NO892821L - Fremgangsmaate for fremstilling av o2, 2'-anhydro-1-(b-d-arabinofuranosyl) tymin. - Google Patents
Fremgangsmaate for fremstilling av o2, 2'-anhydro-1-(b-d-arabinofuranosyl) tymin.Info
- Publication number
- NO892821L NO892821L NO89892821A NO892821A NO892821L NO 892821 L NO892821 L NO 892821L NO 89892821 A NO89892821 A NO 89892821A NO 892821 A NO892821 A NO 892821A NO 892821 L NO892821 L NO 892821L
- Authority
- NO
- Norway
- Prior art keywords
- arabinofuranosyl
- anhydro
- thymin
- procedure
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/09—Pyrimidine radicals with arabinosyl as the saccharide radical
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/217,906 US5008384A (en) | 1988-07-12 | 1988-07-12 | Process for the production of O.sup. 2,2'-anhydro-1-(β-D-arabinofuranosyl)thymine |
Publications (2)
Publication Number | Publication Date |
---|---|
NO892821D0 NO892821D0 (no) | 1989-07-07 |
NO892821L true NO892821L (no) | 1990-01-15 |
Family
ID=22812966
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO89892821A NO892821L (no) | 1988-07-12 | 1989-07-07 | Fremgangsmaate for fremstilling av o2, 2'-anhydro-1-(b-d-arabinofuranosyl) tymin. |
Country Status (21)
Country | Link |
---|---|
US (1) | US5008384A (de) |
EP (1) | EP0351126B1 (de) |
JP (1) | JPH075626B2 (de) |
KR (1) | KR910008112B1 (de) |
CN (1) | CN1039423A (de) |
AT (1) | ATE117314T1 (de) |
AU (1) | AU603042B2 (de) |
CA (1) | CA1315776C (de) |
DD (2) | DD284024A5 (de) |
DE (1) | DE68920648T2 (de) |
DK (1) | DK342189A (de) |
ES (1) | ES2066853T3 (de) |
FI (1) | FI893364A (de) |
GR (1) | GR3015293T3 (de) |
HU (1) | HUT50843A (de) |
IE (1) | IE65735B1 (de) |
IL (1) | IL90884A0 (de) |
NO (1) | NO892821L (de) |
PT (1) | PT91113B (de) |
YU (1) | YU138789A (de) |
ZA (1) | ZA895259B (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3065350B2 (ja) * | 1990-11-30 | 2000-07-17 | ヤマサ醤油株式会社 | 1―(2,3―ジデオキシ―β―D―グリセロ―ペント―2―エノフラノシル)チミンの製造法 |
US5596087A (en) * | 1994-05-20 | 1997-01-21 | Council Of Scientific & Industrial Research | Process for the preparation of beta thymidine |
CN100368422C (zh) | 2000-11-29 | 2008-02-13 | 三井化学株式会社 | L-核酸衍生物及其合成方法 |
WO2002079213A1 (en) * | 2001-03-30 | 2002-10-10 | Triangle Pharmaceuticals, Inc. | Process for the preparation of 2'-halo-$g(b)-l-arabinofuranosyl nucleosides |
DE10216426A1 (de) * | 2002-04-12 | 2003-10-23 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung von beta-L-2'Deoxy-Thymidin |
KR20060015542A (ko) | 2003-04-28 | 2006-02-17 | 이데닉스 (케이만) 리미티드 | 산업 규모의 뉴클레오시드 합성 |
JP2007527396A (ja) | 2003-06-30 | 2007-09-27 | イデニクス(ケイマン)リミテツド | β−L−2’−デオキシヌクレオシドの合成 |
EP2007784A2 (de) | 2006-03-15 | 2008-12-31 | Novartis AG | Verfahren zur herstellung von l-nukleinsäurederivaten und zwischenprodukte davon |
CA2729613C (en) | 2008-03-03 | 2017-02-07 | Tosk, Incorporated | Methotrexate adjuvants to reduce toxicity and methods for using the same |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3322747A (en) * | 1965-04-01 | 1967-05-30 | Merck & Co Inc | Thionocarbonate nucleosides |
US3463850A (en) * | 1967-01-03 | 1969-08-26 | Merck & Co Inc | Arabinofuranosyl 2-thiopyrimidines and pharmaceutical compositions thereof |
US3658788A (en) * | 1969-06-06 | 1972-04-25 | Salk Inst For Biological Studi | Aminooxazolines and products thereof and processes for synthesizing same |
US3812098A (en) * | 1970-03-19 | 1974-05-21 | Syntex Inc | O2,2'-anhydro-1-(beta-d-arabinofuranosyl)-cytosine derivatives and methods of making and related procedures |
US3792040A (en) * | 1970-03-19 | 1974-02-12 | Syntex Corp | Acyl derivatives of o2,2'-anhydro-1-(beta-d-arabinofuranosyl)-cytosines and methods of preparing |
