NO931886L - Anvendelse av aica ribocid-forbindelser for behandling/prevensjon av vevskader som skyldes nedsatt blodstroemning - Google Patents

Anvendelse av aica ribocid-forbindelser for behandling/prevensjon av vevskader som skyldes nedsatt blodstroemning

Info

Publication number
NO931886L
NO931886L NO93931886A NO931886A NO931886L NO 931886 L NO931886 L NO 931886L NO 93931886 A NO93931886 A NO 93931886A NO 931886 A NO931886 A NO 931886A NO 931886 L NO931886 L NO 931886L
Authority
NO
Norway
Prior art keywords
aica
ribocid
prevention
compounds
treatment
Prior art date
Application number
NO93931886A
Other languages
English (en)
Other versions
NO931886D0 (no
Inventor
Harry Edward Gruber
Kevin Michael Mullane
Paul Kevin Laikind
Original Assignee
Gensia Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gensia Pharma filed Critical Gensia Pharma
Publication of NO931886D0 publication Critical patent/NO931886D0/no
Publication of NO931886L publication Critical patent/NO931886L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Metoder for å forhindre vevskade assosiert med nedsatt blodstrømning i et menneske ved tilførsel av AICA ribosid eller en forløpermedisin derav i en mengde som tilveiebringer en blodplasmakonsentrasjon mellom l ug/ml og 20 ug/ml AICA ribosid i en tid tilstrekkelig til å redusere faren for den nevnte vevskade i det nevnte menneske. Metoder for å for- hindre et skadelig klinisk resultat, som et skadelig kardio- vaskulært og/eller cerebrovaskulært tilfelle i en pasient i fare for et slikt resultat ved tilførsel av AICA ribosid eller en forløpermedisin derav i en mengde som tilveiebringer en blodplasmakonsentrasjon på mellom l ug/ml og 20 Ug/ml AICA ribosid i en tid tilstrekkelig til å redusere faren for den nevnte pasient.
NO93931886A 1991-09-30 1993-05-25 Anvendelse av aica ribocid-forbindelser for behandling/prevensjon av vevskader som skyldes nedsatt blodstroemning NO931886L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77002391A 1991-09-30 1991-09-30
US94910192A 1992-09-21 1992-09-21
PCT/US1992/008304 WO1993006833A1 (en) 1991-09-30 1992-09-28 Use of aica riboside compounds for the treatment and prevention of tissue damage due to decreased blood flow

Publications (2)

Publication Number Publication Date
NO931886D0 NO931886D0 (no) 1993-05-25
NO931886L true NO931886L (no) 1993-07-27

Family

ID=27118261

Family Applications (1)

Application Number Title Priority Date Filing Date
NO93931886A NO931886L (no) 1991-09-30 1993-05-25 Anvendelse av aica ribocid-forbindelser for behandling/prevensjon av vevskader som skyldes nedsatt blodstroemning

Country Status (9)

