NO20090531L - Fremstilling av ultraren EPA og polare lipider fra hovedsakelig heterotrofe kulturer - Google Patents
Fremstilling av ultraren EPA og polare lipider fra hovedsakelig heterotrofe kulturerInfo
- Publication number
- NO20090531L NO20090531L NO20090531A NO20090531A NO20090531L NO 20090531 L NO20090531 L NO 20090531L NO 20090531 A NO20090531 A NO 20090531A NO 20090531 A NO20090531 A NO 20090531A NO 20090531 L NO20090531 L NO 20090531L
- Authority
- NO
- Norway
- Prior art keywords
- epa
- polar lipids
- ultra
- preparation
- rich
- Prior art date
Links
- 150000002632 lipids Chemical class 0.000 title abstract 5
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 abstract 6
- 229960005135 eicosapentaenoic acid Drugs 0.000 abstract 6
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 abstract 6
- 235000020673 eicosapentaenoic acid Nutrition 0.000 abstract 6
- 241000251468 Actinopterygii Species 0.000 abstract 1
- 241001104939 Nitzschia laevis Species 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000001311 chemical methods and process Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 235000021323 fish oil Nutrition 0.000 abstract 1
- 235000019626 lipase activity Nutrition 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6432—Eicosapentaenoic acids [EPA]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6458—Glycerides by transesterification, e.g. interesterification, ester interchange, alcoholysis or acidolysis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Nutrition Science (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Food Science & Technology (AREA)
- Mycology (AREA)
- Polymers & Plastics (AREA)
- Hematology (AREA)
Abstract
Det er beskrevet eikosapentaensyre (EPA) sammensetninger og EPA-rike polare lipider for profylaktiske eller terapeutiske applikasjoner. Fremstilling fra visse dyrkede mikroorganismer (så som Nitzschia laevis) fremmer syntese av EP A, som inkluderer polare lipider som inkluderer EPA. De EPA-rike polare lipider i seg selv kan anvendes som polare forbindelser. EPA kan selektivt hydrolyseres fra spesielle posisjoner i isolerte polare lipider ved lipaseaktivitet, deretter eventuelt ytterligere renses. Prosessen forbigår avhengigheten av svinnende fiskelagre og på fysikalsk-kjemiske prosesser som ikke adekvat kan separere ønskelige n-3 HUFA' er fra uønskede produkter så som DUA også funnet i fiskeolje og dyrkede organismer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NZ54833906 | 2006-07-05 | ||
PCT/NZ2007/000172 WO2008004900A1 (en) | 2006-07-05 | 2007-07-05 | Production of ultrapure epa and polar lipids from largely heterotrophic culture |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20090531L true NO20090531L (no) | 2009-02-03 |
Family
ID=38894787
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20090531A NO20090531L (no) | 2006-07-05 | 2009-02-03 | Fremstilling av ultraren EPA og polare lipider fra hovedsakelig heterotrofe kulturer |
Country Status (8)
Country | Link |
---|---|
US (3) | US8877465B2 (no) |
EP (1) | EP2044208A4 (no) |
JP (1) | JP5658876B2 (no) |
AU (1) | AU2007270135B9 (no) |
CA (1) | CA2656311C (no) |
NO (1) | NO20090531L (no) |
NZ (1) | NZ573719A (no) |
WO (1) | WO2008004900A1 (no) |
Families Citing this family (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2295594B1 (en) | 2000-01-19 | 2018-04-04 | DSM IP Assets B.V. | Solventless extraction process |
US8343753B2 (en) | 2007-11-01 | 2013-01-01 | Wake Forest University School Of Medicine | Compositions, methods, and kits for polyunsaturated fatty acids from microalgae |
EP4137128A1 (en) | 2008-09-02 | 2023-02-22 | Amarin Pharmaceuticals Ireland Limited | Pharmaceutical composition comprising eicosapentaenoic acid and a statin, and methods of using same |