US3709874A (en) * | 1970-03-19 | 1973-01-09 | Syntex Corp | 1-beta-d-arabinofuranosyl cytosine derivatives and methods of preparing |
US3920630A (en) * | 1970-09-24 | 1975-11-18 | Upjohn Co | 2,2{40 -Anhydro-ara-cytidine compounds and process of preparation |
SE391183B (sv) * | 1971-04-15 | 1977-02-07 | Asahi Chemical Ind | 2',3'-0-sulfinylcytidin och syraadditionssalter derav till anvendning som mellanprodukt for framstellning av 2,2'-anhydro-(1-beta-d-arabinofuranosyl) cytosin |
US3978042A (en) * | 1975-01-31 | 1976-08-31 | The Upjohn Company | Process for preparing cyclocytidine derivatives |
US4140850A (en) * | 1977-08-29 | 1979-02-20 | The Upjohn Company | 2,2'-Anhydrotriazine nucleosides and process for preparing the same |
JPS5649398A (en) * | 1979-09-28 | 1981-05-02 | Yamasa Shoyu Co Ltd | Preparation of 1-beta-d-arabinofuranosyl-2,2'-cyclothymine |
JPS636557A (ja) * | 1986-06-26 | 1988-01-12 | Sharp Corp | 微細パタ−ン形成方法 |
-
1988
- 1988-07-12 US US07/217,906 patent/US5008384A/en not_active Expired - Lifetime
-
1989
- 1989-07-05 DE DE68920648T patent/DE68920648T2/de not_active Expired - Fee Related
- 1989-07-05 AT AT89306820T patent/ATE117314T1/de not_active IP Right Cessation
- 1989-07-05 ES ES89306820T patent/ES2066853T3/es not_active Expired - Lifetime
- 1989-07-05 IL IL90884A patent/IL90884A0/xx unknown
- 1989-07-05 EP EP89306820A patent/EP0351126B1/de not_active Expired - Lifetime
- 1989-07-07 NO NO89892821A patent/NO892821L/no unknown
- 1989-07-10 CA CA000605243A patent/CA1315776C/en not_active Expired - Fee Related
- 1989-07-10 CN CN89104789A patent/CN1039423A/zh active Pending
- 1989-07-10 PT PT91113A patent/PT91113B/pt not_active IP Right Cessation
- 1989-07-10 JP JP1177876A patent/JPH075626B2/ja not_active Expired - Fee Related
- 1989-07-11 YU YU01387/89A patent/YU138789A/xx unknown
- 1989-07-11 IE IE223389A patent/IE65735B1/en not_active IP Right Cessation
- 1989-07-11 DD DD89330684A patent/DD284024A5/de not_active IP Right Cessation
- 1989-07-11 ZA ZA895259A patent/ZA895259B/xx unknown
- 1989-07-11 DK DK342189A patent/DK342189A/da not_active Application Discontinuation
- 1989-07-11 KR KR1019890009853A patent/KR910008112B1/ko active IP Right Grant
- 1989-07-11 DD DD89337873A patent/DD292003A5/de not_active IP Right Cessation
- 1989-07-11 HU HU893491A patent/HUT50843A/hu unknown
- 1989-07-11 FI FI893364A patent/FI893364A/fi not_active Application Discontinuation
- 1989-07-11 AU AU38020/89A patent/AU603042B2/en not_active Ceased
-
1995
- 1995-03-03 GR GR950400471T patent/GR3015293T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DD292003A5 (de) | 1991-07-18 |
IL90884A0 (en) | 1990-02-09 |
KR910008112B1 (ko) | 1991-10-10 |
DD284024A5 (de) | 1990-10-31 |
NO892821D0 (no) | 1989-07-07 |
ATE117314T1 (de) | 1995-02-15 |
KR900001704A (ko) | 1990-02-27 |
GR3015293T3 (en) | 1995-06-30 |
DE68920648D1 (de) | 1995-03-02 |
JPH0259598A (ja) | 1990-02-28 |
HUT50843A (en) | 1990-03-28 |
DE68920648T2 (de) | 1995-05-18 |
IE65735B1 (en) | 1995-11-15 |
ES2066853T3 (es) | 1995-03-16 |
FI893364A0 (fi) | 1989-07-11 |
DK342189D0 (da) | 1989-07-11 |
FI893364A (fi) | 1990-01-13 |
AU603042B2 (en) | 1990-11-01 |
PT91113B (pt) | 1995-01-31 |
ZA895259B (en) | 1991-02-27 |
EP0351126A3 (en) | 1990-10-24 |
CN1039423A (zh) | 1990-02-07 |
EP0351126A2 (de) | 1990-01-17 |
EP0351126B1 (de) | 1995-01-18 |
YU138789A (en) | 1990-12-31 |
DK342189A (da) | 1990-01-15 |
JPH075626B2 (ja) | 1995-01-25 |
IE892233L (en) | 1990-01-12 |
US5008384A (en) | 1991-04-16 |
PT91113A (pt) | 1990-02-08 |
CA1315776C (en) | 1993-04-06 |
AU3802089A (en) | 1990-04-26 |
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