NO20080536L - Oksazolidinonderivater og deres anvendelse som antibiotika - Google Patents

Oksazolidinonderivater og deres anvendelse som antibiotika

Info

Publication number
NO20080536L
NO20080536L NO20080536A NO20080536A NO20080536L NO 20080536 L NO20080536 L NO 20080536L NO 20080536 A NO20080536 A NO 20080536A NO 20080536 A NO20080536 A NO 20080536A NO 20080536 L NO20080536 L NO 20080536L
Authority
NO
Norway
Prior art keywords
compounds
antibiotics
different meanings
gram
oxazolidinone derivatives
Prior art date
Application number
NO20080536A
Other languages
English (en)
Inventor
Antonio Guglietta
Montserrat Cano
Albert Palomer
Original Assignee
Ferrer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34982564&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20080536(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ferrer Int filed Critical Ferrer Int
Publication of NO20080536L publication Critical patent/NO20080536L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

der A er visse heterosykler som eventuelt er substituert; Ri, R2, R3 og R4 uavhengig er valgt blant -H og halogen; X er valgt blant O, S, NR9 og CR9R10; R9 og Rio har forskjellige betydninger; Y er valgt blant O, S, SO, SO2, NO, NR]2 og CRi2Ri3; R12 og Ri3 har forskjellige betydninger. Det tilveiebringes videre forskjellige prosesser for fremstilling av slike forbindelser. Oksazolidinonforbindelsene med formel (I) er aktive mot grampositive og noen gramnegative human- og veterinærpatogener med en svak monoaminoksidase(MAO)-inhibitorisk aktivitet. Forbindelsene finner anvendelse ved behandling av bakterielle infeksjoner.
NO20080536A 2005-06-27 2008-01-28 Oksazolidinonderivater og deres anvendelse som antibiotika NO20080536L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05105714A EP1745784A1 (en) 2005-06-27 2005-06-27 Oxazolidinone derivatives and use thereof as antibiotics
PCT/EP2006/063541 WO2007000432A1 (en) 2005-06-27 2006-06-26 Oxazolidinone derivatives and use thereof as antibiotics

Publications (1)

Publication Number Publication Date
NO20080536L true NO20080536L (no) 2008-03-14

Family

ID=34982564

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20080536A NO20080536L (no) 2005-06-27 2008-01-28 Oksazolidinonderivater og deres anvendelse som antibiotika

Country Status (23)

Country Link
US (1) US7759351B2 (no)
EP (2) EP1745784A1 (no)
JP (1) JP2008543963A (no)
KR (1) KR20080020696A (no)
CN (1) CN101248067A (no)
AR (1) AR054625A1 (no)
AT (1) ATE442366T1 (no)
AU (1) AU2006263880A1 (no)
BR (1) BRPI0612559A2 (no)
CA (1) CA2612969A1 (no)
CY (1) CY1109544T1 (no)
DE (1) DE602006009112D1 (no)
DK (1) DK1902050T3 (no)
ES (1) ES2333469T3 (no)
HK (1) HK1116482A1 (no)
MX (1) MX2007016329A (no)
NO (1) NO20080536L (no)
PL (1) PL1902050T3 (no)
PT (1) PT1902050E (no)
RU (1) RU2417223C2 (no)
SI (1) SI1902050T1 (no)
TW (1) TWI324603B (no)
WO (1) WO2007000432A1 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8138191B2 (en) 2007-01-11 2012-03-20 Critical Outcome Technologies Inc. Inhibitor compounds and cancer treatment methods
WO2009079797A1 (en) 2007-12-26 2009-07-02 Critical Outcome Technologies, Inc. Compounds and method for treatment of cancer
AU2009318783A1 (en) 2008-11-20 2011-06-23 Panacea Biotec Ltd. Novel antimicrobials
CN102803224A (zh) 2009-06-26 2012-11-28 万能药生物有限公司 新的氮杂双环己烷类化合物
CA2999435A1 (en) 2010-04-01 2011-10-06 Critical Outcome Technologies Inc. Compounds and method for treatment of hiv
EP3020710A4 (en) * 2013-07-11 2016-12-14 Consejo Superior De Investig Científicas (Csic) OXAZOLIDINONE DERIVATIVES AS PPAR LIGANDS
CN103420995B (zh) * 2013-09-07 2015-07-01 吉首大学 噁唑烷酮-烷胺基-呋喃酮型化合物及其制法和用途
CN104447730B (zh) * 2014-12-05 2017-11-07 广东东阳光药业有限公司 噁唑烷酮类化合物及其在药物中的应用
TWI614256B (zh) 2017-05-26 2018-02-11 合成四氫異喹啉噁唑烷的方法
KR102152445B1 (ko) * 2017-09-28 2020-09-04 주식회사 엘지화학 의약품 합성용 중간체 화합물의 제조 방법
CA3183397A1 (en) 2020-06-18 2021-12-23 Daryl C. Drummond Oxazolidinone compounds, liposome compositions comprising oxazolidinone compounds and methods of use thereof
CN115466253A (zh) * 2021-06-16 2022-12-13 沈阳药科大学 含二硫代氨基甲酸酯结构的噁唑烷酮类化合物及其制备方法
CN113880821B (zh) * 2021-10-29 2024-03-12 南京碳硅人工智能生物医药技术研究院有限公司 一类双光子荧光探针对癫痫脑内次氯酸特征成像的荧光探针设计及其合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005511688A (ja) * 2001-11-29 2005-04-28 メルク アンド カンパニー インコーポレーテッド シクロプロピル含有オキサゾリジノン抗生物質及びその誘導体
CA2492194A1 (en) * 2002-07-11 2004-01-22 Wockhardt Limited Antibacterial cyano-(substituted)-methylenepiperidinophenyl oxazolidinones targeting multiple ribonucleoproteins sites
EP1620433A1 (en) * 2003-04-07 2006-02-01 Ranbaxy Laboratories, Ltd. Oxazolidinone derivatives as antimicrobials