NZ594395A (en) | 2009-02-10 | 2014-01-31 | Amarin Pharmaceuticals Ie Ltd | Use of eicosapentaenoic acid ethyl ester for treating hypertriglyceridemia |
MX2011011538A (es) | 2009-04-29 | 2012-06-13 | Amarin Pharma Inc | Composicion farmaceutica estable y metodos de uso de la misma. |
NZ720946A (en) | 2009-04-29 | 2017-09-29 | Amarin Pharmaceuticals Ie Ltd | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
SI3318255T1 (sl) | 2009-06-15 | 2021-07-30 | Amarin Pharmaceuticals Ireland Limited | Kompozicije in metode za zdravljenje kapi pri subjektu, ki prejema sočasno zdravljenje s statinom |
US8399226B2 (en) | 2009-06-16 | 2013-03-19 | E I Du Pont De Nemours And Company | High eicosapentaenoic acid oils from improved optimized strains of Yarrowia lipolytica |
CN101613724B (zh) * | 2009-07-28 | 2011-04-06 | 嘉吉烯王生物工程(湖北)有限公司 | 重复利用高山被孢霉菌粕制备花生四烯酸的方法 |
KR101856055B1 (ko) * | 2009-09-18 | 2018-05-09 | 파이코일 바이오테크놀로지 인터내셔널, 아이엔씨. | 조절되는 조명을 사용하는 미세조류 발효 |
CA2775339C (en) | 2009-09-23 | 2017-03-28 | Amarin Corporation Plc | Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same |
ES2862980T3 (es) * | 2009-12-30 | 2021-10-08 | Basf Pharma Callanish Ltd | Composiciones de ácido graso poliinsaturado obtenibles mediante un proceso de separación cromatográfica en lecho móvil simulado |
AU2013204090B2 (en) * | 2009-12-30 | 2015-01-29 | Basf Pharma (Callanish) Limited | Simulated moving bed chromatographic separation process |
DK2526197T3 (en) | 2010-01-19 | 2018-10-01 | Dsm Ip Assets Bv | MICRO; PRODUCING EICOSAPENTAIC ACID AND DOCOSAHEXAENIC ACID, FATIC ACID COMPOSITIONS, AND METHODS FOR PREPARING AND USING THEREOF |
KR20130026428A (ko) * | 2010-03-04 | 2013-03-13 | 아마린 파마, 인크. | 심혈관 질환을 치료 및/또는 예방하기 위한 조성물 및 방법 |
EP2576801B1 (en) | 2010-06-01 | 2019-10-02 | DSM IP Assets B.V. | Extraction of lipid from cells and products therefrom |
EP3527665A1 (en) | 2010-06-09 | 2019-08-21 | Fermentalg | Compositions comprising eicosapentaenoic acid suitable for high purification |
FR2964667B1 (fr) * | 2010-09-15 | 2014-08-22 | Fermentalg | Procede de culture d'algues unicellulaires mixotrophes en presence d'un apport lumineux discontinu sous forme de flashs |
AU2011312987A1 (en) * | 2010-10-06 | 2013-05-02 | Photonz Corporation Limited | Heterotrophic microbial production of xanthophyll pigments |
US10479969B2 (en) | 2010-10-11 | 2019-11-19 | Phycoil Biotechnology International. Inc. | Utilization of wastewater for microalgal cultivation |
US11712429B2 (en) | 2010-11-29 | 2023-08-01 | Amarin Pharmaceuticals Ireland Limited | Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity |
AU2011336856A1 (en) * | 2010-11-29 | 2013-07-04 | Amarin Pharmaceuticals Ireland Limited | Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity |
WO2012103685A1 (en) * | 2011-02-01 | 2012-08-09 | Nippon Suisan Kaisha, Ltd. | Sexual function improving agent |
CN103327982A (zh) * | 2011-02-01 | 2013-09-25 | 日本水产株式会社 | 性功能改善剂 |
AU2012214260A1 (en) * | 2011-02-11 | 2013-07-25 | E. I. Du Pont De Nemours And Company | An eicosapentaenoic acid concentrate |
GB201111589D0 (en) | 2011-07-06 | 2011-08-24 | Equateq Ltd | New modified process |
GB201111594D0 (en) | 2011-07-06 | 2011-08-24 | Equateq Ltd | New improved process |
GB201111595D0 (en) | 2011-07-06 | 2011-08-24 | Equateq Ltd | Improved process |
GB201111601D0 (en) | 2011-07-06 | 2011-08-24 | Equateq Ltd | New process |
GB201111591D0 (en) | 2011-07-06 | 2011-08-24 | Equateq Ltd | Further new process |
CN105410925A (zh) | 2011-07-21 | 2016-03-23 | 帝斯曼知识产权资产管理有限公司 | 脂肪酸组合物 |
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EP2044208A1 (en) | 2009-04-08 |
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