NO903088L - PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE DIAZEPINE DERIVATIVES. - Google Patents

PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE DIAZEPINE DERIVATIVES.

Info

Publication number
NO903088L
NO903088L NO90903088A NO903088A NO903088L NO 903088 L NO903088 L NO 903088L NO 90903088 A NO90903088 A NO 90903088A NO 903088 A NO903088 A NO 903088A NO 903088 L NO903088 L NO 903088L
Authority
NO
Norway
Prior art keywords
procedure
preparation
therapeutic active
diazepine derivatives
diazepine
Prior art date
Application number
NO90903088A
Other languages
Norwegian (no)
Other versions
NO903088D0 (en
Inventor
Karl-Heinz Weber
Werner Stransky
Gerhard Walther
Ulrike Kuefner-Muehl
Hubert Heuer
Franz Birke
Gojko Muacevic
Wolf-Dietrich Bechtel
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of NO903088D0 publication Critical patent/NO903088D0/en
Publication of NO903088L publication Critical patent/NO903088L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/49Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with carbon monoxide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NO90903088A 1989-07-12 1990-07-11 PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE DIAZEPINE DERIVATIVES. NO903088L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3922944 1989-07-12
DE4011345 1990-04-07

Publications (2)

Publication Number Publication Date
NO903088D0 NO903088D0 (en) 1990-07-11
NO903088L true NO903088L (en) 1991-01-14

Family

ID=25882911

Family Applications (1)

Application Number Title Priority Date Filing Date
NO90903088A NO903088L (en) 1989-07-12 1990-07-11 PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE DIAZEPINE DERIVATIVES.

Country Status (14)

Country Link
EP (1) EP0407955A1 (en)
JP (1) JPH03215489A (en)
KR (1) KR910002863A (en)
AU (1) AU636155B2 (en)
CA (1) CA2020806A1 (en)
FI (1) FI903509A0 (en)
HU (1) HUT59144A (en)
IE (1) IE902526A1 (en)
IL (1) IL95045A0 (en)
NO (1) NO903088L (en)
NZ (1) NZ234476A (en)
PL (1) PL286019A1 (en)
PT (1) PT94673A (en)
YU (1) YU133090A (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI95708C (en) * 1988-10-31 1996-03-11 Eisai Co Ltd Analogous process for preparing a 1,4-diazepine derivative and its pharmaceutically acceptable salt
DE4027470A1 (en) * 1990-08-30 1992-03-05 Boehringer Ingelheim Kg NEW HETRAZEPINOIDE AMIDE
DE4101146A1 (en) * 1991-01-16 1992-07-23 Boehringer Ingelheim Kg NEW DIAZEPINE SUBSTITUTED IN 6-POSITION, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICAMENT
DE4107521A1 (en) * 1991-03-08 1992-09-10 Boehringer Ingelheim Kg NEW ACYLAMINOSUBSTITUTED HETRAZEPINE
JP3094453B2 (en) * 1996-09-13 2000-10-03 ウェルファイド株式会社 Thienotriazolodiazepine compounds and their pharmaceutical uses
US6323214B1 (en) 1997-10-29 2001-11-27 Medco Research, Inc Allosteric adenosine receptor modulators
US5939432A (en) 1997-10-29 1999-08-17 Medco Research, Inc. Thiophenes useful for modulating the adenosine receptor
US6727258B2 (en) 1997-10-29 2004-04-27 King Pharmaceutical Research & Development, Inc. Allosteric adenosine receptor modulators
US6184226B1 (en) 1998-08-28 2001-02-06 Scios Inc. Quinazoline derivatives as inhibitors of P-38 α
JP5008796B2 (en) * 2001-01-19 2012-08-22 ダイト株式会社 Method for producing aromatic carboxylic acid
TWI447120B (en) * 2005-05-30 2014-08-01 Mitsubishi Tanabe Pharma Corp Thienotriazolodiazepine compound and a medicinal use thereof
CN105582014B (en) 2010-05-14 2019-06-14 达那-法伯癌症研究所 For treating the composition and method of leukaemia
US9301962B2 (en) 2010-05-14 2016-04-05 Baylor College Of Medicine Male contraceptive compositions and methods of use
DK2571503T3 (en) 2010-05-14 2015-04-20 Dana Farber Cancer Inst Inc COMPOSITIONS AND THEIR USE IN THE TREATMENT OF NEOPLASIA, INFLAMMATORY DISEASE AND OTHER DISORDERS
AR084070A1 (en) 2010-12-02 2013-04-17 Constellation Pharmaceuticals Inc BROMODOMINIUM INHIBITORS AND USES OF THE SAME
WO2012075456A1 (en) 2010-12-02 2012-06-07 Constellation Pharmaceuticals Bromodomain inhibitors and uses thereof
EP2705039B1 (en) 2011-05-04 2017-07-26 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
EP2721031B1 (en) 2011-06-17 2016-01-20 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
WO2013184878A1 (en) 2012-06-06 2013-12-12 Constellation Pharmaceuticals, Inc. Benzo [b] isoxazoloazepine bromodomain inhibitors and uses thereof
TWI602820B (en) 2012-06-06 2017-10-21 星宿藥物公司 Bromodomain inhibitors and uses thereof
MX2016001037A (en) 2013-07-25 2016-11-10 Dana Farber Cancer Inst Inc Inhibitors of transcription factors and uses thereof.
RU2016122654A (en) 2013-11-08 2017-12-14 Дана-Фарбер Кэнсер Инститьют, Инк. COMBINED THERAPY OF A MALIGNANT TUMOR USING BRODOMODOMENE AND EXTRATERMINAL (BET) PROTEIN INHIBITORS
WO2015117053A1 (en) 2014-01-31 2015-08-06 Dana-Farber Cancer Institute, Inc. Diaminopyrimidine benzenesulfone derivatives and uses thereof
WO2015117087A1 (en) 2014-01-31 2015-08-06 Dana-Farber Cancer Institute, Inc. Uses of diazepane derivatives
CN106456653A (en) 2014-02-28 2017-02-22 腾沙治疗公司 Treatment of conditions associated with hyperinsulinaemia
US9969747B2 (en) 2014-06-20 2018-05-15 Constellation Pharmaceuticals, Inc. Crystalline forms of 2-((4S)-6-(4-chlorophenyl)-1-methyl-4H-benzo[C]isoxazolo[4,5-e]azepin-4-yl)acetamide
EP3177147A4 (en) 2014-08-08 2018-01-24 Dana-Farber Cancer Institute, Inc. Dihydropteridinone derivatives and uses thereof
CN106715437A (en) 2014-08-08 2017-05-24 达纳-法伯癌症研究所股份有限公司 Diazepane derivatives and uses thereof
KR20170068597A (en) 2014-10-27 2017-06-19 텐샤 세러퓨틱스 인코포레이티드 Bromodomain inhibitors
AU2016276963C1 (en) 2015-06-12 2021-08-05 Dana-Farber Cancer Institute, Inc. Combination therapy of transcription inhibitors and kinase inhibitors
SG10202007099TA (en) 2015-09-11 2020-08-28 Dana Farber Cancer Inst Inc Acetamide thienotriazoldiazepines and uses thereof
AU2016319116B2 (en) 2015-09-11 2020-10-01 Dana-Farber Cancer Institute, Inc. Cyano thienotriazolodiazepines and uses thereof
KR20180081809A (en) 2015-11-25 2018-07-17 다나-파버 캔서 인스티튜트 인크. Divalent bromo domain inhibitors and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2712951A1 (en) * 1977-03-24 1978-10-05 Bosch Gmbh Robert BIMETAL WITH AN ELECTRIC HEATING ELEMENT
DE3701344A1 (en) * 1986-01-21 1987-07-23 Boehringer Ingelheim Kg Novel thieno-1,4-diazepines
ES2037013T3 (en) * 1986-01-21 1993-06-16 Boehringer Ingelheim Kg PROCEDURE FOR PREPARING TIENO-1,4-DIAZEPINES.
DE3610848A1 (en) * 1986-04-01 1987-10-15 Boehringer Ingelheim Kg NEW 1,4-DIAZEPINE
DE3624779C2 (en) * 1986-07-22 1996-03-07 Boehringer Ingelheim Kg Process for the preparation of thieno-triazolo-1,4-diazepino-2-carboxylic acid amides
DE3724031A1 (en) * 1986-07-22 1988-01-28 Boehringer Ingelheim Kg Novel hetrazepines and process for their preparation

