NO20093200L - Tiazolidinderivater - Google Patents
TiazolidinderivaterInfo
- Publication number
- NO20093200L NO20093200L NO20093200A NO20093200A NO20093200L NO 20093200 L NO20093200 L NO 20093200L NO 20093200 A NO20093200 A NO 20093200A NO 20093200 A NO20093200 A NO 20093200A NO 20093200 L NO20093200 L NO 20093200L
- Authority
- NO
- Norway
- Prior art keywords
- thiazolidine derivatives
- derivatives
- thiazolidine
- medicaments
- formula
- Prior art date
Links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
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- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
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- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
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- C07D513/04—Ortho-condensed systems
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Abstract
Oppfinnelsen vedrører nye tiazolidinderivater med formel (I), hvori A og R1 er som beskrevet i beskrivelsen og anvendelse derav som medikamenter, spesielt som oreksinreseptorantagonister.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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IB2007051048 | 2007-03-26 | ||
IB2008050620 | 2008-02-21 | ||
PCT/IB2008/051110 WO2008117241A2 (en) | 2007-03-26 | 2008-03-25 | Thiazolidine derivatives as orexin receptor antagonists |
Publications (1)
Publication Number | Publication Date |
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NO20093200L true NO20093200L (no) | 2009-10-23 |
Family
ID=39789108
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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NO20093200A NO20093200L (no) | 2007-03-26 | 2009-10-23 | Tiazolidinderivater |
Country Status (17)
Country | Link |
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US (1) | US8236964B2 (no) |
EP (1) | EP2125760A2 (no) |
JP (1) | JP2010522737A (no) |
KR (1) | KR20090125195A (no) |
CN (1) | CN101641342B (no) |
AR (1) | AR065822A1 (no) |
AU (1) | AU2008231441A1 (no) |
BR (1) | BRPI0808504A2 (no) |
CA (1) | CA2677991A1 (no) |
CL (1) | CL2008000836A1 (no) |
IL (1) | IL201112A0 (no) |
MA (1) | MA31289B1 (no) |
MX (1) | MX2009009690A (no) |
NO (1) | NO20093200L (no) |
RU (1) | RU2009139285A (no) |
TW (1) | TW200901988A (no) |
WO (1) | WO2008117241A2 (no) |
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CN102414184A (zh) * | 2009-05-12 | 2012-04-11 | 埃科特莱茵药品有限公司 | 新型的噁唑烷酮衍生物及其作为食欲素受体拮抗剂的用途 |
AU2010310595B2 (en) | 2009-10-23 | 2015-07-16 | Janssen Pharmaceutica Nv | Disubstituted octahy - dropyrrolo [3,4-c] pyrroles as orexin receptor modulators |
JP5847830B2 (ja) * | 2010-11-10 | 2016-01-27 | アクテリオン ファーマシューティカルズ リミテッドActelion Pharmaceuticals Ltd | オレキシン受容体拮抗薬として有用なラクタム誘導体 |
BR112014019426A8 (pt) | 2012-02-07 | 2017-07-11 | Eolas Therapeutics Inc | Prolinas/ piperidinas substituídas como antagonistas do receptor de orexina |
US9440982B2 (en) | 2012-02-07 | 2016-09-13 | Eolas Therapeutics, Inc. | Substituted prolines/piperidines as orexin receptor antagonists |
LT2855453T (lt) | 2012-06-04 | 2017-02-27 | Actelion Pharmaceuticals Ltd. | Benzimidazolo prolino dariniai |
KR102151288B1 (ko) | 2012-10-10 | 2020-09-03 | 이도르시아 파마슈티컬스 리미티드 | [오르토 바이 (헤테로 )아릴]-[2-(메타 바이 (헤테로 )아릴)-피롤리딘-1-일]-메타논 유도체인 오렉신 수용체 안타고니스트 |
CN105051040A (zh) | 2013-03-12 | 2015-11-11 | 埃科特莱茵药品有限公司 | 作为食欲素受体拮抗剂的氮杂环丁烷酰胺衍生物 |
NO3077389T3 (no) | 2013-12-03 | 2018-02-10 | ||
UA119151C2 (uk) | 2013-12-03 | 2019-05-10 | Ідорсія Фармасьютікалз Лтд | КРИСТАЛІЧНА СОЛЬОВА ФОРМА (S)-(2-(6-ХЛОР-7-МЕТИЛ-1H-БЕНЗО[d]ІМІДАЗОЛ-2-ІЛ)-2-МЕТИЛПІРОЛІДИН-1-ІЛ)(5-МЕТОКСИ-2-(2H-1,2,3-ТРИАЗОЛ-2-ІЛ)ФЕНІЛ)МЕТАНОНУ ЯК АНТАГОНІСТ ОРЕКСИНОВОГО РЕЦЕПТОРА |