Country Link
US (1) US5817640A (no)
EP (2) EP0560967A1 (no)
JP (1) JPH06503359A (no)
AU (2) AU2762792A (no)
CA (1) CA2096825A1 (no)
IL (1) IL103294A0 (no)
MX (1) MX9205568A (no)
NO (1) NO931886L (no)
WO (1) WO1993006833A1 (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE120340T1 (de) * 1991-10-31 1995-04-15 Unilever Nv Mit dem löffel essbare, nichtmilchhaltige saure sahne.
WO1999024038A1 (en) * 1997-11-07 1999-05-20 Johns Hopkins University Methods for treatment of disorders of cardiac contractility
AU7629200A (en) * 1999-08-09 2001-03-05 Trustees Of Boston University Method of maintaining vascular integrity using aicar (5-amino-4-imidazole riboside) and related compounds
AU2001268236A1 (en) * 2000-06-06 2001-12-17 Trustees Of Boston University Use of aicar and related compounds
US20030212034A1 (en) * 2001-06-11 2003-11-13 Winder William W Method of treatment of obesity and paralyzed muscle and ergogenic aids
ES2192495B1 (es) * 2002-03-21 2005-02-16 Universidad De Barcelona Nuevo uso terapeutico del ribosido de 5-aminoimidazol-4-carboxamida (acadesina).
ES2493840T3 (es) 2002-10-07 2014-09-12 Zymogenetics, Inc. Procedimiento de administración de FGF-18
US20040199114A1 (en) * 2003-04-01 2004-10-07 Alsius Corporation Intravascular heat exchange catheter with tissue preservative
EP2594273A1 (en) 2005-03-28 2013-05-22 Pericor Therapeutics, Inc. Methods, compositions, and formulations for preventing or reducing adverse effects in a patient
US20070082859A1 (en) * 2005-10-07 2007-04-12 Stover Richard R Formulations of AICA riboside
WO2008086341A1 (en) * 2007-01-09 2008-07-17 Pericor Therapeutics, Inc. Methods. compositions, and formulations for preventing or reducing adverse effects in a patient
WO2009093925A1 (en) * 2008-01-23 2009-07-30 United Technologies Ut Ag COSMETIC COMPOSITIONS COMPRISING 5-AMINO-L-β-D- RIBOFURANOSYL-LH-IMIDAZOLE-4-CARBOXAMIDE OR DERIVATIVES, OR SALTS THEREOF
EP2349284B1 (en) 2008-10-03 2016-11-23 Pericor Therapeutics, Inc. Treatment of acute decompensated heart failure
US8895520B2 (en) 2011-10-26 2014-11-25 Universite Nice Sophia Antipolis Method for treating a human patent suffering from Myeloid Neoplasias using 5-aminoimidazole-4-carboxamide
JP7376951B2 (ja) 2018-08-06 2023-11-09 スカイラーク バイオサイエンス エルエルシー Ａｍｐ活性化プロテインキナーゼ活性化化合物およびその使用
US11779590B2 (en) 2020-10-30 2023-10-10 Skylark Bioscience Llc AMP-activated protein kinase activating compounds and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4575498A (en) * 1983-07-21 1986-03-11 Duke University Method for restoring depleted purine nucleotide pools
EP0262125B1 (en) * 1986-03-27 1996-03-27 Gensia, Inc. AICA riboside for the prophylactic treatment of diseases with restricted blood flow.
US5008251A (en) * 1986-03-27 1991-04-16 The Regents Of The University Of California Method of treating autism
US4912092A (en) * 1986-03-27 1990-03-27 The Regents Of The University Of California Methods for increasing extracellular adenosine and for stabilizing mast cells
US5030623A (en) * 1986-03-27 1991-07-09 The Regents Of The University Of California Methods for increasing extracellular adenosine and for stabilizing mast cells
US5118601A (en) * 1986-03-27 1992-06-02 The Regents Of The University Of California Method of screening purine nucleoside compounds or analogs for the ability to enhance the cellular synthesis and release of adenosine
IL93164A0 (en) * 1989-01-24 1990-11-05 Gensia Pharma Purine nucleosides and their medical use
US5187162A (en) * 1989-09-15 1993-02-16 Gensia Pharmaceuticals Methods of treating neurodegenerative conditions
IL99125A0 (en) * 1990-08-10 1992-07-15 Gensia Pharma Derivatives of imidazole analog of aica riboside and their use
IL99124A (en) * 1990-08-10 1998-02-22 Gensia Pharma Substituted imidazole analogs of aica riboside
IL108524A0 (en) * 1993-02-03 1994-05-30 Gensia Inc Imidazodiazepine analogs

Also Published As

Publication number Publication date
NO931886D0 (no) 1993-05-25
EP0535884A1 (en) 1993-04-07
MX9205568A (es) 1994-03-31
US5817640A (en) 1998-10-06
AU2762792A (en) 1993-05-03
EP0560967A1 (en) 1993-09-22
JPH06503359A (ja) 1994-04-14
WO1993006833A1 (en) 1993-04-15
IL103294A0 (en) 1993-05-13
AU4210696A (en) 1996-04-26
CA2096825A1 (en) 1993-03-31

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