NO901430D0 - Fremgangsmaate til fremstilling av 4(3h)-pteridioner, og medikamenter inneholdende slike. - Google Patents

Fremgangsmaate til fremstilling av 4(3h)-pteridioner, og medikamenter inneholdende slike.

Info

Publication number: NO901430D0
Authority: NO; Norway
Prior art keywords: pteridions; procedure; preparation; medicines containing; medicines
Prior art date: 1989-03-30

Application number

NO901430A

Other languages

English (en)

Other versions

NO901430L (no

NO175100C (no

NO175100B (no

Inventor

Gerard Ferrand

Herve Dumas

Jean-Claude Depin

Yvette Quentin

Original Assignee

Lipha

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-03-30

Filing date

1990-03-29

Publication date

1990-03-29

1990-03-29 Application filed by Lipha filed Critical Lipha

1990-03-29 Publication of NO901430D0 publication Critical patent/NO901430D0/no

1990-10-01 Publication of NO901430L publication Critical patent/NO901430L/no

1994-05-24 Publication of NO175100B publication Critical patent/NO175100B/no

1994-08-31 Publication of NO175100C publication Critical patent/NO175100C/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Pulmonology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO901430A 1989-03-30 1990-03-29 Analogifremgangsmåte til fremstilling av terapeutisk aktive 4(3H)-pteridinoner NO175100C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8904193A FR2645152B1 (fr)	1989-03-30	1989-03-30	3h-pteridinones-4, procedes de preparation et medicaments les contenant

Publications (4)

Publication Number	Publication Date
NO901430D0 true NO901430D0 (no)	1990-03-29
NO901430L NO901430L (no)	1990-10-01
NO175100B NO175100B (no)	1994-05-24
NO175100C NO175100C (no)	1994-08-31

Family

ID=9380213

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO901430A NO175100C (no)	1989-03-30	1990-03-29	Analogifremgangsmåte til fremstilling av terapeutisk aktive 4(3H)-pteridinoner

Country Status (30)