PL3077391T3 (pl) | 2013-12-04 | 2019-01-31 | Idorsia Pharmaceuticals Ltd | Zastosowanie pochodnych benzimidazoloproliny |
TW201613902A (en) | 2014-08-13 | 2016-04-16 | Eolas Therapeutics Inc | Difluoropyrrolidines as orexin receptor modulators |
US10894789B2 (en) | 2016-02-12 | 2021-01-19 | Astrazeneca Ab | Halo-substituted piperidines as orexin receptor modulators |
HUE058759T2 (hu) | 2016-03-10 | 2022-09-28 | Janssen Pharmaceutica Nv | Módszerek depresszió kezelésére orexin-2 receptor antagonisták alkalmazásával |
WO2017194548A1 (en) | 2016-05-10 | 2017-11-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for the treatment of autoimmune inflammatory diseases |
RU2643583C1 (ru) * | 2016-10-24 | 2018-02-02 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Уральский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО УГМУ Минздрава России) | Способ лечения хронических болевых синдромов, сформировавшихся на основе посттравматического стрессового расстройства, сочетающегося с последствиями боевой черепно-мозговой травмы |
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WO2020099511A1 (en) | 2018-11-14 | 2020-05-22 | Idorsia Pharmaceuticals Ltd | Benzimidazole-2-methyl-morpholine derivatives |
WO2023218023A1 (en) | 2022-05-13 | 2023-11-16 | Idorsia Pharmaceuticals Ltd | Thiazoloaryl-methyl substituted cyclic hydrazine-n-carboxamide derivatives |
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ES2357992T3 (es) | 2006-12-01 | 2011-05-04 | Actelion Pharmaceuticals Ltd. | Derivados de 3-heteroaril(amino o amido)-1-(bifenil o feniltiazolil)carbonilpiperidina como inhibidores del receptor de orexina. |
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CN102015645B (zh) | 2008-04-30 | 2012-11-14 | 埃科特莱茵药品有限公司 | 哌啶和吡咯烷化合物 |
-
2008
- 2008-03-24 CL CL2008000836A patent/CL2008000836A1/es unknown
- 2008-03-25 CA CA002677991A patent/CA2677991A1/en not_active Abandoned
- 2008-03-25 MX MX2009009690A patent/MX2009009690A/es not_active Application Discontinuation
- 2008-03-25 US US12/593,095 patent/US8236964B2/en not_active Expired - Fee Related
- 2008-03-25 EP EP08719826A patent/EP2125760A2/en not_active Withdrawn
- 2008-03-25 CN CN2008800096488A patent/CN101641342B/zh not_active Expired - Fee Related
- 2008-03-25 JP JP2010500407A patent/JP2010522737A/ja active Pending
- 2008-03-25 BR BRPI0808504-8A patent/BRPI0808504A2/pt not_active Application Discontinuation
- 2008-03-25 KR KR1020097022153A patent/KR20090125195A/ko not_active Application Discontinuation
- 2008-03-25 AU AU2008231441A patent/AU2008231441A1/en not_active Abandoned
- 2008-03-25 WO PCT/IB2008/051110 patent/WO2008117241A2/en active Application Filing
- 2008-03-25 TW TW097110620A patent/TW200901988A/zh unknown
- 2008-03-25 RU RU2009139285/04A patent/RU2009139285A/ru not_active Application Discontinuation
- 2008-03-25 AR ARP080101209A patent/AR065822A1/es unknown
-
2009
- 2009-09-23 IL IL201112A patent/IL201112A0/en unknown
- 2009-10-02 MA MA32243A patent/MA31289B1/fr unknown
- 2009-10-23 NO NO20093200A patent/NO20093200L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL201112A0 (en) | 2010-05-17 |
CN101641342B (zh) | 2012-10-03 |
CL2008000836A1 (es) | 2008-11-07 |
EP2125760A2 (en) | 2009-12-02 |
AR065822A1 (es) | 2009-07-01 |
MA31289B1 (fr) | 2010-04-01 |
JP2010522737A (ja) | 2010-07-08 |
AU2008231441A1 (en) | 2008-10-02 |
WO2008117241A3 (en) | 2008-12-31 |
US20100113531A1 (en) | 2010-05-06 |
CA2677991A1 (en) | 2008-10-02 |
MX2009009690A (es) | 2009-12-14 |
US8236964B2 (en) | 2012-08-07 |
CN101641342A (zh) | 2010-02-03 |
TW200901988A (en) | 2009-01-16 |
RU2009139285A (ru) | 2011-05-10 |
BRPI0808504A2 (pt) | 2014-08-19 |
WO2008117241A2 (en) | 2008-10-02 |
KR20090125195A (ko) | 2009-12-03 |
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