NO331017B1 - Glukan, adjuvanssammensetning omfattende glukanet samt anvendelse av glukanet for fremstilling av en mukosal administrerbar adjuvanssammensetning. - Google Patents

Glukan, adjuvanssammensetning omfattende glukanet samt anvendelse av glukanet for fremstilling av en mukosal administrerbar adjuvanssammensetning.

Info

Publication number
NO331017B1
NO331017B1 NO20023935A NO20023935A NO331017B1 NO 331017 B1 NO331017 B1 NO 331017B1 NO 20023935 A NO20023935 A NO 20023935A NO 20023935 A NO20023935 A NO 20023935A NO 331017 B1 NO331017 B1 NO 331017B1
Authority
NO
Norway
Prior art keywords
glucan
adjuvant composition
preparation
well
mucosally administrable
Prior art date
Application number
NO20023935A
Other languages
English (en)
Other versions
NO20023935D0 (no
NO20023935L (no
Inventor
Bjorn Haneberg
Jan Raa
Aud Kathrine Herland Berstad
Hilde Bakke
Inger Lise Haugen
Johan Holst
Liba Janakova
Gro Ellen Korsvold
Fredrik Oftung
Original Assignee
Biotec Pharmacon Asa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotec Pharmacon Asa filed Critical Biotec Pharmacon Asa
Publication of NO20023935D0 publication Critical patent/NO20023935D0/no
Publication of NO20023935L publication Critical patent/NO20023935L/no
Publication of NO331017B1 publication Critical patent/NO331017B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55583Polysaccharides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20023935A 2000-02-23 2002-08-19 Glukan, adjuvanssammensetning omfattende glukanet samt anvendelse av glukanet for fremstilling av en mukosal administrerbar adjuvanssammensetning. NO331017B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/511,582 US20020009463A1 (en) 2000-02-23 2000-02-23 Novel, non-antigenic, mucosal adjuvant formulation which enhances the effects of substances, including vaccine antigens, in contact with mucosal body surfaces
PCT/IB2001/000144 WO2001062283A2 (en) 2000-02-23 2001-02-02 Mucosal adjuvant formulation

Publications (3)

Publication Number Publication Date
NO20023935D0 NO20023935D0 (no) 2002-08-19
NO20023935L NO20023935L (no) 2002-10-15
NO331017B1 true NO331017B1 (no) 2011-09-12

Family

ID=24035524

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20023935A NO331017B1 (no) 2000-02-23 2002-08-19 Glukan, adjuvanssammensetning omfattende glukanet samt anvendelse av glukanet for fremstilling av en mukosal administrerbar adjuvanssammensetning.

Country Status (10)

