NO874749L - N9-cyklopentyl-substituerte adeninderivater. - Google Patents
N9-cyklopentyl-substituerte adeninderivater.Info
- Publication number
- NO874749L NO874749L NO874749A NO874749A NO874749L NO 874749 L NO874749 L NO 874749L NO 874749 A NO874749 A NO 874749A NO 874749 A NO874749 A NO 874749A NO 874749 L NO874749 L NO 874749L
- Authority
- NO
- Norway
- Prior art keywords
- adenin
- cyclopentyl
- derivatives
- substituted
- substituted adenin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D303/46—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by amide or nitrile radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US93132786A | 1986-11-14 | 1986-11-14 |
Publications (4)
Publication Number | Publication Date |
---|---|
NO874749D0 NO874749D0 (no) | 1987-11-13 |
NO874749L true NO874749L (no) | 1988-05-16 |
NO166184B NO166184B (no) | 1991-03-04 |
NO166184C NO166184C (no) | 1991-06-12 |
Family
ID=25460605
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO874749A NO166184C (no) | 1986-11-14 | 1987-11-13 | Analogifremgangsmaate for fremstilling av terapeutisk aktive n9-cyklopentyl-substituerte adeninderivater. |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0267878A1 (no) |
JP (1) | JPS63135384A (no) |
KR (1) | KR880006241A (no) |
AU (1) | AU608258B2 (no) |
CA (1) | CA1288431C (no) |
DD (1) | DD273833A5 (no) |
DK (1) | DK596087A (no) |
FI (1) | FI874982A (no) |
HU (1) | HU198489B (no) |
IL (1) | IL84414A0 (no) |
NO (1) | NO166184C (no) |
NZ (1) | NZ222527A (no) |
PH (1) | PH25044A (no) |
PT (1) | PT86120B (no) |
ZA (1) | ZA878527B (no) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN164556B (no) * | 1986-03-06 | 1989-04-08 | Takeda Chemical Industries Ltd | |
US5063233A (en) * | 1986-11-14 | 1991-11-05 | Ciba-Geigy Corporation | N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists |
US5015739A (en) * | 1988-04-22 | 1991-05-14 | Schering Corporation | Processes for preparation of cyclopentyl purine derivatives |
GB8813148D0 (en) * | 1988-06-03 | 1988-07-06 | Glaxo Group Ltd | Chemical compounds |
US5216141A (en) * | 1988-06-06 | 1993-06-01 | Benner Steven A | Oligonucleotide analogs containing sulfur linkages |
HU204843B (en) * | 1988-09-27 | 1992-02-28 | Merrell Dow Pharma | Process for producing 2'-halogen-methylidene adenosine derivatives and pharmaceutical compositions comprising same |
GB8826205D0 (en) * | 1988-11-09 | 1988-12-14 | Wellcome Found | Heterocyclic compounds |
US5312961A (en) * | 1989-02-14 | 1994-05-17 | Elf Sanofi | 2-amino-7-hydroxytetralin carboxylalkyl ethers |
GB8916478D0 (en) * | 1989-07-19 | 1989-09-06 | Glaxo Group Ltd | Chemical process |
GB8916479D0 (en) * | 1989-07-19 | 1989-09-06 | Glaxo Group Ltd | Chemical process |
GB8926417D0 (en) * | 1989-11-22 | 1990-01-10 | Wellcome Found | Heterocyclic compounds |
US5514688A (en) * | 1990-09-14 | 1996-05-07 | Merrell Dow Pharmaceuticals Inc. | Carbocyclic adenosine analogs useful as immunosuppressants |
US5470857A (en) * | 1990-09-14 | 1995-11-28 | Marion Merrell Dow Inc. | Carbocyclic nucleoside analogs useful as immunosuppressants |
US5561134A (en) * | 1990-09-25 | 1996-10-01 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties |
GB9108376D0 (en) * | 1991-04-19 | 1991-06-05 | Enzymatix Ltd | Cyclopentenes |
US5206222A (en) * | 1991-05-22 | 1993-04-27 | Vanderbilt University | Methods for the reduction of myocardial reperfusion injury |
US5817672A (en) * | 1991-12-06 | 1998-10-06 | Hoechst Marion Roussel, Inc. | Trans cyclopentanyl purine analogs useful as immunosuppressants |
US5723466A (en) * | 1991-12-06 | 1998-03-03 | Hoechst Marion Roussel, Inc. | Trans cyclopentanyl purine analogs useful as immunosuppressants |
US5817660A (en) * | 1991-12-06 | 1998-10-06 | Hoechst Marion Roussel, Inc. | Trans cyclopentanyl purine analogs useful as immunosuppressants |
US5817661A (en) * | 1991-12-06 | 1998-10-06 | Hoechst Marion Roussel, Inc. | Trans cyclopentanyl purine analogs useful as immunosuppressants |
FR2685918B1 (fr) * | 1992-01-08 | 1995-06-23 | Union Pharma Scient Appl | Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant. |
US5840923A (en) * | 1992-04-21 | 1998-11-24 | Chiroscience Limited | Chiral cyclopentene derivatives and their preparation |