Also Published As

Publication number Publication date
DE602006009112D1 (de) 2009-10-22
HK1116482A1 (en) 2008-12-24
ES2333469T3 (es) 2010-02-22
RU2008102597A (ru) 2009-08-10
ATE442366T1 (de) 2009-09-15
CA2612969A1 (en) 2007-01-04
EP1902050B1 (en) 2009-09-09
SI1902050T1 (sl) 2010-01-29
BRPI0612559A2 (pt) 2010-11-23
US7759351B2 (en) 2010-07-20
CY1109544T1 (el) 2014-08-13
EP1902050A1 (en) 2008-03-26
JP2008543963A (ja) 2008-12-04
KR20080020696A (ko) 2008-03-05
AU2006263880A1 (en) 2007-01-04
AR054625A1 (es) 2007-07-04
RU2417223C2 (ru) 2011-04-27
CN101248067A (zh) 2008-08-20
MX2007016329A (es) 2008-03-10
PL1902050T3 (pl) 2010-03-31
US20090062266A1 (en) 2009-03-05
TWI324603B (en) 2010-05-11
EP1745784A1 (en) 2007-01-24
WO2007000432A1 (en) 2007-01-04
PT1902050E (pt) 2009-11-27
TW200740800A (en) 2007-11-01
DK1902050T3 (da) 2010-01-04

Similar Documents

Publication Publication Date Title
NO20080536L (no) Oksazolidinonderivater og deres anvendelse som antibiotika
NO20085067L (no) 4,5-difenyl-pyrimidinyl substituerte karboksylsyrer, fremgangsmate for deres fremstilling og anvendelse derav som medikamenter
LTC1699784I2 (lt) Nauji oksazolidinono dariniai
NO20061050L (no) 7-(4-Substituerte-3-Cyclopropylaminometyl-1-Pyrrolidin yl)Kinolon-karboksylsyrederivater
NO20074993L (no) Bisykliske [3 0 1]heteroaryl amider som type 1 glysin transport inhibitorer
ATE319710T1 (de) Antimikrobielle chinolonderivate und ihre verwendung zur behandlung bakterieller infektionen
WO2006087543A8 (en) Antibacterial piperidine derivatives
NO20055421L (no) Kinolinderivater som fosfodiestrase-inhibitorer
WO2007069020A3 (en) N-hydroxyamide derivatives possessing antibacterial activity
TW200738692A (en) New substituted glycinamides, process for their manufacture and use thereof as medicaments
NO20082629L (no) Macrocyklisk factor VIIa-inhibitorer anvendbare som antikoagulanter
NO331012B1 (no) N-sulfonyl-4-metylenamino-3-hydroksy-2-pyridoner som antimikrobielle midler
ATE476431T1 (de) Piperidin- und azetidinderivate als glyt1- inhibitoren
NO20035791L (no) Nye derivater av oksazolidinoner som antibakterielle midler
WO2006120563A3 (en) Antibacterial agents
NO20080394L (no) N-(arylalkyl)-1H-pyrrolopyridin-2-karboksamidderivater, fremstilling og anvendelse derav
NO20075270L (no) Antibakterielle amid-makrocykler V
NO20070870L (no) Oksazolidinonforbindelser og sammensetninger og fremgangsmater relatert dertil
NO20092655L (no) 2-kinolinon- og 2-kinoksalinonderivater og deres anvendelse som antibakterielle midler
GEP20084437B (en) Novel lincomycin derivatives possessing antimicrobial activity
SG166798A1 (en) Quinolone derivatives as antibacterial agents
NO20044548L (no) Fremgangsmate for fremstilling av 6-alkaliden-penemderivater
TW200612907A (en) New compounds
EP1336611A4 (en) DIHALOGENIC COMPOUNDS
NO20014234L (no) Pyrazol-3-on-derivater som faktor-Xa-inhibitorer

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application