Country	Link
US (1)	US5167949A (no)
EP (1)	EP0399856B1 (no)
JP (1)	JPH0725761B2 (no)
AR (1)	AR248278A1 (no)
AT (1)	ATE126229T1 (no)
AU (1)	AU630178B2 (no)
CA (1)	CA2013324C (no)
CZ (1)	CZ284679B6 (no)
DD (1)	DD296927A5 (no)
DE (1)	DE69021444T2 (no)
DK (1)	DK0399856T3 (no)
ES (1)	ES2078324T3 (no)
FR (1)	FR2645152B1 (no)
GE (1)	GEP19971023B (no)
GR (1)	GR3017245T3 (no)
HR (1)	HRP920759B1 (no)
HU (1)	HU208826B (no)
IE (1)	IE68689B1 (no)
IL (1)	IL93914A (no)
LV (1)	LV5821B4 (no)
MA (1)	MA21786A1 (no)
NO (1)	NO175100C (no)
NZ (1)	NZ233130A (no)
OA (1)	OA09441A (no)
PT (1)	PT93600B (no)
RU (1)	RU1836344C (no)
SI (1)	SI9010633B (no)
TN (1)	TNSN90040A1 (no)
YU (1)	YU47346B (no)
ZA (1)	ZA902397B (no)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5270465A (en) *	1989-03-30	1993-12-14	Lipha, Lyonnaise Industrille Pharmaceutique	4(3H)-pteridinone compounds
FR2772615B1 (fr)	1997-12-23	2002-06-14	Lipha	Comprime multicouche pour la liberation instantanee puis prolongee de substances actives
CA2458699C (en) *	2001-09-04	2010-10-19	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Novel dihydropteridinones, method for producing the same and the use thereof as medicaments
US6806272B2 (en)	2001-09-04	2004-10-19	Boehringer Ingelheim Pharma Kg	Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
FR2831789B1 (fr) *	2001-11-07	2004-01-23	Oreal	Procede et dispositif pour l'evaluation de la secheresse cutanee notamment
US6861422B2 (en)	2003-02-26	2005-03-01	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
DE102004029784A1 (de)	2004-06-21	2006-01-05	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue 2-Benzylaminodihydropteridinone, Verfahren zur deren Herstellung und deren Verwendung als Arzneimittel
DE102004033670A1 (de) *	2004-07-09	2006-02-02	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue Pyridodihydropyrazinone, Verfahren zu Ihrer Herstellung und Ihre Verwendung als Arzneimittel
US20060074088A1 (en)	2004-08-14	2006-04-06	Boehringer Ingelheim International Gmbh	Dihydropteridinones for the treatment of cancer diseases
US20060058311A1 (en)	2004-08-14	2006-03-16	Boehringer Ingelheim International Gmbh	Combinations for the treatment of diseases involving cell proliferation
US20060035903A1 (en) *	2004-08-14	2006-02-16	Boehringer Ingelheim International Gmbh	Storage stable perfusion solution for dihydropteridinones
US7759485B2 (en)	2004-08-14	2010-07-20	Boehringer Ingelheim International Gmbh	Process for the manufacture of dihydropteridinones
US7728134B2 (en)	2004-08-14	2010-06-01	Boehringer Ingelheim International Gmbh	Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament
EP1632493A1 (de)	2004-08-25	2006-03-08	Boehringer Ingelheim Pharma GmbH & Co.KG	Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
EP1630163A1 (de)	2004-08-25	2006-03-01	Boehringer Ingelheim Pharma GmbH & Co.KG	Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
DE102004058337A1 (de) *	2004-12-02	2006-06-14	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten
US7439358B2 (en)	2006-02-08	2008-10-21	Boehringer Ingelheim International Gmbh	Specific salt, anhydrous and crystalline form of a dihydropteridione derivative
CA2680775A1 (en) *	2007-03-23	2008-10-02	F. Hoffmann-La Roche Ag	Aza-pyridopyrimidinone derivatives
US8329695B2 (en)	2007-08-03	2012-12-11	Boehringer Ingelheim International Gmbh	Crystalline form of the free base N-[trans-4-[4-(cyclopropylmethyl)-1-piperazinyl]cyclohexyl]-4-[[(7r)-7-ethyl-5,6,7,8-tetrahydro-5-methyl-8-(1-methylethyl)-6-oxo-2-pteridinyl]amino]-3-methoxy-benzamide
US8546566B2 (en)	2010-10-12	2013-10-01	Boehringer Ingelheim International Gmbh	Process for manufacturing dihydropteridinones and intermediates thereof
US9358233B2 (en)	2010-11-29	2016-06-07	Boehringer Ingelheim International Gmbh	Method for treating acute myeloid leukemia
US9370535B2 (en)	2011-05-17	2016-06-21	Boehringer Ingelheim International Gmbh	Method for treatment of advanced solid tumors
US20150031699A1 (en)	2013-07-26	2015-01-29	Boehringer Ingelheim International Gmbh	Treatment of myelodysplastic syndrome
US9867831B2 (en)	2014-10-01	2018-01-16	Boehringer Ingelheim International Gmbh	Combination treatment of acute myeloid leukemia and myelodysplastic syndrome

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3159628A (en) *	1962-05-28	1964-12-01	Smith Kline French Lab	Pteridine-5-oxide derivatives
US3426019A (en) *	1962-06-29	1969-02-04	Smithkline Corp	Derivatives of pteridine and a method for their preparation
SE307365B (no) *	1966-05-28	1969-01-07	Yoshitomi Pharmaceutical
US3732224A (en) *	1969-10-20	1973-05-08	Sherwin Williams Co	Method of controlling plant growth and 3-substituted lumazines used in such method
US3819631A (en) *	1970-12-15	1974-06-25	May & Baker Ltd	Azapurinones
US3859287A (en) *	1971-05-05	1975-01-07	Walter Wesley Parish	Thiopteridines and process for producing same
DE2232098A1 (de) *	1972-06-30	1974-01-17	Boehringer Mannheim Gmbh	2-alkyl-4(3h)-pteridinone und verfahren zu ihrer herstellung
US4183934A (en) *	1978-10-16	1980-01-15	Abbott Laboratories	4-Hydroxy-7-(substituted)phenylpteridines
US4361700A (en) *	1980-05-20	1982-11-30	James S. Waldron	Pyridopyrimidinone derivatives