Country Link
US (3) US20020009463A1 (no)
EP (1) EP1259259B1 (no)
JP (2) JP4947506B2 (no)
CN (1) CN1404399B (no)
AT (1) ATE511855T1 (no)
AU (1) AU771205B2 (no)
DK (1) DK1259259T3 (no)
ES (1) ES2369550T3 (no)
NO (1) NO331017B1 (no)
WO (1) WO2001062283A2 (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7507724B2 (en) 2001-01-16 2009-03-24 Sloan-Kettering Institute For Cancer Research Therapy-enhancing glucan
WO2003039567A1 (fr) * 2001-11-06 2003-05-15 Orient Cancer Therary Co.,Ltd. Compositions anticancereuses
KR20050044523A (ko) * 2001-11-19 2005-05-12 벡톤 디킨슨 앤드 컴퍼니 입자 형태의 약제학적 조성물
RU2378008C2 (ru) * 2002-05-14 2010-01-10 Новартис Вэксинес Энд Дайэгностикс С.Р.Л. Комбинированные вакцины против бактериального менингита для введения через слизистую оболочку
WO2006109312A2 (en) * 2005-04-15 2006-10-19 Vascular Biogenics Ltd. Compositions containing beta 2-glycoprotein i-derived peptides for the prevention and/or treatment of vascular disease
US8323644B2 (en) 2006-01-17 2012-12-04 Sloan-Kettering Institute For Cancer Research Therapy-enhancing glucan
US11316688B2 (en) 2006-12-29 2022-04-26 Kip Prod P1 Lp Multi-services application gateway and system employing the same
US8180735B2 (en) 2006-12-29 2012-05-15 Prodea Systems, Inc. Managed file backup and restore at remote storage locations through multi-services gateway at user premises
US11783925B2 (en) 2006-12-29 2023-10-10 Kip Prod P1 Lp Multi-services application gateway and system employing the same
US9602880B2 (en) 2006-12-29 2017-03-21 Kip Prod P1 Lp Display inserts, overlays, and graphical user interfaces for multimedia systems
US20170344703A1 (en) 2006-12-29 2017-11-30 Kip Prod P1 Lp Multi-services application gateway and system employing the same
US9569587B2 (en) 2006-12-29 2017-02-14 Kip Prod Pi Lp Multi-services application gateway and system employing the same
CN101244267B (zh) * 2007-02-12 2011-12-21 复旦大学 一种增强微生物疫苗免疫原性的免疫制剂
WO2008102151A1 (en) * 2007-02-21 2008-08-28 Biotec Pharmacon Asa Medical uses of glucans
JP5272129B2 (ja) * 2007-04-25 2013-08-28 幸仁 秋山 インフルエンザウイルスの不活化抗原に対するアジュバント、及び分泌型IgA抗体誘導剤
TWI496578B (zh) * 2009-10-08 2015-08-21 Aureo Co Ltd 流感病毒感染症的治療劑
US20130079299A1 (en) * 2010-05-12 2013-03-28 Glucan Corporation Arthritis Therapeutic Agent
WO2012014978A1 (ja) * 2010-07-29 2012-02-02 国立大学法人北海道大学 免疫アジュバント
EP2694030A2 (en) 2011-03-04 2014-02-12 Sana Pharma AS Cosmetic formulations
JP6306523B2 (ja) 2012-03-13 2018-04-04 ベクトン ディキンソン フランス 小型化した薬剤送出部を有する注入器具
JP7438131B2 (ja) * 2018-04-24 2024-02-26 メモリアル スローン-ケタリング キャンサー センター 経口酵母ベータグルカンを用いる低免疫原性抗原特異的ワクチンの免疫原性強化方法
CN111420044B (zh) * 2020-05-11 2021-04-09 中逸安科生物技术股份有限公司 一种四价流感病毒亚单位疫苗及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3071750D1 (en) * 1979-07-04 1986-10-16 Kureha Chemical Ind Co Ltd Nasal preparations, process for making same and their use
DE3019614A1 (de) * 1980-05-22 1981-12-03 Sankyo Co., Ltd., Tokyo Hydrolysiertes polysaccharid
EP0045718A3 (de) * 1980-07-25 1983-01-19 Ciba-Geigy Ag Nasalpräparate und Verfahren zu deren Herstellung
US4857318A (en) * 1983-11-07 1989-08-15 Syntex (U.S.A.) Inc. Bordetella bronchiseptica pilus subunit protein vaccine effective against bordetella pertussis
US4810646A (en) * 1984-11-28 1989-03-07 Massachusetts Institute Of Technology Glucan compositions and process for preparation thereof
CA1330303C (en) * 1989-02-20 1994-06-21 Libor Henry Nikl Composition and process to enhance the efficacy of a fish vaccine
US5032401A (en) * 1989-06-15 1991-07-16 Alpha Beta Technology Glucan drug delivery system and adjuvant
US5488040A (en) * 1989-09-08 1996-01-30 Alpha-Beta Technology, Inc. Use of neutral soluble glucan preparations to stimulate platelet production
US5223491A (en) * 1989-11-09 1993-06-29 Donzis Byron A Method for revitalizing skin by applying topically water insoluble glucan
CA2040374C (en) * 1990-07-06 1998-06-16 Gunnar Rorstad Process for enhancing the resistance of aquatic animals to disease
JP3522772B2 (ja) * 1991-05-21 2004-04-26 台糖株式会社 ワクチンの免疫効果増強剤
NO300692B1 (no) * 1994-04-29 1997-07-07 Biotec Mackzymal As Solubilisert forgrenet ß-1,3-glukan og anvendelse derav samt anvendelse av usolubilisert forgrenet ß-1,3-glukan
AUPN166195A0 (en) * 1995-03-13 1995-04-06 Norvet Research Pty Limited Process for glucan extraction
US5785975A (en) * 1995-06-26 1998-07-28 Research Triangle Pharmaceuticals Adjuvant compositions and vaccine formulations comprising same
CA2333750A1 (en) * 1998-06-23 1999-12-29 Dale T. Umetsu Adjuvant therapy

Also Published As

Publication number Publication date
WO2001062283A2 (en) 2001-08-30
US20020009463A1 (en) 2002-01-24
US20120014991A1 (en) 2012-01-19
AU771205B2 (en) 2004-03-18
EP1259259B1 (en) 2011-06-08
JP2011190278A (ja) 2011-09-29
JP2003523401A (ja) 2003-08-05
EP1259259A2 (en) 2002-11-27
AU4094301A (en) 2001-09-03
NO20023935D0 (no) 2002-08-19
ES2369550T3 (es) 2011-12-01
CN1404399A (zh) 2003-03-19
CN1404399B (zh) 2012-04-04
US20030104010A1 (en) 2003-06-05
ATE511855T1 (de) 2011-06-15
JP4947506B2 (ja) 2012-06-06
WO2001062283A3 (en) 2002-02-14
NO20023935L (no) 2002-10-15
DK1259259T3 (da) 2011-08-01

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