Also Published As

Publication number Publication date
NO903088D0 (en) 1990-07-11
EP0407955A1 (en) 1991-01-16
FI903509A0 (en) 1990-07-11
NZ234476A (en) 1992-08-26
YU133090A (en) 1993-10-20
HUT59144A (en) 1992-04-28
PT94673A (en) 1991-03-20
AU636155B2 (en) 1993-04-22
CA2020806A1 (en) 1991-01-13
PL286019A1 (en) 1991-10-21
AU5892490A (en) 1991-01-17
HU904169D0 (en) 1990-12-28
JPH03215489A (en) 1991-09-20
IE902526A1 (en) 1991-02-13
IL95045A0 (en) 1991-06-10
KR910002863A (en) 1991-02-26

Similar Documents

Publication Publication Date Title
NO903088D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE DIAZEPINE DERIVATIVES.
NO904694L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE IMIDAZOLD DERIVATIVES.
NO901684L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 3-SUBSTITUTED-2-OXINDOL DERIVATIVES.
NO894630D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE KINUCLIDINE DERIVATIVES.
NO883974L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TETRAHYDRO-HYDROXYPYRANON DERIVATIVES.
NO904986L (en) ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE DIAZEPINE DERIVATIVES.
NO870526D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE DICHLORANILIN DERIVATIVES.
NO893616L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TRICYCLIC COMPOUNDS.
NO890155D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE INDOLPIPERIDIN COMPOUNDS.
NO881762D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE BENZAZEPINE DERIVATIVES.
NO900697D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ACETAMIDE DERIVATIVES.
NO891723D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE CHINAZOLINE DERIVATIVES.
NO895220L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE BENZENE DERIVATIVES.
NO865012L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE BENZAZEPINE DERIVATIVES.
NO905327D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE CARBAMOIL OIL DERIVATIVES.
NO913187D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TRICYCLIC DERIVATIVES.
NO900972D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE NAFTALEN DERIVATIVES.
NO900942D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE AZACYCLOOKTADIEN DERIVATIVES.
NO890724D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TETRAAZAACENAPYLENE DERIVATIVES.
NO904470D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE BENZODIAZEPINE DERIVATIVES.
NO890519D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE PROPANON DERIVATIVES.
NO880492D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TRICYCLIC TRIAZOLPYRIMIDINE DERIVATIVES.
NO891677D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE PHENETANOLAMINE DERIVATIVES.
NO890506L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE CHLORANILIN DERIVATIVES.
NO890502L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ETHANOLAMINE DERIVATIVES.