1989
- 1989-03-30 FR FR8904193A patent/FR2645152B1/fr not_active Expired - Lifetime
1990
- 1990-03-26 AU AU52218/90A patent/AU630178B2/en not_active Ceased
- 1990-03-27 AT AT90400827T patent/ATE126229T1/de not_active IP Right Cessation
- 1990-03-27 DE DE69021444T patent/DE69021444T2/de not_active Expired - Fee Related
- 1990-03-27 OA OA59755A patent/OA09441A/xx unknown
- 1990-03-27 DK DK90400827.3T patent/DK0399856T3/da active
- 1990-03-27 IL IL9391490A patent/IL93914A/en not_active IP Right Cessation
- 1990-03-27 EP EP90400827A patent/EP0399856B1/fr not_active Expired - Lifetime
- 1990-03-27 MA MA22052A patent/MA21786A1/fr unknown
- 1990-03-27 ES ES90400827T patent/ES2078324T3/es not_active Expired - Lifetime
- 1990-03-28 ZA ZA902397A patent/ZA902397B/xx unknown
- 1990-03-28 CA CA002013324A patent/CA2013324C/fr not_active Expired - Fee Related
- 1990-03-28 CZ CS901520A patent/CZ284679B6/cs not_active IP Right Cessation
- 1990-03-29 US US07/501,104 patent/US5167949A/en not_active Expired - Fee Related
- 1990-03-29 NO NO901430A patent/NO175100C/no not_active IP Right Cessation
- 1990-03-29 PT PT93600A patent/PT93600B/pt not_active IP Right Cessation
- 1990-03-29 AR AR90316504A patent/AR248278A1/es active
- 1990-03-29 SI SI9010633A patent/SI9010633B/sl not_active IP Right Cessation
- 1990-03-29 YU YU63390A patent/YU47346B/sh unknown
- 1990-03-29 HU HU901898A patent/HU208826B/hu not_active IP Right Cessation
- 1990-03-29 DD DD90339197A patent/DD296927A5/de unknown
- 1990-03-29 RU SU904743545A patent/RU1836344C/ru active
- 1990-03-29 NZ NZ233130A patent/NZ233130A/en unknown
- 1990-03-29 IE IE115790A patent/IE68689B1/en not_active IP Right Cessation
- 1990-03-30 JP JP2081429A patent/JPH0725761B2/ja not_active Expired - Fee Related
- 1990-03-30 TN TNTNSN90040A patent/TNSN90040A1/fr unknown
1992
- 1992-10-01 HR HRP-633/90A patent/HRP920759B1/xx not_active IP Right Cessation
1993
- 1993-03-11 GE GEAP1993603A patent/GEP19971023B/en unknown
1995
- 1995-08-30 GR GR950402356T patent/GR3017245T3/el unknown
1996
- 1996-07-18 LV LV960271A patent/LV5821B4/xx unknown

Also Published As

Publication number	Publication date
RU1836344C (ru)	1993-08-23
HU208826B (en)	1994-01-28
DE69021444D1 (de)	1995-09-14
SI9010633A (en)	1997-02-28
EP0399856B1 (fr)	1995-08-09
HUT53646A (en)	1990-11-28
PT93600A (pt)	1990-11-20
NZ233130A (en)	1992-01-29
AU5221890A (en)	1990-10-04
NO901430L (no)	1990-10-01
ATE126229T1 (de)	1995-08-15
DD296927A5 (de)	1991-12-19
ZA902397B (en)	1991-01-30
EP0399856A1 (fr)	1990-11-28
NO175100C (no)	1994-08-31
FR2645152B1 (fr)	1991-05-31
US5167949A (en)	1992-12-01
DK0399856T3 (da)	1995-09-18
NO175100B (no)	1994-05-24
LV5821B4 (lv)	1997-10-20
JPH02304089A (ja)	1990-12-17
IE68689B1 (en)	1996-07-10
HRP920759B1 (en)	1998-08-31
SI9010633B (sl)	1999-06-30
YU47346B (sh)	1995-01-31
MA21786A1 (fr)	1990-10-01
GR3017245T3 (en)	1995-11-30
CZ284679B6 (cs)	1999-02-17
OA09441A (fr)	1992-10-15
YU63390A (en)	1991-10-31
IL93914A (en)	1994-02-27
ES2078324T3 (es)	1995-12-16
IL93914A0 (en)	1990-12-23
AR248278A1 (es)	1995-07-12
CZ152090A3 (cs)	1998-11-11
CA2013324A1 (fr)	1990-09-30
FR2645152A1 (fr)	1990-10-05
DE69021444T2 (de)	1996-03-14
PT93600B (pt)	1996-03-29
LV5821A4 (lv)	1997-04-20
GEP19971023B (en)	1997-06-13
HRP920759A2 (en)	1995-06-30
TNSN90040A1 (fr)	1991-03-05
JPH0725761B2 (ja)	1995-03-22
CA2013324C (fr)	2001-08-21
AU630178B2 (en)	1992-10-22
HU901898D0 (en)	1990-08-28
IE901157L (en)	1990-09-30

