NO794181L - Fremgangsmaate for fremstilling av merkaptoacetyl-prolin- og pipekolsyre-derivater - Google Patents

Fremgangsmaate for fremstilling av merkaptoacetyl-prolin- og pipekolsyre-derivater

Info

Publication number
NO794181L
NO794181L NO794181A NO794181A NO794181L NO 794181 L NO794181 L NO 794181L NO 794181 A NO794181 A NO 794181A NO 794181 A NO794181 A NO 794181A NO 794181 L NO794181 L NO 794181L
Authority
NO
Norway
Prior art keywords
capacetyl
prolinic
brand
procedure
preparation
Prior art date
Application number
NO794181A
Other languages
English (en)
Other versions
NO153569C (no
NO153569B (no
Inventor
John Krapcho
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of NO794181L publication Critical patent/NO794181L/no
Publication of NO153569B publication Critical patent/NO153569B/no
Publication of NO153569C publication Critical patent/NO153569C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D497/00Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D497/02Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D497/10Spiro-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
NO794181A 1978-12-22 1979-12-19 Analogifremgangsmaate for fremstilling av terapeutisk aktive merkaptoacetyl-prolin-derivater. NO153569C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US97231478A 1978-12-22 1978-12-22

Publications (3)

Publication Number Publication Date
NO794181L true NO794181L (no) 1980-06-24
NO153569B NO153569B (no) 1986-01-06
NO153569C NO153569C (no) 1986-05-21

Family

ID=25519507

Family Applications (1)

Application Number Title Priority Date Filing Date
NO794181A NO153569C (no) 1978-12-22 1979-12-19 Analogifremgangsmaate for fremstilling av terapeutisk aktive merkaptoacetyl-prolin-derivater.

Country Status (31)

