NO20082507L - Fremgangsmate for fremstilling av beta-(fluorfenyl)-propanoatesterderivater - Google Patents
Fremgangsmate for fremstilling av beta-(fluorfenyl)-propanoatesterderivaterInfo
- Publication number
- NO20082507L NO20082507L NO20082507A NO20082507A NO20082507L NO 20082507 L NO20082507 L NO 20082507L NO 20082507 A NO20082507 A NO 20082507A NO 20082507 A NO20082507 A NO 20082507A NO 20082507 L NO20082507 L NO 20082507L
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- formula
- fluorophenyl
- beta
- ester derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/96—Sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C67/347—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to unsaturated carbon-to-carbon bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
- C07C69/533—Monocarboxylic acid esters having only one carbon-to-carbon double bond
- C07C69/54—Acrylic acid esters; Methacrylic acid esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
En fremgangsmåte for fremstilling av en forbindelse med formel (I): som omfatter å reagere en forbindelse med formel (II): Med en fluorinert bortype med formel (III): i nærvær av: en alkohol; en rodium (I) prekatalysatortype; et egnet ligand som binder seg til et rodium (I) prekatalysatortypen for å danne et katalysatorkompleks; en base; og et egnet løsningsmiddel; der fremgangsmåten utføres ved en temperatur i området 40 til 110°C. Forbindelsene med formel (I) er nyttige ved fremstillingen av farmasøytisk aktive forbindelser.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0502515 | 2005-11-16 | ||
PCT/GB2006/004205 WO2007057643A1 (en) | 2005-11-16 | 2006-11-13 | Process for preparing beta- (fluorophenyl) -propanoate ester derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20082507L true NO20082507L (no) | 2008-06-03 |
Family
ID=37734255
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20082507A NO20082507L (no) | 2005-11-16 | 2008-06-03 | Fremgangsmate for fremstilling av beta-(fluorfenyl)-propanoatesterderivater |
Country Status (14)
Country | Link |
---|---|
US (1) | US20090111993A1 (no) |
EP (1) | EP1951652A1 (no) |
JP (1) | JP2009515937A (no) |
KR (1) | KR20080067661A (no) |
CN (1) | CN101309891A (no) |
AR (1) | AR057605A1 (no) |
AU (1) | AU2006314271A1 (no) |
BR (1) | BRPI0618617A2 (no) |
CA (1) | CA2627552A1 (no) |
IL (1) | IL191056A0 (no) |
NO (1) | NO20082507L (no) |
TW (1) | TW200804269A (no) |
WO (1) | WO2007057643A1 (no) |
ZA (1) | ZA200803943B (no) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2447245A1 (en) * | 2010-10-28 | 2012-05-02 | Cognis IP Management GmbH | A method to prepare beta-functionalized aliphatic esters |
KR20200094762A (ko) | 2017-12-01 | 2020-08-07 | 바이엘 파마 악티엔게젤샤프트 | 제약 성분으로서 사용하기 위한 (3s)-3-(4-클로르-3-{[(2s,3r)-2-(4-클로르페닐)-4,4,4-트리플루오르-3-메틸부타노일]아미노}페닐)-3-시클로-프로필프로판산 및 그의 결정질 형태를 제조하는 방법 |
CN111138350B (zh) * | 2020-01-03 | 2021-08-10 | 中国药科大学 | 一种右氯苯那敏和右溴苯那敏的不对称合成方法 |
CN111517954A (zh) * | 2020-06-08 | 2020-08-11 | 浙江师范大学 | 一种(z)-5-氟-2-二氟亚甲基烯烃衍生物及其制备方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE0403106D0 (sv) * | 2004-12-20 | 2004-12-20 | Astrazeneca Ab | Chemical compounds |
-
2006
- 2006-11-03 TW TW095140756A patent/TW200804269A/zh unknown
- 2006-11-13 JP JP2008540676A patent/JP2009515937A/ja active Pending
- 2006-11-13 CA CA002627552A patent/CA2627552A1/en not_active Abandoned
- 2006-11-13 KR KR1020087011591A patent/KR20080067661A/ko not_active Application Discontinuation
- 2006-11-13 CN CNA2006800426258A patent/CN101309891A/zh active Pending
- 2006-11-13 AU AU2006314271A patent/AU2006314271A1/en not_active Abandoned
- 2006-11-13 EP EP06808498A patent/EP1951652A1/en not_active Withdrawn
- 2006-11-13 BR BRPI0618617-3A patent/BRPI0618617A2/pt not_active Application Discontinuation
- 2006-11-13 WO PCT/GB2006/004205 patent/WO2007057643A1/en active Application Filing
- 2006-11-13 US US12/093,664 patent/US20090111993A1/en not_active Abandoned
- 2006-11-16 AR ARP060105034A patent/AR057605A1/es unknown
-
2008
- 2008-04-27 IL IL191056A patent/IL191056A0/en unknown
- 2008-05-08 ZA ZA200803943A patent/ZA200803943B/xx unknown
- 2008-06-03 NO NO20082507A patent/NO20082507L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL191056A0 (en) | 2008-12-29 |
US20090111993A1 (en) | 2009-04-30 |
AR057605A1 (es) | 2007-12-05 |
TW200804269A (en) | 2008-01-16 |
CN101309891A (zh) | 2008-11-19 |
CA2627552A1 (en) | 2007-05-24 |
AU2006314271A1 (en) | 2007-05-24 |
JP2009515937A (ja) | 2009-04-16 |
BRPI0618617A2 (pt) | 2011-09-06 |
ZA200803943B (en) | 2009-03-25 |
KR20080067661A (ko) | 2008-07-21 |
WO2007057643A1 (en) | 2007-05-24 |
EP1951652A1 (en) | 2008-08-06 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |