-12
EP0561850A1 (en) 1993-09-29
JPH06507149A (ja) 1994-08-11

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