Country Link
JP (1) JPS5594357A (no)
AT (1) AT374174B (no)
AU (1) AU533149B2 (no)
BE (1) BE880815A (no)
CA (1) CA1132985A (no)
CH (1) CH642065A5 (no)
CS (1) CS215036B2 (no)
DD (1) DD148338A5 (no)
DE (1) DE2951200A1 (no)
DK (1) DK159115C (no)
ES (2) ES487180A0 (no)
FI (1) FI70886C (no)
FR (1) FR2444669A1 (no)
GB (1) GB2039478B (no)
GR (1) GR78384B (no)
HK (1) HK15684A (no)
HU (1) HU179644B (no)
IE (1) IE49321B1 (no)
IL (1) IL58930A (no)
IT (1) IT1126841B (no)
LU (1) LU82023A1 (no)
NL (1) NL7909246A (no)
NO (1) NO153569C (no)
NZ (1) NZ192449A (no)
PH (1) PH19213A (no)
PL (1) PL133414B1 (no)
PT (1) PT70620A (no)
SE (1) SE451839B (no)
SU (1) SU1115668A3 (no)
YU (1) YU314879A (no)
ZA (1) ZA796720B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2455585A1 (fr) * 1979-05-04 1980-11-28 Ono Pharmaceutical Co Derives d'oxoaminoacides, procede de fabrication et composition pharmaceutique
US4288368A (en) * 1979-07-30 1981-09-08 E. R. Squibb & Sons, Inc. Dithioacylproline derivatives
US4291040A (en) * 1979-10-22 1981-09-22 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of 4-disubstituted prolines and 4-substituted dehydroprolines
US4356182A (en) * 1979-10-22 1982-10-26 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of 4-disubstituted prolines
HU184082B (en) * 1979-12-29 1984-06-28 Egyt Gyogyszervegyeszeti Gyar Process for preparing 1-3-/3mercapto-/2s/-methyl-propinyl/-pyrrolidine-/2s/-carboxylic acid
US4284624A (en) 1980-05-02 1981-08-18 E. R. Squibb & Sons, Inc. Mixed disulfides
US4316905A (en) * 1980-07-01 1982-02-23 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of various 4-substituted prolines
US4311705A (en) * 1980-10-06 1982-01-19 E. R. Squibb & Sons, Inc. Carboxyalkanoyl and hydroxycarbamoylalkanoyl derivatives of substituted prolines
US4462943A (en) * 1980-11-24 1984-07-31 E. R. Squibb & Sons, Inc. Carboxyalkyl amino acid derivatives of various substituted prolines
US4416831A (en) 1981-04-27 1983-11-22 E. R. Squibb & Sons, Inc. Amino and substituted amino phosphinylalkanoyl compounds
US4374131A (en) 1981-04-27 1983-02-15 E. R. Squibb & Sons, Inc. Amino and substituted amino phosphinyl-alkanoyl compounds
US4381297A (en) 1981-05-04 1983-04-26 E. R. Squibb & Sons, Inc. Substituted carbonyl phosphinyl-alkanoyl compounds
US4416833A (en) 1981-05-04 1983-11-22 E. R. Squibb & Sons, Inc. Substituted carbonyl phosphinyl-alkanoyl compounds
US4555506A (en) * 1981-12-24 1985-11-26 E. R. Squibb & Sons, Inc. Phosphorus containing compounds and use as hypotensives
US4452791A (en) * 1982-03-15 1984-06-05 E. R. Squibb & Sons, Inc. Aminoalkyl and related substituted phosphinic acid angiotensin converting enzyme inhibitors
US4560680A (en) * 1982-03-15 1985-12-24 E. R. Squibb & Sons, Inc. Aminoalkyl and related substituted phosphinic acid angiotensin converting enzyme inhibitors
CA1258853A (en) * 1982-04-30 1989-08-29 Rudiger D. Haugwitz Substituted 4-phenoxy prolines
US4703043A (en) * 1982-06-23 1987-10-27 E. R. Squibb & Sons, Inc. Phosphonyl hydroxyacyl amino acid derivatives as antihypertensive
US4452790A (en) * 1982-06-23 1984-06-05 E. R. Squibb & Sons, Inc. Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives
US4616005A (en) * 1982-06-23 1986-10-07 E. R. Squibb & Sons, Inc. Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives
US4567166A (en) * 1982-07-14 1986-01-28 E. R. Squibb & Sons, Inc. Amino and substituted amino phosphinylalkanoyl compounds useful for treating hypertension
US4709046A (en) * 1983-05-09 1987-11-24 E. R. Squibb & Sons, Inc. Acylmercaptoalkanoyl and mercaptoalkanoyl spiro compounds
AU632596B2 (en) * 1989-08-21 1993-01-07 E.R. Squibb & Sons, Inc. Phosphonate substituted amino or imino acids useful as antihypertensives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4046889A (en) * 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives
US4091024A (en) * 1976-12-03 1978-05-23 E. R. Squibb & Sons, Inc. Pyrrolidine and piperidine-2-carboxylic acid derivatives
IT7851510A0 (it) * 1977-10-28 1978-10-16 Sandoz Ag Ammidi di amminoacidi ciclici loro preparazione e loro applicazione quali medicamenti
PH15381A (en) * 1978-02-21 1982-12-17 Squibb & Sons Inc Halogen substituted mercaptoacylamino acids
CA1144930A (en) * 1978-08-11 1983-04-19 Miguel A. Ondetti Mercaptoacyl derivatives of substituted prolines