Legal Events

Date	Code	Title	Description
2004-12-27	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
NO901430L (no)	1990-10-01	Fremgangsmaate til fremstilling av 4(3h)-pteridioner, og medikamenter inneholdende slike.
NO862899D0 (no)	1986-07-18	Granulert tilsetningsmiddel for vaskemidler, fremgangsmaate for fremstilling av dette og anvendelse av dette.
NO902204L (no)	1990-11-20	Fremgangsmaate for fremstilling av pulverisert polydekstrose hovesakelig fri for syrer, og blandinger som inneholderdenne.
NO893826L (no)	1990-03-28	Fremgangsmaate for fremstilling av 2'-halomethyliden, 2'-ethenyliden og 2'-ethenyladenosinderivater.
NO882940D0 (no)	1988-07-01	Fremgangsmaate for fremstilling av castanosperminestere og glycosider.
NO893548L (no)	1990-03-07	Fremgangsmaate til fremstilling av fluorsubstituerte 4'-demetylepipodofyllotoksinglukosider.
NO882126D0 (no)	1988-05-16	Fremgangsmaate til fremstilling av nitrogenholdige derivater av epipodofyllotoksinglukosider.
DK187989D0 (da)	1989-04-19	Substituerede propanaminer, fremgangsmaade til fremstilling heraf og laegemidler indeholdende saadanne forbindelser
NO903347D0 (no)	1990-07-27	Fremgangsmaate for fremstilling av 14,17alfa-ethano- og ethanooestratriener.
NO881713D0 (no)	1988-04-20	Fremgangsmaate for fremstilling av di-t-butylfenyl-alkyl og benzylethere.
NO162992C (no)	1990-03-21	Prosess for fremstilling av roere og blandingsanordning for fremstillingen av roeren.
NO891574D0 (no)	1989-04-18	Fremgangsmaate for fremstilling av farmasoeytisk anvendbareforbindelser.
NO824108L (no)	1983-06-09	Katalysatorblanding og fremgangsmaate til fremstilling av 1,2-dikloretan.
NO911543L (no)	1991-10-21	Katalysatorsystem og fremgangsmaate for fremstilling av 1,2-diklorethan.
NO905543L (no)	1991-06-28	Fremgangsmaate for fremstilling og anvendelse av aminopyridinylmetanoler og aminometylpyridinaminer.
NO894516D0 (no)	1989-11-13	Fremgangsmaate for fremstilling av 1-aminoalkyl-3-oksosubstituert-4-aryl-1,3,4,5-tetrahydro-2h-1,3-benzodiazepin-2-on, og deres anvendelse som medikamenter.
NO891880D0 (no)	1989-05-09	Sondenaering og framgangsmaate for framstilling av slik.
NO874617D0 (no)	1987-11-05	Fremgangsmaate til fremstilling av 2,6-diamino-3-halogenobenzylpyridiner.
NO885088D0 (no)	1988-11-15	Omslagsmateriale, fremgangsmte for dets fremstilling og fremgangsmte til bruk av materialet.
NO885406D0 (no)	1988-12-06	Fremgangsmaate for fremstilling av 4-heteroaryl-1,3-benzodiazepiner og 2-substituerte-alfa-(hetero-aryl)benzenetanaminer og anvendelse derav som medikamenter.
NO900219L (no)	1990-07-18	Dihydroksybenzofenon-oksim, samt fremgangsmaate for fremstilling av slike oksimer.
NO901732L (no)	1990-10-22	Fremgangsmaate for fremstilling av 4-alkoksyalkyl-4-aminofenylpiperidiner og derivater derav.
NO891987D0 (no)	1989-05-18	Fremgangsmaate for fremstilling av n-substituerte fenyltioaniliner, fenylsulfinylaniliner og fenylsulfonylaniliner.
NO875465D0 (no)	1987-12-29	Fremgangsmaate for fremstilling av aminoalkanoyl-dibenzo(d,g)(1,3,6)dioxazociner.
NO901892L (no)	1990-10-29	Fremgangsmaate for fremstilling av (2,1-c)(1,3)-benzodiazepiner og deres anvendelse som medikamenter.