EP0638077B1 (en) * | 1992-04-21 | 2001-09-19 | Chirotech Technology Limited | Chiral cyclopentene derivatives and their preparation |
IT1254915B (it) * | 1992-04-24 | 1995-10-11 | Gloria Cristalli | Derivati di adenosina ad attivita' a2 agonista |
EP0577558A2 (de) * | 1992-07-01 | 1994-01-05 | Ciba-Geigy Ag | Carbocyclische Nukleoside mit bicyclischen Ringen, Oligonukleotide daraus, Verfahren zu deren Herstellung, deren Verwendung und Zwischenproduckte |
GB9414208D0 (en) * | 1994-07-14 | 1994-08-31 | Glaxo Group Ltd | Compounds |
WO1996019478A1 (en) * | 1994-12-19 | 1996-06-27 | Novartis Ag | 6'-substituted carbocyclic nucleosides |
AU4343500A (en) | 1999-04-16 | 2000-11-02 | Schering Corporation | Use of azetidinone compounds |
WO2001060383A1 (en) * | 2000-02-18 | 2001-08-23 | Southern Research Institute | METHODS FOR SYNTHESIZING 2-CHLORO-9-(2-DEOXY-2-FLUORO-β-D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE |
US20050033044A1 (en) | 2003-05-19 | 2005-02-10 | Bristol-Myers Squibb Pharma Company | Methods for preparing 2-alkynyladenosine derivatives |
GT200500281A (es) | 2004-10-22 | 2006-04-24 | Novartis Ag | Compuestos organicos. |
GB0500785D0 (en) * | 2005-01-14 | 2005-02-23 | Novartis Ag | Organic compounds |
GB0607950D0 (en) | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
PL2013211T3 (pl) | 2006-04-21 | 2012-08-31 | Novartis Ag | Pochodne puryny do zastosowania jako agoniści receptora adenozyny A2A |
EP1889846A1 (en) | 2006-07-13 | 2008-02-20 | Novartis AG | Purine derivatives as A2a agonists |
EP1903044A1 (en) | 2006-09-14 | 2008-03-26 | Novartis AG | Adenosine Derivatives as A2A Receptor Agonists |
JP6163105B2 (ja) * | 2010-11-16 | 2017-07-12 | ユニバーシティー オブ サザン カリフォルニア | 体性幹細胞の非対称***を促進するためのcbp/カテニン拮抗剤 |
CN105061431B (zh) * | 2015-07-28 | 2017-03-29 | 山东百诺医药股份有限公司 | 6‑n‑(2‑(甲硫基)乙基)‑2‑((3,3,3‑三氟丙基)硫代)‑9h‑嘌呤及其制备方法和应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2610985A1 (de) * | 1976-03-16 | 1977-09-29 | Byk Gulden Lomberg Chem Fab | Arzneimittel enthaltend beta-d-1 (6-amino-9h-purin-9-yl)-1-deoxyribofuranuronsaeurederivate |
US4345984A (en) * | 1981-03-02 | 1982-08-24 | The Procter & Gamble Company | Novel prostaglandin analogues and process for making same |
US4543255A (en) * | 1984-05-10 | 1985-09-24 | Southern Research Institute | Carbocyclic analogs of purine 2'-deoxyribofuranosides |
US4742064A (en) * | 1985-09-10 | 1988-05-03 | Regents Of The University Of Minnesota | Antiviral carbocyclic analogs of xylofuranosylpurines |
-
1987
- 1987-11-09 IL IL84414A patent/IL84414A0/xx unknown
- 1987-11-09 EP EP87810647A patent/EP0267878A1/en not_active Withdrawn
- 1987-11-11 FI FI874982A patent/FI874982A/fi not_active IP Right Cessation
- 1987-11-12 NZ NZ222527A patent/NZ222527A/xx unknown
- 1987-11-12 PT PT86120A patent/PT86120B/pt not_active IP Right Cessation
- 1987-11-12 DD DD87308972A patent/DD273833A5/de not_active IP Right Cessation
- 1987-11-12 CA CA000551656A patent/CA1288431C/en not_active Expired - Lifetime
- 1987-11-13 JP JP62285628A patent/JPS63135384A/ja active Pending
- 1987-11-13 DK DK596087A patent/DK596087A/da not_active Application Discontinuation
- 1987-11-13 AU AU81193/87A patent/AU608258B2/en not_active Ceased
- 1987-11-13 NO NO874749A patent/NO166184C/no unknown
- 1987-11-13 PH PH36065A patent/PH25044A/en unknown
- 1987-11-13 ZA ZA878527A patent/ZA878527B/xx unknown
- 1987-11-13 HU HU875070A patent/HU198489B/hu unknown
- 1987-11-23 KR KR870012780A patent/KR880006241A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
HU198489B (en) | 1989-10-30 |
DD273833A5 (de) | 1989-11-29 |
NO166184C (no) | 1991-06-12 |
NO166184B (no) | 1991-03-04 |
AU608258B2 (en) | 1991-03-28 |
CA1288431C (en) | 1991-09-03 |
AU8119387A (en) | 1988-05-19 |
PH25044A (en) | 1991-01-28 |
NZ222527A (en) | 1990-08-28 |
EP0267878A1 (en) | 1988-05-18 |
KR880006241A (ko) | 1988-07-22 |
HUT45057A (en) | 1988-05-30 |
FI874982A0 (fi) | 1987-11-11 |
PT86120A (en) | 1987-12-01 |
ZA878527B (en) | 1988-05-16 |
JPS63135384A (ja) | 1988-06-07 |
DK596087D0 (da) | 1987-11-13 |
DK596087A (da) | 1988-05-15 |
FI874982A (fi) | 1988-05-15 |
NO874749D0 (no) | 1987-11-13 |
IL84414A0 (en) | 1988-04-29 |
PT86120B (pt) | 1990-08-31 |
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