Also Published As

Publication number Publication date
DE2951200A1 (de) 1980-07-10
ES8103039A1 (es) 1981-02-16
FR2444669A1 (fr) 1980-07-18
GB2039478A (en) 1980-08-13
PH19213A (en) 1986-02-04
FI70886C (fi) 1986-10-27
ATA805479A (de) 1983-08-15
AU533149B2 (en) 1983-11-03
JPS5594357A (en) 1980-07-17
SE451839B (sv) 1987-11-02
BE880815A (fr) 1980-06-23
HK15684A (en) 1984-03-02
NL7909246A (nl) 1980-06-24
CH642065A5 (de) 1984-03-30
NO153569C (no) 1986-05-21
DK550079A (da) 1980-06-23
AU5371479A (en) 1980-06-26
LU82023A1 (de) 1980-04-23
SE7910550L (sv) 1980-06-23
PL220609A1 (no) 1980-12-01
AT374174B (de) 1984-03-26
ES8102094A1 (es) 1980-12-16
PL133414B1 (en) 1985-05-31
IE49321B1 (en) 1985-09-18
DK159115C (da) 1991-02-11
CS215036B2 (en) 1982-06-25
DK159115B (da) 1990-09-03
FR2444669B1 (no) 1983-06-03
IL58930A (en) 1983-07-31
GR78384B (no) 1984-09-26
ES488752A0 (es) 1981-02-16
FI794027A (fi) 1980-06-23
YU314879A (en) 1983-04-30
IE792468L (en) 1980-06-22
NZ192449A (en) 1984-05-31
ES487180A0 (es) 1980-12-16
CA1132985A (en) 1982-10-05
IT7951167A0 (it) 1979-12-21
FI70886B (fi) 1986-07-18
NO153569B (no) 1986-01-06
HU179644B (en) 1982-11-29
ZA796720B (en) 1980-11-26
PT70620A (en) 1980-01-01
GB2039478B (en) 1983-02-16
IT1126841B (it) 1986-05-21
IL58930A0 (en) 1980-03-31
DD148338A5 (de) 1981-05-20
SU1115668A3 (ru) 1984-09-23

Similar Documents

Publication Publication Date Title
NO794181L (no) Fremgangsmaate for fremstilling av merkaptoacetyl-prolin- og pipekolsyre-derivater
NO790358L (no) Fremgangsmaate for fremstilling av alkylendiaminderivater
NO820287L (no) Fremgangsmaate for fremstilling av isocyanursyre-derivater
NO790865L (no) Derivater av jodpropargyl samt fremgangsmaate til fremstilling av samme
NO794010L (no) Fremgangsmaate ved fremstilling av aminosyrederivater
NO148925C (no) Analogifremgangsmaate til fremstilling av 5-metyl-isoksazol-4-karboksylsyre-(4-trifluormetyl)-anilid med antiflogistisk og antireumatisk virkning
FI792863A (fi) Foerfarande foer igaongsaettning av aongpanna med tvaongscirkulation
NO150879C (no) Fremgangsmaate for fremstilling av d-camforat av l-carnitinamid og d-camforat av d-carnitinamid
NO792404L (no) Fremgangsmaate for fremstilling av imidazolderivater
NO151201C (no) Fremgangsmaate for fremstilling av terapeutisk virksomme antigenderivater
NO801046L (no) Penem-3-karboksylsyrederivater og fremgangsmaate til fremstilling av samme
NO151895C (no) Fremgangsmaate for fremstilling av pyrido-indolderivater
NO790543L (no) Fremgangsmaate ved fremstilling av smaksstoff for naeringsmidler
NO792139L (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive tiazoloksamsyre-derivater
NO791139L (no) Fremgangsmaate for fremstilling av lysergolderivater
FI791562A (fi) Foerfarande foer framstaellning av 4-amino-2-piperidinokinazolinderivat
NO151619C (no) Fremgangsmaate for fremstilling av cyklopropan-karboksylsyreester-derivater
DK209879A (da) Fremgangsmaade til fremstilling af aryleddikesyrederivater nellemprodukter hertil og disses fremstilling
NO147310C (no) Fremgangsmaate for fremstilling av substituerte antitumorantracykliner
NO793164L (no) Fremgangsmaate for fremstilling av natriumamoksycillan
NO802435L (no) Fremgangsmaate til fremstilling av tetrahydrokinolinderivater
NO152254C (no) Fremgangsmaate til fremstilling av karbazolderivater
NO794090L (no) Fremgangsmaate for fremstilling av klordioksyd
NO791349L (no) Fenoksyalkyl-trialkoksysilaner og fremgangsmaate til fremstilling av disse
SE434743B (sv) Forfarande for framstellning av (2-pyrimidinyl-tio)-alkansyraamider